-
公开(公告)号：AU2014294866A1
公开(公告)日：2016-02-04
申请号：AU2014294866
申请日：2014-07-22
Applicant: VERNALIS R&D LTD , SERVIER LAB
Inventor： CASARA PATRICK , LE DIGUARHER THIERRY , HENLIN JEAN-MICHEL , STARCK JEROME-BENOIT , LE TIRAN ARNAUD , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , WALMSLEY CLAIRE , GRAHAM CHRISTOPHER JOHN , RAY STUART , MADDOX DANIEL , BEDFORD SIMON
IPC: C07D401/14 , A61K31/4709 , A61P35/00 , A61P37/00 , C07D401/10 , C07D405/14 , C07D471/04
Abstract: The invention relates to compounds of formula (I), wherein R
-
公开(公告)号：CL2014001853A1
公开(公告)日：2015-06-26
申请号：CL2014001853
申请日：2014-07-14
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , FEJES IMRE , TATAI JANOS , NYERGES MIKLOS , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , DURAND DIDIER
IPC: A61K31/4709 , A61P35/00 , A61P37/00 , C07D401/14 , C07D405/14 , C07D471/04 , C07D491/10 , C07D498/04
-
公开(公告)号：UY35626A
公开(公告)日：2015-02-27
申请号：UY35626
申请日：2014-06-24
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： TIRAN ARNAUD LE , CHEN I-JEN , MURRAY JAMES BROOKE , DAVIDSON JAMES EDWARD PAUL , STARCK JEROME-BENOIT , OLIVIER GENESTE , DIGUARHER THIERRY LE , NANTEUIL GUILLAUME DE , HENLIN JEAN-MICHEL
IPC: A61P35/00 , A61K31/437 , C07D209/00 , C07D221/04 , C07D271/00 , C07D471/04
Abstract: Compuestos de fórmula (I) : en la que Ra, Rb, Rc, Rd, T, R3, R4, R5, X, Y y Het son tales como se han definido en la descripción.
-
公开(公告)号：CA2917965A1
公开(公告)日：2015-01-29
申请号：CA2917965
申请日：2014-07-22
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： CASARA PATRICK , LE DIGUARHER THIERRY , HENLIN JEAN-MICHEL , STARCK JEROME-BENOIT , LE TIRAN ARNAUD , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , WALMSLEY CLAIRE , GRAHAM CHRISTOPHER JOHN , RAY STUART , MADDOX DANIEL , BEDFORD SIMON
IPC: C07D401/14 , A61K31/4709 , A61P35/00 , A61P37/00 , C07D401/10 , C07D405/14 , C07D471/04
Abstract: Composés de formule (I) dans laquelle Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2,T et W sont tels que définis dans la description. Médicaments.
-
公开(公告)号：MD20140084A2
公开(公告)日：2014-12-31
申请号：MD20140084
申请日：2013-01-23
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE DIGUARHER THIERRY , CASARA PATRICK , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , GRAHAM CHRISTOPHER JOHN , CHEN I-JEN , GENESTE OLIVIER , HICKMAN JOHN , DEPIL STEPHANE , LE TIRAN ARNAUD , NYERGES MIKLOS , DE NANTEUIL GUILLAUME
IPC: A61K31/407 , C07D471/00 , A61K31/4353 , A61K31/436 , A61P35/00 , A61P37/00 , C07D471/04 , C07D487/04 , C07D491/052
Abstract: Se revendică următoarele:compuşi cu formula (I):unde Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5,, X, Y şi Het sunt definiţi în descriere;procedeu de obţinere a compuşilor cu formula (I); compoziţii farmaceutice care conţin un compus cu formula (I) sau o sare de adiţie a acestuia cu un acid sau o bază acceptabilă farmaceutic; şi utilizarea compoziţiilor farmaceutice în fabricarea medicamentelor.
