Abstract:
PURPOSE: A cosmetic composition containing Rubus coreanus extract is provided to suppress formation of SNARE complex and to improve anti-wrinkling. CONSTITUTION: A cosmetic composition for improving anti-wrinkling contains 0.0001-30 weight% of Rubus coreanus extract as an active ingredient. The Rubus coreanus extract is obtained from fruit of Rubus coreanus Miquel using 80% ethanol. The Rubus coreanus is pretreated by steaming at 120-150°C for 3-6 hours, roasting at 100-180°C for 10 minutes to one hour and 80-100°C for 10 minutes to one hour.
Abstract:
PURPOSE: A skin external composition for preventing or treating inflammatory dermatitis containing natural products is provided to ensure anti-inflammation and skin moisturization. CONSTITUTION: A skin external composition for preventing or treating inflammatory dermatitis contains 0.001-20 weight% of green tea, 0.05-3 weight% of sophora root, 0.05-3 weight% of Portulaca oleracea L., and 0.5-30 weight% of Polygonatum officinale as active ingredient. The skin external composition additionally contains 1-50 weight% of starch, 1-10 weight% of cacao bean, 1-10 weight% of Cnidii Rhizoma or 0.5-5 weight% of Angelicae gigantis Radix. The composition is cosmetic composition or pharmaceutical composition.
Abstract:
A composition for external application for treating and preventing the pruritus or irritant skin disease is provided to have excellent fluxes and stability by containing the thiourea derivative and to be useful in pruritus or irritant skin disease. A composition for external application of O/w-shaped emulsion form comprises (1) drug expressed as a compound of a chemical formula 1, (2) a component selected from a group consisting of squalene, dimethicone, propylene glycol, butylene glycol and mineral oil, (3) a component selected from a group consisting of polyethylene glycol 400, polyoxyethylene alkyl ether, cetyl alcohol and solbitan stearate, (4) water and (5) a component selected from a group consisting of ethanol, twin 60, carbomer 940, EDTA.2Na and triethanolammine.
Abstract:
Provided are a 2-cyclopenten-1-one oxime derivative which inhibits the production of TNF-alpha or PEF4, its pharmaceutically acceptable salt, and a pharmaceutical composition containing the derivative for treating or preventing the TNF-alpha mediated disease. A 2-cyclopenten-1-one oxime derivative is represented by the formula(1), wherein R1 is a linear or branched C1-C10 alkyl group or a C3-C7 cycloalkyl group; and R2 is a substituted or unsubstituted aromatic group. Preferably the aromatic group of R2 is selected from a phenyl group, a pyridyl group, a naphthyl group, an indolyl group, a thienyl group, a benzo[b]thienyl group, a dibenzofuranyl group, or a thianthrenyl group.
Abstract:
본 발명은 바닐로이드 수용체(Vanilloid Receptor; VR)에 대한 조절제로서 신규한 티오우레아 유도체를 함유하는 약제학적 조성물에 관한 것이다. 바닐로이드 수용체의 활성과 연관된 질환에는 통증, 급성 통증, 만성 통증, 신경병적 통증, 수술후 통증, 편두통, 관절통, 신경병증, 신경손상, 당뇨병성 신경병, 신경변성 질환, 신경성 피부질환, 뇌졸중, 방광과민증, 과민성 장증후군, 천식과 만성폐색성 폐질환등 호흡기 이상, 피부, 눈, 점막의 자극, 발열, 위-십이지장궤양, 염증성 장 질환 및 염증성 질환 등이 포함될 수 있다. 본 발명은 이들 질환의 예방, 치료를 위한 약제학적 조성물을 제공한다.
Abstract:
본발명은중공관형태의관통구를포함하는침관, 상기침관이고정되는구멍을포함하는침기및 상기침관을관통하여침관의선단부에서봉합사를끼우기위한고리를형성하고실 양쪽끝단이침관의후단부로빠져나온유도실을포함하는피부시술도구및 키트에관한것이다. 본발명은봉합사를유도실이형성하는고리에끼움으로써, 침관의두께에영향받지않고다양한굵기또는형태를갖는봉합사의사용이가능하며, 종래두꺼운굵기의침관으로인해발생했던부작용을감소시키고피부시술효과를증대시킬수 있다. 또한, 유도실양쪽끝단을침관후단부로빠져나오게하여유도실고정부또는유도실고정덮개로고정함으로써피부시술시실밀림을방지할수 있다.
Abstract:
본 명세서는 글루코스아미노글라이칸의 하나인 콘드로이친설페이트와 히알루론산을 함유하는 콜라겐의 생성을 촉진하는 조성물에 관한 것으로서, 피부 조직에 처리하였을 때 뛰어난 콜라겐 생성 효과를 나타내고, 피부 조직을 수복시키는 것을 촉진 하는 조성물에 관한 것이다.
Abstract:
PURPOSE: A lipolysis kit is provided to alleviate pain, bruise, red spots, edema, pruritus, etc. which are caused by a lipolysis shot by having injection liquid containing a low frequency stimulator and a lipolysis material. CONSTITUTION: A lipolysis kit comprises a lipolysis material and a low frequency stimulator. A lipolysis means includes a composition for lipolysis, and a transfer mechanism to transfer the composition for lipolysis to a target area. The composition for lipolysis includes at least one or more of lipid, bile acid or salt thereof, a beta adrenalin receptor effector, and hyaluronidase. The composition for lipolysis contains at least one or more of deoxycholic acid, cholic acid, chenodeoxycholic acid, 7-alpha-dehydroxylate chenodeoxycholic acid, litho cholic acid, ursodeoxycholic acid, dihydroxy taurine acid, trihydroxy taurine acid or salt thereof, phosphatidylcholine, hyaluronidase, aminophylline, theophylline, isoproterenol, and salbutamol and salmeterol or salt thereof. The transfer mechanism includes at least one of a syringe containing one needle, a syringe containing multiple needles, a patch, and a micro needle. [Reference numerals] (AA) Δupper arm girth(cm); (BB) PPC + low frequency wave; (CC) 50% improvement; (DD) -after 2-3 days, measurement of upper arm girth