公开(公告)号：WO2015148781A1

公开(公告)日：2015-10-01

申请号：PCT/US2015/022696

申请日：2015-03-26

Applicant: UNIVERSITY OF HOUSTON SYSTEM ,  ROBLES, Francisco C. ,  CALDERON, Hector A. ,  OKONKWO, Anderson

Inventor： ROBLES, Francisco C. ,  CALDERON, Hector A. ,  OKONKWO, Anderson

IPC: C01B31/02 ,  C08K3/04 ,  C04B35/52 ,  B82Y30/00 ,  B82Y40/00

CPC classification number: B29C43/006 ,  B29L2031/3055 ,  B29L2031/3076 ,  B29L2031/34 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/15 ,  C01B32/184 ,  C01B32/20 ,  C03C14/002 ,  C03C2214/02 ,  C03C2214/16 ,  C04B35/00 ,  C04B35/6261 ,  C04B35/645 ,  C04B2235/422 ,  C04B2235/425 ,  C04B2235/427 ,  C04B2235/5409 ,  C08K3/04 ,  C08K2201/006 ,  C22C1/1084 ,  C22C26/00 ,  C22C2026/001

Abstract: A methodology is disclosed to produce nanostructured carbon particles that act as effective reinforcements. The process is conducted in the solid state at close to ambient conditions. The carbon nanostructures produced under this discovery are nanostructured and are synthesized by mechanical means at standard conditions. The benefit of this processing methodology is that those carbon nanostructures can be used as effective reinforcements for composites of various matrices. As example, are to demonstrate its effectiveness the following matrices were including in testing: ceramic, metallic, and polymeric (organic and inorganic), as well as bio-polymers. The reinforcements have been introduced in those matrices at room and elevated temperatures. The raw material is carbon soot that is a byproduct and hence abundant and cheaper than pristine carbon alternatives (e.g. nanotubes, graphene).

Abstract translation: 公开了一种用于生产作为有效增强材料的纳米结构碳颗粒的方法。 该过程在接近环境条件下以固态进行。 在该发现下产生的碳纳米结构是纳米结构的，并且通过机械手段在标准条件下合成。 这种处理方法的好处是，这些碳纳米结构可以用作各种基质的复合材料的有效增强材料。 例如，要证明其有效性，以下矩阵包括在测试中：陶瓷，金属和聚合物（有机和无机）以及生物聚合物。 在室内和升高的温度下，这些基体已经引入了增强物。 原料是碳烟，它是副产物，因此比原始碳替代物（例如纳米管，石墨烯）更丰富和便宜。

公开(公告)号：WO2015148527A1

公开(公告)日：2015-10-01

申请号：PCT/US2015/022277

申请日：2015-03-24

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： BENSAOULA, Abdelhak ,  STARIKOV, David ,  PILLAI, Rajeev

IPC: H01L31/107 ,  H01L31/0256 ,  H01L31/02

CPC classification number: H01L31/1075 ,  H01L21/02389 ,  H01L21/02458 ,  H01L21/02513 ,  H01L21/0254 ,  H01L21/02631 ,  H01L27/1446 ,  H01L31/03044 ,  H01L31/03048 ,  H01L31/035236 ,  H01L31/035281 ,  H01L31/1848 ,  H01L31/1852 ,  H01L31/1856 ,  Y02E10/544

Abstract: The structure and method of fabricating a radiation and temperature hard avalanche photodiode with integrated radiation and temperature hard readout circuit, comprising a substrate, an avalanche region, an absorption region, and a plurality of Ohmic contacts are presented. The present disclosure provides for tuning of spectral sensitivity and high device efficiency, resulting in photon counting capability with decreased crosstalk and reduced dark current.

Abstract translation: 提供了具有集成的辐射和温度硬读出电路的辐射和温度硬雪崩光电二极管的结构和方法，其包括衬底，雪崩区域，吸收区域和多个欧姆接触。 本公开提供了光谱灵敏度的调谐和高的器件效率，导致光子计数能力，减少的串扰和减少的暗电流。

公开(公告)号：WO2015148493A1

公开(公告)日：2015-10-01

申请号：PCT/US2015/022229

申请日：2015-03-24

Applicant: UNIVERSITY OF HOUSTON SYSTEM ,  KOZINSKY, Boris

Inventor： KOZINSKY, Boris ,  JOSHI, Giri ,  YANG, Jian ,  ENGBER, Michael ,  PANTHA, Tej ,  CLEARY, Martin ,  REN, Zhifeng ,  HE, Ran

IPC: H01L35/12 ,  H01L35/14

CPC classification number: H01L35/18 ,  B22F2998/10 ,  C22C1/04 ,  C22C12/00 ,  C22C33/0278 ,  C22C38/00 ,  H01L35/20 ,  H01L35/34 ,  B22F9/08 ,  B22F2009/043 ,  B22F3/14 ,  B22F2003/248

Abstract: A thermoelectric half-Heusler material comprising niobium (Nb), iron (Fe) and antimony (Sb) wherein the material comprises grains having a mean grain size less than one micron. A method of making a nanocomposite half-Heusler thermoelectric material includes melting constituent elements of the thermoelectric material to form an alloy of the thermoelectric material, comminuting (e.g., ball milling) the alloy of the thermoelectric material into nanometer scale mean size particles, and consolidating the nanometer size particles to form the half-Heusler thermoelectric material comprising at least niobium (Nb), iron (Fe) and antimony (Sb) and having grains with a mean grain size less than one micron.

