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    SYSTEMS AND METHODS FOR ANALYZING BIOPOTENTIAL MORPHOLOGIES IN BODY TISSUE
    61.
    发明申请
    SYSTEMS AND METHODS FOR ANALYZING BIOPOTENTIAL MORPHOLOGIES IN BODY TISSUE 审中-公开
    用于分析身体组织中生物力学形态的系统和方法

    公开(公告)号：WO1996025094A1

    公开(公告)日：1996-08-22

    申请号：PCT/US1996002034

    申请日：1996-02-16

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin ,  WHAYNE, James, G.

    IPC: A61B05/0402

    CPC classification number: A61N1/403 ,  A61B1/0051 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/6855 ,  A61B5/6858 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056

    Abstract: Systems and methods analyze bio-potential morphologies in body tissue. The systems and methods use a template of a bio-potential event of known cause in body tissue. The systems and methods compare this template to a sample of a bio-potential event externally triggered in body tissue. The systems and methods generate an output based upon this comparison. The systems and methods can be used to compare an event specific to the template of a cardiac event (T(i)) of known diagnosis to a sample of a placed cardiac event (P(i)). The comparison yields a matching coefficient (MCOEFF(i)) indicating how alike the input sample is to the input template. The matching coefficient can be used by the physician, for example, to aid in the location of sites that are potentially appropriate for ablation.

    Abstract translation: 系统和方法分析身体组织中的生物潜能形态。 系统和方法使用身体组织中已知原因的生物潜在事件的模板。 系统和方法将此模板与身体组织中外部触发的生物潜在事件的样本进行比较。 系统和方法基于此比较生成输出。 系统和方法可以用于将已知诊断的心脏事件（T（i））的模板特有的事件与放置的心脏事件（P（i））的样本进行比较。 比较产生一个匹配系数（MCOEFF（i）），表示输入样本与输入模板的相似度。 例如，医生可以使用匹配系数来帮助可能适合于消融的部位的位置。

    FLEXIBLE STRUCTURES FOR SUPPORTING ELECTRODE ELEMENTS
    62.
    发明申请
    FLEXIBLE STRUCTURES FOR SUPPORTING ELECTRODE ELEMENTS 审中-公开
    支持电极元件的柔性结构

    公开(公告)号：WO1996010961A1

    公开(公告)日：1996-04-18

    申请号：PCT/US1995013128

    申请日：1995-10-06

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  FLEISCHMAN, Sidney, D. ,  WHAYNE, James, G. ,  BOURNE, Thomas, M. ,  SWANSON, David, K.

    IPC: A61B17/39

    CPC classification number: A61N1/056 ,  A61B18/14 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2017/00243 ,  A61B2018/00083 ,  A61B2018/00148 ,  A61B2018/00178 ,  A61B2018/00214 ,  A61B2018/00916 ,  A61B2018/00946 ,  A61B2018/00952 ,  A61B2018/00988 ,  A61B2018/1407 ,  A61B2018/142

    Abstract: An electrode support structure has a guide body (12) having a distal end and a stylet (80) having a bendable portion extending along an axis outside the distal end of the guide body (12). The structure also includes at least one flexible spline leg (22) having a body and a far end extending beyond the distal end of the guide body (12) and attached to the bendable portion of the stylet (80). The spline leg (22) is normally flexed between the distal guide body end and the bendable stylet portion in a first direction that extends along and radially outward of the axis of the stylet (80). At least one electrode element (28) is on the flexible spline leg (22). The bendable stylet portion (80) applies tension to flex the spline leg (22) in a second direction.

    Abstract translation: 电极支撑结构具有具有远端的引导体（12）和具有沿着引导体（12）的远端外侧的轴线延伸的弯曲部分的探针（80）。 该结构还包括至少一个柔性花键腿（22），其具有主体和延伸超过引导体（12）的远端的远端并且附接到通球针（80）的可弯曲部分。 花键腿（22）通常沿着沿通孔（80）的轴线并且径向向外延伸的第一方向在远侧引导体端部和可弯曲的探针部分之间弯曲。 至少一个电极元件（28）在柔性花键腿（22）上。 可弯曲的探针部分（80）施加张力以在第二方向上挠曲花键腿部（22）。

    DETERMINING PROPAGATION VELOCITIES OF HEART ELECTRICAL EVENTS
    64.
    发明申请
    DETERMINING PROPAGATION VELOCITIES OF HEART ELECTRICAL EVENTS 审中-公开
    确定心脏电活动的传播速度

    公开(公告)号：WO1995020420A1

    公开(公告)日：1995-08-03

    申请号：PCT/US1995001114

    申请日：1995-01-27

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin

    IPC: A61N01/04

    CPC classification number: A61B5/0538 ,  A61N1/056

    Abstract: Systems and methods examine heart tissue morphology by locating electrodes (38) in contact with a region of heart tissue to sense the timing of a local depolarization event. From this, the systems and methods derive the propagation velocities of the depolarization events and create an output (246) that displays the derived propagation velocities in spatial relation to the sensing electrodes. The systems (246) and methods then arrange the derived propagation velocities into groups of equal propagation velocities and generate three-dimensional outputs of the groups of equal propagation velocity in spatial relation to the location of the sensing electrodes. The iso-conduction display more rapidly identifies the regions of slow conduction which are candidate ablation sites.

