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公开(公告)号:JP2000189064A
公开(公告)日:2000-07-11
申请号:JP25061799
申请日:1999-09-03
Applicant: BASF AG
Inventor: FRIEDRICH THOMAS DR , BEWERT WOLFGANG DR , LUEDDECKE ERIK DR , KLINGLER JUERGEN DR , HEGER ROBERT DR
IPC: A23B5/00 , A23J3/00 , A23J3/04 , A23J3/06 , A23J3/10 , A23J3/16 , A23J3/18 , A23K1/00 , A23K1/16 , A23K1/165 , A23L1/00 , A23L33/15 , A23P1/04 , A61K9/16 , A61K38/00 , C12N9/06
Abstract: PROBLEM TO BE SOLVED: To obtain an active component compound that is convenient, economic and applicable over a wide range, has excellent sustained release properties, efficacy persistency, and is useful in medicinal compositions, foods, feeds for animals, and the like by surrounding active components with a coating layer made of a protein crosslinked with a specific enzyme. SOLUTION: One or more kinds of vitamins, enzymes, additives for foods, additives for feeds and other active components are surrounded with a part of a coating layer made of a protein crosslinked with one or more kinds of enzymes selected from lipoxygenase, protein disulfide isomerase, phenol oxidase, phenol peroxidase, lysyl oxidase, protein disulfide reductase, tyrosine oxidase, or sulfhydryl oxidase to give an active component compound. It is preferable that the mass ratio of the active components to the protein is in the range of from 1/100 to 5/1 and the active ingredients are hydrophobic.
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公开(公告)号:JP2001078718A
公开(公告)日:2001-03-27
申请号:JP24185099
申请日:1999-08-27
Applicant: BASF AG
Inventor: BEWERT WOLFGANG DR , BETZ ROLAND DIPL ING , LUEDDECKE ERIK DR , FRIEDRICH THOMAS DR
IPC: A23J3/00 , A23L3/3463 , A23L33/17 , A23L1/305 , A23K1/14
Abstract: PROBLEM TO BE SOLVED: To avoid the use of an aldehyde as a cross-linking agent and obtain an active ingredient preparation excellent in safety and useful for a food, a feed, etc. by carrying out an atomization of a cross-linkable protein, a transglutaminase and the active ingredient under specific conditions. SOLUTION: (A) A cross-linkable protein selected from the group of gelatin, casein, soybean proteins, corn proteins and collagen is completely mixed with a transglutaminase derived from a microorganism and an aqueous solution of an active ingredient such as a vitamin, a human food additive or an animal feed additive and the ratio of the active ingredient to the protein is (1:10) to (4:1) expressed in terms of weight. Furthermore, an atomization of the resultant mixture is then carried out in an inert gas atmosphere loaded with a hydrophobic silica, corn starch or a hydrophobic corn starch to produce an active ingredient preparation. The resultant preparation is preferably further dried until the residual moisture content is below 10 wt.% subsequently to the atomization.
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公开(公告)号:DE59205688D1
公开(公告)日:1996-04-18
申请号:DE59205688
申请日:1992-12-01
Applicant: BASF AG
Inventor: SCHNEIDER JOACHIM U DR , SCHUMACHER HORST DR , BEWERT WOLFGANG DR , GAUS GUENTER DR , RHEUDE UDO DR
Abstract: Process for the production of stable dry powders which are insoluble in hot water and which contain fat-soluble vitamins and/or carotenoids, which comprises the following process steps: a) preparation of an aqueous dispersion containing essentially these fat-soluble active substances, film-forming colloids and reducing sugars, b)conversion of this dispersion into dry powders of vitamin and/or carotenoid products and c) thermal hardening of the powder at temperatures of 60 to 180 DEG C, and which is characterised in that gelatin in combination with one or more organic amino compounds which are free or bound as salts and which contain a basic primary amino group and additionally either another amino group, a hydroxyl group, an alkoxy group or a carboxyl group, and/or in combination with sufficient basic alkali metal or alkaline earth metal compound for the dispersion to have a pH of 7.5 to 10, is used as film-forming colloid, and the dry powders obtainable by this process are described.
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公开(公告)号:DE2111672A1
公开(公告)日:1972-09-21
申请号:DE2111672
申请日:1971-03-11
Applicant: BASF AG
Inventor: BEWERT WOLFGANG DR , WUNSCH GERD DR , ADOLPHI HEINRICH DR
Abstract: Title esters of the formula (where R1 and R2 are lower R1R2P-(S)n-CO-CO-R4 alkoxy or lower alkyl, R4 is lower alkoxy, phenoxy or lower dialkylamino, and n is 0 or 1), which are esp. active against Musca domestica, Fannia canicularis, Ceratitis capitata, Dacus oleae and Lucilia sericata, are prepd. by reacting a cpd. R1R2-P-R3 (where R3 is OCH3, OC2H5, SCH3 or SC2H5) with a cpd. halogen-CO-CO-R4. The reaction can be carried out in the presence of absence of solvents at 20-130 degrees C.
