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    아이오논(ionone) 유도체 화합물
    54.
    发明公开
    아이오논(ionone) 유도체 화합물 审中-实审
    离子衍生物化合物

    公开(公告)号：KR1020150062443A

    公开(公告)日：2015-06-08

    申请号：KR1020130147098

    申请日：2013-11-29

    Applicant: (주)아모레퍼시픽

    Inventor： 최수정 ,  주영협 ,  우병영 ,  김혁 ,  한지원 ,  백흥수 ,  신송석 ,  박영호

    IPC: C07C235/24 ,  A61K31/166 ,  A61P17/18

    Abstract: 본발명은일측면에서아이오논유도체화합물, 이의이성질체, 이의약학적으로허용가능한염, 이의프로드럭, 이의수화물또는이의용매화물에관한것이다. 본발명은다른일측면에서아이오논유도체화합물, 이의이성질체, 이의약학적으로허용가능한염, 이의프로드럭, 이의수화물또는이의용매화물을포함하는피부노화방지용조성물에관한것이다.

    Abstract translation: 本发明的一个方面涉及紫罗兰酮衍生物化合物，其异构体，其异构体，其药学上可接受的盐，其前体药物，其水合物或其溶剂合物。 本发明的另一方面涉及一种用于防止皮肤老化的组合物，其中紫罗兰酮衍生物化合物，其异构体，其药学上可接受的盐，其前药，其水合物或 包括其中的溶剂合物。

    신규 페닐초산 아미드 유도체 화합물
    55.
    发明公开
    신규 페닐초산 아미드 유도체 화합물 审中-实审
    新颖的苯甲酸衍生化合物

    公开(公告)号：KR1020140117842A

    公开(公告)日：2014-10-08

    申请号：KR1020130032634

    申请日：2013-03-27

    Applicant: (주)아모레퍼시픽

    Inventor： 조영석 ,  주영협 ,  우병영 ,  이창석 ,  최수정 ,  백흥수 ,  신송석 ,  박영호

    IPC: C07C233/05 ,  A61K31/165 ,  A61P17/16

    Abstract: The present invention relates to a novel phenylacetic acid amide derivative compound, isomers thereof, pharmaceutically acceptable salt thereof, prodrug thereof, a hydrate or a solvate thereof, and a composition for skin whitening comprising the same. The novel compound or the like has excellent skin whitening effect.

    Abstract translation: 本发明涉及一种新的苯乙酸酰胺衍生物化合物，其异构体，其药学上可接受的盐，其前体药物，其水合物或溶剂合物，以及包含其的皮肤美白组合物。 新颖的化合物等具有优异的皮肤美白效果。

    신규한 유사 세라마이드 화합물 및 그 제조방법
    56.
    发明公开
    신규한 유사 세라마이드 화합물 및 그 제조방법 审中-实审
    新型PSEUDO-CERAMIDE化合物及其制备方法

    公开(公告)号：KR1020140069931A

    公开(公告)日：2014-06-10

    申请号：KR1020120137822

    申请日：2012-11-30

    Applicant: (주)아모레퍼시픽

    Inventor： 주영협 ,  백흥수 ,  우병영 ,  최수정 ,  장원희 ,  박양희 ,  신송석 ,  박영호

    IPC: C07C233/09 ,  C07C233/02

    Abstract: The present invention provides a novel pseudo-ceramide compound represented by Chemical Formula 1, an isomer thereof, a pharmaceutically acceptable salt thereof, a pro-drug thereof, a hydrate thereof, and a solvate thereof. [Chemical Formula 1] (In Chemical Formula 1, R is a C9 to 17 saturated or unsaturated aliphatic chain, and R′ is an amino group or an alkoxy group having a C10 to 18 saturated aliphatic chain.) According to the present invention, the novel pseudo-ceramide compound has a skin protecting effect by having excellent stability, dissolubility, and skin moisturization, so that the novel pseudo-ceramide compound can be used as an active ingredient for protecting the skin from external stimuli without side effects, preventing the skin from damage, and recovering damaged skin. Accordingly, the novel pseudo-ceramide compound can be used as a skin-moisturizing composition for external application on skin, a cosmetic composition, or a pharmaceutical composition.