    Abstract translation: 系统和方法通过定位与心脏组织区域接触的电极（38）来检测心脏组织形态，以感测局部去极化事件的定时。 从此，系统和方法导出去极化事件的传播速度，并创建一个输出（246），显示与传感电极的空间关系的导出传播速度。 系统（246）和方法然后将导出的传播速度安排成相等传播速度的组，并且产生与感测电极的位置在空间关系中的相等传播速度的组的三维输出。 等电导显示更快速地识别作为候选消融部位的慢传导区域。

    MATCHING ELECTRICAL CHARACTERISTICS AND PROPAGATION VELOCITIES TO LOCATE ABLATION SITES
    65.
    发明申请
    MATCHING ELECTRICAL CHARACTERISTICS AND PROPAGATION VELOCITIES TO LOCATE ABLATION SITES 审中-公开
    匹配电气特征和传播速度来定位消除场地

    公开(公告)号：WO1995020348A1

    公开(公告)日：1995-08-03

    申请号：PCT/US1995001122

    申请日：1995-01-27

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  SWANSON, David, K.

    IPC: A61B05/04

    CPC classification number: A61B18/00 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/0538 ,  A61B5/6855 ,  A61B5/6858 ,  A61B18/14 ,  A61B2562/0209 ,  A61B2562/043

    Abstract: Systems (10) and methods examine heart tissue morphology for the purpose of locating a potential ablation site. The systems and methods derive the electrical characteristic of tissue lying between the electrode pairs (38) based, at least in part, upon sensing tissue impedances. The systems and methods also sense the timing of local depolarization events in the tissue in which impedance is sensed and derive therefrom the propagation velocities of the sensed depolarization events. The systems and methods match the derived tissue electrical characteristics with the derived propagation velocities in spatial relation to the electrodes to characterize the morphology of the contacted heart tissue to identify a potential ablation site.

    Abstract translation: 系统（10）和方法检查心脏组织形态，以定位潜在的消融部位。 系统和方法至少部分地基于感测组织阻抗而导出位于电极对（38）之间的组织的电特性。 系统和方法还感测组织中局部去极化事件的定时，其中阻抗被感测并从其导出感测去极化事件的传播速度。 系统和方法将衍生的组织电特征与衍生的与电极空间关系的传播速度相匹配，以表征所接触的心脏组织的形态以鉴定潜在的消融部位。

    LOCATING AND ABLATING PATHWAYS IN THE HEART
    70.
    发明申请
    LOCATING AND ABLATING PATHWAYS IN THE HEART 审中-公开
    在心中定位和解放路

    公开(公告)号：WO1995010226A1

    公开(公告)日：1995-04-20

    申请号：PCT/US1994011495

    申请日：1994-10-12

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  McGEE, David, L. ,  HOUSER, Russell, A. ,  SWANSON, David, K.

    IPC: A61B05/04

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/6857 ,  A61B5/6858 ,  A61B18/1492 ,  A61B2017/003 ,  A61B2018/00107 ,  A61B2018/00148 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2018/1861 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056 ,  A61N1/06 ,  A61N1/3686 ,  A61N1/403

    Abstract: Systems and methods sense electrical events about a selected annulus region (26, 30) of the heart (10) to identify the location of an accessory pathway. They establish a contact site between heart tissue and a multi-electrode array (E1-E10) conforming to the circumferential geometry of the selected annulus region (26, 30). The system and methods maintain this site, while conveying signals representing electrical events sensed by bipolar pairs of the electrodes (E1-E10). The systems and methods display the signals as graphic information that represents the time differences (T1, T2) between the atrium (A) and ventricular (V) electrogram complexes sensed by the pairs (E1-E10) on the selected annulus region (26, 30). The pairs (E1-E10) displaying the least time separation between the complexes (A, V) identifies the region of the accessory pathway. With this information, energy is conveyed to the electrodes of the selected pair to ablate tissue.

    Abstract translation: 系统和方法检测关于心脏（10）的选定环区（26,30）的电事件，以识别附件通路的位置。 它们在心脏组织和符合所选择的环空区域（26,30）的圆周几何形状的多电极阵列（E1-E10）之间建立接触位置。 系统和方法维护该站点，同时传送表示由双极电极对（E1-E10）感测的电气事件的信号。 所述系统和方法将所述信号显示为图形信息，所述图形信息表示由所选择的环面区域（26）上的对（E1-E10）感测的心房（A）和心室（V）电描绘图复合体之间的时间差（T1，T2） 30）。 在复合体（A，V）之间显示最小时间间隔的对（E1-E10）标识附件通路的区域。 利用该信息，将能量传送到所选择的对的电极以烧蚀组织。

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