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401.发明公开포제 처리된 감국 또는 진피 추출물을 함유하는 항산화용 화장료 조성물 有权含有CHRYSANUMEMIC INDICUM提取物或CITRUS UNSHIU MARKOVICH PERICARP的化妆品组合物
公开(公告)号：KR1020100056282A
公开(公告)日：2010-05-27
申请号：KR1020080115369
申请日：2008-11-19
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K8/0212 , A61K2800/522 , A61Q19/00 , A61Q19/08
Abstract: 본발명은항산화용화장료조성물에관한것으로, 보다상세하게는한방가공기술인포제()를활용하여가공된감국및 진피추출물중 1 종이상또는상기포제처리된추출물과이들의생품추출물중 1종이상을혼합한혼합추출물을유효성분으로함유하는항산화용화장료조성물에관한것이다.
Abstract translation: 目的：提供含有草药提取物的抗氧化化妆品组合物，以抑制DPPH氧化并确保抗氧化功能。 构成：用于抗氧化的化妆品组合物含有菊花或马铃薯柑橘（Citrus unshiu Markovich）提取物作为活性成分。 提取柑橘柑橘和菊花的方法包括：将蜂蜜加入到马铃薯柑橘和菊花中30分钟至1小时以吸收蜂蜜的步骤; 在100-180℃下烘烤10分钟至1小时的步骤; 和使用水或有机溶剂萃取的步骤。 有机溶剂为乙醇，甲醇，乙醚，乙酸乙酯或氯仿。
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公开(公告)号：KR1020100029369A
公开(公告)日：2010-03-17
申请号：KR1020080088127
申请日：2008-09-08
Applicant: (주)아모레퍼시픽
CPC classification number: C12P33/00
Abstract: PURPOSE: A method for preparing a green tea saponin 21-O-angeloyltheasapogenol E3 is provided to massively produce 21-O-angeloyltheasapogenol E3 through hydrolysis using microorganism. CONSTITUTION: A method for preparing 21-O-angeloyltheasapogenol E3 comprises: a step of collecting extract containing saponin from plant seeds using eater or organic solvent; and a step of hydrolyzing the extract using acid, base, enzyme, or microorganism producing the enzyme to isolate the 21-O-angeloyltheasapogenol E3 of chemical formula 1. The plant seed is green tea seed. The acid is hydrochloric acid, sulfuric acid, nitric acid, or ethanol, methanol, or butanol thereof. The base is sodium hydroxide, or potassium hydroxide, or base, ethanol, methanol, or butanol thereof. The enzyme is glucosidase, arabinosidase, rhamnosidase, xylosidase, cellulose, hesperidinase, naringinase, [glucuronidase, pectinase, galactosidase, or amyloglucosidase.
Abstract translation: 目的：提供一种绿茶皂苷21-O-异基酰基同种异构素E3的制备方法，通过微生物水解大量生产21-O-异基因己二烯E3。 构成：一种制备21-O-异基酰基己二烯E3的方法包括：使用食用或有机溶剂从植物种子中收集含有皂角苷的提取物的步骤; 使用产生该酶的酸，碱，酶或微生物水解提取物的步骤，以分离出化学式1的21-O-对映体基础油E3。植物种子是绿茶种子。 酸是盐酸，硫酸，硝酸或乙醇，甲醇或丁醇。 碱为氢氧化钠或氢氧化钾，或其碱，乙醇，甲醇或丁醇。 酶是葡糖苷酶，阿拉伯糖苷酶，鼠李糖苷酶，木糖苷酶，纤维素，橙皮苷酶，柚苷酶，[葡糖苷酸酶，果胶酶，半乳糖苷酶或淀粉葡糖苷酶。
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公开(公告)号：KR1020100000392A
公开(公告)日：2010-01-06
申请号：KR1020080059873
申请日：2008-06-24
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/498 , A61K31/352 , A61Q19/00
Abstract: PURPOSE: A method and composition for promoting skin regeneration using icariside II is provided to promote proliferation of transient amplifying cells of epidermis base and promote skin regeneration. CONSTITUTION: An icariside II of chemical formula 1 promotes proliferation of skin cells in skin cells. The skin cell is transient amplifying cells(TA cells). A composition for promoting skin regeneration contains the icariside II as an active ingredient. The content of the active ingredient is 0.001-10 weight% based on total weight. The composition regenerates epidermis by promoting proliferation of the TA cells. The composition increases the number of TA cells which express CD71 protein (Cluster of Differentiation 71 Protein) and α6 integrin. The composition increases the expression of CD200(Cluster of Differentiation 200).
