Abstract:
Disclosed is a membrane material comprising a hydrophobic polymer and a hydrophilic polymer. The hydrophilic polymer consists of 10-50 wt. % of a low molecular weight component having a molecular weight of less than 100,000 and 90-50 wt. % of a high molecular weight component having a molecular weight of at least 100,000. The membrane material may be subjected to an insolubilization treatment to provide a permselective membrane suitable for use in dialysis. The membrane material may have an overall mass transfer coefficient (Ko), for a Stokes' radius of at least 30 .ANG. (as determined by a diffusion test using dextran), of at least 0.0025 cm/min and a permeability to albumin of at most 4 %.
Abstract:
An antithrombotic blood treating system comprising a combination of a permselective hollow fiber membrane containing a copolymer having a polyethylene oxide unit; a header having a blood-contacting surface coated with either a heparinized hydrophilic copolymer containing vinyl chloride as the constituent or a hydrophilic copolymer having a polyethylene oxide unit; a catheter; and a circuit. It becomes possible for the first time to conduct extracorporeal circulation for a long period of time without the necessity for internally administering heparin by imparting an antithrombotic property to the entire blood-contacting surface.
Abstract:
An antithrombotic blood treating system comprising a combination of a permselective hollow fiber membrane containing a copolymer having a polyethylene oxide unit; a header having a blood-contacting surface coated with either a heparinized hydrophilic copolymer containing vinyl chloride as the constituent or a hydrophilic copolymer having a polyethylene oxide unit; a catheter; and a circuit. It becomes possible for the first time to conduct extracorporeal circulation for a long period of time without the necessity for internally administering heparin by imparting an antithrombotic property to the entire blood-contacting surface.
Abstract:
An antithrombotic blood treating system comprising a combination of a permselective hollow fiber membrane containing a copolymer having a polyethylene oxide unit; a header having a blood-contacting surface coated with either a heparinized hydrophilic copolymer containing vinyl chloride as the constituent or a hydrophilic copolymer having a polyethylene oxide unit; a catheter; and a circuit. It becomes possible for the first time to conduct extracorporeal circulation for a long period of time without the necessity for internally administering heparin by imparting an antithrombotic property to the entire blood-contacting surface.
Abstract:
Disclosed is a hydrophilic material characterized in that the material comprises a copolymer composed of a monomer (A) having a polyalkylene oxide unit and a polymerizable carboncarbon double bond in its molecule, a methacrylic ester monomer or an acrylic ester monomer (B) and a monomer (C) having a polymerizable carbon-carbon double bond other than the monomers (A) and (B), and the content of the monomer (C) is not less than 5% by weight and not more than 90% by weight, and a semipermeable membrane made therefrom. The present invention provides a hydrophilic material which can be dissolved in a solvent, can be easily formed and is excellent in antithrombotic and antifouling properties, and further provides an antithrombotic material and a semipermeable membrane. These materials can be appropriately used in the medical field and as water-absorbent and antifouling materials. - 4 6
Abstract:
There are provided porous fibers having excellent removal performance with respect to a material to be purified; and a purification column into which an adsorbent material obtained by bundling the fibers is incorporated. The porous fibers satisfying the following conditions (a) and (b) and having a shape in which three or more projected parts are continuously present in the lengthwise direction on the periphery part of a solid-state fiber: (a) The modification degree Do/Di in a cross section is 1.2 to 6.6 when the diameter of the inscribed circle is denoted by Di and the diameter of the circumscribed circle is denoted by Do., and (b) The specific surface area of pores is 50 m 2 /g or more.
Abstract:
The present invention aims to provide a purification column having excellent performance to remove substances to be removed. Further, the present invention aims to provide a method for producing the purification column described above. The above object can be achieved with a purification column comprising a cylindrical casing having partition walls formed at both side ends, the casing containing therein hollow fibers whose both ends are fixed by bonding to the partition walls such that the both ends open to the outside of the partition walls, wherein penetrating holes that penetrate the partition walls to communicate with the inside and outside of the casing are formed in the partition walls at both ends of the casing.
Abstract:
The present invention relates to a filter built into a blood purification column, and aims to dramatically improve the removal of air that gets into the column and to prevent blood activation due to air remaining inside of the column and decreased adsorption performance due to decreased contact surface between blood and an adsorbent. This blood purification column has an adsorbent and a casing, both ends of which are open ends, and the adsorbent is housed inside of the casing. Of the two ends of the casing, one is the blood inflow end and the other is the blood outflow end. A filter is arranged on the blood inflow end and/or the blood outflow end of the casing, and this filter fulfils the following conditions. (1) The opening ratio of the filter is 5-80% (2) The equivalent diameter of the openings in the filter is 1-5000µm (3) The ratio of the equivalent diameter of the openings to the average circle equivalent diameter of the gaps in the absorbent is 45% or greater.
Abstract:
The invention provides a water vapor permeable membrane comprising a dense layer and a support layer that are adjacent to each other, wherein said dense layer contains voids with a void length of 0.1 µm or less and said layer has a thickness of 0.1 µm or more and 2 µm or less while in said support layer, void (a), i.e. the void with the largest length in the 2 µm thick region measured from the boundary between the dense layer and the support layer into the support layer, has a length of 0.3 µm or more and void (b), i.e. the void with the largest length in the region ranging between 2 µm and 4 µm measured from said boundary into the support layer, has a length of 0.5 µm or more, the length of said void (b) being larger than that of said void (a). The invention provides a water vapor permeable membrane having both a high water vapor permeability and a low air leakage.