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公开(公告)号：KR1020110007540A
公开(公告)日：2011-01-24
申请号：KR1020090065107
申请日：2009-07-16
Applicant: (주)아모레퍼시픽
IPC: A61K8/49 , A61Q19/08 , A61K31/352 , A61P17/18
CPC classification number: A61K8/498 , A61K8/418 , A61K8/466 , A61K2800/522 , A61Q19/08
Abstract: PURPOSE: A composition for skin anti-aging is provided to suppress matrix metalloprotease activation without skin irritation. CONSTITUTION: A composition for skin anti-aging contains 0.01-20 weight% of compound of chemical formula 1, isomer or pharmaceutically acceptable salt thereof as an active ingredient. The composition is used for preventing or treating wrinkling and skin aging. The composition is a pharmaceutical composition or cosmetic composition. The pharmaceutical composition is manufactured in the form of lotion, ointment, gel, cream, patch or spray. The cosmetic composition is used in the form of essence, nutrition cream, massage cream, pack, gel, essence, eye cream, cleansing cream, cleansing foam, pack, and powder.
Abstract translation: 目的：提供皮肤抗衰老的组合物，以抑制基质金属蛋白酶活化而无皮肤刺激。 构成：用于皮肤抗衰老的组合物含有0.01-20重量％的化学式1的化合物，其异构体或其药学上可接受的盐作为活性成分。 该组合物用于预防或治疗皱纹和皮肤老化。 该组合物是药物组合物或化妆品组合物。 药物组合物以洗剂，软膏，凝胶，霜剂，贴剂或喷雾剂的形式制备。 化妆品组合物以精华，营养霜，按摩霜，包装，凝胶，精华，眼霜，清洁霜，清洁泡沫，包装和粉末的形式使用。
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公开(公告)号：KR1020050090356A
公开(公告)日：2005-09-13
申请号：KR1020050078835
申请日：2005-08-26
Applicant: (주)아모레퍼시픽
Inventor： 서영거 , 오우택 , 김희두 , 이지우 , 박형근 , 박옥희 , 이용실 , 박영호 , 주영협 , 최진규 , 임경민 , 김선영 , 김진관 , 고현주 , 모주현 , 정연수 , 이정범 , 오영임
IPC: A61K31/17
CPC classification number: C07D333/42 , C07C311/08 , C07C311/47 , C07C333/20 , C07C335/12 , C07C335/14 , C07C335/20 , C07C335/26 , C07C2601/14 , C07C2602/10 , C07D207/323 , C07D207/416 , C07D207/42 , C07D209/08 , C07D209/14 , C07D213/40 , C07D213/61 , C07D213/76 , C07D217/06 , C07D231/14 , C07D231/56 , C07D233/64 , C07D235/14 , C07D239/42 , C07D241/12 , C07D241/24 , C07D277/28 , C07D295/13 , C07D295/215 , C07D295/32 , C07D307/52 , C07D311/58 , C07D317/58 , C07D333/20
Abstract: 본 발명은 바닐로이드 수용체(Vanilloid Receptor; VR)에 대한 조절제로서 신규한 티오우레아 유도체를 함유하는 약제학적 조성물에 관한 것이다.
바닐로이드 수용체의 활성과 연관된 질환에는 통증, 급성 통증, 만성 통증, 신경병적 통증, 수술후 통증, 편두통, 관절통, 신경병증, 신경손상, 당뇨병성 신경병, 신경변성 질환, 신경성 피부질환, 뇌졸중, 방광과민증, 과민성 장증후군, 천식과 만성폐색성 폐질환등 호흡기 이상, 피부, 눈, 점막의 자극, 발열, 위-십이지장궤양, 염증성 장 질환 및 염증성 질환 등이 포함될 수 있다. 본 발명은 이들 질환의 예방, 치료를 위한 약제학적 조성물을 제공한다.-
公开(公告)号：KR101932246B1
公开(公告)日：2018-12-21
申请号：KR1020160182547
申请日：2016-12-29
Applicant: (주)아모레퍼시픽
IPC: A61K36/48 , A23L33/105
Abstract: 본 발명은 유색콩 등으로부터 추출한 유색콩 추출물 및 그 분획물을 유효성분으로 함유하는 항혈전 효능 조성물에 관한 것이다. 본 발명에 의한 항혈전 조성물은 아데노신을 포함하고 있으며, 혈전 형성의 원인이 되는 심장혈관질환, 뇌혈관질환, 동맥경화증, 고혈압, 당뇨 등의 순환기계 질환의 치료에 매우 유용하게 이용될 수 있다.