Abstract translation: 目的：提供使用艾司替丁II促进皮肤再生的方法和组合物，以促进表皮碱基瞬时扩增细胞的增殖并促进皮肤再生。 构成：化学式1的阿奇瑞德II促进皮肤细胞中皮肤细胞的增殖。 皮肤细胞是瞬时扩增细胞（TA细胞）。 用于促进皮肤再生的组合物含有作为活性成分的阿魏酸二酯。 活性成分的含量为0.001-10重量％。 该组合物通过促进TA细胞的增殖而再生表皮。 该组合物增加表达CD71蛋白（分化蛋白簇71）和α6整联蛋白的TA细胞的数量。 该组合物增加CD200（分化群集200）的表达。
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公开(公告)号：KR1020090130801A
公开(公告)日：2009-12-24
申请号：KR1020080124479
申请日：2008-12-09
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A skin external composition containing ginseng seed oil or ginseng seed skin extract is provided to ensure skin improvement effect without side effects. CONSTITUTION: A skin external composition contains ginseng seed extract as an active ingredient. The ginseng seed extract is 0.001-100 weight% of ginseng seed oil or 0.001-10 weight% of ginseng seed skin extract. A method for extracting ginseng seed skin comprises: a step of pulverizing dried ginseng seed and placing the ginseng seed at room temperature in hexane organic solvent to remove oil from the ginseng seed; a step of placing the remaining ginseng seed skin in organic solvent containing water or organic solvent at room temperature; and a step of filtering extract and concentrating.
Abstract translation: 目的：提供含有人参种子油或人参种子皮肤提取物的皮肤外用组合物，以确保皮肤改善效果而没有副作用。 构成：皮肤外用组合物含有人参种子提取物作为活性成分。 人参种子提取物为人参种子油的0.001-100重量％或人参种子皮肤提取物的0.001-10重量％。 一种提取人参种子皮的方法包括：将干燥人参种子粉碎并将人参种子在室温下放置在己烷有机溶剂中以从人参种子中除去油的步骤; 在室温下将剩余的人参种子皮肤置于含水或有机溶剂的有机溶剂中的步骤; 以及过滤提取和浓缩的步骤。
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公开(公告)号：KR1020080095678A
公开(公告)日：2008-10-29
申请号：KR1020070040486
申请日：2007-04-25
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/602 , A61K8/97 , A61K9/0014 , A61K31/7048 , A61K2800/782 , A61Q19/08
Abstract: A composition for skin external application is provided to improve the skin wrinkle. A kaempferol-3-O-rutinoside suppresses a collagenase expression and accelerates a production of procollagen. A composition for skin external application for improving skin wrinkle contains the kaempferol-3-O-rutinoside expressed by a chemical formula 1. The composition is used as astringent cosmetic water, lotion, moisturizing cream, massage cream, essence, eye cream, eye essence, cleansing cream, cleansing foam, cleansing water, pack, powder, body lotion, body cream, body oil, body essence, makeup base, foundation, hair-dye, shampoo, rinse or the body cleansing agent. The kaempferol-3-O-rutinoside is separated from the green tea.
Abstract translation: 提供用于皮肤外用的组合物以改善皮肤皱纹。 山奈酚-3-O-芸香糖苷抑制胶原酶表达并促进原胶原的产生。 用于改善皮肤皱纹的皮肤外用组合物含有由化学式1表示的山奈酚-3-O-芸香苷。该组合物用作收敛化妆水，洗剂，保湿霜，按摩霜，精华液，眼霜，眼睛精华 ，清洁霜，清洁泡沫，清洁水，包装，粉末，身体乳液，身体霜，身体油，身体精华，化妆底座，粉底，染发剂，洗发水，冲洗液或身体清洁剂。 将山奈酚3-O-芸香苷与绿茶分离。
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Patent Agency Ranking
公开(公告)号：KR1020080088799A
公开(公告)日：2008-10-06
申请号：KR1020070031552
申请日：2007-03-30
Applicant: (주)아모레퍼시픽
CPC classification number: C12P17/06 , C07D311/26
Abstract: A method for preparing ortho-dihydroxyisoflavones having high antioxidative and skin-whitening effects through the biotransformation system is provided to improve the preparation yield of ortho-dihydroxyisoflavones by using microorganisms. The ortho-dihydroxyisoflavones including 7,8,4݆-trihydroxyisoflavone, 7,6,4݆-trihydroxyisoflavone, 7,3݆,4݆-trihydroxyisoflavone and 7,5,3݆,4݆-tetrahydroxyisoflavone are prepared by biotransforming daidzein and genistein with a microorganism derived from Actinomyces selected from Streptomyces evermitilis, Nocardia farcinica and Streptomyces lincolnesis through site specific hydroxylation at 3݆ site in a batch reactor to which oxygen is supplied.
