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    MULTIPLE ELECTRODE SUPPORT STRUCTURES HAVING OPTIMAL BIO-MECHANICAL CHARACTERISTICS
    41.
    发明申请
    MULTIPLE ELECTRODE SUPPORT STRUCTURES HAVING OPTIMAL BIO-MECHANICAL CHARACTERISTICS 审中-公开
    具有最佳生物机械特性的多电极支撑结构

    公开(公告)号：WO1997017905A1

    公开(公告)日：1997-05-22

    申请号：PCT/US1996018332

    申请日：1996-11-12

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  KORDIS, Thomas, F. ,  PANESCU, Dorin ,  WHAYNE, James, G.

    IPC: A61B17/39

    CPC classification number: A61B5/6852 ,  A61B5/0422 ,  A61B5/6858 ,  A61B18/14 ,  A61B18/1492 ,  A61B18/18 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2018/1465 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056

    Abstract: An electrode support structure comprises a distal hub (48) and a proximal base (12) aligned along a major axis with the distal hub (48). An array of generally flexible spline elements (180) extends between the hub (48) and the base (12). The spline elements (180) each have an elongated axis that, at the base (12), extends generally parallel to the major axis and, at the hub (48), extends at an angle measured relative to the major axis of between 45 degrees and 110 degrees. The spline elements (180) collectively define a distal surface (66) lying within an envelope that approximates the curvature of endocardial tissue and within which envelope the distal hub (48) lies. According to this aspect of the invention, the distal surface (66), when contacting endocardial tissue, increases in surface area in response to force applied generally along the major axis to mediate tissue pressure.

    Abstract translation: 电极支撑结构包括远端轮毂（48）和沿着长轴与远侧轮毂（48）对准的近侧基座（12）。 大致柔性的花键元件（180）的阵列在轮毂（48）和基座（12）之间延伸。 所述花键元件（180）各自具有细长轴线，所述细长轴线在所述基部（12）处大体上平行于所述长轴线延伸，并且在所述轮毂（48）处以相对于所述长轴测量的角度之间延伸45度 和110度。 花键元件（180）共同地限定位于包络内的远侧表面（66），其近似心内膜组织的曲率，并且远端轮毂（48）位于该远端表面内。 根据本发明的这个方面，当远端表面（66）接触心内膜组织时，响应于通常沿着长轴施加的力而介导组织压力的表面积增加。

    SYSTEMS AND METHODS FOR MAKING TIME-SEQUENTIAL MEASUREMENTS OF BIOLOGICAL EVENTS
    44.
    发明申请
    SYSTEMS AND METHODS FOR MAKING TIME-SEQUENTIAL MEASUREMENTS OF BIOLOGICAL EVENTS 审中-公开
    制作生物事件时间序列测量的系统和方法

    公开(公告)号：WO1996025095A1

    公开(公告)日：1996-08-22

    申请号：PCT/US1996002090

    申请日：1996-02-14

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin

    IPC: A61B05/0402

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/6858 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056 ,  A61N1/3702 ,  A61N1/403

    Abstract: Analog or digital systems (10) and methods generate a composite signal derived from a biological event in a time sequential fashion. A first set of signals derived from a biological event using a first group of sensors (20) during a first time interval is input. A second set of signals derived from the biological event during a second time interval sequentially after the first time interval using a second group of sensors (36) is input. The second group of sensors has at least one common sensor that is part of the first group and other sensors that are not part of the first group. The first and second sets of signals are time aligned using signals sensed by the at least one common sensor, thereby generating the composite signal. The time alignment is done by shifting the first and second sets of signals either with or without computing a time difference between them.

    Abstract translation: 模拟或数字系统（10）和方法以时间顺序的方式产生从生物事件导出的复合信号。 输入在第一时间间隔期间使用第一组传感器（20）从生物事件导出的第一组信号。 输入使用第二组传感器（36）在第一时间间隔之后的第二时间间隔期间从生物事件导出的第二组信号。 第二组传感器具有至少一个共同的传感器，其是第一组的一部分和不是第一组的一部分的其它传感器。 使用由至少一个公共传感器感测的信号来对第一和第二组信号进行时间对准，从而产生复合信号。 时间对准是通过移动第一和第二组信号来完成的，无论是否计算它们之间的时间差。

    SYSTEM FOR EXAMINING CARDIAC TISSUE ELECTRICAL CHARACTERISTICS
    48.
    发明申请
    SYSTEM FOR EXAMINING CARDIAC TISSUE ELECTRICAL CHARACTERISTICS 审中-公开
    检查心脏组织电学特征的系统

    公开(公告)号：WO1995020344A1

    公开(公告)日：1995-08-03

    申请号：PCT/US1995001085

    申请日：1995-01-27

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  SWANSON, David, K. ,  MIROTZNIK, Mark, S. ,  SCHWARTZMAN, David, S. ,  FOSTER, Kenneth, R.

    IPC: A61B05/04

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/05 ,  A61B5/053 ,  A61B5/0538 ,  A61B5/6858 ,  A61B18/00 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056

    Abstract: Systems and methods examine heart tissue morphology using three or more spaced apart electrodes (38), at least two of which are located within the heart (12) in contact with endocardial tissue. The systems and methods transmit electrical current through a region of heart tissue lying between selected pairs of the electrodes (38), at least one of the electrodes (38) in each pair being located within the heart (12). The systems and methods derive the electrical characteristic of tissue lying between the electrode (38) pairs based, at least in part, upon sensing tissue impedances. The systems and methods make possible the use of multiple endocardial electrodes (38) for making multiple measurements of the electrical characteristics of heart tissue. Multiplexing can be used to facilitate date processing. The systems and methods almost make possible the identification of regions of low relative electrical characteristics, indicative of infarcted tissue, without invasive surgical techniques.

    Abstract translation: 系统和方法使用三个或更多个间隔开的电极（38）检查心脏组织形态，其中至少两个电极位于与心内膜组织接触的心脏（12）内。 系统和方法通过位于选定的电极对（38）之间的心脏组织的区域传输电流，每对电极（38）中的至少一个位于心脏（12）内。 系统和方法至少部分地基于感测组织阻抗而导出位于电极（38）对之间的组织的电特性。 系统和方法使得可以使用多个心内膜电极（38）来进行心脏组织的电特性的多个测量。 可以使用多路复用来进行日期处理。 系统和方法几乎可以识别低相对电特征的区域，指示梗死组织，无侵入性手术技术。

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