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公开(公告)号:CA2347618A1
公开(公告)日:2001-03-15
申请号:CA2347618
申请日:2000-08-29
Applicant: BAXTER INT
Inventor: MULLER MATTHEW R , WESTBERG TOM , JOIE MICHEL L F , VISHNOI ROHIT , SMITH KELLY B , VANDLIK MARK R
IPC: G01N33/48 , A61M1/02 , A61M1/34 , A61M1/36 , B01D17/02 , B01D21/24 , B04B5/00 , G01N21/27 , G01N21/35 , G01N33/483 , G01N33/49 , B01D21/26 , A61M1/38
Abstract: Blood processing systems and methods employ two sensors (334, 336), one (334 ) to detect a condition of plasma exiting a separation device (18) and another sensor (336) to detect a condition of a cellular component exiting the separation device (18). The first sensor (334) detects, e.g., contamination of the plasma due to the presence of unwanted cellular components. The second sensor (336) detects, e.g., dilution of the cellular component due to presen ce of plasma. Blood processing parameters are carried out based, at least in part, by conditions detected by one or both of the sensors (334, 336).
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公开(公告)号:CA2462718C
公开(公告)日:2010-08-17
申请号:CA2462718
申请日:2002-10-02
Applicant: BAXTER INT
Inventor: SMITH KELLY B , VANDLIK MARK R , KAST MICHAEL J
IPC: A61M1/02 , A61M37/00 , A61K35/14 , A61K35/18 , A61M1/10 , A61M1/30 , A61M1/34 , A61M1/36 , A61P7/00 , B01D33/15 , C02F1/00
Abstract: Blood processing systems and methods (10) convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alternate the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.
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公开(公告)号:CA2397959C
公开(公告)日:2007-07-03
申请号:CA2397959
申请日:2001-11-13
Applicant: BAXTER INT
Inventor: ODAK SANJAY V , WESTBERG TOM , VANDLIK MARK R
Abstract: A pneumatic pump manifold disposable system, configured as a cassette, is us ed for the purpose of red cell and plasma apheresis. The cassette (16) integrates a separation device (44) such as a spinning membrane separator, a controller and a fluid flow circuit (42) for the purpose of separating plasma and red cells from the whole blood. The cassette system, with the separation device (44) directly attached without tubing, simplfies the loadi ng of the disposable set into the hardware such as a case (20), and reduces the manufacturing complexity of the set. The system allows for plasma, buffy coat and red cells to be stored in long term storage containers (54, 56 and 58) after a procedure.
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公开(公告)号:BR0213200A
公开(公告)日:2006-05-23
申请号:BR0213200
申请日:2002-10-02
Applicant: BAXTER INT
Inventor: SMITH KELLY B , VANDLIK MARK R , KAST MICHAEL J
IPC: A61M1/02 , A61K35/14 , A61K35/18 , A61M1/10 , A61M1/30 , A61M1/34 , A61M1/36 , A61P7/00 , A61M37/00 , C02F1/00 , B01D33/15
Abstract: Blood processing systems and methods convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alternate the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.
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公开(公告)号:CA2397959A1
公开(公告)日:2002-07-25
申请号:CA2397959
申请日:2001-11-13
Applicant: BAXTER INT
Inventor: VANDLIK MARK R , ODAK SANJAY V , WESTBERG TOM
Abstract: A pneumatic pump manifold disposable system, configured as a cassette, is us ed for the purpose of red cell and plasma apheresis. The cassette (16) integrat es a separation device (44) such as a spinning membrane separator, a controller and a fluid flow circuit (42) for the purpose of separating plasma and red cells from the whole blood. The cassette system, with the separation device (44) directly attached without tubing, simplfies the loading of the disposab le set into the hardware such as a case (20), and reduces the manufacturing complexity of the set. The system allows for plasma, buffy coat and red cell s to be stored in long term storage containers (54, 56 and 58) after a procedu re.
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公开(公告)号:NO20012172L
公开(公告)日:2001-07-02
申请号:NO20012172
申请日:2001-05-02
Applicant: BAXTER INT
Inventor: WESTBERG TOM , VISHNOI ROHIT , VANDLIK MARK R
Abstract: Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.
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公开(公告)号:NO20012172A
公开(公告)日:2001-07-02
申请号:NO20012172
申请日:2001-05-02
Applicant: BAXTER INT
Inventor: WESTBERG TOM , VISHNOI ROHIT , VANDLIK MARK R
CPC classification number: A61M1/3696 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3633 , A61M2205/128 , A61M2205/331 , A61M2205/3334 , A61M2205/3393 , F04B13/02 , F04B43/026 , F04B49/065 , F04B2205/09
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公开(公告)号:NO20012171D0
公开(公告)日:2001-05-02
申请号:NO20012171
申请日:2001-05-02
Applicant: BAXTER INT
Inventor: VISHNOI ROHIT , WESTBERG TOM , MULLER MATTHEW R , SMITH KELLY B , JOIE MICHEL L F , VANDLIK MARK R
IPC: G01N33/48 , A61M1/02 , A61M1/34 , A61M1/36 , B01D17/02 , B01D21/24 , B04B5/00 , G01N21/27 , G01N21/35 , G01N33/483 , G01N33/49 , B01D
Abstract: A blood separation system (10) is described. The system comprises a device (14, 18) which, in use, operates to separate whole blood into red blood cells and plasma, a whole blood inlet line (290) for conveying a flow of whole blood into the device, a plasma collection line (292) for conveying a flow of plasma from the device, and a red blood cell collection line (294) for conveying a flow of red blood cells from the device. A first sensing assembly (334) including a first sensor in the plasma collection line is provided which in use operates to detect a characteristic of plasma in the flow of plasma and to generate a first output. A second sensing assembly (336) including a second sensor in the red blood cell collection line is provided which in use operates to detect a characteristic of red blood cells in the flow of red blood cells and to generate a second output. A controller (16) operates to control flows in the plasma collection line and the red blood cell collection line based upon the first and second outputs.
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公开(公告)号:AU7086100A
公开(公告)日:2001-04-10
申请号:AU7086100
申请日:2000-08-29
Applicant: BAXTER INT
Inventor: MULLER MATTHEW R , JOIE MICHEL L T , VANDLIK MARK R
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公开(公告)号:CA2347130A1
公开(公告)日:2001-03-15
申请号:CA2347130
申请日:2000-08-29
Applicant: BAXTER INT
Inventor: VANDLIK MARK R , WESTBERG TOM , VISHNOI ROHIT
IPC: A61M1/02 , A61M1/10 , A61M1/30 , A61M1/36 , A61M37/00 , F04B17/00 , F04B35/00 , F04B49/00 , B01D37/00 , B01D61/00 , B01D63/00 , C02F1/00 , F04B9/08 , C02F1/44
Abstract: A multiple function pump station (PPN) performs different on-line processing tasks. The pump station can be operated in one mode to draw blood from a don or and can in another mode be operated to return blood to the donor. The pump station used to draw blood from a donor can also be used to perform subseque nt blood processing tasks, such as mixing processing or additive fluids with th e blood, or transferring a harvested blood component to a storage container, o r finishing the processing of a harvested blood component, e.g., by passage through a filter (200) to remove leukocytes.
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