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公开(公告)号：NO941679L
公开(公告)日：1994-11-09
申请号：NO941679
申请日：1994-05-06
Applicant: HOECHST AG
Inventor： WESS GUNTHER , ENHSEN ALFONS , GLOMBIK HEINER , KRAMER WERNER
IPC: A61K31/575 , A61P3/06 , A61P43/00 , C07J9/00 , C07J41/00
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公开(公告)号：NO941679A
公开(公告)日：1994-11-09
申请号：NO941679
申请日：1994-05-06
Applicant: HOECHST AG
Inventor： WESS GUNTHER , ENHSEN ALFONS , GLOMBIK HEINER , KRAMER WERNER
IPC: A61K31/575 , A61P3/06 , A61P43/00 , C07J9/00 , C07J41/00
CPC classification number: C07J41/0088 , C07J9/005 , C07J41/0005 , C07J41/0011 , C07J41/0055 , C07J41/0061
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公开(公告)号：NO941678A
公开(公告)日：1994-11-09
申请号：NO941678
申请日：1994-05-06
Applicant: HOECHST AG
Inventor： ENHSEN ALFONS , GLOMBIK HEINER , KRAMER WERNER , WESS GUNTHER
IPC: A61K31/575 , A61P3/06 , A61P9/00 , C07J3/00 , C07J7/00 , C07J9/00 , C07J31/00 , C07J41/00 , C07J51/00
CPC classification number: C07J3/005 , C07J3/00 , C07J7/0005 , C07J7/002 , C07J7/007 , C07J9/005 , C07J31/006 , C07J41/0005 , C07J41/0011 , C07J41/0027 , C07J41/0061 , C07J41/0066 , C07J41/0088 , C07J41/0094 , C07J51/00
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公开(公告)号：NO175637C
公开(公告)日：1994-11-09
申请号：NO893167
申请日：1989-08-04
Applicant: HOECHST AG
Inventor： BECK GERHARD , BARTMANN WILHELM , WESS GUNTHER , GRANZER ERNOLD
IPC: A61K31/19 , A61K31/215 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/44 , A61K31/4406 , A61K31/4418 , A61K31/443 , A61K31/4433 , A61K31/50 , A61K31/505 , A61P3/06 , A61P9/10 , A61P43/00 , C07C27/00 , C07C29/147 , C07C33/48 , C07C45/56 , C07C47/55 , C07C59/56 , C07C67/00 , C07C67/31 , C07C67/343 , C07C69/65 , C07C69/732 , C07C69/738 , C07D207/32 , C07D207/333 , C07D207/337 , C07D213/30 , C07D213/48 , C07D213/55 , C07D213/79 , C07D237/08 , C07D239/26 , C07D307/54 , C07D309/30 , C07D333/24 , C07D405/06 , C07D407/06 , C07D409/06
Abstract: 6-Fluoro-3,5-dihydroxy carboxylic acid derivatives of the formula I and the corresponding lactones of the formula II in which R1 and R2 have the specified meanings, a process for the preparation of these compounds, the use thereof as medicinal agents and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formula I or formula II are described.
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公开(公告)号：AU6189294A
公开(公告)日：1994-07-21
申请号：AU6189294
申请日：1994-05-04
Applicant: HOECHST AG
Inventor： WEITHMANN KLAUS-ULRICH , WESS GUNTHER , SEIFFGE DIRK
IPC: A61K31/35 , A61K31/352 , A61P9/00 , C07D311/58 , C07D311/66 , C07D319/06 , C07D339/00 , C07D339/04 , C07D339/08 , C07F9/655 , C07F9/6558 , C07J9/00 , C07J11/00 , C07J17/00 , C07J31/00 , C07J33/00 , C07J41/00 , C09K15/04 , A61K31/58 , A61K31/165 , A61K31/57 , A61K31/05 , A61K31/23 , C07F9/40 , A23L3/349 , A23L3/3544 , C07D307/62
Abstract: Lipid-selective antioxidants of the general formula I (A)a(L)(X)a(I> in which A = antioxidant component, L = linker, X = lipophilic component, a and a' = independently of one another the numbers 1 or 2. The compounds are used to protect lipid-containing substances from oxidation and in pharmaceutical compositions for the prophylaxis and therapy of diseases in which bioradicals are involved, in particular diseases of the heart, circulation and vessels.
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Patent Agency Ranking
公开(公告)号：NO941677D0
公开(公告)日：1994-05-06
申请号：NO941677
申请日：1994-05-06
Applicant: HOECHST AG
Inventor： ENHSEN ALFONS , GLOMBIK HEINER , KRAMER WERNER , WESS GUNTHER
IPC: A61K31/575 , A61K31/58 , A61K31/675 , A61P3/06 , A61P9/10 , C07J9/00 , C07J17/00 , C07J41/00 , C07J43/00
Abstract: Tetrazole bile acid derivatives of the formula I G1 - X - G2 I in which G1, G2 and X have the stated meanings, and processes for their preparation are described. The compounds have valuable pharmacological properties and can therefore be used as medicines.
