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公开(公告)号：WO2013096321A9
公开(公告)日：2013-06-27
申请号：PCT/US2012/070371
申请日：2012-12-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： BOYD, Thomas J. , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , MILLER, Steven , VISCIO, David , FOSSER, Kari A. , DICOSIMO, Robert , WANG, Hong
Abstract: Described herein are tooth whitening strips comprising an hydratable adhesive film having a granular bleaching ingredient attached thereto, wherein upon hydration, the granular bleaching ingredient releases hydrogen peroxide which is used by an enzyme catalyst having perhydrolytic activity to enzymatically produce an effective amount of peracid bleaching agent from an acyl donor substrate. Methods of making and use the tooth whitening strips are also provided.
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2.发明申请DENTAL-BLEACHING COMPOSITIONS AND METHODS WITH REDUCED PEROXIDE CONCENTRATION 审中-公开牙齿漂白组合物和减少过氧化物浓度的方法
公开(公告)号：WO2005072692A1
公开(公告)日：2005-08-11
申请号：PCT/US2005/002332
申请日：2005-01-25
Applicant: COLGATE-PALMOLIVE COMPANY , ZAIDEL, Lynette, Anne , LIN, Nora, Chila , VISCIO, David
Inventor： ZAIDEL, Lynette, Anne , LIN, Nora, Chila , VISCIO, David
IPC: A61K7/16
Abstract: A peroxide containing dual component dentifrice composition providing enhanced whitening efficacy and minimal gingival irritation and tooth sensitivity, the composition being comprised of a separately maintained first aqueous dentifrice component containing a peroxide compound and an abrasive system compatible with the peroxide and a second aqueous dentifrice component containing a desensitizing compound and an abrasive that is incompatible with peroxide compound whereby when the components are mixed and combined for the first time and exposed to the surface of teeth, an enhanced whitening effect is obtained with minimal tooth sensitivity and gum irritation.
Abstract translation: 含有双组分洁齿剂组合物的过氧化物，其提供增强的美白功效和最小的牙龈刺激和牙齿敏感性，所述组合物由含有过氧化物化合物的单独保持的第一含水洁牙组分和与过氧化物相容的研磨系统和含有 脱敏化合物和与过氧化物不相容的研磨剂，由此当第一次将组分混合并组合并暴露于牙齿表面时，获得增强的美白效果，具有最小的牙齿敏感性和牙龈刺激性。
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公开(公告)号：WO2013039495A1
公开(公告)日：2013-03-21
申请号：PCT/US2011/051546
申请日：2011-09-14
Applicant: COLGATE-PALMOLIVE COMPANY , BOYD, Thomas , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , MILLER, Steven , VISCIO, David
Inventor： BOYD, Thomas , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , MILLER, Steven , VISCIO, David
CPC classification number: A61K8/0245 , A61K8/0208 , A61K8/22 , A61K8/38 , A61K8/731 , A61K8/8141 , A61K8/8147 , A61K2800/56 , A61K2800/87 , A61Q11/00
Abstract: Described herein are tooth whitening strips comprising a hydratable adhesive film with a first side and a second side, the first side having a granular bleaching ingredient attached thereto in an amount effective to whiten teeth, together with methods of making and using the same.
Abstract translation: 本文描述的是牙齿美白条，其包括具有第一侧和第二侧的可水合的粘合剂膜，第一侧具有以有效增白牙齿的量连接到其上的颗粒漂白成分，以及制备和使用它们的方法。
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公开(公告)号：WO2006069210A3
公开(公告)日：2006-06-29
申请号：PCT/US2005/046522
申请日：2005-12-21
Applicant: COLGATE-PALMOLIVE COMPANY , XU, Guofeng , BOYD, Thomas, J. , HAO, Zhigang , VISCIO, David , GAFFAR, Abdul , MELLO, Sarita, V. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
Inventor： XU, Guofeng , BOYD, Thomas, J. , HAO, Zhigang , VISCIO, David , GAFFAR, Abdul , MELLO, Sarita, V. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
IPC: A61Q11/02 , A61Q11/00 , A61K8/19 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/49 , A61K8/81 , A61P29/00
Abstract: Oral care compositions containing: a free-B-ring flavonoid and a flavan; as well as at least one bioavailability-enhancing agent are provided. Methods of using the oral compositions are also provided.
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公开(公告)号：WO2013095331A1
公开(公告)日：2013-06-27
申请号：PCT/US2011/065827
申请日：2011-12-19
Applicant: COLGATE-PALMOLIVE COMPANY , BOYD, Thomas , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , SAMAROO, Derek , VISCIO, David
Inventor： BOYD, Thomas , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , SAMAROO, Derek , VISCIO, David
CPC classification number: A61K8/66 , A61K8/35 , A61K8/37 , A61K8/38 , A61K8/42 , A61K2800/74 , A61K2800/882 , A61Q11/00 , B65D35/22
Abstract: Described herein are packages for storing and dispensing multi-part tooth whitening formulations, wherein the contents of the parts are mixed, a peracid and/or dioxirane whitening agent is formed. Particular multi-part tooth whitening formulations using this principle and methods of use thereof are also provided.
