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公开(公告)号：WO2020214311A1
公开(公告)日：2020-10-22
申请号：PCT/US2020/023068
申请日：2020-03-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： HAO, Zhigang , THOMSON, Paul , PAN, Long , BRINZARI, Tatiana , XU, Guofeng , LEITE, Sergio , WANG, Yu
Abstract: Disclosed herein are improved methods for the synthesis of stannous pyrophosphate, as well as improved methods for the manufacture of oral care compositions comprising stannous pyrophosphate.
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公开(公告)号：WO2018118507A1
公开(公告)日：2018-06-28
申请号：PCT/US2017/065722
申请日：2017-12-12
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： GRONLUND, Jennifer , XU, Guofeng , MALONEY, Venda Porter , MAO, Junhong , YUAN, Shaotang , CHOPRA, Suman , PARKER, Jodie , KOHLI, Rajnish , DICOSIMO, Robert , FOSSER, Kari A , HAYNIE, Sharon , PAYNE, Mark S. , GANNON, John Thomas
Abstract: An oral care composition including an orally acceptable vehicle is disclosed. The orally acceptable vehicle includes a source of hydrogen peroxide, an acyl donor, and an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.
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公开(公告)号：WO2018118506A1
公开(公告)日：2018-06-28
申请号：PCT/US2017/065712
申请日：2017-12-12
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： YUAN, Shaotang , XU, Guofeng , DICOSIMO, Robert , HAYNIE, Sharon
Abstract: An oral care composition, including a peroxydone complex, a dispersant, and a polyvinylpyrrolidone copolymer structure-building agent.
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公开(公告)号：WO2016106075A1
公开(公告)日：2016-06-30
申请号：PCT/US2015/066331
申请日：2015-12-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： JOHANSSON, Patrik , XU, Guofeng
IPC: A61Q11/00 , A46B15/00 , A61N1/44 , A61C19/06 , A61K8/23 , A61L2/03 , A61L2/18 , A61N1/05 , A61N1/26 , A61N1/32
CPC classification number: A61K8/23 , A46B15/0022 , A61C19/066 , A61N1/0548 , A61N1/44 , A61Q11/00 , C25B1/285 , C25B9/06
Abstract: Provided is an oral care product comprising an effective amount of a soluble orally acceptable sulfate, e.g., sodium or potassium bisulfate, in a buffered, electrically conductive medium, which product is useful in a method for in situ production of persulfate (S 2 O 8 2- ), and methods of making and using the same, for example for whitening the teeth.
Abstract translation: 本发明提供的口腔护理产品包含有效量的可溶性口服可接受的硫酸盐，例如硫酸氢钠或硫酸氢钾，在缓冲的导电介质中，该产品可用于原位生产过硫酸盐的方法（S2O8 2-） ，以及制造和使用它们的方法，例如使牙齿美白。
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公开(公告)号：WO2014098829A1
公开(公告)日：2014-06-26
申请号：PCT/US2012/070537
申请日：2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： XU, Guofeng , LIU, Zhiqiang , PAN, Long , KILPATRICK-LIVERMAN, LaTonya , YANG, Ying , STRANICK, Michael A. , HAO, Zhigang
CPC classification number: A61K8/27 , A61K8/20 , A61K8/21 , A61K8/44 , A61K2800/58 , A61K2800/92 , A61Q11/00
Abstract: Described herein are oral care compositions comprising a mixture of zinc oxide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
Abstract translation: 本文描述了包含游离或口服可接受的盐形式的氧化锌和三甲基甘氨酸的混合物的口腔护理组合物。 还提供了制备和使用组合物的方法。
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Patent Agency Ranking6.发明申请ORAL CARE PRODUCTS COMPRISING TETRABASIC ZINC CHLORIDE AND TRIMETHYLGLYCINE 审中-公开包含四氯化钛和三甲基氯化铵的口腔护理产品
公开(公告)号：WO2014098827A1
公开(公告)日：2014-06-26
申请号：PCT/US2012/070528
申请日：2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： KILPATRICK-LIVERMAN, LaTonya , LIU, Zhiqiang , PAN, Long , YANG, Ying , XU, Guofeng , STRANICK, Michael A. , HAO, Zhigang
CPC classification number: A61K8/27 , A61K8/21 , A61K8/416 , A61K8/44 , A61K2800/74 , A61Q11/00 , C07C229/12
Abstract: The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
Abstract translation: 本发明提供包含游离或口服可接受的盐形式的四元卤化锌和三甲基甘氨酸的混合物的口腔护理组合物。 还提供了制备和使用组合物的方法。
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公开(公告)号：WO2014098817A1
公开(公告)日：2014-06-26
申请号：PCT/US2012/070497
申请日：2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： HAO, Zhigang , YANG, Ying , LIU, Zhiqiang , XU, Guofeng , VINCENTI, Paul Joseph
CPC classification number: A61K8/58 , A61K8/27 , A61K8/55 , A61K8/676 , A61K33/30 , A61K2800/58 , A61Q11/00
Abstract: Provided herein is an oral care composition comprising an orally-acceptable aqueous vehicle and an antimicrobial ingredient, wherein the antimicrobial ingredient comprises a zinc ascorbylphosphate and methods for treating or preventing a disease or disorder of the oral cavity using the oral care compositions disclosed herein.
