公开(公告)号：EP3123501A4

公开(公告)日：2017-11-08

申请号：EP15768284

申请日：2015-03-25

Applicant: KLA-TENCOR CORP

Inventor： HORN PAUL

IPC: H01L21/66 ,  G01B11/24 ,  G01B11/30 ,  G01N21/88 ,  G01N21/95

CPC classification number: G01N21/8851 ,  G01N21/8806 ,  G01N21/9501 ,  G01N2201/06113 ,  G01N2201/105 ,  H01L22/12

公开(公告)号：EP3180465A4

公开(公告)日：2017-08-30

申请号：EP15847665

申请日：2015-09-16

Applicant: SRI INT INC

Inventor： COLLINS NATHAN ,  MADRID PETER

IPC: C40B40/14 ,  C08G69/36 ,  C40B50/14 ,  C40B60/12 ,  G01N21/64 ,  G01N33/543 ,  G01N33/68

CPC classification number: G01N33/6848 ,  B01J2219/0045 ,  B01J2219/00576 ,  B01J2219/00596 ,  B01J2219/00675 ,  B01J2219/00702 ,  C07B2200/11 ,  C08G69/36 ,  C40B40/14 ,  C40B50/14 ,  C40B60/12 ,  G01N21/6456 ,  G01N33/54313 ,  G01N2201/08 ,  G01N2201/105 ,  G01N2201/12 ,  G01N2560/00

Abstract: Devices, systems and methods for affinity reagent and catalyst discovery employing a library on a bead HTS platform, each bead comprising affixed non-natural polymers of a distinct bioactive monomer with sequence pre-defined branching and folding in tertiary structures, and fiber-optic array scanning technology.

Abstract translation: 在珠HTS平台上使用文库的亲和试剂和催化剂发现的装置，系统和方法，每个珠包含固定的具有序列预定义的分支和折叠的三维结构的不同生物活性单体的非天然聚合物，以及纤维光学阵列 扫描技术。

公开(公告)号：EP3105567A1

公开(公告)日：2016-12-21

申请号：EP15748568.1

申请日：2015-02-13

Applicant: Hager Environmental and Atmospheric Technologies, LLC

Inventor： HAGER, J. Stewart ,  YEREM, Geoffrey

IPC: G01N21/49 ,  G01N21/39 ,  G01K11/32

CPC classification number: G01N21/39 ,  G01K11/00 ,  G01N2021/1793 ,  G01N2021/399 ,  G01N2201/105

Abstract: Aspects of the invention are directed to a device and method for detecting characteristics of a gas. The gas includes an exhausted plume from a vehicle or factory plant, leaked gas from an oil well or gas resource, or unidentified gas from an unknown source. The method includes sweepingly directing a beam of light through the gas to a target surface on which the beam of light is scattered, acquiring the scattered light scattered from the target surface, and processing the acquired scattered light to determine the characteristics of the gas, where the characteristics of the gas comprise at least one of a temperature of the gas and an amount of at least one ingredient of the gas.

公开(公告)号：EP2953215A1

公开(公告)日：2015-12-09

申请号：EP14192304.5

申请日：2014-11-07

Applicant: Ludwig-Maximilians-Universität München

Inventor： Huber, Robert Alexander ,  Karpf, Sebastian ,  Eibl, Matthias

IPC: H01S3/10 ,  H01S3/30 ,  H01S3/094

CPC classification number: G01N21/6456 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/65 ,  G01N2021/6484 ,  G01N2201/06146 ,  G01N2201/0635 ,  G01N2201/105 ,  G01N2201/11 ,  G01N2201/12 ,  H01S3/06712 ,  H01S3/06754 ,  H01S3/094007 ,  H01S3/10015 ,  H01S3/1618 ,  H01S3/2316 ,  H01S3/302 ,  H01S2301/02

Abstract: Described is a system for inducing and detecting multi-photon processes, in particular multi-photon fluorescence or higher harmonic generation in a sample. The system comprises a dynamically-controllable light source, said dynamically-controllable light source comprising a first sub-light source, said first sub-light source being electrically controllable such as to generate controllable time-dependent intensity patterns of light having a first wavelength, and at least one optical amplifier, thereby allowing for active time-control of creation of multi-photon-excitation. The system further comprises a beam delivery unit for delivering light generated by said dynamically-controllable light source to a sample site, and a detector unit or detector assembly for detecting signals indicative of said multi-photon process, in particular multi-photon fluorescence signals or higher harmonics signals.

