公开(公告)号：WO2021002910A1

公开(公告)日：2021-01-07

申请号：PCT/US2020/026844

申请日：2020-04-06

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： ZHANG, Shaoyi ,  TANG, Sadie ,  MYERS, Carl ,  XU, Guofeng

IPC: A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61Q11/00

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

公开(公告)号：WO2020033661A1

公开(公告)日：2020-02-13

申请号：PCT/US2019/045674

申请日：2019-08-08

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： HUANG, Chun ,  XU, Guofeng

IPC: A61K8/49 ,  A61Q11/00

Abstract: A whitening composition, an oral care product including the whitening composition, and a method for whitening teeth are disclosed. The whitening composition may include an anhydrous component and an aqueous component. The anhydrous component may include a base gel and a chloroisocyanurate. The chloroisocyanurate may be present in the anhydrous component in an amount of from about 0.01 weight % to about 30 weight %, based on a totally weight of the anhydrous component. The anhydrous component may include water.

公开(公告)号：WO2019032082A1

公开(公告)日：2019-02-14

申请号：PCT/US2017/045661

申请日：2017-08-07

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： HUANG, Chun ,  XU, Guofeng ,  DOGO-ISONAGIE, Cajetan

IPC: A61K8/362 ,  A61Q11/00 ,  A61K8/22 ,  A61K8/19

Abstract: A whitening composition and methods for whitening teeth and generating a whitening agent with the same are provided. The whitening composition may include an orally acceptable vehicle, a source of hydrogen peroxide that provides hydrogen peroxide, and a cyclic anhydride that generates a whitening agent with the hydrogen peroxided provided by the source of hydrogen peroxide. The whitening agent may be a peracid, such as a succinic peracid.

公开(公告)号：WO2018132522A1

公开(公告)日：2018-07-19

申请号：PCT/US2018/013242

申请日：2018-01-11

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： DONG, Rong ,  XU, Guofeng

IPC: A61K8/34 ,  A61Q11/00 ,  A61K8/81 ,  A61K8/22

Abstract: A tooth whitening composition includes a hydrophobic copolymer, a hydrophilic whitening agent and a polar solvent.

公开(公告)号：WO2018118552A1

公开(公告)日：2018-06-28

申请号：PCT/US2017/065972

申请日：2017-12-13

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： HASSAN, Mahmoud ,  CHEN, Xiang ,  PILLAI, Shyamala ,  XU, Guofeng ,  KILPATRICK-LIVERMAN, LaTonya ,  CHOPRA, Suman ,  DICOSIMO, Robert ,  PAYNE, Mark S.

IPC: A61K8/31 ,  A61K8/37 ,  A61K8/44 ,  A61K8/49 ,  A61K8/66 ,  A61Q11/00 ,  A61K8/81 ,  A61K8/22

Abstract: A two-phase oral care whitening composition including a hydrophobic phase and a hydrophilic phase, and methods for oral care whitening teeth with the same are provided. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor. The hydrophilic phase may include an enzyme that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor. At least one of the hydrophobic phase and the hydrophilic phase may further include at least one surfactant.

公开(公告)号：WO2018118496A1

公开(公告)日：2018-06-28

申请号：PCT/US2017/065683

申请日：2017-12-12

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： YUAN, Shaotang ,  XU, Guofeng ,  DICOSIMO, Robert ,  HAYNIE, Sharon

IPC: A61Q11/00 ,  A61K8/37 ,  A61K8/81 ,  A61K8/90

Abstract: An oral care composition, including a non-aqueous dispersant and an amphiphilic copolymer structure-building agent.

公开(公告)号：WO2017106073A1

公开(公告)日：2017-06-22

申请号：PCT/US2016/066082

申请日：2016-12-12

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： LAVENDER, Stacey ,  XU, Guofeng ,  DOGO-ISONAGIE, Cajetan

IPC: A61K8/23 ,  A61K8/02 ,  A61K8/81 ,  A61K8/19 ,  A61K8/365 ,  A61Q11/00

CPC classification number: A61K8/463 ,  A61K8/0204 ,  A61K8/022 ,  A61K8/19 ,  A61K8/23 ,  A61K8/36 ,  A61K8/365 ,  A61K8/8176 ,  A61K8/86 ,  A61K2800/222 ,  A61K2800/31 ,  A61K2800/594 ,  A61K2800/882 ,  A61Q11/00

Abstract: A solid composition for adding to water of an aqueous solution to form a whitening mouthrinse. The solid composition can be in the form of a tablet and contains a salt of peroxymonosulfate as a whitening agent.

