公开(公告)号：KR100891487B1

公开(公告)日：2009-04-01

申请号：KR1020070110988

申请日：2007-11-01

Applicant: 한국과학기술원

Inventor： 박제균 ,  김민석 ,  배채윤 ,  위갑인 ,  이정민 ,  한용만 ,  이영훈

IPC: G01N35/00 ,  A61D1/02 ,  A61D19/00

Abstract: An enucleation system of oocyte or ovum based on microfluid mechanics and an enucleation method of oocyte or ovum using the same are provided to perform single cells manipulation and to perform automatically and efficiently the enucleation of oocyte or ovum and to ensure high convenience and effectiveness of the stem cell and embryology research. An enucleation system of oocyte or ovum comprises oocyte or ovum culture medium and reagent inlet port(1); a microfluid channel part(7); and an envelope incision microfluidic channel part(10) reducing the diameter of an ovum movement microfluidic channel part; an ovum squeeze microfluidic channel part(16); an enucleated oocyte or the ovum vent(50); and a necleus vent(51) separated from oocyte or ovum.

Abstract translation: 提供基于微流体力学的卵母细胞或卵的摘除系统和使用其的卵母细胞或卵的摘除方法，以执行单细胞操作并自动和有效地执行卵母细胞或卵子的摘除，并确保高效的方便和有效性 干细胞和胚胎学研究。 卵母细胞或卵子的摘除系统包括卵母细胞或卵子培养基和试剂入口（1）; 微流体通道部分（7）; 和包膜切口微流体通道部分（10），其减小卵移动微流体通道部分的直径; 卵子挤压微流体通道部分（16）; 去核卵母细胞或排卵孔（50）; 和从卵母细胞或卵子分离出的心脏通气口（51）。

公开(公告)号：KR101804957B1

公开(公告)日：2018-01-10

申请号：KR1020160102605

申请日：2016-08-11

Applicant: 한국과학기술원

Inventor： 이영훈 ,  박근우 ,  이정민 ,  석신애 ,  김다운 ,  이지영 ,  김광선 ,  최병석

IPC: C12N15/113 ,  C12N15/63

CPC classification number: C12N15/113 ,  C12N15/63

Abstract: 본발명은미생물의생물막형성을조절할수 있는 sRNA를발현하는뉴클레오타이드를포함하는미생물의생물막형성조절용조성물, 상기뉴클레오타이드를포함하는재조합벡터, 상기재조합벡터로형질전환된형질전환세포및 상기재조합벡터를미생물에형질전환하는단계를포함하는미생물의생물막형성조절방법에관한것이다.

Abstract translation: 本发明微生物的重组载体，转化有重组载体细胞和重组载体生物膜形成用于调节含有表达的sRNA的核苷酸，可以控制含有核苷酸的微生物的生物膜形成微生物的组合物改变了开关 以及一种控制微生物生物膜形成的方法。

公开(公告)号：KR101207274B1

公开(公告)日：2012-12-03

申请号：KR1020100107555

申请日：2010-11-01

Applicant: 한국과학기술원

Inventor： 김양한 ,  박진영 ,  장지호 ,  송민호 ,  이정민 ,  이태웅

IPC: G11B20/10 ,  G11B27/34

Abstract: 본발명은음향재생장치에관한것이다. 본발명에따른음향재생장치는제1, 제2 및제3 음원신호를받아, 청취영역에서의음압레벨이청취영역이아닌영역에서의음압레벨보다높도록제1, 제2 및제3 음원신호의크기와위상을제어하여, 제1, 제2 및제3 제어음원신호를출력하는제어수단; 제1 제어음원신호를받아음향을재생하는제1 스피커; 제2 제어음원신호를받아음향을재생하는제2 스피커; 및제3 제어음원신호를받아음향을재생하는제3 스피커를포함하고, 상기제1, 제2 및제3 스피커는원형으로배열되며, 상기원형으로배열된상기제1, 제2 및제3 스피커의하방에상기청취영역이위치되어있다.