Abstract translation: 提供通过生物转化体系制备具有高抗氧化和皮肤美白效果的邻二羟基异黄酮的方法，以通过使用微生物来提高邻二羟基异黄酮的制备产率。 通过生物转化黄豆苷原制备了包含7,8,4†-三羟基异黄酮，7,6,4†-三羟基异黄酮，7,3†，4†-三羟基异黄酮和7,5,3†，4Ý-四羟基异黄酮的邻二羟基异黄酮 染料木素与来自放线菌属的微生物，所述放线菌选自Streptomyces evermitilis，诺卡氏菌（Nocardia farcinica）和链霉菌链霉菌（Streptomyces lincolnesis），通过在供给氧的间歇反应器中的3'†位点进行位点特异性羟基化。
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公开(公告)号：KR1020070070303A
公开(公告)日：2007-07-04
申请号：KR1020050076557
申请日：2005-08-20
Applicant: (주)아모레퍼시픽
IPC: A61K31/352 , A61K8/97
Abstract: A composition for inhibiting sebum secretion and obesity comprising kaempferol is provided to inhibit overproduction of sebum and degrade a neutral fat accumulated in a fat cell, so that the composition is useful for prevention and treatment of diseases caused by overproduction of sebum including acnes, hair loss and seborrheic dermatitis, and obesity. The composition for inhibiting sebum secretion and obesity comprises 0.0001-10 wt.% of kaempferol obtained by degrading kaempferol glycoside with an acid, a base, an enzyme or an enzyme-producing microorganism, wherein the kaempferol glycoside is isolated from a plant, especially green tea; the acid is hydrochloric acid, sulfuric acid or nitric acid; the base is sodium hydroxide or potassium hydroxide; the enzyme is glucosidase, arabinosidase, rhamnosidase, xylosidase, cellulose, hesperidinase, naringinase, glucuronidase, pectinase, galactosidase or amylogucosidase; and the enzyme-producing microorganism is Aspergillus sp., Bacillus sp., Penicillium sp., Rhizopus sp., Rhizomucor sp., Talaromyces sp., Bifidobacterium sp., Mortierella sp., Cryptococcus sp. or Microbacterium sp.
Abstract translation: 提供了一种抑制皮脂分泌和肥胖的组合物，其包含山奈酚以抑制皮脂的过量产生并降解脂肪细胞中累积的中性脂肪，使得该组合物可用于预防和治疗由过度产生皮脂（包括痤疮），脱发 脂溢性皮炎和肥胖症。 用于抑制皮脂分泌和肥胖的组合物包含0.0001-10重量％的通过用酸，碱，酶或酶产生微生物降解山奈酚糖苷获得的山奈酚，其中山奈酚糖苷从植物中分离，特别是绿色 茶; 酸是盐酸，硫酸或硝酸; 碱为氢氧化钠或氢氧化钾; 酶是葡糖苷酶，阿拉伯糖苷酶，鼠李糖苷酶，木糖苷酶，纤维素，橙皮苷酶，柚皮苷酶，葡糖苷酸酶，果胶酶，半乳糖苷酶或淀粉糖苷酶; 酶产生微生物是曲霉属，芽孢杆菌属，青霉属，根霉属，根毛霉属，马鞭草属，双歧杆菌属，被孢霉属，隐球菌属， 或微杆菌属
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公开(公告)号：KR1020070056674A
公开(公告)日：2007-06-04
申请号：KR1020050115649
申请日：2005-11-30
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/498 , A61K8/602 , A61K2800/522 , A61Q19/02 , A61Q19/08
Abstract: A cosmetic composition comprising a hydrolysate of icariin is provided to show anti-aging effect and melanogenesis inhibition effect through expression inhibition effect, and whitening effect through improving pigmentation generated by UV, thereby being usefully used as a cosmetic composition or a pharmaceutical composition for anti-aging, whitening and wrinkle improving. The cosmetic composition comprises a hydrolysate of icariin represented by the formula(1), wherein R1 is OH or rhamnopyranose and R2 is OH or glucopyranose, provided that both R1 and R2 are not simultaneously rhamnopyranose and glucopyranose. The hydrolysate of icariin is prepared by extracting a plant using water or an organic solvent to obtain a plant extract and then hydrolyzing the plant extract using an acid, a base, an enzyme or a microorganism producing the enzyme.