-
Patent Agency Ranking56.发明专利
公开(公告)号：AU2013213474A1
公开(公告)日：2014-07-24
申请号：AU2013213474
申请日：2013-01-23
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE DIGUARHER THIERRY , CASARA PATRICK , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , GRAHAM CHRISTOPHER JOHN , CHEN I-JEN , GENESTE OLIVIER , HICKMAN JOHN , DEPIL STEPHANE , LE TIRAN ARNAUD , NYERGES MIKLOS , DE NANTEUIL GUILLAUME
IPC: C07D471/00 , A61K31/407 , A61K31/4353 , A61K31/436 , A61P35/00 , A61P37/00 , C07D471/04 , C07D487/04 , C07D491/052
Abstract: Compounds of formula (I) wherein R
-
57.发明专利
公开(公告)号：CA2861160A1
公开(公告)日：2013-08-01
申请号：CA2861160
申请日：2013-01-23
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE DIGUARHER THIERRY , CASARA PATRICK , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , GRAHAM CHRISTOPHER JOHN , CHEN I-JEN , GENESTE OLIVIER , HICKMAN JOHN , DEPIL STEPHANE , LE TIRAN ARNAUD , NYERGES MIKLOS , DE NANTEUIL GUILLAUME
IPC: C07D471/00 , A61K31/407 , A61K31/4353 , A61K31/436 , A61P35/00 , A61P37/00 , C07D471/04 , C07D487/04 , C07D491/052
Abstract: Compounds of formula (I) wherein Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5; X, Y and Het are as defined in the description.
-
公开(公告)号：SI4003989T1
公开(公告)日：2024-04-30
申请号：SI202030373
申请日：2020-07-28
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： NOVAK TIBOR , DAVIDSON JAMES EDWARD PAUL , PACZAL ATTILA , STARCK JEROME-BENOIT , KOTSCHY ANDRAS , MURRAY JAMES BROOKE , BEDFORD SIMON , CHANRION MAIA , COLLAND FREDERIC , DODSWORTH MARK PHILIP , HERNER ANDRAS , MARAGNO ANA LETICIA , SANDERS EMMA , TIMARI MATYAS PAL , WEBB PAUL
IPC: C07D417/00 , A61K31/00 , A61P35/00 , A61P37/00 , C07D471/00 , C07D487/00
-
公开(公告)号：GEP20237581B
公开(公告)日：2023-12-25
申请号：GEAP2020015865
申请日：2020-07-28
Applicant: VERNALIS R&D LTD , SERVIER LAB
Inventor： NOVÁK TIBOR , DAVIDSON JAMES EDWARD PAUL , PACZAL ATTILA , STARCK JEROME-BENOIT , KOTSCHY ANDRÁS , MURRAY JAMES BROOKE , BEDFORD SIMON , CHANRION MAÏA , COLLAND FRÉDÉRIC , DODSWORTH MARK PHILIP , HERNER ANDRÁS , MARAGNO ANA LETICIA , SANDERS EMMA , TIMÁRI MÁTYÁS PÁL , WEBB PAUL
IPC: C07D417/14 , A61K31/404 , A61K31/4155 , A61K31/427 , A61K31/428 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/5025 , A61K31/538 , A61K31/55 , A61P35/00 , A61P37/00 , A61P37/02 , C07D471/04 , C07D487/04
Abstract: Present invention relates to 6,7-dihydro-5H-pyrido[2,3- c]pyridazine, 1,2,3,4-tetrahydroquinoline, 1H-indole, 3,4- dihydro-2H-1,4-benzoxazine, 1H-pyrrolo[2,3-b]pyridin-1-yl, 7H- pyrrolo[2,3-c]pyridazine, 5H,6H,7H,8H,9H-pyridazino[3,4-b]azepine derivatives of formula (IA), (IA) pharmaceutical compositions containing them, and their usage as pro-apoptotic agents for the treatment of cancer, and immune and autoimmune diseases. s
-
60.发明专利
公开(公告)号：MY172811A
公开(公告)日：2019-12-12
申请号：MYPI2014701842
申请日：2013-01-23
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： LE DIGUARHER THIERRY , CASARA PATRICK , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , GRAHAM CHRISTOPHER JOHN , CHEN I-JEN , GENESTE OLIVIER , HICKMAN JOHN , DEPIL STEPHANE , ARNAUD LE TIRAN , NYERGES MIKLOS , DE NANTEUIL GUILLAUME
Abstract: Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
-
-
-
-
-
-
-
-
-
Search Results
101
records
(took 0.03 seconds)