Abstract translation: 本文描述的是用于储存和分配多部分牙齿美白配方的包装，其中将部件的内容物混合，形成过酸和/或二环氧乙烷增白剂。 还提供了使用该原理的特定的多部分牙齿美白配方及其使用方法。
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Patent Agency Ranking
公开(公告)号：WO2006071712A1
公开(公告)日：2006-07-06
申请号：PCT/US2005/046514
申请日：2005-12-21
Applicant: COLGATE-PALMOLIVE COMPANY , BOYD, Thomas , GAFFAR, Abdul , VISCIO, David
Inventor： BOYD, Thomas , GAFFAR, Abdul , VISCIO, David
CPC classification number: A61K8/8164 , A61K8/97 , A61K36/82 , A61Q11/00 , A61K2300/00
Abstract: Oral composition comprising a Camellia extract of semi-oxidized tissue from a member of the genus Camellia and an enhancing agent.
Abstract translation: 包含来自山茶属的半氧化组织的山茶提取物和增强剂的口腔组合物。
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公开(公告)号：WO2013096318A3
公开(公告)日：2013-06-27
申请号：PCT/US2012/070367
申请日：2012-12-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： BOYD, Thomas J. , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , SAMAROO, Derek , VISCIO, David , FOSSER, Kari A. , DICOSIMO, Robert , WANG, Hong
Abstract: Described herein are packages for storing and dispensing multi-part tooth whitening formulations, comprising a deformable material configured to form two or more sealed chambers, e.g., wherein the first chamber contains a low viscosity liquid solution comprising an enzyme having perhydrolytic activity, and the second chamber contains a peroxide source and a at least one acyl donor substrate. Particular multi-part tooth whitening formulations using this principle and methods of use thereof are also provided.
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公开(公告)号：WO2007013937A1
公开(公告)日：2007-02-01
申请号：PCT/US2006/028090
申请日：2006-07-20
Applicant: COLGATE-PALMOLIVE COMPANY , BOYD, Thomas, J. , XU, Guofeng , VISCIO, David , GAFFAR, Abdul , ARVANITIDOU, Evangelia , FRUGE, Linh
Inventor： BOYD, Thomas, J. , XU, Guofeng , VISCIO, David , GAFFAR, Abdul , ARVANITIDOU, Evangelia , FRUGE, Linh
CPC classification number: A61Q11/00 , A61K8/27 , A61K2800/413 , B82Y5/00
Abstract: An oral composition comprising a vehicle and a zinc ion source in the form of nanoparticles that are substantially non-aggregated and methods for use of such compositions are described. The composition provides antiplaque and anti malodor benefits to the user and the inclusion of nanoparticles permits a reduction in the amount of zinc ions present in the composition while maintaining efficacy.
Abstract translation: 描述了包含基本上不聚集的纳米颗粒形式的载体和锌离子源的口腔组合物以及使用这种组合物的方法。 组合物为使用者提供抗斑和抗恶臭益处，并且包含纳米颗粒允许在保持功效的同时减少组合物中存在的锌离子的量。
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公开(公告)号：WO2005110344A1
公开(公告)日：2005-11-24
申请号：PCT/US2005/016165
申请日：2005-05-10
Applicant: COLGATE-PALMOLIVE COMPANY , HASSAN, Mahmoud , XU, Guofeng , VISCIO, David , GAFFAR, Abdul
Inventor： HASSAN, Mahmoud , XU, Guofeng , VISCIO, David , GAFFAR, Abdul
IPC: A61K7/16
CPC classification number: A61K8/0208 , A61C19/066 , A61K8/22 , A61K8/731 , A61K8/8176 , A61K8/86 , A61Q11/00
Abstract: Tooth-whitening films comprising a hydratable polymer and a whitening agent are disclosed in which the films have a hydrophobic coating on one surface and a tooth-adherent coating on the opposing surface. Flavorings can also be included in the hydratable polymer portion of the film or in either the hydrophobic coating or the tooth-adherent coating. Tooth-whitening methods that use the films are also disclosed. The hydratable polymer preferably is a polyethylene oxide.
Abstract translation: 公开了包含可水合聚合物和增白剂的牙齿增白膜，其中所述膜在一个表面上具有疏水性涂层，并且在相对表面上具有牙齿粘附涂层。 调味剂也可以包括在膜的可水合的聚合物部分中或在疏水性涂层或牙粘附涂层中。 还公开了使用这些膜的牙齿美白方法。 可水合的聚合物优选为聚环氧乙烷。
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公开(公告)号：EP2793822B1
公开(公告)日：2016-08-24
申请号：EP12806321.1
申请日：2012-12-18
Inventor： BOYD, Thomas J. , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , MILLER, Steven , VISCIO, David , FOSSER, Kari A. , DICOSIMO, Robert , WANG, Hong
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