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公开(公告)号：KR1020170004937A
公开(公告)日：2017-01-11
申请号：KR1020160182547
申请日：2016-12-29
Applicant: (주)아모레퍼시픽
IPC: A61K36/48 , A23L33/105
Abstract: 본발명은유색콩등으로부터추출한유색콩추출물및 그분획물을유효성분으로함유하는항혈전효능조성물에관한것이다. 본발명에의한항혈전조성물은아데노신을포함하고있으며, 혈전형성의원인이되는심장혈관질환, 뇌혈관질환, 동맥경화증, 고혈압, 당뇨등의순환기계질환의치료에매우유용하게이용될수 있다.
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公开(公告)号：KR1020170003387A
公开(公告)日：2017-01-09
申请号：KR1020160067409
申请日：2016-05-31
Applicant: (주)아모레퍼시픽
IPC: C07C231/02 , C07C231/08 , C07C233/64 , C07C233/75 , A61K8/44 , A61Q19/02
CPC classification number: C07C231/02 , C07C213/02 , C07C249/08 , C07C2603/74 , C07C235/60 , C07C217/58 , C07C251/48
Abstract: 본발명은반응물질로사용하는벤질아민화합물의새로운제조방법을제시하고, 이를이용하여각 단계의반응조건을한정함으로써고수율로벤조산아미드화합물의제조방법에관한것으로, 이러한방법은대량생산이가능하여경제적인측면에서유리하다.
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Patent Agency Ranking
公开(公告)号：KR1020150062443A
公开(公告)日：2015-06-08
申请号：KR1020130147098
申请日：2013-11-29
Applicant: (주)아모레퍼시픽
IPC: C07C235/24 , A61K31/166 , A61P17/18
Abstract: 본발명은일측면에서아이오논유도체화합물, 이의이성질체, 이의약학적으로허용가능한염, 이의프로드럭, 이의수화물또는이의용매화물에관한것이다. 본발명은다른일측면에서아이오논유도체화합물, 이의이성질체, 이의약학적으로허용가능한염, 이의프로드럭, 이의수화물또는이의용매화물을포함하는피부노화방지용조성물에관한것이다.
Abstract translation: 本发明的一个方面涉及紫罗兰酮衍生物化合物，其异构体，其异构体，其药学上可接受的盐，其前体药物，其水合物或其溶剂合物。 本发明的另一方面涉及一种用于防止皮肤老化的组合物，其中紫罗兰酮衍生物化合物，其异构体，其药学上可接受的盐，其前药，其水合物或 包括其中的溶剂合物。
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公开(公告)号：KR1020140117842A
公开(公告)日：2014-10-08
申请号：KR1020130032634
申请日：2013-03-27
Applicant: (주)아모레퍼시픽
IPC: C07C233/05 , A61K31/165 , A61P17/16
Abstract: The present invention relates to a novel phenylacetic acid amide derivative compound, isomers thereof, pharmaceutically acceptable salt thereof, prodrug thereof, a hydrate or a solvate thereof, and a composition for skin whitening comprising the same. The novel compound or the like has excellent skin whitening effect.
Abstract translation: 本发明涉及一种新的苯乙酸酰胺衍生物化合物，其异构体，其药学上可接受的盐，其前体药物，其水合物或溶剂合物，以及包含其的皮肤美白组合物。 新颖的化合物等具有优异的皮肤美白效果。
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公开(公告)号：KR1020140069931A
公开(公告)日：2014-06-10
申请号：KR1020120137822
申请日：2012-11-30
Applicant: (주)아모레퍼시픽
IPC: C07C233/09 , C07C233/02
Abstract: The present invention provides a novel pseudo-ceramide compound represented by Chemical Formula 1, an isomer thereof, a pharmaceutically acceptable salt thereof, a pro-drug thereof, a hydrate thereof, and a solvate thereof. [Chemical Formula 1] (In Chemical Formula 1, R is a C9 to 17 saturated or unsaturated aliphatic chain, and R′ is an amino group or an alkoxy group having a C10 to 18 saturated aliphatic chain.) According to the present invention, the novel pseudo-ceramide compound has a skin protecting effect by having excellent stability, dissolubility, and skin moisturization, so that the novel pseudo-ceramide compound can be used as an active ingredient for protecting the skin from external stimuli without side effects, preventing the skin from damage, and recovering damaged skin. Accordingly, the novel pseudo-ceramide compound can be used as a skin-moisturizing composition for external application on skin, a cosmetic composition, or a pharmaceutical composition.
