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公开(公告)号：WO2013096425A2
公开(公告)日：2013-06-27
申请号：PCT/US2012/070572
申请日：2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： XU, Guofeng , MILLER, Steven , GRONLUND, Jennifer
CPC classification number: A61K8/362 , A61K8/0283 , A61K8/36 , A61K8/49 , A61K8/731 , A61K8/8152 , A61K8/88 , A61K2800/52 , A61Q11/00 , A61Q19/10
Abstract: Described herein are compositions comprising an unactivated liquid, an immobilized sparingly soluble acid or base, such that during storage the unactivated liquid is not in contact with the immobilized sparingly soluble acid or base, but upon use, the unactivated liquid contacts the immobilized sparingly soluble acid or base, whereby the pH of the liquid is altered, thereby activating the liquid to provide a benefit; together with variant and alternative designs, methods of making and using the compositions, and components thereof.
Abstract translation: 本文描述的是包含未活化液体，固定化的微溶酸或碱的组合物，使得在储存期间未活化液体不与固定化的微溶酸或碱接触，但是在使用时，未活化的液体与固定的微溶酸接触 或碱，由此改变液体的pH，从而激活液体以提供益处; 以及变体和替代设计，制备和使用组合物的方法及其组分。
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公开(公告)号：WO2013096321A9
公开(公告)日：2013-06-27
申请号：PCT/US2012/070371
申请日：2012-12-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： BOYD, Thomas J. , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , MILLER, Steven , VISCIO, David , FOSSER, Kari A. , DICOSIMO, Robert , WANG, Hong
Abstract: Described herein are tooth whitening strips comprising an hydratable adhesive film having a granular bleaching ingredient attached thereto, wherein upon hydration, the granular bleaching ingredient releases hydrogen peroxide which is used by an enzyme catalyst having perhydrolytic activity to enzymatically produce an effective amount of peracid bleaching agent from an acyl donor substrate. Methods of making and use the tooth whitening strips are also provided.
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53.发明申请ORAL CARE COMPOSITIONS COMPRISING N-BUTYL MAGNOLOL AND ISOBUTYL MAGNOLOL 审中-公开包含N-BUTYL MAGNOLOL和ISOBUTYL MAGNOLOL的口腔护理组合物
公开(公告)号：WO2013081627A1
公开(公告)日：2013-06-06
申请号：PCT/US2011/063031
申请日：2011-12-02
Applicant: COLGATE-PALMOLIVE COMPANY , FEI, Lin , JARACZ, Stanislav , YANG, Ying , XU, Guofeng
Inventor： FEI, Lin , JARACZ, Stanislav , YANG, Ying , XU, Guofeng
CPC classification number: A61K8/347 , A61K36/57 , A61K36/575 , A61K2800/49 , A61K2800/5922 , A61Q11/00
Abstract: Oral care compositions comprising isobutyl magnolol and n -butyl magnolol. A method of enhancing the solubility of isobutyl magnolol in an oral care composition comprises admixing n -butyl magnolol with an orally acceptable carrier comprising isobutyl magnolol. The composition may be used to treat diseases or conditions of the oral cavity such as caries, gingivitis, periodontitis, tooth yellowing and halitosis.
Abstract translation: 包含异丁基厚朴酚和正丁基木兰酚的口腔护理组合物。 提高口腔护理组合物中异丁基木兰醇的溶解度的方法包括将正丁基厚朴酚与包含异丁基木洛酚的口服可接受的载体混合。 该组合物可用于治疗口腔疾病或病症，例如龋齿，牙龈炎，牙周炎，牙齿黄变和口臭。
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公开(公告)号：WO2012105932A1
公开(公告)日：2012-08-09
申请号：PCT/US2011/023099
申请日：2011-01-31
Applicant: COLGATE-PALMOLIVE COMPANY , PILLAI, Shyamala , FEI, Lin , XU, Guofeng
Inventor： PILLAI, Shyamala , FEI, Lin , XU, Guofeng
CPC classification number: A61K47/02 , A61K8/19 , A61K8/347 , A61K8/35 , A61K8/99 , A61K31/05 , A61Q11/00 , A61Q19/08
Abstract: Described herein are compositions comprising an active compound from an extract of magnolia, or a derivative thereof; and a non-surfactant electrolyte in an amount effective to stabilize the composition, and methods of making and using the same.