Abstract translation: 描述了用于诱导和检测多光子过程，特别是样品中的多光子荧光或更高次谐波产生的系统。 该系统包括动态可控光源，所述动态可控光源包括第一子光源，所述第一子光源是电可控制的，以便产生具有第一波长的光的可控时间依赖强度图案， 和至少一个光放大器，从而允许对多光子激发的产生的主动时间控制。 该系统还包括用于将由所述动态可控光源产生的光传送到采样点的光束传送单元，以及用于检测指示所述多光子过程，特别是多光子荧光信号的信号的检测器单元或检测器组件， 高次谐波信号。

公开(公告)号：EP2792295A4

公开(公告)日：2015-09-09

申请号：EP12858271

申请日：2012-12-17

Applicant: RIKEN

Inventor： WADA SATOSHI ,  TSUBOTA KAZUO ,  SHINJO ATSUSHI

IPC: A61B3/10 ,  A61B3/12 ,  A61B5/00 ,  G01N21/65

CPC classification number: A61B5/1455 ,  A61B3/1025 ,  A61B3/12 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/14546 ,  G01N21/65 ,  G01N2021/5957 ,  G01N2021/653 ,  G01N2201/06113 ,  G01N2201/105

公开(公告)号：EP2821779A1

公开(公告)日：2015-01-07

申请号：EP13769735.5

申请日：2013-03-15

Applicant: Sanyo Electric Co., Ltd. ,  Panasonic Corporation

Inventor： MATSUMURA Yoshiyuki ,  NAGATOMI Kenji ,  NAKATANI Masaya ,  OKI Akio ,  NAKATANI Morio ,  HAYASHI Takuya ,  HAYAMA Masaaki

IPC: G01N21/64 ,  G01N21/03

CPC classification number: G01N21/645 ,  B01L3/5085 ,  B01L2300/024 ,  B01L2300/0654 ,  B01L2300/0803 ,  B01L2300/0806 ,  B01L2300/0819 ,  B01L2300/0893 ,  B01L2300/168 ,  G01N21/03 ,  G01N21/6447 ,  G01N21/6452 ,  G01N35/00069 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2201/105 ,  G11B7/00 ,  G11B7/09

Abstract: The present invention provides a sample holding carrier that can accurately measure a sample with a simple configuration, and a fluorescence detection system and a fluorescence detection device that use the same. Biosensor substrate (10) includes: base substrate (11) on which excitation light is incident from a lower surface; reflecting film (14) that is arranged on an upper surface of base substrate (11) to partially reflect the excitation light; and plural wells (13) that are arranged on an upper surface side of reflecting film (14) and have bottom surface portions (13a). The excitation light is converged to be incident on base substrate (11). Distance d3 from reflecting surface (11a) that is of a boundary between reflecting film (14) and base substrate (11) to bottom surface portion (13a) of well (13) is less than or equal to a focal depth of the excitation light. Therefore, the sample accommodated in bottom surface portion (13a) of well (13) can surely and efficiently be irradiated with the excitation light, and accurately be measured.

Abstract translation: 本发明提供一种能够以简单的结构精确测量样品的样品保持载体和使用其的荧光检测系统和荧光检测装置。 生物传感器基板（10）包括：基底基板（11），激光从下表面入射; 反射膜（14），其布置在基底（11）的上表面上以部分地反射激发光; 以及设置在反射膜（14）的上表面侧并具有底面部（13a）的多个孔（13）。 激发光会聚到入射到基底（11）上。 与反射膜（14）和基板（11）之间的边界的反射面（11a）到阱（13）的底面部（13a）的距离d3小于或等于激发光的焦深 。 因此，容纳在井（13）的底面部（13a）中的样品能够可靠且有效地用激发光照射，并且被精确地测量。

