公开(公告)号：ES2079666T3

公开(公告)日：1996-01-16

申请号：ES91910611

申请日：1991-06-08

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  KANSCHIK-CONRADSEN ANDREAS ,  PRESSLER WILFRIED

IPC: B01J31/02 ,  C07B61/00 ,  C07C201/12 ,  C07C201/14 ,  C07C205/12

Abstract: PCT No. PCT/EP92/01079 Sec. 371 Date Dec. 22, 1992 Sec. 102(e) Date Dec. 22, 1992 PCT Filed Jun. 8, 1991 PCT Pub. No. WO91/00270 PCT Pub. Date Jan. 9, 1992A process for the preparation of chlorofluoronitrobenzenes and difluoronitrobenzenes, which comprises heating dichloronitrobenzene to not more than 200 DEG C. in excess with an alkali metal fluoride having a total water content of about 0.2 to about 2.5% by weight in the presence of a quaternary ammonium and/or phosphonium salt, crown ether and/or polyethylene glycol dimethyl ether as catalyst in the absence of a solvent.

公开(公告)号：CA2142248A1

公开(公告)日：1995-08-12

申请号：CA2142248

申请日：1995-02-10

Applicant: HOECHST AG

Inventor： SCHACH THOMAS ,  PAPENFUHS THEODOR

IPC: C07D213/73 ,  B01J23/44 ,  C07B61/00 ,  C07C209/36 ,  C07C209/74 ,  C07C211/52 ,  C07C211/59 ,  C07C213/00 ,  C07C221/00 ,  C07C223/06 ,  C07C225/22 ,  C07C253/30 ,  C07C255/58 ,  C07C215/74 ,  C07C217/78

Abstract: The invention relates to a process for preparing fluoroanilines of the formula (I) FnArNH2 (I) in which n is 1, 2, 3 or 4, Ar is phenyl, naphthyl or pyridyl, and the remaining substituents on the Ar radical are identical or different and are, independently of each other, hydrogen, halogen, (C1-C4)-alkyl, phenyl, NR2, OR, CN, CHO, or COR, where R is hydrogen or (C1-C6)-alkyl, wherein fluoronitrobenzenes of the formula (II) XmFnArNO2 (II) in which n, Ar and the remaining substituents on the Ar radical have the abovementioned meaning, X is chlorine or bromine and m is 1, 2, 3 or 4, are reacted with hydrogen in the presence of a palladium catalyst, of an amine which is not soluble in water and which also does not form watersoluble hydrohalides, and, where appropriate, of an inert solvent.

公开(公告)号：CA2132292A1

公开(公告)日：1995-03-19

申请号：CA2132292

申请日：1994-09-16

Applicant: HOECHST AG

Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR

IPC: B01J31/26 ,  C07B61/00 ,  C07C67/10 ,  C07C69/84 ,  C07C69/88 ,  C07C69/92 ,  C07C67/11

Abstract: The present invention relates to a process for preparing alkyl 3-hydroxy-2,4,5-trifluorobenzoate and/or alkyl 3alkoxy-2,4,5-trifluorobenzoate by reacting 3-hydroxy-2,4,5-trifluorobenzoic acid with a dialkyl carbonate at 80 to 200.degree.C.

公开(公告)号：CA2128469A1

公开(公告)日：1995-01-22

申请号：CA2128469

申请日：1994-07-20

Applicant: HOECHST AG

Inventor： SCHACH THOMAS ,  PAPENFUHS THEODOR

IPC: B01J31/02 ,  C07B61/00 ,  C07C201/12 ,  C07C205/12 ,  C07C205/11

Abstract: Process for preparing multiply fluorinated nitrobenzenes Multiply, preferably doubly or triply, fluorinated nitrobenzenes are prepared in an advantageous way from the corresponding chloronitrobenzenes and an alkali metal fluoride in a chlorine-fluorine exchange reaction by catalyzing the reaction with a quaternary ammonium compound comprising at least one alkoxypolyoxyalkyl radical.

公开(公告)号：CA2128465A1

公开(公告)日：1995-01-22

申请号：CA2128465

申请日：1994-07-20

Applicant: HOECHST AG

Inventor： SCHACH THOMAS ,  PAPENFUHS THEODOR ,  PFIRMANN RALF

IPC: B01J31/02 ,  C07B61/00 ,  C07C253/30 ,  C07C255/50

Abstract: Process for preparing fluorobenzonitriles Fluorobenzonitriles and chlorofluorobenzonitriles are prepared in an advantageous manner from the corresponding chlorobenzonitriles and an alkali metal fluoride in a chlorine-fluorine exchange reaction, by catalyzing the reaction with a quaternary ammonium compound comprising at least one alkoxypolyoxyalkyl radical.