Abstract translation: 提供含有淫羊藿苷水解产物的化妆品组合物，以通过表达抑制作用显示出抗衰老作用和黑素生成抑制作用，以及通过改善由UV产生的色素沉着的美白效果，从而可有效地用作化妆品组合物或抗癌药物组合物， 老化，美白和皱纹改善。 化妆品组合物包含由式（1）表示的淫羊a a水解物，其中R1是OH或吡喃糖吡喃糖，R2是OH或吡喃葡萄糖，条件是R1和R2都不是同时具有吡喃葡萄糖和吡喃葡萄糖。 通过使用水或有机溶剂提取植物来获得植物提取物，然后使用产生该酶的酸，碱，酶或微生物水解植物提取物来制备淫羊茸的水解产物。
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409.发明公开캄페롤을 유효성분으로 함유하는 피부 보습용, 피부 장벽기능 강화용, 및 피부 각질형성세포 분화 유도용 피부 외용 화장료 조성물 有权用于皮肤外用于皮肤保湿作用的组合物，用于增强皮肤屏障功能，或诱导皮肤角化细胞分化，包括山奈酚
公开(公告)号：KR1020070021853A
公开(公告)日：2007-02-23
申请号：KR1020050076551
申请日：2005-08-20
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/498 , A61K8/97 , A61K2800/80 , A61Q19/007
Abstract: 본 발명은 캄페롤을 유효성분으로 함유하는 피부 보습용, 피부 장벽 기능 강화용 및 피부 각질형성세포 분화 유도용 피부 외용제 조성물에 관한 것으로, 상기 캄페롤은 캄페롤 배당체로부터 산, 염기, 효소, 또는 상기 효소를 생산하는 미생물을 이용한 분해반응을 통해 캄페롤을 분리시켜 얻어진 것으로, 상기 캄페롤 배당체는 식물, 특히 녹차 유래인 것으로, 캄페롤 함량이 90%이상인 것을 특징으로 한다.
본 발명에 의한 상기 캄페롤은 피부 각질형성세포의 분화 촉진, 손상된 피부 장벽기능의 회복 및 피부 보습력을 증가시키는 효과를 나타낸다. 따라서, 상기 캄페롤을 함유하는 피부 외용제 조성물은 피부 보습용, 피부 장벽기능 강화용 및 피부 각질형성세포 분화 유도용으로, 표피 분화가 불완전함으로서 생기는 피부건조증, 아토피 피부염, 접촉성 피부염 또는 건선 등을 예방 또는 개선하며, 피부 보습용, 피부 장벽기능 강화용 및 피부 각질형성세포 분화 유도용 화장료 조성물 또는 약학 조성물로 유용하게 사용할 수 있다.
캄페롤, 피부, 보습, 외용제, 배당체, 산, 염기, 효소, 미생물, 식물, 녹차, 장벽기능, 각질형성세포, 아토피, 화장료, 약학, 조성물.-
公开(公告)号：KR1020060083778A
公开(公告)日：2006-07-21
申请号：KR1020050004715
申请日：2005-01-18
Applicant: (주)아모레퍼시픽
IPC: C12P17/06
CPC classification number: C12P17/06
Abstract: 본 발명은 캄페롤 배당체로부터 산, 염기, 효소 또는 상기 효소를 생산하는 미생물을 이용하여 캄페롤(kaempferol)을 분리하는 것을 특징으로 하는 캄페롤 제조방법에 관한 것으로, 보다 상세하게는 식물로부터 물 또는 유기용매를 이용하여 캄페롤 배당체를 함유하는 식물 추출물을 수득하는 제 1 단계; 및 상기 식물 추출물을 산, 염기, 효소 또는 상기 효소를 생산하는 미생물을 이용하여 가수분해하여 캄페롤을 분리하는 제 2 단계를 포함하는 것을 특징으로 하는 캄페롤을 제조하는 방법에 관한 것으로, 상기, 캄페롤 배당체는 카멜리아시드 A(camelliaside A) 또는 카멜리아시드 B(camelliaside B)를 포함하는 것을 특징으로 하며, 상기 식물 추출물은 녹차 씨 또는 녹차 잎으로부터 유래된 것임을 특징으로 한다. 본 발명의 상기 방법을 이용하면, 식물 특히, 녹차 씨와 녹차 잎으로부터 주요한 생리활성물질인 캄페롤을 대량으로 생산할 수 있다.
캄페롤, 배당체, 식물, 추출물, 산, 염기, 효소, 미생물, 카멜리아시드, 녹차 씨, 녹차 잎
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