Abstract translation: 本文提供了包含口服可接受的水性载体和抗微生物成分的口腔护理组合物，其中所述抗微生物成分包含抗坏血酸磷酸锌和使用本文公开的口腔护理组合物治疗或预防口腔疾病或病症的方法。
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公开(公告)号：WO2013096182A2
公开(公告)日：2013-06-27
申请号：PCT/US2012/070062
申请日：2012-12-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： JARACZ, Stanislav , XU, Guofeng , MILLER, Steven , LEIGH, Leonora , PICQUET, Guillaume , DU-THUMM, Laurence
IPC: A61K8/37 , A61K31/235 , A61K31/166 , C07C69/88 , C07C235/54 , A61K8/42 , A61Q11/00 , A61P31/04 , A61P17/10 , A61P17/02 , A61P29/00 , A61K8/67 , A61K8/66
CPC classification number: A61Q11/00 , A61K8/37 , A61K8/375 , A61K8/42 , A61K31/166 , A61K31/235 , A61Q17/005 , C07C69/84 , C07C235/54 , C07C2601/14 , C07C2602/08
Abstract: Described herein are compositions for topical use comprising an antibacterially effective concentration of a gallate or gallamide compound which is a polysubstituted cycloalkyl or heterocycloalkyl wherein the substituents are selected from hydroxy, hydroxymethyl, fluoro, chloro, amino, nitro, or a moiety of formula -X-(CO)-(3,4,5-trihydroxyphenyl), wherein X is selected from O and NH, provided that the substituents comprise at least two moieties of formula -X-(CO)-(3,4,5-trihydroxyphenyl) attached to adjacent carbons in free or in orally or topically acceptable salt form, as well as methods of making and using the same.
Abstract translation: 本文描述的是用于局部使用的组合物，其包含抗菌有效浓度的没食子酸酯或胆酰胺化合物，其为多取代的环烷基或杂环烷基，其中取代基选自羟基，羟甲基，氟，氯，氨基，硝基或式-X - （CO） - （3,4,5-三羟基苯基），其中X选自O和NH，条件是取代基包含至少两个式-X-（CO） - （3,4,5-三羟基苯基 ）以游离或口服或局部可接受的盐形式附着在相邻的碳上，以及制备和使用它们的方法。
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公开(公告)号：WO2013039495A1
公开(公告)日：2013-03-21
申请号：PCT/US2011/051546
申请日：2011-09-14
Applicant: COLGATE-PALMOLIVE COMPANY , BOYD, Thomas , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , MILLER, Steven , VISCIO, David
Inventor： BOYD, Thomas , XU, Guofeng , ADAMS, Richard , PIERCE, Robert , MILLER, Steven , VISCIO, David
CPC classification number: A61K8/0245 , A61K8/0208 , A61K8/22 , A61K8/38 , A61K8/731 , A61K8/8141 , A61K8/8147 , A61K2800/56 , A61K2800/87 , A61Q11/00
Abstract: Described herein are tooth whitening strips comprising a hydratable adhesive film with a first side and a second side, the first side having a granular bleaching ingredient attached thereto in an amount effective to whiten teeth, together with methods of making and using the same.
Abstract translation: 本文描述的是牙齿美白条，其包括具有第一侧和第二侧的可水合的粘合剂膜，第一侧具有以有效增白牙齿的量连接到其上的颗粒漂白成分，以及制备和使用它们的方法。
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公开(公告)号：WO2010141694A2
公开(公告)日：2010-12-09
申请号：PCT/US2010/037223
申请日：2010-06-03
Applicant: COLGATE-PALMOLIVE COMPANY , PORTER, Venda , MORGAN, Andre , JARACZ, Stanislav , GRONLUND, Jennifer , XU, Guofeng , WU, Donghui , PRENCIPE, Michael , SUBRAMANYAM, Ravi
Inventor： PORTER, Venda , MORGAN, Andre , JARACZ, Stanislav , GRONLUND, Jennifer , XU, Guofeng , WU, Donghui , PRENCIPE, Michael , SUBRAMANYAM, Ravi
IPC: A61Q11/00
CPC classification number: A61Q11/00 , A61K8/58 , A61K31/69 , A61Q17/005 , Y10S514/835
Abstract: A stabilized topical composition comprising a borinic acid derivative, e.g., a borinic ester.
Abstract translation: 包含硼酸衍生物例如硼酸酯的稳定的局部组合物。
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