公开(公告)号：KR1020130013675A

公开(公告)日：2013-02-06

申请号：KR1020110075419

申请日：2011-07-28

Applicant: 한국과학기술원

Inventor： 이영훈 ,  이정민 ,  정의한 ,  김영미 ,  신희권

IPC: C12N15/11 ,  A61K48/00 ,  A61K31/7105 ,  A61P35/00

Abstract: PURPOSE: An siRNA which suppresses BC200 RNA activation and a pharmaceutical composition containing the same for suppressing tumor metastasis are provided to inhibit cancer cell migration and metastasis and to effectively treat cancer. CONSTITUTION: An siRNA which suppresses BC200 RNA(sequence number 1) activation has a base sequence of 5'-GUAACUUCCCUCAAAGCAA-3'(sequence number 2) or 5'- UUGCUUUGAGGGAAGUUAC-3'(sequence number 3). The siRNA additionally contains a dTdT base sequence at the 3'-end of the siRNA. A vector contains a polynucleotide which enables transcription of shRNA. The vector transcribes shRNA in a cell and the transcribed shRNA is converted into siRNA by cleavage using RNase III. A pharmaceutical composition for suppressing tumor metastasis contains the vector as an active ingredient. The composition additionally contains a pharmaceutically acceptable carrier. [Reference numerals] (AA) Negative control group siRNA

Abstract translation: 目的：提供抑制BC200 RNA活化的siRNA和抑制肿瘤转移的药物组合物，以抑制癌细胞迁移和转移并有效治疗癌症。 构成：抑制BC200 RNA（序列号1）活化的siRNA具有5'-GUAACUUCCCUCAAAGCAA-3'（序列号2）或5'UUGCUUGAGGGAAGUUAC-3'（序列号3）的碱基序列。 siRNA另外在siRNA的3'端含有dTdT碱基序列。 载体含有能够转录shRNA的多核苷酸。 载体在细胞中转录shRNA，转录的shRNA通过使用核糖核酸酶III的切割转化成siRNA。 用于抑制肿瘤转移的药物组合物含有作为活性成分的载体。 该组合物另外含有药学上可接受的载体。 （AA）阴性对照组siRNA

公开(公告)号：KR1020120045771A

公开(公告)日：2012-05-09

申请号：KR1020100107555

申请日：2010-11-01

Applicant: 한국과학기술원

Inventor： 김양한 ,  박진영 ,  장지호 ,  송민호 ,  이정민 ,  이태웅

IPC: G11B20/10 ,  G11B27/34

CPC classification number: G11B20/10481 ,  H04R5/02

Abstract: PURPOSE: A sound reproducing device is provided to grasp a transfer function considering features of a sound space, thereby enabling a user to obtain a sound signal optimized for generating a listening area. CONSTITUTION: The higher a sound pressure level of a listening area is than other areas except for the listening area, the more first, second, and third control sound signals a control unit outputs by controlling the amplitudes and phases of the first, second, and third sound signals. A first speaker(111) reproduces a sound by receiving the first control sound signal. A second speaker(112) reproduces a sound by receiving the second control sound signal. A third speaker(113) reproduces a sound by receiving the third control sound signal.

Abstract translation: 目的：提供一种考虑声音空间特征的传递函数的声音再现装置，从而使得用户能够获得优化以产生收听区域的声音信号。 构成：监听区域的声压级别除了听觉区域以外的其他区域越高，控制单元通过控制第一，第二和第三控制声音信号的幅度和相位来输出越多的第一，第二和第三控制声音信号， 第三声音信号。 第一扬声器（111）通过接收第一控制声音信号再现声音。 第二扬声器（112）通过接收第二控制声音信号再现声音。 第三扬声器（113）通过接收第三控制声音信号再现声音。

公开(公告)号：KR1020110064447A

公开(公告)日：2011-06-15

申请号：KR1020090121063

申请日：2009-12-08

Applicant: 한국과학기술원

Inventor： 박영진 ,  황성목 ,  강옥현 ,  최형렬 ,  김성훈 ,  이정민 ,  노지인 ,  권기진 ,  여승균

IPC: G10H3/12

Abstract: PURPOSE: A performance apparatus is provided to output the sound of corresponding musical instrument according to the performance operation of a player. CONSTITUTION: A handle(200) is connected to a ring(100). A stick(300) strikes a virtual plane. The virtual plane is defined by the circumference of the ring. A storage unit(500) stores a sound source for the musical instrument of a plurality of kinds. According to the relative position relation of the ring, the handle, and the hand of the player, a controller(400) selects one sound source of the musical instrument. An output unit(600) outputs the sound of one musical instrument.

Abstract translation: 目的：提供演奏装置，以根据演奏者的演奏操作输出相应乐器的声音。 构成：手柄（200）连接到环（100）。 棒（300）撞击虚拟飞机。 虚拟平面由环的圆周限定。 存储单元（500）存储用于多种乐器的声源。 根据环，手柄和玩家的手的相对位置关系，控制器（400）选择乐器的一个声源。 输出单元（600）输出一个乐器的声音。