公开(公告)号：AU9165191A

公开(公告)日：1992-07-22

申请号：AU9165191

申请日：1991-12-20

Applicant: BAXTER INT

Inventor： BISCHOF DANIEL F ,  WOLF LUDWIG JR ,  FOLEY JOHN T ,  BRATTEN WILLIAM R

IPC: A61M1/36 ,  A61L2/00 ,  A61L2/08 ,  A61M1/34 ,  B01J19/12 ,  A61M37/00

Abstract: A system and method for treating a fluid carrying a biological contaminant to which a photoactive material has been bound include a treatment device that defines a flow passage with a gap. The system and method operate to establish a flow of fluid from the inlet end of the gap to the outlet end of the gap. The system and method expose the fluid, as it transits the gap, to a source of radiation that activates the photoactive material bound to the contaminant. The system and method also mix the fluid as it flows within the gap.

公开(公告)号：CA2075640A1

公开(公告)日：1992-06-21

申请号：CA2075640

申请日：1991-12-20

Applicant: BAXTER INT ,  QUADRA LOGIC TECHNOLOGIES

Inventor： WOLF LUDWIG JR ,  FOLEY JOHN T ,  BRATTEN WILLIAM R ,  KUNZ GARY ,  STONEFIELD MICHAEL

IPC: A61L2/00 ,  A61L2/08 ,  A61L2/10 ,  A61M1/36 ,  B01J19/12

Abstract: A system (10) and method for treating a fluid carrying a contaminant to which a photoactive material has been bound include a treatment device (12) that defines a flow passage (36) with a dap (28). The system and method operate to establish a flow of fluid from the inlet (38) end of the gap (28) to the outlet end (40) of the, gap (28). The system and method also channel he flow of fluid in the gap (28) in succession through one or more paths. The system and method esta- blished at least two discrete sources of ra- diation (30), in the flow path (36) at spaced, apart locations along the direc- lion of fluid flow. At least one of the ra- diation sources (30) comprises a photodi- ode. The system and method further in- clude a control far operating each dis- crete source of radiation at a selected wavelength within the prescribed range to activate the photoactive material bound to the contaminant. Upon activa- tion, the material eradicates the contami- nant. The system and method provide ex- tracorporeal treatment of fluids like blood to quickly and effectively eradicate infection agents at relatively high flow rates.