    Abstract translation: 本发明提供由化学式1表示的新型假神经酰胺化合物，其异构体，药学上可接受的盐，其前体药物，其水合物及其溶剂合物。 [化学式1]（化学式1中，R为C 9〜17饱和或不饱和脂肪族链，R'为氨基或碳原子数为10〜18的饱和脂肪族链的烷氧基。）根据本发明， 新型伪神经酰胺化合物通过具有优异的稳定性，溶解性和皮肤保湿性而具有皮肤保护效果，因此新颖的假神经酰胺化合物可以用作保护皮肤免受外部刺激的活性成分而没有副作用，从而防止 皮肤受损，并恢复受损皮肤。 因此，新颖的假神经酰胺化合物可以用作皮肤外用的皮肤保湿组合物，化妆品组合物或药物组合物。

    신규 벤조산아미드 화합물
    57.
    发明公开
    신규 벤조산아미드 화합물 有权
    新颖的苯甲酸化合物

    公开(公告)号：KR1020130015954A

    公开(公告)日：2013-02-14

    申请号：KR1020110078309

    申请日：2011-08-05

    Applicant: (주)아모레퍼시픽

    Inventor： 주영협 ,  백흥수 ,  이창석 ,  최수정 ,  노호식 ,  박미영 ,  신송석 ,  임경민 ,  박영호

    IPC: C07C235/46 ,  C07C235/48 ,  A61K8/42 ,  A61Q19/02

    CPC classification number: A61K8/42 ,  A61Q19/00 ,  A61Q19/02 ,  C07C235/46 ,  C07C235/48 ,  C07C2603/74

    Abstract: PURPOSE: A benzoic acid amide compound is provided to have excellent a skin-whitening effect without side effects by suppressing melanin generation and decreasing tyrosinase activity. CONSTITUTION: A benzoic acid amide compound, an isomer thereof, pharmaceutically-acceptable salt thereof, a prodrug thereof, a hydrate thereof, or a solvate thereof is represented by chemical formula 1. In the chemical formula 1: each of R1, R3, and R4 is independently selected from hydrogen, hydroxy, C1-C5 alkoxy, C3-C6 cycloalkoxy, aryloxy, and C1-C15 haloalkoxy; R2 is selected from hydrogen, C1-C5 alkyl, C3-C6 cycloalkyl, aryl, and C1-C5 haloalkyl; and n is an integer from 1-5.

    Abstract translation: 目的：提供苯甲酸酰胺化合物以通过抑制黑色素产生和降低酪氨酸酶活性而具有优异的美白效果而没有副作用。 构成：化学式1表示苯甲酸酰胺化合物，其异构体，药学上可接受的盐，其前药，其水合物或其溶剂合物。在化学式1中，R1，R3和 R 4独立地选自氢，羟基，C 1 -C 5烷氧基，C 3 -C 6环烷氧基，芳氧基和C 1 -C 15卤代烷氧基; R2选自氢，C1-C5烷基，C3-C6环烷基，芳基和C1-C5卤代烷基; n为1-5的整数。

    유색콩 추출물을 함유하는 조성물
    58.
    发明公开
    유색콩 추출물을 함유하는 조성물 无效
    包含色素提取物的组合物

    公开(公告)号：KR1020110138000A

    公开(公告)日：2011-12-26

    申请号：KR1020100058067

    申请日：2010-06-18

    Applicant: (주)아모레퍼시픽

    Inventor： 김진관 ,  김채욱 ,  정연수 ,  윤준원 ,  임경민 ,  주영협 ,  박영호 ,  신현정

    IPC: A61K36/48 ,  A61P7/02 ,  A61P7/00

    CPC classification number: A61K36/48

    Abstract: PURPOSE: An antithrombotic composition containing colored bean extract and fraction thereof is provided to contain adenosine and to treat cardiovascular and cerebralvascular diseases and hypertension. CONSTITUTION: An antithrombotic composition contains colored bean extract isolated using water, C1-C5 alcohol, or mixture thereof and organic acid. The organic acid includes citric acid, acetic acid, butyric acid, palmitic acid, oxalic acid, tartaric acid, carboxylic acid, or sulfonic acid. The C1-C5 alcohol is methane, ethanol, isopropylalcohol, n-propyl alcohol, n-butanol, or isobutanol. A fraction of the extract is prepared by fractioning the alcohol extract of colored beans using a synthetic adsorption column containing polystylene and benzene polymers.

    Abstract translation: 目的：提供含有彩色豆提取物及其级分的抗血栓形成组合物，用于含有腺苷并治疗心血管和脑血管疾病和高血压。 构成：抗血栓组合物含有使用水，C1-C5醇或其混合物和有机酸分离的有色豆提取物。 有机酸包括柠檬酸，乙酸，丁酸，棕榈酸，草酸，酒石酸，羧酸或磺酸。 C1-C5醇是甲烷，乙醇，异丙醇，正丙醇，正丁醇或异丁醇。 通过使用含有聚苯乙烯和苯聚合物的合成吸附塔对有色豆的醇提取物进行分级来制备提取物的一部分。

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