뉴캐슬병바이러스 HN 단백질 및 이를 포함하는 HI법 검사용 항원진단액
    72.
    发明公开
    뉴캐슬병바이러스 HN 단백질 및 이를 포함하는 HI법 검사용 항원진단액 有权
    新陈代谢病毒HN蛋白和含有其的新鲜病毒的诊断组合物

    公开(公告)号:KR1020130071693A

    公开(公告)日:2013-07-01

    申请号:KR1020110139057

    申请日:2011-12-21

    Abstract: PURPOSE: An HN protein of Newcastle disease virus (NDV) and an NDV antigen diagnostic liquid containing the same for a hemagglutination inhibition (HI) method are provided to quickly and cheaply produce the NDV antigen diagnostic liquid without contamination or disease infection. CONSTITUTION: A method for preparing a recombinant baculovirus expression vector comprises the steps of: isolating virus genome RNA from NDV Lasota strain; synthesizing cDNA of HN protein of NDV protein using a reverse primer of sequence number 2 and RNA; performing PCR of cDNA using a forward primer of sequence number 1, and a reverse primer of sequence number 2 to synthesize DNA; treating the synthesized DNA with Xba1 and Hind III, and extracting DNA fragments; and inserting the DNA fragment into a multicloning site of pFastBac TM 1 expression vector with baculovirus polyhedron promoter. [Reference numerals] (AA) Novel method; (BB) Conventional method; (CC) Normal cells

    Abstract translation: 目的:提供新城疫病毒(NDV)的HN蛋白和含有血细胞凝集抑制(HI)方法的NDV抗原诊断液,以快速,便宜地生产无污染或疾病感染的NDV抗原诊断液。 构成:制备重组杆状病毒表达载体的方法包括以下步骤:从NDV Lasota菌株中分离病毒基因组RNA; 使用序列号2和RNA的反向引物合成NDV蛋白的HN蛋白的cDNA; 使用序列号1的正向引物进行cDNA的PCR和序列号2的反向引物合成DNA; 用Xba1和Hind III处理合成的DNA,提取DNA片段; 并将DNA片段插入具有杆状病毒多面体启动子的pFastBac TM 1表达载体的多克隆位点。 (附图标记)(AA)新方法; (BB)常规方法; (CC)正常细胞

    새로운 약독형 유전아형의 뉴캣슬병 바이러스 백신주 및 이를 포함하는 뉴캣슬병 바이러스 백신
    77.
    发明公开
    새로운 약독형 유전아형의 뉴캣슬병 바이러스 백신주 및 이를 포함하는 뉴캣슬병 바이러스 백신 有权
    嗜酸性新生病毒病毒的新型疫苗菌株及其包含的病毒疫苗

    公开(公告)号:KR1020120006164A

    公开(公告)日:2012-01-18

    申请号:KR1020100066744

    申请日:2010-07-12

    CPC classification number: A61K39/17 C12N2760/18111

    Abstract: PURPOSE: A vaccine strain for Newcastle disease is provided to ensure safety to chickens and to improve immunity of chicken. CONSTITUTION: A vaccine strain for Newcastle disease is denoted by deposit number KCTC 11718BP. The vaccine strain belongs to a subtype of genotype I in phylogenetic systematic. The vaccine stain has affinity to chicken respirator and digestive organ. A vaccine for preventing Newcastle disease contains the vaccine strain. The vaccine is vaccinated to chickens by drinking, eye-dropping, or spraying. The vaccine is manufactured in a sub-unit vaccine, vector vaccine, chimera vaccine, or DNA vaccine. The vaccine contains acceptable medium or excipient and adjuvant.

    Abstract translation: 目的:提供新城疫疫苗株,以确保鸡只的安全,并提高鸡的免疫力。 构成:新城疫疫苗株由保藏号KCTC 11718BP表示。 该疫苗株属于系统发育系统的基因型I亚型。 疫苗染色剂对鸡呼吸器和消化器官具有亲和力。 用于预防新城疫的疫苗含有疫苗株。 通过饮酒,滴眼或喷雾将疫苗接种给鸡。 该疫苗以亚单位疫苗,载体疫苗,嵌合疫苗或DNA疫苗制造。 疫苗含有可接受的培养基或赋形剂和佐剂。

    약독화된 닭전염성 기관지염 바이러스 및 이를 포함하는 닭전염성 기관지염 백신
    78.
    发明公开
    약독화된 닭전염성 기관지염 바이러스 및 이를 포함하는 닭전염성 기관지염 백신 有权
    用于AVIAN感染性BRONCHITIS病毒和疫苗的AVIAN感染性BRONCHITIS包含它们

    公开(公告)号:KR1020100101216A

    公开(公告)日:2010-09-17

    申请号:KR1020090019581

    申请日:2009-03-09

    CPC classification number: C12N7/00 A61K35/76

    Abstract: PURPOSE: An attenuated avian infectious bronchitis virus and a vaccine containing the same for avian infectious bronchitis are provided to prevent avian infectious bronchitis virus. CONSTITUTION: An attenuated avian infectious bronchitis virus strain is made by attenuating toxicity to chicken by sub-culturing virus stain and S1 protein is mutated. The mutant S1 protein is mutated from serine to tyrosine. The mutant S1 protein has an amino acid sequence of sequence number 4. The attenuated avian infectious bronchitis virus strain is IBV AVR1/08 strain(deposit number: KCTC 11467BP). A vaccine for preventing avian infectious bronchitis for preventing respiratory avian infectious bronchitis contains the attenuated avian infectious bronchitis virus strain. The vaccine additionally contains an adjuvant.

    Abstract translation: 目的:提供减毒的禽传染性支气管炎病毒和含有禽流感感染性支气管炎的疫苗,以预防禽传染性支气管炎病毒。 构成:减毒的禽传染性支气管炎病毒株是通过亚培养病毒染色来减毒对鸡的毒性,S1蛋白被突变。 突变体S1蛋白从丝氨酸突变为酪氨酸。 突变体S1蛋白具有序列号4的氨基酸序列。减毒的禽传染性支气管炎病毒株是IBV AVR1 / 08菌株(保藏号:KCTC 11467BP)。 用于预防禽传染性支气管炎以预防呼吸道禽传染性支气管炎的疫苗含有减毒的禽传染性支气管炎病毒株。 疫苗另外含有佐剂。

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