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公开(公告)号：BRPI0918317A2
公开(公告)日：2015-08-18
申请号：BRPI0918317
申请日：2009-12-25
Applicant: TORAY INDUSTRIES
Inventor： SAWAI KENJI , SAWAI HIDEKI , NAKAGAWA IZUMI , YAMADA KATSUSHIGE , KAWAMURA KENJI , ITO MASATERU , MINEGISHI SHIN-ICHI , MIMITSUKA TAKASHI , NAGANO TATSUYA
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公开(公告)号：AU2010319104B2
公开(公告)日：2015-05-07
申请号：AU2010319104
申请日：2010-11-10
Applicant: TORAY INDUSTRIES
Inventor： TAKEUCHI NORIHIRO , MINEGISHI SHIN-ICHI , CHEON JIHOON , NISHIDA MAKOTO , MIMITSUKA TAKASHI , SUZUKI HIRONOBU , YAMADA KATSUSHIGE , SAWAI HIDEKI , KUMO ICHIRO
Abstract: Disclosed is a hollow fiber membrane module (1) for use in the production of a chemical substance, which can be used in the continuous fermentation that comprises filtrating a fermentation culture of a microorganism or a cultured cell through a hollow fiber membrane, collecting a chemical substance from a filtrate, retaining a concentrated solution in the fermentation culture or refluxing the concentrated solution, and further adding a fermentation raw material to the fermentation culture. In the hollow fiber membrane module (1), multiple hollow fiber membrane bundles are accommodated in a tubular case, at least one end part of each of the hollow fiber membrane bundles is fixed onto the tubular case in such a manner that the end surface of each of the hollow fiber membranes is opened by means of a hollow-fiber-membrane-bundling material, and the hollow-fiber-membrane-bundling material comprises a synthetic resin that exhibits a hardness retention rate of 95% or more after the material is brought into contact with a saturated water vapor at 121°C for 24 hours. The hollow fiber membrane module (1) can keep substance productivity at a high level and can be used in the production of a chemical substance by a sterilizable continuous fermentation method.
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公开(公告)号：CA2916064A1
公开(公告)日：2014-12-31
申请号：CA2916064
申请日：2014-06-23
Applicant: TORAY INDUSTRIES
Inventor： MIMITSUKA TAKASHI , HAYAKAWA HIROSHI , MORITA KEN , YAMAMOTO YUKI , OTSUKA KENICHI
Abstract: This continuous sterilization device sterilizes a member constituting a flow path by causing a sterilization medium for sterilizing the member to flow through the member, causes a sterile liquid subjected to sterilization treatment to flow through a pipe, while performing a series of treatments including heat treatment, holding treatment, and cooling treatment on the sterile liquid, controls the flow rate, temperature, and pressure thereof to preset conditions, and switches a liquid to flow through the flow path from the sterile liquid to a liquid to be sterilized.
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公开(公告)号：ES2407639T3
公开(公告)日：2013-06-13
申请号：ES09708832
申请日：2009-02-03
Applicant: TORAY INDUSTRIES
Inventor： SASAKI NANAMI , MORITA KEN , MIMITSUKA TAKASHI , SAWAI HIDEKI , YAMADA KATSUSHIGE
Abstract: Un procedimiento para producir ácido láctico por fermentación continua, en el que el cultivo de levadura poliploide que tiene la capacidad de producir ácido láctico se filtra a través de una membrana porosa que tiene un tamaño de poro medio de un mínimo de 0,01 m y menos de 1 m y el producto se recupera a partir del filtrado, mientras que el líquido no filtrado se retiene o se reintroduce en el cultivo, y al cultivo se le añade una materia prima de fermentación.
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公开(公告)号：AU2007218753B2
公开(公告)日：2012-08-16
申请号：AU2007218753
申请日：2007-02-16
Applicant: TORAY INDUSTRIES
Inventor： SAWAI HIDEKI , ITO YOHITO , MIMITSUKA TAKASHI , YONEHARA TETSU , HENMI MASAHIRO , SAWAI KENJI , YAMADA KATSUSHIGE
IPC: C12P7/56 , C12M1/12 , C12N15/09 , C12P7/06 , C12P7/18 , C12P7/46 , C12P7/50 , C12P13/00 , C12P13/08 , C12P19/30
Abstract: A method of producing a chemical product via continuous fermentation, which comprises filtering a liquid culture medium of a microorganism or cultured cells through a separation membrane, collecting the product from the filtrate, keeping the unfiltered liquid in the liquid culture medium or refluxing thereinto and additionally supplying the material to be fermented into the liquid culture medium, wherein a porous membrane having an average pore size of 0.01 μm or more but less than 1 μm is employed as the separation membrane and the filtration is carried out at an intermembrane pressure difference of from 0.1 to 20 kPa. According to this method, the fermentation productivity of the chemical product can be largely elevated at high stability and a low cost.
