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公开(公告)号：CA2132959C
公开(公告)日：2006-01-24
申请号：CA2132959
申请日：1993-03-24
Applicant: ABBOTT LAB
Inventor： TAYI APPARAO , VAUGHT JAMES A , YOST DAVID A , RUMBAUGH WILLIAM , WINTER GARY E , HANCE ROBERT B , STANTON ALYN K , OLEKSAK CARL M , WATKINS WILLIAM E III , VICKSTROM RICHARD L , CLOONAN KEVIN M , WOHLFORD ROBERT A , HILLS DAVID B JR , SCHRIER PAUL R , CLARK FREDERIC L , CLIFT GILBERT , HENDRICK KENDALL B , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MITCHELL JAMES E , MOORE LARRY W , PENNINGTON CHARLES D , WALKER EDNA S , SMITH B JANE
IPC: G01N35/00 , B01L3/00 , B01L3/08 , B01L9/06 , G01F11/04 , G01M11/00 , G01N1/00 , G01N1/14 , G01N1/28 , G01N21/03 , G01N21/25 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/02 , G01N35/04 , G01N35/10 , G05D23/00 , G05D23/19 , H01J49/04 , H02P8/00 , H04B15/00 , H05B39/04 , H05B41/00 , H05B41/36
Abstract: An automated, continuous and random access analytical system, having apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated. continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample (26), reagents (30) to a reaction vessel (34) without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable (34) to a process work station, whereby a mixture of the unit dose disposabl e reagents and sample (34) are achieved during incubation. The system is capable of performing more than one scheduled assa y in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually byat least two assay procedures.
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Patent Agency Ranking
公开(公告)号：CA2172363A1
公开(公告)日：1995-03-31
申请号：CA2172363
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT JAMES A , VICKSTROM RICHARD L , WALKER DONNY RAY , WATKINS WILLIAM E III , WINTER GARY E , WOHLFORD ROBERT A , CLIFT GILBERT , CLOONAN KEVIN M , MITCHELL JAMES E , STANTON ALYN K , YOST DAVID A , HILLS DAVID B
IPC: G01N33/483 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N37/00
Abstract: An automated, continuous and random access analytical system, having apparat us and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodolo gies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is a lso disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assa ys of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a u nit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reacti on sequence, followed by physical transfer of the unit dose disposable to a processing wo rkstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performi ng more than one scheduled assay in any order, and assay s where more than such scheduled assays are presented. The automated, continuo us and random access analytical system is also capable o f analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.
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公开(公告)号：CA2650259A1
公开(公告)日：1995-03-30
申请号：CA2650259
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： HENDRICK KENDALL B , MOORE LARRY W , CLOONAN KEVIN M , CLARK FREDERICK L , CLIFT GILBERT , WATKINS WILLIAM E III , KANEWSKE WILLIAM J III , VICKSTROM RICHARD L , MCDOWELL DOUGLAS D
IPC: B65D47/08 , G01N33/483 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: A capped-closure mounted on a container for storing reagents for use in an automated analytical instrument having an actuating device mounted thereon. The capped-closure comprises a base being generally cylindrical, wherein the bas e has one end opening to the container and the other end having an opening through whi ch the reagents can be aspirated. The capped-closure further comprises a lever assembly pivotally mounted on the base. The lever assembly has one end which forms a cap operable to seal the opening the base sufficiently tightly to prevent evaporation from the container. The other end of the lever assembly forms a tab operable to pivot the lever assembly to a substantially perpendicular position with opening of the base when depressed for exposing the opening of the base to a device for aspirating th e reagent from the container. The capped-closure finally comprises spring mechanism connect ed between the base and the lever assembly for urging the lever assembly to the substantially perpendicular position.
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公开(公告)号：CA2613156A1
公开(公告)日：1995-03-30
申请号：CA2613156
申请日：1994-09-22
Applicant: ABBOTT LAB
Inventor： TAYI APPARAO , KANEWSKE WILLIAM J III , VAUGHT JAMES A , YOST DAVID A , HILLS DAVID B , LAGOCKI PETER A , WINTER GARY E , VICKSTROM RICHARD L , STANTON ALYN K , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , MARTIN RICHARD R , OLEKSAK CARL M , MITCHELL JAMES E , SCHMIDT LINDA S , WALKER DONNY RAY , WATKINS WILLIAM E III , HENDRICK KENDALL B , WALKER EDNA S , SPRONK ADRIAN M , WOHLFORD ROBERT A , SMITH JANE B , RUMBAUGH WILLIAM D , MOORE LARRY W , MERRIAM RICHARD A , CLOONAN KEVIN M , SCHRIER PAUL R , CLARK FREDERICK L , CLEMENS JOHN M , MCDOWELL DOUGLAS D , HANCE ROBERT B , CLIFT GILBERT
IPC: G01N33/483 , G01N35/00 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N1/44 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/02 , G01N35/04 , G01N35/10 , G01N37/00 , H01J49/04
Abstract: The invention discloses an automated liquid level sensing system for detecting the presence of liquid in a container, comprising an electrically conductive and movable probe positioned above said container; a signal source electrically connected to said probe, said signal source capable of energizing said probe thereby causing said probe to transmit said electrical signal at a given frequency; a receiving antenna and means for transferring said received electrical signal from said receiving antenna to an analyzing means; wherein analyzing said received electrical signal includes: (1) means for detecting changes in received signal amplitude, wherein said means for detecting changes in received signal amplitude includes:(a) means for multiplying said received signal by a reference signal, said reference signal having a frequency substantially equal to the frequency of the transmitted signal; and (b) a low pass filter through which is passed said multiplied received signal; and (2) means for measuring rate of change of said change in received signal amplitude; and means connected to said analyzing means for indicating that liquid has been detected. The invention further discloses a method of automatically detecting the presence of liquid in a container using the system of the invention. An automated liquid sensing system for use in a clinical analysis system having a pipettor for dispensing or aspirating liquid in a container, the pipettor being electrically conductive and moveable vertically into the container, using the automated liquid sensing system of the invention further comprising a means electrically connected to the pipettor for applying a RF signal thereto and causing the pipettor to radiate an electromagnetic field, the propagation of which changes when the pipettor contacts the surface of the liquid in the container is further disclosed.
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公开(公告)号：AU3934993A
公开(公告)日：1993-11-08
申请号：AU3934993
申请日：1993-03-24
Applicant: ABBOTT LAB
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公开(公告)号：CA2129246A1
公开(公告)日：1993-10-14
申请号：CA2129246
申请日：1993-03-24
Applicant: ABBOTT LAB
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