公开(公告)号：CA2114504A1

公开(公告)日：1994-07-30

申请号：CA2114504

申请日：1994-01-28

Applicant: HOECHST AG

Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR ,  WEICHSELBAUMER GEORG

IPC: C07B61/00 ,  C07C45/63 ,  C07C47/55 ,  C07C51/363 ,  C07C63/70 ,  C07C67/307 ,  C07C69/78 ,  C07C231/12 ,  C07C233/65 ,  C07C253/30 ,  C07C255/50 ,  C07C69/76

Abstract: of the disclosure The present invention relates to a process for the preparation of compounds of the formula (I), in which R1 is -CN, -COOH, -COOR', R' being an organic radical having 1 to 6 carbon atoms, -CONH2, -COCl or -CHO and R2 is H or Cl, which comprises reacting a compound of the formula (II), in which R1 is as defined above and R3 is H or Cl, with a chlorinating agent in the presence of a chlorination catalyst at -10 to 200.degree.C.

公开(公告)号：IN173259B

公开(公告)日：1994-03-19

申请号：IN227CA1992

申请日：1992-04-06

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  PFIRMANN RALF

IPC: C07C63/08

公开(公告)号：MX171862B

公开(公告)日：1993-11-22

申请号：MX1055188

申请日：1988-02-25

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  DAUB WOLFGANG

IPC: C07C231/00 ,  C07C233/02 ,  C07C233/16 ,  C07C235/74 ,  C07C255/49 ,  C07C255/52 ,  C07C303/40 ,  C07C309/51 ,  C07C311/15 ,  C07D213/75 ,  C07D215/38 ,  C07D217/22

Abstract: Acetoacetylarylamides or -heteroarylamides of deactivated aromatic compounds or heteroaromatic compounds are prepared by reacting 1 mole of an amine of the formula in which X and Y in each case represent CH or one of the two ring members X and Y represents a nitrogen atom, R represents a hydrogen or halogen atom, an alkyl, beta -hydroxyethyl, benzyl or optionally substituted phenyl group, and A represents a fused benzene ring, where the isocyclic or heterocyclic six-membered ring is substituted by 1 or 2 further substituents and the benzene ring A can be substituted by 1 to 3 substituents, with 1 to 1.2 moles of diketene at temperatures from 20 to 100 DEG C in glacial acetic acid in the presence of 1 to 20 mol per cent of a basic catalyst such as tertiary amine, fluoride, acetate, trifluoromethanesulphonate, trifluoroacetate, benzoate, o-, m-, p-alkyl-C1-C4-benzoate, o-, m-, p-alkoxy-C1-C4-benzoate or o-, m-, p-di(alkyl-C1-C4-amino)benzoate, relative to the amine, where the substituent is converted into the group.

公开(公告)号：CA2089938A1

公开(公告)日：1993-08-21

申请号：CA2089938

申请日：1993-02-19

Applicant: HOECHST AG

Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR

IPC: B01J31/24 ,  C07B61/00 ,  C07D213/61 ,  C07D213/84

Abstract: Process for the preparation of substituted 2,3-difluoro-pyridines The invention relates to a novel process for the preparation of substituted 2,3-difluoropyridines by reaction of substituted 2,3-halopyridines with fluoride salts in the presence of phase transfer catalysts, preferably in polar aprotic solvents, without removing the resulting substituted 2,3-difluoropyridines continuously from the reaction mixture. The substituted 2,3-difluoropyridines which can be prepared according to the invention are, inter alia, starting materials for the preparation of plant protection agents or pharmaceuticals.

公开(公告)号：CA2080207A1

公开(公告)日：1993-04-10

申请号：CA2080207

申请日：1992-10-08

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  PRESSLER WILFRIED ,  RAPP JOCHEN

IPC: B01J23/04 ,  C07B61/00 ,  C07C201/12 ,  C07C205/37

Abstract: HOE 91/F 317 Process for the preparation of 1,2-bis-(2-nitrophenoxy)-ethane The present invention relates to a process for the preparation of 1,2-bis-(2-nitrophenoxy)-ethane, by reacting 1 mole of ethylene glycol with about 190 to about 250 mol% of 2-chloronitrobenzene at temperatures of about 40 to about 100 metal hydroxide in dimethylacetamide.