公开(公告)号：DE19601558A1

公开(公告)日：1997-07-24

申请号：DE19601558

申请日：1996-01-17

Applicant: BASF AG

Inventor： KAIBEL GERD DR ,  STROEZEL MANFRED ,  RHEUDE UDO DR ,  GRAAUW JAN DE PROF DR ,  OLUJIC ZARKO DR ,  FREY GUENTHER ,  JANSEN HELMUT

IPC: B01D3/28 ,  B01J19/32 ,  B01D3/14

公开(公告)号：DE59500101D1

公开(公告)日：1997-03-13

申请号：DE59500101

申请日：1995-03-02

Applicant: BASF AG

Inventor： JOHN MICHAEL DR ,  RHEUDE UDO DR ,  PAUST JOACHIM DR ,  MEYER JOACHIM DR

IPC: C07C29/32 ,  C07C29/40 ,  C07C35/17 ,  C07C35/18 ,  C07C43/184 ,  C07C43/188 ,  C07C45/58 ,  C07C49/337 ,  C07C49/35 ,  C07C49/537 ,  C07C49/577 ,  C07C67/293 ,  C07C69/78 ,  C07C69/96 ,  C07D303/14 ,  C07D303/16 ,  C07D303/22 ,  C07D309/12 ,  C07D407/12 ,  C07F7/18

Abstract: Prodn. of 1,2,2-trimethyl- cyclopentylmethylketone derivs. of formula (I) comprises (A) (i) reacting a 2,2,6-tri- methyl-cyclohexane-1-one of formula (II) with a methylcarbanion of formula CH3 M (III) and converting the resulting 1,4-dihydroxy-1,2,2,6-tetramethylcyclohexane deriv. of formula (IV) into a mixt. of the corresp. cpds. (V) and (VI) by acid catalysed elimination of the tert. hydroxyl gp., or (A) (ii) the 2,2,6-trimethylcyclohexane-1-one cpd. (II) may be converted directly into the cpd. (VI) by a Wittig reaction with a triphenylmethylenephosphorane cpd. of formula (C6H5)3P=CH2 (VII); (B) converting the cpd. (VI) into the cpd. (V) by acid catalysed isomerisation of the double bond; (C) epoxidising the double bond in the cpd. (V) in the known way by reacting with peroxyacids, their salts or hydroperoxides to form the 7-oxa-bicycloÄ4.1.0Üheptane cpd. of formula (VIII) and (D) converting the cpd. (VIII) into the 1,2,2-tri- methyl-cyclopentylmethylketone cpd. (I) by reaction with Lewis acids and opt. splitting off the protective gp. from the O atom. R=H, alkyl, aryl, arylmethyl, trialkylsilyl, triarylsilyl, alkylarylsilyl, alkyloxyalkyl, tetrahydropyranyl, arylmethyloxycarbonyl, alkanoyl or benzoyl residue; M =Li, MgCl, MgBr or MgI.

公开(公告)号：DK0547422T3

公开(公告)日：1996-04-01

申请号：DK92120456

申请日：1992-12-01

Applicant: BASF AG

Inventor： SCHNEIDER JOACHIM U DR ,  RHEUDE UDO DR ,  BEWERT WOLFGANG DR ,  SCHUMACHER HORST DR ,  GAUS GUENTER DR

IPC: A61K9/16 ,  A61K9/50 ,  A61K31/015 ,  A61K47/18 ,  A61K9/14 ,  A61K47/42 ,  A61P3/02

Abstract: Process for the production of stable dry powders which are insoluble in hot water and which contain fat-soluble vitamins and/or carotenoids, which comprises the following process steps: a) preparation of an aqueous dispersion containing essentially these fat-soluble active substances, film-forming colloids and reducing sugars, b)conversion of this dispersion into dry powders of vitamin and/or carotenoid products and c) thermal hardening of the powder at temperatures of 60 to 180 DEG C, and which is characterised in that gelatin in combination with one or more organic amino compounds which are free or bound as salts and which contain a basic primary amino group and additionally either another amino group, a hydroxyl group, an alkoxy group or a carboxyl group, and/or in combination with sufficient basic alkali metal or alkaline earth metal compound for the dispersion to have a pH of 7.5 to 10, is used as film-forming colloid, and the dry powders obtainable by this process are described.

公开(公告)号：DE59201251D1

公开(公告)日：1995-03-09

申请号：DE59201251

申请日：1992-03-24

Applicant: BASF AG

Inventor： FRANK JUERGEN DR ,  RHEUDE UDO DR ,  SCHULZ BERNHARD DR ,  PAUST JOACHIM DR ,  HICKMANN ECKHARD DR

IPC: B01J27/128 ,  B01J27/138 ,  C07B61/00 ,  C07C47/21 ,  C07C403/24 ,  C07D307/28

公开(公告)号：DE4322277A1

公开(公告)日：1995-01-12

申请号：DE4322277

申请日：1993-07-05

Applicant: BASF AG

Inventor： ERNST HANSGEORG DR ,  PAUST JOACHIM DR ,  RHEUDE UDO DR

IPC: C07C41/18 ,  C07C45/45 ,  C07C49/303 ,  C07C403/24 ,  C07D317/46 ,  C07D317/50 ,  C07D317/54 ,  C07D407/06 ,  C07D407/12 ,  C07F9/54 ,  C09B23/10 ,  C07C43/184

Abstract: Compounds of the general formula I in which R is H or C1-C4-alkyl, R is C1-C4-alkyl and R is an ether, silyl ether or acetal protective group which can be converted into a hydroxyl group by hydrolysis, in particular one of the radicals and a process for the production of these compounds by reacting an alkenyne of the general formula II in an inert solvent with additional use of lithium amide with a cyclohexenone of the general formula III and the use of the compounds of the formula I for the production of astaxanthin.