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公开(公告)号:DE58901641D1
公开(公告)日:1992-07-23
申请号:DE58901641
申请日:1989-01-20
Applicant: BASF AG
Inventor: FUKAMACHI CHIHARU , SCHUMACHER HORST DR , BEWERT WOLFGANG DR , SCHNEIDER JOACHIM DR
IPC: C07B63/04 , A61K9/14 , A61K9/16 , A61K31/07 , A61K31/355 , A61K31/59 , A61K47/18 , A61K47/44 , A61K9/50 , A61K47/02 , A61K47/26
Abstract: A stable mixture of an oxidation-sensitive compound contains triglycerides, complexing agents and coating substances as well as the oxidation-sensitive compound.
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公开(公告)号:CH529791A
公开(公告)日:1972-10-31
申请号:CH1160072
申请日:1972-08-04
Applicant: BASF AG
Inventor: ADOLPHI HEINRICH DR , BEWERT WOLFGANG DR , KIENER VOLKER DR , WUNSCH GERD DR
IPC: C07F9/6581 , C07D105/02 , A01N9/36
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公开(公告)号:DE2110532A1
公开(公告)日:1972-09-07
申请号:DE2110532
申请日:1971-03-05
Applicant: BASF AG
Inventor: REICHENEDER FRANZ DR , WUNSCH GERD DR , BEWERT WOLFGANG DR , ADOLPHI HEINRICH DR
IPC: A01N57/16 , C07F9/6509
Abstract: Cpds. of formula (I): (where X is halogen or alkoxy Y = O or S; R2 and R3 are 1 - 6C alkyl opt. substd. by halogen, or R2 + R3 is ethylene) are insecticides esp. active against adult and larval forms of diptera. Preferred are (I) where X = MeO, R2 = R3 = Et and Y = O or S. (I; Y = O) may be prepd. by reacting (II) with (III): (where W = halogen; R4 = alkyl). Cpds. (I) can also be prepd. by reacting an enol or alkali metal enolate of 1-Ph-5-X-pyridazine-4(5H), 6(1H)-dione with Cl(Y)P(OR2)OR3 in an inert solvent in the presence of an acid binder.
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公开(公告)号:ES2151890T3
公开(公告)日:2001-01-16
申请号:ES93108769
申请日:1993-06-01
Applicant: BASF AG
Inventor: KIEFER HANS DR , BETZ ROLAND DR , BEWERT WOLFGANG DR
IPC: A23K1/16 , A23K20/174 , A23K40/10 , A23L1/00 , A23P1/02 , A23P1/04 , A23P1/06 , A23P10/30 , B01J2/16 , B01J2/30 , C07C213/10 , C07C215/40
Abstract: Process for producing dry, free-flowing, choline chloride-containing powders by atomising an aqueous choline chloride solution, a colloid-free aqueous choline chloride solution being atomised in a counter-current airstream which contains, finely dispersed, a hydrophobic spraying aid added in amounts such that the sprayed choline chloride droplets are coated with 2 to 15% by weight, based on choline chloride calculated as 100%, and the coated particles, if required, are collected in a fluid bed and dried in the gas stream.
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公开(公告)号:DK0547422T3
公开(公告)日:1996-04-01
申请号:DK92120456
申请日:1992-12-01
Applicant: BASF AG
Inventor: SCHNEIDER JOACHIM U DR , RHEUDE UDO DR , BEWERT WOLFGANG DR , SCHUMACHER HORST DR , GAUS GUENTER DR
Abstract: Process for the production of stable dry powders which are insoluble in hot water and which contain fat-soluble vitamins and/or carotenoids, which comprises the following process steps: a) preparation of an aqueous dispersion containing essentially these fat-soluble active substances, film-forming colloids and reducing sugars, b)conversion of this dispersion into dry powders of vitamin and/or carotenoid products and c) thermal hardening of the powder at temperatures of 60 to 180 DEG C, and which is characterised in that gelatin in combination with one or more organic amino compounds which are free or bound as salts and which contain a basic primary amino group and additionally either another amino group, a hydroxyl group, an alkoxy group or a carboxyl group, and/or in combination with sufficient basic alkali metal or alkaline earth metal compound for the dispersion to have a pH of 7.5 to 10, is used as film-forming colloid, and the dry powders obtainable by this process are described.
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公开(公告)号:DE4218768A1
公开(公告)日:1993-12-09
申请号:DE4218768
申请日:1992-06-06
Applicant: BASF AG
Inventor: KIEFER HANS DR , BETZ ROLAND DR , BEWERT WOLFGANG DR
IPC: A23K1/16 , A23K20/174 , A23K40/10 , A23L1/00 , A23P1/02 , A23P1/04 , A23P1/06 , A23P10/30 , B01J2/16 , B01J2/30 , C07C213/10 , C07C215/40 , C07C215/90
Abstract: Process for producing dry, free-flowing, choline chloride-containing powders by atomising an aqueous choline chloride solution, a colloid-free aqueous choline chloride solution being atomised in a counter-current airstream which contains, finely dispersed, a hydrophobic spraying aid added in amounts such that the sprayed choline chloride droplets are coated with 2 to 15% by weight, based on choline chloride calculated as 100%, and the coated particles, if required, are collected in a fluid bed and dried in the gas stream.
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