Abstract:
The present invention discloses an anti-inflammation composition and an atopic dermatitis alleviation composition using an extract of immature fruits of Diospyros kaki. Specifically, disclosed are an anti-inflammation composition and an atopic dermatitis alleviation composition using an extract of immature fruits of Diospyros kaki, which have activity of inhibiting production of NO, PGE2, inflammatory cytokine, etc. in macrophages stimulated with LPS and inhibiting production of MDC and TARC in HaCaT cells which is a keratinocyte cell line processed with hIFN-γ and TNF-α.
Abstract:
The present invention discloses an anti-inflammatory composition and a composition for alleviation of atopic dermatitis using an extract from immature fruits of Diospyros kaki. Particularly, disclosed are an anti-inflammatory composition and a composition for alleviation of atopic dermatitis using an extract from immature fruits of Diospyros kaki, having the activity of inhibiting the generation of NO, PGE_2, inflammatory cytokines, etc. in LPS-stimulated macrophages and having the activity of inhibiting the generation of MDC and TARC in HaCaT cells which are a keratinocyte cell line treated with hIFN-gamma and TNF-alpha.