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公开(公告)号:US20170136485A1
公开(公告)日:2017-05-18
申请号:US15358446
申请日:2016-11-22
Applicant: Stamford Devices Limited
Inventor: Brendan Hogan , Daniela BUTAN , Seamus CLIFFORD , Michael POMEROY , Mark SOUTHERN , David SHEIL
CPC classification number: B05B17/0646 , B05B15/18 , B05B17/06 , B05B17/0653 , B05B17/0669
Abstract: An aperture plate is formed from a palladium nickel alloy comprising about 89% palladium and about 11% nickel. There is a generally fine substantially equiaxed grain microstructure throughout the thickness of the aperture plate. The average grain width (W) is in the range of from 0.2 μm to 5.0 μm, in some cases from 0.2 μm to 2.0 μm. Because the grain structure is equiaxed (L/W=1) the grain length (L) is the same as the grain width. The improved aperture plate extends the life of nebulisers, eliminates the risk of premature and unpredictable failure of a nebuliser in service, eliminates the risk of product returns from hospitals and patients, and eliminates the possible risk of fragments of the aperture plate breaking free from the nebulizer.
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公开(公告)号:US09522409B2
公开(公告)日:2016-12-20
申请号:US13720759
申请日:2012-12-19
Applicant: Stamford Devices Limited
Inventor: Brendan Hogan , Daniela Butan , Seamus Clifford , Michael Pomeroy , Mark Southern , David Sheil
CPC classification number: B05B17/0646 , B05B15/18 , B05B17/06 , B05B17/0653 , B05B17/0669
Abstract: An aperture plate is formed from a palladium nickel alloy comprising about 89% palladium and about 11% nickel. There is a generally fine substantially equiaxed grain microstructure throughout the thickness of the aperture plate. The average grain width (W) is in the range of from 0.2 μm to 5.0 μm, in some cases from 0.2 μm to 2.0 μm. Because the grain structure is equiaxed (L/W=1) the grain length (L) is the same as the grain width. The improved aperture plate extends the life of nebulizers, eliminates the risk of premature and unpredictable failure of a nebulizer in service, eliminates the risk of product returns from hospitals and patients, and eliminates the possible risk of fragments of the aperture plate breaking free from the nebulizer.
Abstract translation: 孔板由包含约89%钯和约11%镍的钯镍合金形成。 在孔板的整个厚度上存在通常细的基本上等轴晶粒微观结构。 平均晶粒宽度(W)在0.2μm至5.0μm的范围内,在某些情况下为0.2μm至2.0μm。 由于晶粒结构为等轴(L / W = 1),晶粒长度(L)与晶粒宽度相同。 改进的孔板延长了喷雾器的使用寿命,消除了雾化器在使用中过早和不可预测的故障的风险,消除了医院和患者返回产品的风险,并消除了孔板破碎的可能性。 喷雾器。
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公开(公告)号:US20130199529A1
公开(公告)日:2013-08-08
申请号:US13829044
申请日:2013-03-14
Applicant: STAMFORD DEVICES LIMITED
Inventor: John Sylvester Power , James B. Fink , Conor Paul Duffy , Trevor Stephen Fahy
CPC classification number: A61M16/14 , A61M11/002 , A61M11/003 , A61M11/005 , A61M15/0085 , A61M16/0057 , A61M16/0666 , A61M16/0672 , A61M16/0833 , A61M16/0875 , A61M16/147 , A61M16/16 , A61M2202/0208 , A61M2206/14 , B05B12/081 , B05B17/0646 , B05B17/0669
Abstract: A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.
Abstract translation: 描述了补充氧气输送系统,其中气溶胶被输送到壳体10,20中,壳体10,20从补充氧气供应和可选的加湿器位于电路中。 补充的氧通过其中所述气溶胶所在的腔室10,20,并收集通过鼻插管3或面罩4将其运送到患者的气溶胶。气溶胶发生器9安装到壳体10,20上, 将气溶胶递送到在壳体10的入口14和出口15之间流动的氧气流13.壳体10还具有在其底部17中的可移除的塞子16,用于排出积聚在壳体10中的任何液体。不存在中断 使用鼻塞的患者的氧气输送,当接受雾化药物时,目前必须使用单独的面罩。
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公开(公告)号:WO2022013089A1
公开(公告)日:2022-01-20
申请号:PCT/EP2021/069140
申请日:2021-07-09
Applicant: STAMFORD DEVICES LIMITED
Inventor: POWER, John , MACLOUGHLIN, Ronan , CASEY, Micheal , DUFFY, Conor , DUFFY, Aidan
IPC: A61M15/00
Abstract: A single dose aerosol chamber (110) is used with a dispensing apparatus (100) by users to take a chamber (110), fill the chamber with an aerosolized vaccine (104), and dispose of used chambers (120). A display (103) provides instructions to encourage prompt inhalation by the user from a dispensed and filled chamber. The station allows very fast administration of vaccines to large numbers of people. The aerosol dispenser apparatus detects the chamber is in correct position and delivers a pre-determined dose of aerosol. The chamber has a nebulizer delivery port (114) optimized for delivery of aerosol into the chamber container (111) and to act as a vent during inhalation via the inhalation port (115).