Abstract translation: 包含铌（Nb），铁（Fe）和锑（Sb）的热电半Heusler材料，其中该材料包含平均晶粒尺寸小于1微米的晶粒。 制造纳米复合半合金热电材料的方法包括熔化热电材料的组成元素以形成热电材料的合金，将热电材料的合金粉碎（例如，球磨）成纳米尺度的平均粒度的颗粒，并且将 纳米尺寸的颗粒形成至少包含铌（Nb），铁（Fe）和锑（Sb）并具有平均晶粒尺寸小于1微米的晶粒的半赫斯勒热电材料。

公开(公告)号：WO2015127037A1

公开(公告)日：2015-08-27

申请号：PCT/US2015/016560

申请日：2015-02-19

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： BOSE, Rathindra, N.

IPC: A61K31/282 ,  C07F15/00 ,  C07F9/6571 ,  C07F9/655 ,  A61P25/00

CPC classification number: A61K31/555

Abstract: In some embodiments, the present disclosure pertains to a composition for modulating the expression of at least one gene associated with neuronal cell survival or stability. In some embodiments, the present disclosure provides for compositions for the treatment of neurodegenerative diseases comprising one or more phosphate complexes of platinum of the formulas I, II, III and IV as set forth in FIG. 1. In some embodiments, the present disclosure relates to a method of treating a neurodegenerative disorder comprising administering therapeutically effective amounts of at least one of the aforementioned compositions described supra to a subject in need thereof, such that the compounds are effective in modulating the expression of a gene selected from the group consisting of NMDA-receptor, ATF, PPT2, HPD, EGR2, SLC7A11, FosB, SQSTM1, TMEM106B, RAB27A, STOX1, and SLC39A3.

Abstract translation: 在一些实施方案中，本公开涉及用于调节与神经元细胞存活或稳定性相关的至少一种基因的表达的组合物。 在一些实施方案中，本公开提供用于治疗神经变性疾病的组合物，其包含如图1所示的式I，II，III和IV的铂的一种或多种磷酸盐复合物。 在一些实施方案中，本公开涉及治疗神经变性疾病的方法，其包括向有需要的受试者施用治疗有效量的上述组合物至上述组合物，使得所述化合物有效调节表达 选自NMDA受体，ATF，PPT2，HPD，EGR2，SLC7A11，FosB，SQSTM1，TMEM106B，RAB27A，STOX1和SLC39A3的基因。

公开(公告)号：WO2015126817A1

公开(公告)日：2015-08-27

申请号：PCT/US2015/016130

申请日：2015-02-17

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： REN, Zhifeng ,  ZHAO, Huaizhou ,  TANG, Zhongjia ,  SUI, Jiehe ,  LAN, Yucheng ,  JIE, Qing

IPC: H01L35/14

CPC classification number: C22C23/00 ,  B22F1/0003 ,  B22F3/15 ,  B22F9/04 ,  B22F2009/043 ,  B22F2301/058 ,  B22F2998/10 ,  C22C1/0408 ,  H01L35/14 ,  H01L35/18 ,  H01L35/34

Abstract: Systems and methods of manufacturing a thermoelectric, high performance material by using ball-milling and hot pressing materials according to various formulas, where some formulas substitute a different element for part of one of the elements in the formula, in order to obtain a figure of merit (ZT) suitable for thermoelectric applications.

Abstract translation: 通过使用根据各种配方的球磨和热压材料制造热电高性能材料的系统和方法，其中一些配方将不同元素替代为式中一个元素的一部分，以获得 优点（ZT）适用于热电应用。

公开(公告)号：WO2015120272A1

公开(公告)日：2015-08-13

申请号：PCT/US2015/014818

申请日：2015-02-06

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： RIMER, Jeffrey, D. ,  ASPLIN, John

IPC: A61K31/194 ,  A61K31/19 ,  A61P13/12

CPC classification number: A61K31/194

Abstract: In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium oxalate crystal growth. In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium phosphate crystal growth. In some embodiments, such a composition comprises at least one citrate derivative of an organic acid and at least one pharmaceutically acceptable carrier. In another embodiment, the present disclosure relates to a method of controlling calcium oxalate crystal growth in a subject in need thereof. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.