Abstract translation: 本文描述的是包含来自木兰提取物的活性化合物或其衍生物的组合物; 和有效稳定组合物的量的非表面活性剂电解质及其制备和使用方法。
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55.发明申请APPARATUS FOR CONDUCTING ORAL CARE EXPERIMENTS AND METHOD OF FORMING AND USING THE SAME 审中-公开用于进行口腔护理实验的装置及其形成和使用方法
公开(公告)号：WO2012078137A1
公开(公告)日：2012-06-14
申请号：PCT/US2010/059193
申请日：2010-12-07
Applicant: COLGATE-PALMOLIVE COMPANY , PILLAI, Shyamala , XU, Guofeng
Inventor： PILLAI, Shyamala , XU, Guofeng
CPC classification number: B23Q3/18 , A61C19/00 , A61C19/04 , A61C19/10 , G09B23/283 , Y10T29/49567
Abstract: An apparatus for conducting oral care experiments with enamel block substrates (140) and a method of forming and using the same. In one aspect, the invention can be an apparatus for conducting oral care experiments comprising: a plate having a first major surface (111) and a second major surface (112); a handle (170) coupled to and extending from the plate; and at least one enamel block substrate mounted on the first major surface of the plate.
Abstract translation: 用于用搪瓷块基片进行口腔护理实验的装置（140）及其形成和使用方法。 一方面，本发明可以是用于进行口腔护理实验的装置，包括：具有第一主表面（111）和第二主表面（112）的板; 联接到所述板并从所述板延伸的手柄（170） 以及安装在所述板的第一主表面上的至少一个搪瓷块基板。
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Patent Agency Ranking
公开(公告)号：WO2009124310A1
公开(公告)日：2009-10-08
申请号：PCT/US2009/039651
申请日：2009-04-06
Applicant: COLGATE-PALMOLIVE COMPANY , HALUKO SCHAEFFER, Jennifer , XU, Guofeng , PERU, Deborah, A. , SUBRAMANYAM, Ravi
Inventor： HALUKO SCHAEFFER, Jennifer , XU, Guofeng , PERU, Deborah, A. , SUBRAMANYAM, Ravi
CPC classification number: G01N21/33 , A46B15/0002 , A46B15/0004 , A46B15/0034 , A46B2200/1066 , A61B5/0075 , A61B5/4547 , A61B5/4552 , A61B5/6887 , G01N21/359
Abstract: Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the in the monitoring of the dental health of patients or in the fast, efficient screening and/ or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct or in situ analysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/ or UV spectroscopy.
Abstract translation: 描述了用于评估试剂沉积到基底上的程度的改进的分析，诊断，监测和其它方法（及其相关的装置）。 就口服活性成分在牙齿表面上的使用而言，可以使用示例性的方法来监测患者的牙齿健康状况，或用于快速有效地筛选和/或表征制剂。 该方法涉及使用近红外光谱和/或紫外光谱直接或原位分析沉积有试剂的底物。
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公开(公告)号：WO2009073382A2
公开(公告)日：2009-06-11
申请号：PCT/US2008/084178
申请日：2008-11-20
Applicant: COLGATE-PALMOLIVE COMPANY , SUBRAMANYAM, Ravi , MATTAI, Jairajh , POTNIS, Shashank , WU, Qiang , XU, Guofeng
Inventor： SUBRAMANYAM, Ravi , MATTAI, Jairajh , POTNIS, Shashank , WU, Qiang , XU, Guofeng
CPC classification number: A61K8/922 , A61K8/375 , A61Q15/00 , A61Q19/007 , A61Q19/10 , C11C3/00 , C11C3/006 , C11C3/12 , C11D1/74 , C11D3/2082 , C11D3/2086 , C11D3/2093 , C11D3/382
Abstract: A composition of matter comprising an oil adduct synthesized by an oil and an addition material, wherein the oil includes at least one member chosen from an ethoxylated oil, a hydrogenated oil, and an ethoxylated and hydrogenated oil; wherein the average degree of ethoxylation in the ethoxylated (optionally hydrogenated) oil is less than about 10 based on moles of ethylene oxide per mole of oil; wherein the hydrogenated (optionally ethoxylated) oil has an iodine value of less than about 75; wherein the oil is capable of undergoing reaction with the addition material through a hydroxyl group of the oil; and wherein the addition material includes at least one member chosen from carboxylic acid anhydrides, maleic anhydride, dicarboxylic acids, fumaric acid, maleic acid, succinic acid, alpha hydroxy acids, beta hydroxy acids, lactic acid, glycolic acid, lactobionic acid, carnitine, salicylic acid, and (meth)acrylic acid.
