公开(公告)号：BR0007060A

公开(公告)日：2001-07-31

申请号：BR0007060

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： MULLER MATTHEW R ,  JOIE MICHEL L T ,  VANDLIK MARK R

IPC: G01N33/483 ,  A61M1/02 ,  A61M1/36 ,  A61M1/38 ,  B01D17/02 ,  B01D17/12 ,  B01D21/24 ,  B04B5/00 ,  G01N21/05 ,  G01N21/07 ,  G01N21/35 ,  G01N33/49

公开(公告)号：NO20012172D0

公开(公告)日：2001-05-02

申请号：NO20012172

申请日：2001-05-02

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VISHNOI ROHIT ,  VANDLIK MARK R

IPC: A61M1/10 ,  A61M1/02 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  F04B13/02 ,  F04B43/02 ,  F04B49/06 ,  A61M

Abstract: Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

公开(公告)号：CA2347537A1

公开(公告)日：2001-03-15

申请号：CA2347537

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VISHNOI ROHIT ,  VANDLIK MARK R

IPC: F04B9/123 ,  A61B5/15 ,  A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  F04B13/02 ,  F04B43/02 ,  F04B43/06 ,  F04B49/06 ,  F04B49/00

Abstract: Programmable, fluid pressure actuated blood processing systems (10) and methods are used in association with a blood separation device (18). The systems and methods employ a cassette (28), which contains several preformed , pneumatically actuated pump stations (PP1-PP4), several preformed fluid flow paths (F1-F38), and several preformed, pneumatically actuated (VA1-VA23) valves (1-23) in the fluid flow paths. The systems and methods also employ progr ammable pneumatic actuators (PA1-PA4) to hold the cassette and selectively apply pneumatic force to the valves and the pump stations.

公开(公告)号：CA2346906A1

公开(公告)日：2001-03-15

申请号：CA2346906

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： JOIE MICHEL L T ,  VANDLIK MARK R ,  MULLER MATTHEW R

IPC: G01N33/483 ,  A61M1/02 ,  A61M1/36 ,  A61M1/38 ,  B01D17/02 ,  B01D17/12 ,  B01D21/24 ,  B04B5/00 ,  G01N21/05 ,  G01N21/07 ,  G01N21/35 ,  G01N33/49

Abstract: Red blood cell sensing systems rely upon straightforward measurement geometries. The systems are based around a sensing station (332) having incident light source containing optical sensor s (334) and (336) and blood collection tubes (290), (292) and (294). The systems hold the blood collection tubes (290), (292) and (294 ) a predetermined radial distance from the sensors (334) and (336), where a linear relationship exists between sensed reflected light measured by the sensor; (334) and (336) and red blood cell hematocrit in a range of at least 10 to 90. The systems make possible accurate red blood sensing without use of special optical cuvettes, mirrors, or focusing lenses. The systems also make possible the us e of standard transparent plastic tubing, without reliance upon special optical cuvettes.

公开(公告)号：DE60239476D1

公开(公告)日：2011-04-28

申请号：DE60239476

申请日：2002-10-02

Applicant: BAXTER INT

Inventor： VANDLIK MARK R ,  KAST MICHAEL J ,  SMITH KELLY B

IPC: A61M1/02 ,  A61M37/00 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36

公开(公告)号：CA2347130C

公开(公告)日：2009-03-17

申请号：CA2347130

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VANDLIK MARK R ,  VISHNOI ROHIT

IPC: A61M1/02 ,  A61M1/38 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  F04B9/08 ,  F04B17/00 ,  F04B35/00 ,  F04B49/00

Abstract: A multiple function pump station (PPN) performs different on-line processing tasks. The pump station can be oper-ated in one mode to draw blood from a donor and can in another mode be operated t o return blood to the donor. The pump station used to draw blood from a donor can also be used to perform subsequent blood processing tasks, such as mixing processing or additive fluids with the blood, or transferring a harvested blood component to a storage container, or finishing the processing of a harvested blood component, e.g., by passage through a filter (200) to remove leukocyte s.

公开(公告)号：CA2347537C

公开(公告)日：2009-01-20

申请号：CA2347537

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： VANDLIK MARK R ,  WESTBERG TOM ,  VISHNOI ROHIT

IPC: F04B9/123 ,  F04B49/00 ,  A61B5/15 ,  A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  F04B13/02 ,  F04B43/02 ,  F04B43/06 ,  F04B49/06

Abstract: Programmable, fluid pressure actuated blood processing systems (10) and methods are used in association with a blood separation device (18). The systems and methods employ a cassette (28), which contains several preformed, pneumatically actuated pump stations (PP1-PP4), several preformed fluid flow paths (F1-F38), and several preformed, pneumatically actuated (VA1-VA23) valves (1-23) in the fluid flow paths. The systems and methods also employ progr ammable pneumatic actuators (PA1-PA4) to hold the cassette and selectively apply pneumatic force to the valves and the pump stations.

公开(公告)号：AU775593B2

公开(公告)日：2004-08-05

申请号：AU7335800

申请日：2000-08-29

Applicant: BAXTER INT

Inventor： WESTBERG TOM ,  VISHNOI ROHIT ,  VANDLIK MARK R

IPC: A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  F04B13/02 ,  F04B43/02 ,  F04B49/06 ,  B01D37/00 ,  B01D61/00 ,  B01D63/00 ,  C02F1/00 ,  C02F1/44 ,  F04B9/08 ,  F04B17/00 ,  F04B35/00 ,  F04B49/00

Abstract: Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

公开(公告)号：BR0206144A

公开(公告)日：2004-02-17

申请号：BR0206144

申请日：2002-10-02

Applicant: BAXTER INT

Inventor： VANDLIK MARK R ,  KAST MICHAEL J ,  SMITH KELLY B

IPC: A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  C02F1/00 ,  B01D33/15

Abstract: Systems and methods separate pump the blood cells through an in-line leukofilter to a blood cell storage container. The leukofilter has a filtration medium enclosed within a flexile housing. The systems and methods can employ a fixture to restrain expansion of the flexible filter housing during operation of the pump.

公开(公告)号：NO20012171L

公开(公告)日：2001-06-26

申请号：NO20012171

申请日：2001-05-02

Applicant: BAXTER INT

Inventor： VISHNOI ROHIT ,  WESTBERG TOM ,  MULLER MATTHEW R ,  SMITH KELLY B ,  JOIE MICHEL L F ,  VANDLIK MARK R

IPC: A61M1/02 ,  G01N33/48 ,  A61M1/34 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B04B5/00 ,  G01N21/27 ,  G01N21/35 ,  G01N33/483 ,  G01N33/49 ,  A61M1/38 ,  B01D21/26

Abstract: A blood separation system (10) is described. The system comprises a device (14, 18) which, in use, operates to separate whole blood into red blood cells and plasma, a whole blood inlet line (290) for conveying a flow of whole blood into the device, a plasma collection line (292) for conveying a flow of plasma from the device, and a red blood cell collection line (294) for conveying a flow of red blood cells from the device. A first sensing assembly (334) including a first sensor in the plasma collection line is provided which in use operates to detect a characteristic of plasma in the flow of plasma and to generate a first output. A second sensing assembly (336) including a second sensor in the red blood cell collection line is provided which in use operates to detect a characteristic of red blood cells in the flow of red blood cells and to generate a second output. A controller (16) operates to control flows in the plasma collection line and the red blood cell collection line based upon the first and second outputs.