Abstract:
A flexible, three-dimensional container (10) is made by a prescribed vacuum-molding and heat sealing process. The container (10) possesses a precise, defined geometry before and during use. The container (10) is formed from first and second walls. The first wall has a planar area and a vacuum-molded cavity area drawn out of the plane of the planar area into a predefined three-dimensional geometry. A second wall overlies the first wall to close the cavity area and thereby forms an interior compartment (12, 14). A thermal seal joins the two walls together. The seal (28) is formed by heating the second wall and the first wall in the planar area, while assuring that the cavity area of the first wall is not subject to heating and possible deformation of its precise vacuum-molded geometry.
Abstract:
A method for treating a body fluid to at least substantially inactivate viral contaminants that may be present therein comprising the steps of: providing a body fluid; adding to the body fluid a viral inactivating agent to create a resultant product; and passing the resultant product through a column including material having an affinity for the viral inactivating agent.
Abstract:
A method and apparatus for virally inactivating a body fluid wherein a mixtu re including a therapeutically effective amount of methylene blue and an amount of a body fluid is formed in a container under sterile conditions and then the container is irradiated with a light field of a suitable intensity and wavelength for activating the methylene blue for a time sufficient to inactivate viruses in the mixture, while maintaining the mixture in a substantially static state within the container.
Abstract:
Assemblies and methods process cord blood in a sterile fashion to avoid exposure to bacterial contamination. A transfer tube couples a cord blood processing container to an other container, which, in use, holds a cryopreservative solution. The transfer tube has an interior diameter that is restricted substantially along its entire length, to meter the introduction of cryopreservation solution into cord blood at a desired rate, thereby avoiding damage or trauma to the cord blood cells.
Abstract:
A method for treating a body fluid to at least substantially inactivate viral contaminants that may be present therein is provided. The method includes the steps of: providing a body fluid; adding to the body fluid a viral inactivating agent to create a resultant product; and passing the resultant product through a column including material having an affinity for the viral inactivating agent.
Abstract:
A system and method for treating a fluid carrying a biological contaminant to which a photoactive material has been bound include a treatment device that defines a flow passage with a gap. The system and method operate to establish a flow of fluid from the inlet end of the gap to the outlet end of the gap. The system and method expose the fluid, as it transits the gap, to a source of radiation that activates the photoactive material bound to the contaminant. The system and method also mix the fluid as it flows within the gap.
Abstract:
2075704 9211058 PCTABS00014 A system and method for treating a fluid carrying a biological contaminant to which a photoactive material has been bound include a treatment device (20) that defines a flow passage with a gap (26). The system and method operate to establish a flow of fluid from the inlet end (68) of the gap (26) to the outlet end (70) of the gap (26). The system and method expose the fluid, as it transits the gap (26) to a source of radiation (52) that activates the photoactive material bound to the contaminant. The system and method also mix the fluid as it flows within the gap (26).