Abstract translation: 用于向水溶液中加入水以形成美白漱口水的固体组合物。 固体组合物可以是片剂形式，并含有过氧单硫酸盐作为增白剂。

公开(公告)号：WO2017079686A1

公开(公告)日：2017-05-11

申请号：PCT/US2016/060715

申请日：2016-11-04

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： DONG, Rong ,  XU, Guofeng ,  YUAN, Shaotang ,  THOMAS, James ,  FRASER, Kevern

IPC: A61C19/06 ,  A61C5/62

CPC classification number: A61C19/063 ,  A61C3/005 ,  A61C5/62 ,  A61C19/066 ,  A61K6/0017 ,  A61K6/0091 ,  A61K6/0094 ,  A61K6/0215 ,  A61K6/0235 ,  A61M11/006

Abstract: Disclosed is a method of forming a uniform coating onto a tooth surface, which method includes: forming droplets by spraying an orally acceptable coating material through a spray nozzle, wherein the droplets have a volume-averaged droplet size of about 1 µm to about 100 µm, wherein a spray including the droplets travels from a tip of the spray nozzle towards the tooth surface at a spray rate of less than about 10 milliliters/minute and wherein the droplets include a film-forming polymer, a therapeutic agent and/or a cosmetic agent; and depositing the droplets onto the tooth surface to thereby form a uniform coating.

Abstract translation: 公开了一种在牙齿表面上形成均匀涂层的方法，所述方法包括：通过喷雾口腔可接受的涂层材料通过喷嘴形成液滴，其中所述液滴具有体积平均的液滴尺寸 其中包括液滴的喷雾以小于约10毫升/分钟的喷射速率从喷嘴的尖端朝向牙齿表面传播，并且其中液滴包括膜 形成聚合物，治疗剂和/或美容剂; 并将液滴沉积到牙齿表面上，从而形成均匀的涂层。

公开(公告)号：WO2017079668A1

公开(公告)日：2017-05-11

申请号：PCT/US2016/060692

申请日：2016-11-04

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： DONG, Rong ,  XU, Guofeng ,  YUAN, Shaotang

IPC: A61K8/81 ,  A61Q11/02 ,  A61K8/02 ,  A61K8/29

CPC classification number: A61K8/8164 ,  A61K8/0216 ,  A61K8/29 ,  A61K8/8158 ,  A61K8/97 ,  A61K2800/594 ,  A61Q11/00 ,  A61Q11/02

Abstract: Disclosed is a durable dental film-forming composition including an acrylate/octylacrylamide copolymer, wherein the acrylate/octylacrylamide copolymer is present in an amount of about 0.1% to about 50% by weight, an adhesive, and an orally acceptable solvent. Methods of using the composition are also disclosed.

Abstract translation: 公开了一种耐用牙科成膜组合物，其包含丙烯酸酯/辛基丙烯酰胺共聚物，其中丙烯酸酯/辛基丙烯酰胺共聚物以约0.1重量％至约50重量％的量存在，粘合剂和 口腔可接受的溶剂。 也公开了使用该组合物的方法。

公开(公告)号：WO2016144326A1

公开(公告)日：2016-09-15

申请号：PCT/US2015/019598

申请日：2015-03-10

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： DEMAREST, Scott ,  XU, Guofeng ,  MOSKOVICH, Robert

IPC: B65D35/22 ,  B65D35/24 ,  B65D35/28 ,  B65D47/10 ,  A61C9/00 ,  B05C17/005

CPC classification number: B65D81/325 ,  A61C9/0026 ,  A61C19/063 ,  A61C19/066 ,  B05C17/00553 ,  B05C17/00583 ,  B05C17/01 ,  B65D35/22 ,  B65D35/242 ,  B65D35/285 ,  B65D35/30 ,  B65D35/38 ,  B65D47/10 ,  B65D81/3266

Abstract: Provided is product dispenser that may be used for oral care products that are composed of two different ingredients that are mixed together prior to being used. The oral care product dispenser may include at least two storage chambers, a mixing chamber, a dispensing nozzle in fluidic communication with the mixing chamber and at least one seal that keeps the contents stored in the at least two storage chambers separated during storage. The mixing chamber receives and mixes contents from the at least two storage chambers during dispensing.

Abstract translation: 提供了可以用于口腔护理产品的产品分配器，其由在使用之前混合在一起的两种不同成分组成。 所述口腔护理产品分配器可以包括至少两个储存室，混合室，与所述混合室流体连通的分配喷嘴和至少一个密封件，其将储存在所述至少两个储存室中的内容物在储存期间分开。 在分配期间，混合室接收并混合来自至少两个储存室的内容物。