Abstract translation: 包含由油和添加材料合成的油加合物的物质组合物，其中所述油包括选自乙氧基化油，氢化油和乙氧基化和氢化油中的至少一种; 其中乙氧基化（任选氢化的）油中的平均乙氧基化度基于每摩尔油的环氧乙烷摩尔数小于约10; 其中所述氢化（任选乙氧基化）油具有小于约75的碘值; 其中所述油能够通过所述油的羟基与所述添加材料发生反应; 并且其中所述添加材料包括选自羧酸酐，马来酸酐，二羧酸，富马酸，马来酸，琥珀酸，α-羟基酸，β-羟基酸，乳酸，羟基乙酸，乳糖酸，肉碱， 水杨酸和（甲基）丙烯酸。
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公开(公告)号：WO2004009050A1
公开(公告)日：2004-01-29
申请号：PCT/US2003/022530
申请日：2003-07-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： SZELES, Lori, H. , MOHSENI, Sonya , XU, Guofeng , WILLIAMS, Malcolm , VISCIO, David, B. , MASTERS, James, G.
IPC: A61K7/16
CPC classification number: A61K8/0208 , A61K8/66 , A61K8/731 , A61Q11/00
Abstract: An orally consumable film composition for delivering breath freshening agents to the oral cavity which is rapidly dissolvable or dispersible in the oral cavity, the composition being comprised of a homogeneous mixture of a water dispersible film forming polymer and an enzyme.
Abstract translation: 一种用于将口腔清新剂输送到口腔中的口腔消耗性薄膜组合物，其可快速溶解或分散在口腔中，该组合物由水分散性成膜聚合物和酶的均匀混合物组成。
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公开(公告)号：WO2003072075A1
公开(公告)日：2003-09-04
申请号：PCT/US2003/005319
申请日：2003-02-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： XU, Guofeng , VISCIO, David, B.
IPC: A61K7/16
CPC classification number: A61K8/0208 , A61K6/0023 , A61K8/19 , A61K8/22 , A61K8/86 , A61K2800/31 , A61Q11/00 , C08L71/02
Abstract: A thin, flexible film which when applied to stained teeth is hydrated by saliva and is effective in such form to whiten teeth, the film comprising an anhydrous water hydratable ethylene oxide polymer matrix containing a solid peroxide whitening agent whereby upon application to stained tooth surfaces, the peroxide whitening agent is solublilized by saliva present in the oral cavity into active whitening activity when the film is positioned and placed on the teeth.
Abstract translation: 当施用于染色的牙齿时，薄而柔韧的薄膜被唾液水合并且以这种形式有效地使牙齿变白，所述薄膜包含含有固体过氧化物增白剂的无水可水合的环氧乙烷聚合物基质 由此当施用于染色的牙齿表面时，当将薄膜定位并放置在牙齿上时，过氧化物增白剂通过存在于口腔中的唾液溶解成活性增白活性。
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公开(公告)号：WO2022140280A1
公开(公告)日：2022-06-30
申请号：PCT/US2021/064401
申请日：2021-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： MYERS, Carl , XU, Guofeng , ZHANG, Shaoyi , TANG, Saide
Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride, and/or stannous chloride, and/or stannous pyrophosphate and potassium salts, with a polyphosphate source, wherein the polyphosphate source comprises three or more phosphate moieties or units, in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, relief from dental hypersensitivity, and to treat or reduce malodor.
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