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    PURIFICATION OF ION EXCHANGER
    51.
    发明专利
    PURIFICATION OF ION EXCHANGER 失效

    公开(公告)号：JPS60102949A

    公开(公告)日：1985-06-07

    申请号：JP21090783

    申请日：1983-11-11

    Applicant: TORAY INDUSTRIES

    Inventor： HENMI MASAHIRO ,  YOSHIOKA TOSHIO ,  SHIMAMURA SEIJI

    IPC: B01J47/12 ,  B01J47/00 ,  C08J5/20

    Abstract: PURPOSE:To obtain an ion exchanger containing extremely little impurities and having excellent whiteness, by treating an ion exchanger with active chlorine. CONSTITUTION:An ion exchanger, particularly, ion exchange fibers are treated with active chlorine, particularly, active chlorine generated from a chlorine base bleaching agent. The active chlorine containing compound displays its effect at a concentration of about 0.01-2mol/l. Preferably, a concentration range of 0.02- 1mol/l, more preferably, 0.05-0.5mol/l is selected in view of adverse effects of reduction in the strength of the fibers or residual chlorine. The treatment is carried out at a relatively low temperature of ordinarily not higher than 100 deg.C and not lower than 0 deg.C, preferably, not higher than 90 deg.C, more preferably, not higher than 80 deg.C. Active chlorine decolorizes the ion exchanger and remove only impurities from the ion exchanger without producing any adverse effect on ion exchange groups and water content (degree of crosslinking) which are important requisites for the ion exchanger.

    ADSORBING MATERIAL MADE OF FIBER
    54.
    发明专利
    ADSORBING MATERIAL MADE OF FIBER 失效

    公开(公告)号：JPS58122039A

    公开(公告)日：1983-07-20

    申请号：JP483182

    申请日：1982-01-18

    Applicant: TORAY INDUSTRIES

    Inventor： YOSHIOKA TOSHIO ,  SHIMAMURA SEIJI

    IPC: B01J20/28 ,  B01J47/12 ,  C12N11/08

    Abstract: PURPOSE:To obtain excellent ion exchange fibers free from clogging by using an assemblage of continuous filament lines having ion exchange groups as a fiber adsorbing material and melt-sticking both ends thereof. CONSTITUTION:A fiber assemblage of continuous filament lines having ion exchange groups which is of a columnar or cylindrical shape of about 3-30mm. length wherein fibers are melt-stuck in both end parts is used as an adsorbing material made of fiber for exchanging of low molecular ions, adsorbing and desorbing of middle and high polymer materials, etc. If the ion exchange fibers of such specific shapes are used for the adsorbing material, clogging and pressure drop are eliminated without losing the advantages of the ion exchange fibers having high surface areas and high ion adsorbing power, etc.

    CARRIER FOR IMMOBILIZING PHYSIOLOGICALLY ACTIVE SUBSTANCE AND ITS IMMOBILIZATION
    55.
    发明专利
    CARRIER FOR IMMOBILIZING PHYSIOLOGICALLY ACTIVE SUBSTANCE AND ITS IMMOBILIZATION 失效

    公开(公告)号：JPS5831990A

    公开(公告)日：1983-02-24

    申请号：JP13011881

    申请日：1981-08-21

    Applicant: TORAY INDUSTRIES

    Inventor： YOSHIOKA TOSHIO ,  SHIMAMURA SEIJI

    IPC: C12P19/24 ,  C12N11/08

    Abstract: PURPOSE:The titled carrier having a large amount of immobilization of various kinds of physiologically active substance, capable of keeping the activity stably as it is, having improved mechanical strength and microorganism pollution resistance, comprising a specific adduct of an inert polymonovinyl aromatic compound with anion exchange groups. CONSTITUTION:A carrier for immobilizing a physiologically active substance (e.g., enzyme, such as glucose isomerase, etc.) consisting of (C) an adduct of an inert polymonovinyl aromatic compound with anion exchange groups obtained by adding (A) an anion exchange group[e.g., -(NH(CH2)nNH2(n=2-12), etc.]containing a primary amino group and (B) an anion exchange group (e.g., beta-aminopropionamidomethyl group, etc.) comprising a secondary or more amino group to an inert polymonovinyl aromatic compound[e.g., (co)polymer of styrene, vinylnaphthalene, etc.].

    ADSORBENT AND COLUMN FOR EXTRACORPOREAL CIRCULATION
    59.
    发明专利
    ADSORBENT AND COLUMN FOR EXTRACORPOREAL CIRCULATION 失效

    公开(公告)号：JP2001347161A

    公开(公告)日：2001-12-18

    申请号：JP2000169009

    申请日：2000-06-06

    Applicant: TORAY INDUSTRIES

    Inventor： YOSHIOKA TOSHIO ,  TERAMOTO KAZUO ,  KOYAMA YOSHIHIRO

    IPC: A61M1/36 ,  B01J20/26

    Abstract: PROBLEM TO BE SOLVED: To provide an adsorbent which selectively adsorbs toxins, such as endotoxins, derived from bacteria in blood and inflammatory white blood cells with high efficiency and a column for extracorporeal circulation which efficiently treats inflammatory diseases. SOLUTION: This adsorbent consists of fibers having amino groups on at least the surfaces and having a diameter of

    T-CELL SELECTOR
    60.
    发明专利
    T-CELL SELECTOR 失效

    公开(公告)号：JP2001327279A

    公开(公告)日：2001-11-27

    申请号：JP2000151329

    申请日：2000-05-23

    Applicant: TORAY INDUSTRIES

    Inventor： TERAMOTO KAZUO ,  YOSHIOKA TOSHIO ,  KAWABE TAKAHIRO

    IPC: C12M1/00 ,  C12N5/07 ,  C12N5/0783 ,  C12N5/0786 ,  C12N5/09 ,  C12N11/08 ,  C12Q1/02 ,  C12N5/06

    Abstract: PROBLEM TO BE SOLVED: To provide a T-cell selector intended to select such cytotoxic T-cells with high tumor antigen specificity as to be used in cancer therapy. SOLUTION: This T-cell selector is made up of a 1st chamber packed with a base material coated with principal tissue-compatible antigen-expressing cells and a 2nd chamber packed with another base material coated with antigen- presenting cells. Using this selector, cytotoxic T-cells with high tumor antigen specificity can be selected.

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