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    ORAL CARE COMPOSITIONS AND METHODS
    1.
    发明申请
    ORAL CARE COMPOSITIONS AND METHODS 审中-公开

    公开(公告)号：WO2022140280A1

    公开(公告)日：2022-06-30

    申请号：PCT/US2021/064401

    申请日：2021-12-20

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： MYERS, Carl ,  XU, Guofeng ,  ZHANG, Shaoyi ,  TANG, Saide

    IPC: A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/55 ,  A61Q11/00

    Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride, and/or stannous chloride, and/or stannous pyrophosphate and potassium salts, with a polyphosphate source, wherein the polyphosphate source comprises three or more phosphate moieties or units, in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, relief from dental hypersensitivity, and to treat or reduce malodor.

    CORE-SHELL SILICA AND METHOD FOR PRODUCING SAME
    3.
    发明申请
    CORE-SHELL SILICA AND METHOD FOR PRODUCING SAME 审中-公开

    公开(公告)号：WO2019035839A1

    公开(公告)日：2019-02-21

    申请号：PCT/US2017/047494

    申请日：2017-08-18

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： TANG, Saide ,  FEI, Lin ,  CHOPRA, Suman

    IPC: A61K8/25 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/02 ,  A61K8/19

    Abstract: Methods for preparing high loading core shell silica (CSS) particles, or CSS particles having a relatively greater amount of surface active silicate groups than CSS particles prepared according to conventional methods is provided. The method may include contacting silica particles with a base having a first metal ion to produce core shell silica particles. Each of the core shell silica particles may include a silica core and a silicate of the first metal ion etched on a surface of the silica core. The method may also include contacting each of the core shell silica particles having the silicate of the first metal ion with an acidic aqueous solution including a metal salt having a second metal ion to produce core shell silica particles including the silica core and a silicate of the second metal ion on the surface of the silica core.

    ORAL CARE COMPOSITIONS
    4.
    发明申请
    ORAL CARE COMPOSITIONS 审中-公开

    公开(公告)号：WO2022251439A1

    公开(公告)日：2022-12-01

    申请号：PCT/US2022/031052

    申请日：2022-05-26

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： NAKAJIMA, Murilo, Nogueira ,  TANG, Saide ,  UTIMA, Enzo ,  XU, Guofeng ,  PIMENTA, Paloma

    IPC: A61K8/41 ,  A61K8/43 ,  A61K8/44 ,  A61K8/49 ,  A61K8/73 ,  A61Q11/00

    Abstract: This application provides, among other things, oral care compositions where the addition of a stabilizing amount of a nonionic gelling and thickening agent, (e.g., hydroxyethyl cellulose (HEC)) and an effective amount of a zwitterionic surfactant (e.g., a betaine zwitterionic surfactant) (e.g., cocamidopropyl betaine), to formulations comprising a bisbiguanide (e.g., chlorhexidine (CHX)) agent, and optionally an effective amount of abrasive silica, allows for proper structure and consistency to the formulation and to allow it to be used as a gel or a toothpaste to facility delivery of chlorhexidine, among other actives, to the teeth or gums with acceptable stability and foaming.

    ORAL CARE COMPOSITIONS
    7.
    发明申请
    ORAL CARE COMPOSITIONS 审中-公开

    公开(公告)号：WO2020132375A1

    公开(公告)日：2020-06-25

    申请号：PCT/US2019/067689

    申请日：2019-12-19

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： TANG, Saide ,  FEI, Lin ,  CHOPRA, Suman ,  UTGIKAR, Neelima

    IPC: A61K8/02 ,  A61K8/19 ,  A61K8/25 ,  A61K8/27 ,  A61Q11/00

    Abstract: Described herein are oral care compositions comprising an orally acceptable carrier; an abrasive system comprising a calcium-based abrasive; and a core shell silica particle comprising; a metal silicate; and a silica particle comprising a core having a surface; wherein the metal silicate is chemically bound to a surface of the silica core; and wherein the metal silicate comprises a silicate of a divalent metal ion. Methods of making and using these compositions are also described.

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