公开(公告)号：EP2181321A4

公开(公告)日：2011-10-19

申请号：EP08793215

申请日：2008-08-13

Applicant: KOREA RES INST OF BIOSCIENCE

Inventor： CHUNG BONG HYUN ,  SHIN YONG BEOM

IPC: G01N21/55 ,  G02B26/10

CPC classification number: G01N21/553 ,  G01N21/7743 ,  G01N2201/0636 ,  G01N2201/105 ,  G02B5/008

公开(公告)号：EP1691189A3

公开(公告)日：2010-12-01

申请号：EP06101473.4

申请日：2006-02-09

Applicant: Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd.)

Inventor： TAKAHASHI, Eiji ,  TAKAMATSU, Hiroyuki ,  KANNAKA, Masato ,  SAKODA, Naokazu ,  MORIMOTO, Tsutomu

IPC: G01N21/17 ,  G01N21/03

CPC classification number: G01N21/171 ,  G01N21/031 ,  G01N2021/1712 ,  G01N2021/178 ,  G01N2201/105

Abstract: A liquid sample is irradiated with excitation light and measurement light, and a measurement position at which a traveling path of the measurement light passes through an excitation section of the excitation light in the sample is changed while the sample is being irradiated with the excitation light and the measurement light. Then, the phase change of the measurement light is measured for each measurement by optical interferometry on the basis of the measurement light after the measurement light passes through the sample. The measurement position is changed by, for example, scanning the excitation light, moving the sample, moving a lens that collects the excitation light in the sample so as to change the light-collecting position (focal position) in the sample, etc.

公开(公告)号：EP2243008A1

公开(公告)日：2010-10-27

申请号：EP09704541.3

申请日：2009-01-26

Applicant: Renishaw PLC

Inventor： HAYWARD, Ian, Paul ,  SMITH, Brian, John, Edward

IPC: G01J3/44 ,  G01J3/28 ,  G01N21/65 ,  G01J3/02

CPC classification number: G01J3/02 ,  G01J3/0289 ,  G01J3/44 ,  G01N21/65 ,  G01N2021/656 ,  G01N2201/103 ,  G01N2201/105

Abstract: In a Raman spectroscopy apparatus, exciting light is focussed on a sample (26) as a line focus (38). Spectra from points in the line focus are dispersed in rows 46 on a CCD detector (34), having a two-dimensional array of pixels. The line focus moves longitudinally in a direction Y relative to the sample. Simultaneously and synchronously, charge is shifted in a parallel direction Y' within the CCD, so that data from a given point in the sample continues to accumulate, hi order to provide averaging in the X direction during fast, low resolution scanning, the line focus is swept across the sample in a zig-zag fashion, between boundary lines 60.

公开(公告)号：JP2017535517A

公开(公告)日：2017-11-30

申请号：JP2017514916

申请日：2015-09-16

Applicant: エスアールアイ インターナショナルSRI International ,  エスアールアイ インターナショナルSRI International

Inventor： コリンズ，ネイサン ,  マドリード，ピーター

IPC: C40B40/10 ,  G01N21/64 ,  G01N21/78 ,  G01N27/62 ,  G01N33/15 ,  G01N37/00

CPC classification number: G01N33/6848 ,  B01J2219/0045 ,  B01J2219/00576 ,  B01J2219/00596 ,  B01J2219/00675 ,  B01J2219/00702 ,  C07B2200/11 ,  C08G69/36 ,  C40B40/14 ,  C40B50/14 ,  C40B60/12 ,  G01N21/6456 ,  G01N33/54313 ,  G01N2201/08 ,  G01N2201/105 ,  G01N2201/12 ,  G01N2560/00

Abstract: ビーズHTSプラットフォーム上のライブラリおよび光ファイバーアレイ走査技術を使用した、親和性試薬および触媒を発見するためのデバイス、システム、および方法であって、各ビーズが、分岐および三次構造への折り畳みが事前に規定されている配列を有する特徴的な生物活性モノマーの結合非天然ポリマーを含むデバイス、システム、および方法。【選択図】図1