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公开(公告)号：NZ230217A
公开(公告)日：1991-12-23
申请号：NZ23021789
申请日：1989-08-04
Applicant: HOECHST AG
Inventor： BECK GERHARD , BARTMANN WILHELM , WESS GUNTHER , GRANZER ERNOLD
IPC: A61K31/19 , A61K31/215 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/44 , A61K31/4406 , A61K31/4418 , A61K31/443 , A61K31/4433 , A61K31/50 , A61K31/505 , A61P3/06 , A61P9/10 , A61P43/00 , C07C27/00 , C07C29/147 , C07C33/48 , C07C45/56 , C07C47/55 , C07C59/56 , C07C67/00 , C07C67/31 , C07C67/343 , C07C69/65 , C07C69/732 , C07C69/738 , C07D207/32 , C07D207/333 , C07D207/337 , C07D213/30 , C07D213/48 , C07D213/55 , C07D213/79 , C07D237/08 , C07D239/26 , C07D307/54 , C07D309/30 , C07D333/24 , C07D405/06 , C07D407/06 , C07D409/06 , C07D213/26 , C07D207/08 , C07C47/24 , C07D309/20 , A61K31/23
Abstract: 6-Fluoro-3,5-dihydroxy carboxylic acid derivatives of the formula I and the corresponding lactones of the formula II in which R1 and R2 have the specified meanings, a process for the preparation of these compounds, the use thereof as medicinal agents and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formula I or formula II are described.
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公开(公告)号：AU6921791A
公开(公告)日：1991-09-05
申请号：AU6921791
申请日：1991-01-08
Applicant: HOECHST AG
Inventor： WEITHMANN KLAUS-ULRICH , WESS GUNTHER , SEIFFGE DIRK
IPC: A61K31/35 , A61K31/352 , A61P9/00 , C07D311/58 , C07D311/66 , C07D319/06 , C07D339/00 , C07D339/04 , C07D339/08 , C07F9/655 , C07F9/6558 , C07J9/00 , C07J11/00 , C07J17/00 , C07J31/00 , C07J33/00 , C07J41/00 , C09K15/04 , C07C235/50 , C07C49/835 , C07C69/738 , C07C43/178 , C09K15/08 , C09K15/24 , C07F9/40 , C07C323/52 , C07C69/88 , C07C69/732 , C07C39/11 , C07C59/52 , C07C61/22 , C07C69/157 , C07C323/12 , C07C323/60 , A61K31/575 , A61K31/165 , A61K31/05 , A61K31/385 , C07F9/11
Abstract: Lipid-selective antioxidants of the general formula I (A)a(L)(X)a(I> in which A = antioxidant component, L = linker, X = lipophilic component, a and a' = independently of one another the numbers 1 or 2. The compounds are used to protect lipid-containing substances from oxidation and in pharmaceutical compositions for the prophylaxis and therapy of diseases in which bioradicals are involved, in particular diseases of the heart, circulation and vessels.
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公开(公告)号：ZA9007300B
公开(公告)日：1991-06-26
申请号：ZA9007300
申请日：1990-09-13
Applicant: HOECHST AG
Inventor： KRAMER WERNER , WERNER KRAMER , WESS GUNTHER , GUNTHER WESS
IPC: A61K38/00 , A61K31/575 , A61K31/58 , A61P1/16 , A61P3/06 , A61P43/00 , C07D213/26 , C07D213/56 , C07D213/81 , C07J9/00 , C07J17/00 , C07J31/00 , C07J41/00 , C07J43/00 , C07J51/00 , C07K5/06 , C07K5/062 , C07J , A61K
CPC classification number: C07D213/81 , A61K38/00 , C07D213/26 , C07D213/56 , C07J9/005 , C07J17/00 , C07J31/006 , C07J41/0011 , C07J41/0027 , C07J41/0055 , C07J41/0061 , C07J41/0088 , C07J43/003 , C07J51/00 , C07K5/06026
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公开(公告)号：AU608868B2
公开(公告)日：1991-04-18
申请号：AU1929588
申请日：1988-07-22
Applicant: HOECHST AG
Inventor： WESS GUNTHER , BARTMANN WILHELM , BECK GERHARD , ANAGNOSTOPULOS HIRISTO
IPC: A61K31/38 , A61K31/085 , A61K31/10 , A61K31/12 , A61K31/165 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/34 , A61K31/381 , A61K31/395 , A61K31/41 , A61K31/44 , A61K31/535 , A61K31/5375 , A61P1/04 , A61P11/00 , A61P17/00 , A61P29/00 , A61P37/08 , A61P43/00 , C07C41/00 , C07C43/00 , C07C43/178 , C07C43/20 , C07C43/235 , C07C43/263 , C07C45/00 , C07C47/52 , C07C49/84 , C07C51/00 , C07C59/125 , C07C65/21 , C07C67/00 , C07C69/007 , C07C69/025 , C07C69/675 , C07C69/92 , C07C201/00 , C07C235/06 , C07C235/16 , C07C239/00 , C07C239/14 , C07C313/00 , C07C317/00 , C07C317/04 , C07C317/18 , C07C317/22 , C07C317/24 , C07C317/44 , C07C317/46 , C07C323/00 , C07C323/16 , C07C323/19 , C07C323/22 , C07C323/52 , C07C323/56 , C07C323/60 , C07C323/65 , C07D213/30 , C07D257/04 , C07D295/18 , C07D317/36 , C07D317/38 , C07D333/16 , C07C149/273 , C07C147/14 , A61K31/185 , A61K31/255 , C07C147/10
Abstract: Leukotriene antagonists, a process for the preparation thereof, and the use thereof for the treatment of diseases (I) in which R1, R2, R3, R4, R5 and X have the indicated meanings, a process for the preparation of these compounds, the use thereof as pharmaceuticals, and pharmaceutical products based on these compounds, are described.
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