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公开(公告)号：CA2607197C
公开(公告)日：2016-12-13
申请号：CA2607197
申请日：2006-04-28
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
IPC: C07K16/22 , A61K39/395 , C07K14/475 , C07K14/51 , C07K16/18 , C12N15/13 , C12P21/08
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
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公开(公告)号：CR20140081A
公开(公告)日：2014-03-25
申请号：CR20140081
申请日：2014-02-19
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON
IPC: C07K14/51
Abstract: Se brindan composiciones y métodos relacionados a epitopos de la proteína esclerostinay los agentes de fijación de esclerostina, tales como anticuerpos capaces de fijarse a la esclerostina.
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公开(公告)号：AU2013205486A1
公开(公告)日：2013-05-16
申请号：AU2013205486
申请日：2013-04-12
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： WINTERS AARON GEORGE , LAWSON ALASTAIR , HENRY ALISTAIR JAMES , POPPLEWELL ANDY , PASZTY CHRISTOPHER , SHEN WENYAN , LU HSIENG SEN , LATHAM JOHN , HOFFMANN KELLY SUE , GRAHAM KEVIN , ROBINSON MARTYN KIM , WINKLER DAVID
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. '13A ZC j ~4v oddoocooo LO) cc) m 0. E %*L> z & I .0 1'
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公开(公告)号：UA98927C2
公开(公告)日：2012-07-10
申请号：UAA200713404
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
IPC: C07K14/51 , A61K39/395 , C07K16/18 , C07K16/46 , C12N15/13
Abstract: Изобретениеотноситсяк антителу, котороеспецифичносвязываетсклеростин, ифармацевтическойкомпозиции, котораяегосодержит.
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公开(公告)号：TNSN07406A1
公开(公告)日：2009-03-17
申请号：TNSN07406
申请日：2007-10-31
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
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Patent Agency Ranking
公开(公告)号：RS62685B1
公开(公告)日：2021-12-31
申请号：RSP20211488
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
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公开(公告)号：UA123695C2
公开(公告)日：2021-05-19
申请号：UAA201202580
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Винахідналежитьдополіпептиду, щоявляєсобоюепітопбілкасклеростинулюдини, способуодержанняантитіла, якезв’язуєвказанийепітоп, антитіла, здатногозв'язуватисяізвказанимепітопомсклеростину, виділеногополінуклеотиду, клонуючогоабоекспресуючоговектора, клітини-хазяїна, фармацевтичноїкомпозиції, застосуванняфармацевтичноїкомпозиціїдлялікуванняпорушення, опосередкованогопідвищенимрівнемсклеростинутадіагностичногонабору, щоміститьзазначенеантитіло.
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公开(公告)号：ES2689143T3
公开(公告)日：2018-11-08
申请号：ES10008795
申请日：2006-04-28
Applicant: UCB PHARMA SA
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTY KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: Un anticuerpo de unión a esclerostina que comprende las siguientes secuencias de CDR: CDR-H1: DYIMH (SEQ ID NO: 269); CDR-H2: YINPYNDDTEYNEKFKG (SEQ ID NO: 270); CDR-H3: SIYYYDAPFAY (SEQ ID NO: 271); CDR-L1: RASQDISSYLN (SEC ID No: 239); CDR-L2: STSRLNS (SEQ ID NO: 240); y CDR-L3: QQDIKHPT (SEQ ID NO: 241).
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公开(公告)号：AU2012238247B2
公开(公告)日：2016-06-16
申请号：AU2012238247
申请日：2012-10-08
Applicant: AMGEN INC , UCB PHARMA SA
Inventor： WINTERS AARON GEORGE , LAWSON ALASTAIR , HENRY ALISTAIR JAMES , POPPLEWELL ANDY , PASZTY CHRISTOPHER , SHEN WENYAN , LU HSIENG SEN , LATHAM JOHN , HOFFMANN KELLY SUE , GRAHAM KEVIN , ROBINSON MARTYN KIM , WINKLER DAVID
Abstract: C:\NRPorbl\DCCSZPWA6573 I DOC.4/10/2012 Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. 4v Lu L % 6 Iii cc ~ O O. . .U te,, Lo~ .CD C; L 0ZDB aweI
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公开(公告)号：GEP20166454B
公开(公告)日：2016-04-11
申请号：GEAP2006012335
申请日：2006-04-28
Applicant: UCB PHARMA SA , AMGEN INC
Inventor： PASZTY CHRISTOPHER , ROBINSON MARTYN KIM , GRAHAM KEVIN , HENRY ALISTAIR JAMES , HOFFMANN KELLY SUE , LATHAM JOHN , LAWSON ALASTAIR , LU HSIENG SEN , POPPLEWELL ANDY , SHEN WENYAN , WINKLER DAVID , WINTERS AARON GEORGE
Abstract: An invention relates to antibodies binding sclerostin epitopes, which crossly block Ab-C, Ab-D, Ab-13 or Ab-14 binding with sclerostin sequ¬ences SEQ ID NO: 1. Said antibodies are applied at the treatment of diseases related to abnormalities in bone mineral density and of bone mass.
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