Abstract translation: 在本公开的一个实施方案中，提供了用于抑制草酸钙晶体生长的组合物。 在本公开的一个实施方案中，提供了一种抑制磷酸钙晶体生长的组合物。 在一些实施方案中，这样的组合物包含至少一种有机酸的柠檬酸盐衍生物和至少一种药学上可接受的载体。 在另一个实施方案中，本公开内容涉及在有需要的受试者中控制草酸钙晶体生长的方法。 这种方法包括向受试者施用有效量的上述组合物。 在另一个实施方案中，本公开涉及治疗肾结石病症的方法。 这种方法包括向有需要的受试者施用治疗有效量的上述组合物。 在另一个实施方案中，本公开涉及治疗草酸钙石病的方法。 在一个实施方案中，该方法包括向有需要的受试者施用治疗有效量的上述组合物。

公开(公告)号：WO2015100245A1

公开(公告)日：2015-07-02

申请号：PCT/US2014/071912

申请日：2014-12-22

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： RYOU, Jae-Hyun

IPC: H01L21/20

CPC classification number: H01L27/12 ,  H01L21/02002 ,  H01L21/02639 ,  H01L21/2007 ,  H01L27/1266 ,  H01L29/04

Abstract: Systems and methods herein relate to the fabrication of a single-crystal flexible semiconductor template that may be attached to a semiconductor device. The template fabricated comprises a plurality of single crystals grown by lateral epitaxial growth on a seed layer and bonded to a flexible substrate. The layer grown has portions removed to create windows that add to the flexibility of the template.

Abstract translation: 本文的系统和方法涉及可以附接到半导体器件的单晶柔性半导体模板的制造。 制造的模板包括通过种子层上的横向外延生长而生长并结合到柔性基底上的多个单晶。 生成的图层部分被删除以创建窗口，增加了模板的灵活性。

公开(公告)号：WO2015070162A3

公开(公告)日：2015-05-14

申请号：PCT/US2014/064844

申请日：2014-11-10

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： POLLONINI, Luca ,  PARAZYNSKI, Scott E. ,  FORSETH, Kiefer

IPC: A61B5/00 ,  A61B5/1455

Abstract: Embodiments described herein generally relate to devices, methods and systems for determining blood oxygenation. By applying near infrared radiation of an appropriate wavelength to the tissue and determining the absorbance at a plurality of points where the distance between the source of the near infrared radiation and the detector are known, the oxygenation state of the hemoglobin can be determined based on position in a three dimensional space.

公开(公告)号：WO2013149038A1

公开(公告)日：2013-10-03

申请号：PCT/US2013/034410

申请日：2013-03-28

Applicant: UNIVERSITY OF HOUSTON SYSTEM

Inventor： ZOURIDAKIS, George

IPC: G06K9/78 ,  A61B5/00

CPC classification number: G06T7/0012 ,  A61B5/0077 ,  A61B5/444 ,  G06K2209/05 ,  G06K2209/053 ,  G06T2207/10024 ,  G06T2207/20081 ,  G06T2207/30088

Abstract: Provided herein are portable imaging systems, for example, a digital processor- implemented system for the identification and/or classification of an object of interest on a body, such as a human or plant body. The systems comprise a hand-held imaging device, such as a smart device, and a library of algorithms or modules that can be implemented thereon to process the imaged object, extract representative features therefrom and classify the object based on the representative features. Also provided are methods for the identifying or classifying an object of interest on a body that utilize the algorithms and an automated portable system configured to implement the same.

Abstract translation: 本文提供了便携式成像系统，例如用于识别和/或分类身体（例如人或植物体）上的感兴趣对象的数字处理器实现的系统。 这些系统包括诸如智能设备的手持成像设备和可以在其上实现的处理成像对象的算法或模块库，从中提取代表性特征并基于代表性特征对对象进行分类。 还提供了用于识别或分类利用算法的身体上的感兴趣对象的方法和被配置为实现该算法的自动便携式系统。

公开(公告)号：WO2012051182A2

公开(公告)日：2012-04-19

申请号：PCT/US2011/055771

申请日：2011-10-11

Applicant: UNIVERSITY OF HOUSTON SYSTEM ,  YU, Qingkai ,  PEI, Shin-Shem

Inventor： YU, Qingkai ,  PEI, Shin-Shem

IPC: C01B31/02 ,  C23C16/26 ,  C30B29/02 ,  B82B3/00

CPC classification number: B82Y40/00 ,  B82Y30/00 ,  C01B32/186 ,  C01B2204/32

Abstract: The present disclosure demonstrates the synthesis of ordered arrays of GSC's by re- growth from pre-patterned seed crystals, offering an approach for scalable fabrication of single crystal graphene devices while avoiding domain boundaries. Each graphene island is a single crystal and every graphene island is of similar size. The size of graphene island arrays can be as small as less than 1 mm 2 or as large as several m 2 . The distance between each GSC island is also adjustable from several micrometers to millimeters. All of the graphene islands are addressable for devices and electrical circuit fabrication.

Abstract translation: 本公开内容显示了通过从预先图案化的晶种再生成合成GSC的有序阵列，为避免畴边界提供了单晶石墨烯器件的可扩展制造方法。 每个石墨烯岛是单晶，每个石墨烯岛的大小相似。 石墨烯岛阵列的尺寸可以小至小于1mm2或大至几平方米。 每个GSC岛之间的距离也可以从几微米到毫米。 所有的石墨烯岛可寻址器件和电路制造。