公开(公告)号：AU497296B2

公开(公告)日：1978-12-07

申请号：AU2692977

申请日：1977-07-11

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  TSUSHIMA SUSUMU

IPC: C07H15/23 ,  C07H15/22 ,  A61K31/71

公开(公告)号：DE2727753A1

公开(公告)日：1978-03-16

申请号：DE2727753

申请日：1977-06-21

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  TSUSHIMA SUSUMU

IPC: A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D257/04 ,  C07D277/38 ,  C07D277/40 ,  C07D277/46 ,  C07D499/00 ,  C07D501/00 ,  C07D501/20 ,  C07D501/22 ,  C07D501/24 ,  C07D501/28 ,  C07D501/34 ,  C07D501/36 ,  C07D501/38 ,  C07D501/46 ,  C07D501/56 ,  C07D501/60

Abstract: Disclosed are 2-(syn)-hydroxyimino-acetamide derivatives of the formula: wherein Y is hydrogen, hydroxyl, an acyloxy, carbamoyloxy, a quaternary ammonium or a nitrogen-containing heterocyclic ring-substituted thio group; or pharmaceutically acceptable salts or esters thereof are useful as antibacterial agents. Also disclosed are processes for producing them.

公开(公告)号：AU2692977A

公开(公告)日：1977-10-06

申请号：AU2692977

申请日：1977-07-11

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  TSUSHIMA SUSUMU

IPC: C07H15/23 ,  C07H15/22 ,  A61K31/71

公开(公告)号：AU7412474A

公开(公告)日：1976-04-15

申请号：AU7412474

申请日：1974-10-09

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： IMASHIRO YOSHIO ,  MINAMIDA ISAO ,  NUMATA MITSUO ,  YAMAOKA MASAYOSHI

IPC: C07D501/06 ,  A61K31/43 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D501/20 ,  C07D501/22 ,  C07D501/24 ,  C07D501/26 ,  C07D501/28 ,  C07D501/36 ,  C07D501/60 ,  A61K27/00 ,  C07D99/24

Abstract: Novel compounds of the formula: wherein X is a lower alkanoyloxy group or a substituted thio group, where the substituent is a nitrogen-containing heterocyclic group, or a pharmaceutically acceptable salt or ester thereof, have a broad antimicrobial spectrum, and besides they are readily absorbed into the living body. Thus, the compounds are useful as therapeutic agent for various bacterial infections of animals including human beings.

公开(公告)号：CA842827A

公开(公告)日：1970-05-26

申请号：CA842827D

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  SHIMAHARA NOBORU ,  KAWAI KIYOHISA ,  HIRANO HIROSHI

公开(公告)号：CA1316171C

公开(公告)日：1993-04-13

申请号：CA280699

申请日：1977-06-16

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  TSUSHIMA SUSUMU

IPC: A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D257/04 ,  C07D277/38 ,  C07D277/40 ,  C07D277/46 ,  C07D499/00 ,  C07D501/00 ,  C07D501/20 ,  C07D501/22 ,  C07D501/24 ,  C07D501/28 ,  C07D501/34 ,  C07D501/36 ,  C07D501/38 ,  C07D501/46 ,  C07D501/56 ,  C07D501/60

Abstract: NOVEL CEPHALOSPORIN DERIVATIVES of the disclosure A 2-(syn)-hydroxyimino-acetamide derivative of the formula; wherein Y is hydrogen, hydroxyl, an acyloxy, carbamoyloxy, a quaternary ammonium or a nitrogen-containing heterocyclic ring-substituted thio group; or pharmaceutieally acceptable salts or esters thereof are useful as antibacterial agent.

公开(公告)号：DK161081B

公开(公告)日：1991-05-27

申请号：DK621189

申请日：1989-12-08

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  TSUSHIMA SUSUMU

IPC: A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D257/04 ,  C07D277/38 ,  C07D277/40 ,  C07D277/46 ,  C07D499/00 ,  C07D501/00 ,  C07D501/20 ,  C07D501/22 ,  C07D501/24 ,  C07D501/28 ,  C07D501/34 ,  C07D501/36 ,  C07D501/38 ,  C07D501/46 ,  C07D501/56 ,  C07D501/60

Abstract: Disclosed are 2-(syn)-hydroxyimino-acetamide derivatives of the formula: wherein Y is hydrogen, hydroxyl, an acyloxy, carbamoyloxy, a quaternary ammonium or a nitrogen-containing heterocyclic ring-substituted thio group; or pharmaceutically acceptable salts or esters thereof are useful as antibacterial agents. Also disclosed are processes for producing them.

公开(公告)号：SU1586518A3

公开(公告)日：1990-08-15

申请号：SU4028149

申请日：1986-09-16

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NISIMURA TATSUO ,  ESIMURA ESINOBU ,  NUMATA MITSUO

IPC: C07D501/36 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D501/20 ,  C07D501/34 ,  C07D501/46

公开(公告)号：DK621189D0

公开(公告)日：1989-12-08

申请号：DK621189

申请日：1989-12-08

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NUMATA MITSUO ,  MINAMIDA ISAO ,  TSUSHIMA SUSUMU

IPC: A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D257/04 ,  C07D277/38 ,  C07D277/40 ,  C07D277/46 ,  C07D499/00 ,  C07D501/00 ,  C07D501/20 ,  C07D501/22 ,  C07D501/24 ,  C07D501/28 ,  C07D501/34 ,  C07D501/36 ,  C07D501/38 ,  C07D501/46 ,  C07D501/56 ,  C07D501/60

Abstract: Disclosed are 2-(syn)-hydroxyimino-acetamide derivatives of the formula: wherein Y is hydrogen, hydroxyl, an acyloxy, carbamoyloxy, a quaternary ammonium or a nitrogen-containing heterocyclic ring-substituted thio group; or pharmaceutically acceptable salts or esters thereof are useful as antibacterial agents. Also disclosed are processes for producing them.

公开(公告)号：SU1512483A3

公开(公告)日：1989-09-30

申请号：SU4202807

申请日：1987-06-25

Applicant: TAKEDA CHEMICAL INDUSTRIES LTD

Inventor： NISIMURA TATSUO ,  ESIMURA ESINOVU ,  NUMATA MITSUO

IPC: C07D501/36 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D501/20 ,  C07D501/34 ,  C07D501/46