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Patent Agency Ranking
公开(公告)号：CA2796363A1
公开(公告)日：2011-10-20
申请号：CA2796363
申请日：2011-04-11
Applicant: TORAY INDUSTRIES
Inventor： SAWAI KENJI , WATANABE SHIOMI , MIMITSUKA TAKASHI , SAWAI HIDEKI
IPC: C12P13/00 , C07C211/09 , C12N9/88 , C12N15/09
Abstract: Disclosed is a method for producing 1,5-pentanediamine through fermentation using a microorganism, said microorganism having LDC gene in the chromosome and showing regulated secondary production of L-lysine. In the method for producing 1,5-pentanediamine whereby 1,5-pentanediamine is produced by a coryneform bacterium having a gene encoding lysine decarboxylase in the chromosome, said coryneform bacterium continuously maintains a lysine decarboxylase activity of 50 mU/mg protein or greater during the culture.
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公开(公告)号：CA2748354A1
公开(公告)日：2010-07-01
申请号：CA2748354
申请日：2009-12-25
Applicant: TORAY INDUSTRIES
Inventor： SAWAI KENJI , SAWAI HIDEKI , MIMITSUKA TAKASHI , ITO MASATERU , YAMADA KATSUSHIGE , KAWAMURA KENJI , MINEGISHI SHIN-ICHI , NAKAGAWA IZUMI , NAGANO TATSUYA
Abstract: Disclosed is a method for producing lactic acid, which comprises (A) a continuous fermentation step wherein a fermentation broth of microorganisms which are capable of lactic acid fermentation is filtrated using a porous membrane having an average pore diameter of 0.01 µm or more but less than 1 µm with a transmembrane pressure difference within a range of 0.1-20 kPa; the filtrate is recovered, while holding or flowing back the unfiltrate to the broth; and a fermentation raw material is added to the broth; (B) a step wherein the filtrate obtained in step (A) is filtrated through a nano-filtration membrane; and (C) a step wherein lactic acid is recovered by distilling the filtrate obtained in step (B) at a pressure not less than 1 Pa but not more than the atmospheric pressure at a temperature not less than 25°C but not more than 200°C. Lactic acid obtained by the method has reduced impurities, and thus a polylactic acid obtained using the lactic acid as a starting material has excellent thermal stability, mechanical strength and hue.
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48.发明公开METHOD FOR PRODUCING CHEMICAL AND CONTINUOUS CULTURE SYSTEM 有权VERFAHREN ZUR HERSTELLUNG EINES KONTINUIERLICHEN CHEMISCHEN KULTURSYSTEMS
公开(公告)号：EP2330209A4
公开(公告)日：2015-04-01
申请号：EP09817650
申请日：2009-09-16
Applicant: TORAY INDUSTRIES
Inventor： MIMITSUKA TAKASHI , ISHII KENTARO , MORITA KEN , HIGASA MASASHI , SAWAI KENJI , SAWAI HIDEKI , YAMADA KATSUSHIGE , MINEGISHI SHINICHI
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公开(公告)号：EP2311969A4
公开(公告)日：2012-03-14
申请号：EP09708832
申请日：2009-02-03
Applicant: TORAY INDUSTRIES
Inventor： SASAKI NANAMI , MORITA KEN , MIMITSUKA TAKASHI , SAWAI HIDEKI , YAMADA KATSUSHIGE
CPC classification number: C12P7/56
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公开(公告)号：EP2540836A4
公开(公告)日：2015-02-11
申请号：EP11747305
申请日：2011-02-22
Applicant: TORAY INDUSTRIES
Inventor： MIMITSUKA TAKASHI , SUDA KAZUMI , SAWAI HIDEKI
CPC classification number: C12P13/001 , C07K2319/02 , C12N9/88
Abstract: By a method for producing cadaverine by culturing a microorganism that extracellularly secretes lysine decarboxylase, by-production of lysine is suppressed, the yield of cadaverine relative to glucose consumption is improved compared to conventional production methods, and further, the load on the purification step in purification of cadaverine as a raw material for polyamide can be reduced.
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