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公开(公告)号:WO2019038408A1
公开(公告)日:2019-02-28
申请号:PCT/EP2018/072824
申请日:2018-08-23
Applicant: STAMFORD DEVICES LIMITED
Inventor: GREHAN, Joseph , COYLE, Noel , GREANEY, Russell , THORNTON, Stephen
Abstract: An aerosol delivery system has an aerosol generator with a vibrating aperture plate (10) and an actuator (11, 16, 17, 19), a controller (18, 19). The controller in real time monitors (201) the aerosol generator as it is driven for vibration of the aperture plate, and detects (202) a change in an electrical characteristic in response to a transition from a wet state to a dry state of the aperture plate. It automatically modifies (203, 205, 206), during the transition, operation of the aerosol generator in response to the detected change. The modification includes reducing applied power (203). The controller continues (204) to monitor during the transition, including monitoring the aperture plate for presence of residual liquid on the aperture plate first surface. The controller monitors at a number of drive frequencies and maintains data representing trends in a combination of the electrical characteristic signals at the different frequencies, and identifies a start of a transition if a calculated value rises above a threshold. There is one threshold for triggering a check scan for residual volume and a higher threshold to trigger an immediate shut down.
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公开(公告)号:WO2015177311A1
公开(公告)日:2015-11-26
申请号:PCT/EP2015/061329
申请日:2015-05-21
Applicant: STAMFORD DEVICES LIMITED
Inventor: HOGAN, Brendan , XU, Hong
CPC classification number: B05B1/02 , A61M11/005 , A61M15/0085 , A61M2207/00 , B05B17/0638 , B05B17/0653 , C25D1/08 , C25D7/04
Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns (2) having a desired size, pitch, and profile, which yields a wafer about 60μιη thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal (3) overlies the top surfaces of the columns until the desired apertures (4) are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways (24) formed beneath the apertures (32), formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures (32).
Abstract translation: 通过在具有期望的尺寸,间距和轮廓的抗蚀剂柱(2)的掩模上镀覆金属来制造孔板,其产生约60μI厚度的晶片。 这大约是完全期望的目标孔板厚度。 继续进行电镀,使得金属(3)覆盖在柱的顶表面上,直到达到所需的孔(4)。 这只需要一个掩模/电镀周期来实现所需的板厚度。 此外,板具有形成在孔(32)下方的通道(24),其形成为该方法的组成部分,通过掩模材料去除。 这些适合于夹带离开孔(32)的雾化液滴。
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公开(公告)号:WO2022048927A1
公开(公告)日:2022-03-10
申请号:PCT/EP2021/073209
申请日:2021-08-20
Applicant: STAMFORD DEVICES LIMITED
Inventor: POWER, John , DUFFY, Aidan , CASEY, Micheal
Abstract: A patient interface (1) is for aerosol treatment, having a base (2) to surround the patient's mouth and nose and engage the skin with a resilient seal, and with a strap (8) to attach to a patient's head. There is a support (3) on and across the base for supporting an aerosol delivery head with prongs (4, 5). An enclosed volume is formed in the interface by attachment of a shell (10), which has an extraction port (11) for attachment of an extraction system (20) to extract gas from this volume. An HFNT system includes a patient interface surrounding the nose and mouth and an aerosol delivery apparatus (4, 6), an extraction apparatus (20), and a controller (100) to control delivery of aerosol and/or gas to the interface and to extract gases from a volume enclosed by the interface. Because of the fully sealed volume within the interface there are a wide range of control scenarios possible, using pressure sensing in the volume, bypass valves (201), dynamically-controllable nebulizer (203).
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公开(公告)号:WO2021191160A1
公开(公告)日:2021-09-30
申请号:PCT/EP2021/057304
申请日:2021-03-22
Applicant: STAMFORD DEVICES LIMITED
Inventor: CONNOLLY, Diarmuid , CARMODY, Colm , MAGUIRE, Finbarr , DUFFY, Aidan
IPC: B05B17/00 , A61M11/00 , A61M11/005 , A61M15/0085 , B05B17/0646
Abstract: A nebulizer (1) has an aerosol generator (5) mounted in a housing (3), and has a vibratable aperture plate (41) mounted to an annular support (40) and to which is attached a vibration generator piezo (46). A downstream annular resilient seal (43) is mounted between the housing and the washer (40) on a side of the aperture plate opposed to the liquid supply reservoir (21). An upstream resilient seal (48) is in the form of a gasket and is mounted between the washer (40) and the housing reservoir (21), and has an opening (72) forming part of a throat (8) over the aperture plate (41). The gasket (48) has a washer-shaped body (70) extending radially from a downstream-extending rim (71) adjacent the aperture plate (41). There are two upwardly-directed ridges (74, 75) for engagement with a housing (21) surface, and the gasket is configured so that when under axial compression the opening (72) internal surface is tapered inwardly in a flow direction to form a funnel shape. The gasket may be textured with sufficient surface roughness to deter bubbles from attaching to a surface exposed to the throat.
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公开(公告)号:WO2021023596A1
公开(公告)日:2021-02-11
申请号:PCT/EP2020/071390
申请日:2020-07-29
Applicant: STAMFORD DEVICES LIMITED
Inventor: POWER, Patrick , CASEY, Micheal , REDMOND, Anthony
Abstract: A nebuliser control device (1, 10) has a manually adjustable user interface (2, 12) and a cable (4) extending from the interface to a power source, and a cable (5) extending from the interface (2, 12) to an aerosol generator. The interface is manually adjustable by physical movement of an actuator such a slider (2) or a rotating knob (12) to locally control the operation of the aerosol generator.
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公开(公告)号:WO2020114603A1
公开(公告)日:2020-06-11
申请号:PCT/EP2018/083885
申请日:2018-12-06
Applicant: STAMFORD DEVICES LIMITED
Inventor: KERN, Stefan
Abstract: A coupling part with integrated aerosol generator for use in a breathing circuit, comprising a housing (10) enclosing a cavity (V), having a first opening at a first end prepared for direct or indirect connection to a ventilator, a second opening at a second end, which is suitable for direct or indirect connection to a patient line or an endotracheal tube, wherein an aerosol generator (20) is integrated in one side of the housing and is suitable for delivering an aerosolised liquid, in particular a medicament.
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