Abstract translation: 本发明提供由化学式1表示的新型假神经酰胺化合物，其异构体，药学上可接受的盐，其前体药物，其水合物及其溶剂合物。 [化学式1]（化学式1中，R为C 9〜17饱和或不饱和脂肪族链，R'为氨基或碳原子数为10〜18的饱和脂肪族链的烷氧基。）根据本发明， 新型伪神经酰胺化合物通过具有优异的稳定性，溶解性和皮肤保湿性而具有皮肤保护效果，因此新颖的假神经酰胺化合物可以用作保护皮肤免受外部刺激的活性成分而没有副作用，从而防止 皮肤受损，并恢复受损皮肤。 因此，新颖的假神经酰胺化合物可以用作皮肤外用的皮肤保湿组合物，化妆品组合物或药物组合物。
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公开(公告)号：KR1020130015954A
公开(公告)日：2013-02-14
申请号：KR1020110078309
申请日：2011-08-05
Applicant: (주)아모레퍼시픽
IPC: C07C235/46 , C07C235/48 , A61K8/42 , A61Q19/02
CPC classification number: A61K8/42 , A61Q19/00 , A61Q19/02 , C07C235/46 , C07C235/48 , C07C2603/74
Abstract: PURPOSE: A benzoic acid amide compound is provided to have excellent a skin-whitening effect without side effects by suppressing melanin generation and decreasing tyrosinase activity. CONSTITUTION: A benzoic acid amide compound, an isomer thereof, pharmaceutically-acceptable salt thereof, a prodrug thereof, a hydrate thereof, or a solvate thereof is represented by chemical formula 1. In the chemical formula 1: each of R1, R3, and R4 is independently selected from hydrogen, hydroxy, C1-C5 alkoxy, C3-C6 cycloalkoxy, aryloxy, and C1-C15 haloalkoxy; R2 is selected from hydrogen, C1-C5 alkyl, C3-C6 cycloalkyl, aryl, and C1-C5 haloalkyl; and n is an integer from 1-5.
Abstract translation: 目的：提供苯甲酸酰胺化合物以通过抑制黑色素产生和降低酪氨酸酶活性而具有优异的美白效果而没有副作用。 构成：化学式1表示苯甲酸酰胺化合物，其异构体，药学上可接受的盐，其前药，其水合物或其溶剂合物。在化学式1中，R1，R3和 R 4独立地选自氢，羟基，C 1 -C 5烷氧基，C 3 -C 6环烷氧基，芳氧基和C 1 -C 15卤代烷氧基; R2选自氢，C1-C5烷基，C3-C6环烷基，芳基和C1-C5卤代烷基; n为1-5的整数。
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公开(公告)号：KR1020110138000A
公开(公告)日：2011-12-26
申请号：KR1020100058067
申请日：2010-06-18
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/48
Abstract: PURPOSE: An antithrombotic composition containing colored bean extract and fraction thereof is provided to contain adenosine and to treat cardiovascular and cerebralvascular diseases and hypertension. CONSTITUTION: An antithrombotic composition contains colored bean extract isolated using water, C1-C5 alcohol, or mixture thereof and organic acid. The organic acid includes citric acid, acetic acid, butyric acid, palmitic acid, oxalic acid, tartaric acid, carboxylic acid, or sulfonic acid. The C1-C5 alcohol is methane, ethanol, isopropylalcohol, n-propyl alcohol, n-butanol, or isobutanol. A fraction of the extract is prepared by fractioning the alcohol extract of colored beans using a synthetic adsorption column containing polystylene and benzene polymers.
Abstract translation: 目的：提供含有彩色豆提取物及其级分的抗血栓形成组合物，用于含有腺苷并治疗心血管和脑血管疾病和高血压。 构成：抗血栓组合物含有使用水，C1-C5醇或其混合物和有机酸分离的有色豆提取物。 有机酸包括柠檬酸，乙酸，丁酸，棕榈酸，草酸，酒石酸，羧酸或磺酸。 C1-C5醇是甲烷，乙醇，异丙醇，正丙醇，正丁醇或异丁醇。 通过使用含有聚苯乙烯和苯聚合物的合成吸附塔对有色豆的醇提取物进行分级来制备提取物的一部分。
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