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公开(公告)号：CL2018001493A1
公开(公告)日：2018-09-14
申请号：CL2018001493
申请日：2018-06-04
Applicant: HOFFMANN LA ROCHE
Inventor： ROGERS-EVANS MARK , GAVELLE OLIVIER , GRETHER UWE , NETTEKOVEN MATTHIAS , ROEVER STEPHAN , ROMBACH DIDIER
IPC: C07C13/04 , C07D205/04 , C07D209/54 , C07D231/12 , C07D277/30 , C07D331/04 , C07D401/10 , C07D413/06 , C07D413/10 , C07D413/12
Abstract: LA INVENCIÓN SE REFIERE A UN COMPUESTO DE LA FÓRMULA (I), EN LA QUE DE R1 A R3 TIENEN LOS SIGNIFICADOS DEFINIDOS EN LA DESCRIPCIÓN Y EN LAS REIVINDICACIONES. EL COMPUESTO DE LA FÓRMULA (I) PUEDE EMPLEARSE COMO MEDICAMENTO.
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公开(公告)号：CO2018004573A2
公开(公告)日：2018-06-12
申请号：CO2018004573
申请日：2018-04-27
Applicant: HOFFMANN LA ROCHE
Inventor： NETTEKOVEN MATTHIAS , ROEVER STEPHAN , ROGERS-EVANS MARK , GAVELLE OLIVIER , GRETHER UWE , ROMBACH DIDIER
IPC: C07D231/12 , A61K31/4245 , A61P29/00 , C07C13/04 , C07D205/04 , C07D207/14 , C07D209/54 , C07D213/61 , C07D271/06 , C07D277/30 , C07D305/06 , C07D331/04 , C07D401/10 , C07D403/10 , C07D413/06 , C07D413/10 , C07D413/12
Abstract: La invención se refiere a un compuesto de la fórmula (I), en la que de R1 a R3 tienen los significados definidos en la descripción y en las reivindicaciones. El compuesto de la fórmula (I) puede emplearse como medicamento.
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公开(公告)号：LT2978755T
公开(公告)日：2018-03-12
申请号：LT14712287
申请日：2014-03-24
Applicant: HOFFMANN LA ROCHE
Inventor： GAVELLE OLIVIER , GRETHER UWE , KIMBARA ATSUSHI , NETTEKOVEN MATTHIAS , ROEVER STEPHAN , ROGERS-EVANS MARK , ROMBACH DIDIER , SCHULZ-GASCH TANJA
IPC: C07D401/04 , C07D401/14 , C07D403/04 , C07D413/04 , C07D413/14 , C07D491/107
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公开(公告)号：AU2013354113B2
公开(公告)日：2018-03-08
申请号：AU2013354113
申请日：2013-12-04
Applicant: HOFFMANN LA ROCHE
Inventor： GRETHER UWE , KIMBARA ATSUSHI , NETTEKOVEN MATTHIAS , RICKLIN FABIENNE , ROEVER STEPHAN , ROGERS-EVANS MARK , ROMBACH DIDIER , SCHULZ-GASCH TANJA , WESTPHAL MATTHIAS
IPC: C07D213/81 , A61K31/444 , A61P29/00 , C07D401/06 , C07D401/12 , C07D405/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D491/10
Abstract: The invention relates to a compound of formula (I) wherein R
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公开(公告)号：UA116239C2
公开(公告)日：2018-02-26
申请号：UAA201510076
申请日：2014-03-24
Applicant: HOFFMANN LA ROCHE
Inventor： GAVELLE OLIVIER , GRETHER UWE , KIMBARA ATSUSHI , NETTEKOVEN MATTHIAS , ROEVER STEPHAN , ROGERS-EVANS MARK , ROMBACH DIDIER , SCHULZ-GASCH TANJA
IPC: A61K31/422 , C07D413/14 , A61K31/4245 , C07D403/04 , C07D413/04
Abstract: Данийвинахідстосуєтьсясполукиформули (І) EMBED ISISServer , (I) деА і R1-R4 визначенів описіі уформулівинаходу. Сполукуформули (І) можназастосовуватияклікарськийзасіб.
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Patent Agency Ranking
公开(公告)号：DK2928867T3
公开(公告)日：2017-10-23
申请号：DK13799543
申请日：2013-12-04
Applicant: HOFFMANN LA ROCHE
Inventor： GRETHER UWE , KIMBARA ATSUSHI , NETTEKOVEN MATTHIAS , RICKLIN FABIENNE , ROEVER STEPHAN , ROGERS-EVANS MARK , ROMBACH DIDIER , SCHULZ-GASCH TANJA , WESTPHAL MATTHIAS
IPC: C07D213/81 , A61K31/444 , A61P29/00 , C07D401/06 , C07D401/12 , C07D405/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D491/10
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公开(公告)号：CA2999216A1
公开(公告)日：2017-06-15
申请号：CA2999216
申请日：2016-12-06
Applicant: HOFFMANN LA ROCHE
Inventor： GAVELLE OLIVIER , GRETHER UWE , NETTEKOVEN MATTHIAS , ROEVER STEPHAN , ROGERS-EVANS MARK , ROMBACH DIDIER
IPC: C07D231/12 , A61K31/4245 , A61P29/00 , C07C13/04 , C07D205/04 , C07D207/14 , C07D209/54 , C07D213/61 , C07D271/06 , C07D277/30 , C07D305/06 , C07D331/04 , C07D401/10 , C07D403/10 , C07D413/06 , C07D413/10 , C07D413/12
Abstract: The invention relates to a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
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公开(公告)号：ZA201503600B
公开(公告)日：2016-01-27
申请号：ZA201503600
申请日：2015-05-21
Applicant: HOFFMANN LA ROCHE
Inventor： ROEVER STEPHAN , NETTEKOVEN MATTHIAS , GRETHER UWE , ROMBACH DIDIER , RICKLIN FABIENNE , WESTPHAL MATTHIAS , SCHULZ-GASCH TANJA , ROGERS-EVANS MARK , KIMBARA ATSUSHI
Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) is a CB2 agonist and can be used as an active ingredient in a medicament.
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公开(公告)号：PH12015501082B1
公开(公告)日：2015-08-03
申请号：PH12015501082
申请日：2015-05-15
Applicant: F HOFFMANN - LA ROCHE AG
Inventor： GRETHER UWE , KIMBARA ATSUSHI , NETTEKOVEN MATTHIAS , RICKLIN FABIENNE , ROEVER STEPHAN , ROGERS-EVANS MARK , ROMBACH DIDIER , SCHULZ-GASCH TANJA , WESTPHAL MATTHIAS
IPC: A61K31/444 , A61P29/00 , C07D213/81 , C07D401/06 , C07D401/12 , C07D405/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D491/10
Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) is a CB2 agonist and can be used as an active ingredient in a medicament.
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公开(公告)号：CA2890353A1
公开(公告)日：2014-06-12
申请号：CA2890353
申请日：2013-12-04
Applicant: HOFFMANN LA ROCHE
Inventor： GRETHER UWE , KIMBARA ATSUSHI , NETTEKOVEN MATTHIAS , RICKLIN FABIENNE , ROEVER STEPHAN , ROGERS-EVANS MARK , ROMBACH DIDIER , SCHULZ-GASCH TANJA , WESTPHAL MATTHIAS
IPC: C07D213/81 , A61K31/444 , A61P29/00 , C07D401/06 , C07D401/12 , C07D405/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D491/10
Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) is a CB2 agonist and can be used as an active ingredient in a medicament.
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