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公开(公告)号：KR1020100102756A
公开(公告)日：2010-09-27
申请号：KR1020090020957
申请日：2009-03-12
Applicant: 원광대학교산학협력단
CPC classification number: Y02A50/473
Abstract: PURPOSE: A composition containing Torilidis Fructus extract for enhancing immunity is provided to enhance TLR-2 and TLR-4 activity in immunocytes. CONSTITUTION: A pharmaceutical composition for enhancing immunity contains Torilidis Fructus extract as an active ingredient. The Torilidis Fructus extract is isolated using water, low alcohol of C1-C4 or mixture solvent thereof. The Torilidis Fructus extract is contained in the composition in 0.1-50 weight%. A functional health food for enhancing immunity contains Torilidis Fructus extract as an active ingredient. The functional health food is used in the form of powder, granule, tablet, capsule or beverage. A feed additive for enhancing immunity of animal contains the Torilidis Fructus extract as an active ingredient.
Abstract translation: 目的：提供含有用于增强免疫力的Torilidis Fructus提取物的组合物，以增强免疫细胞中的TLR-2和TLR-4活性。 构成：用于增强免疫力的药物组合物含有Torilidis Fructus提取物作为活性成分。 使用水，C1-C4的低级醇或其混合溶剂分离Torilidis Fructus提取物。 组合物中含有枸杞子提取物为0.1-50重量％。 用于增强免疫力的功能性保健食品含有Torilidis Fructus提取物作为活性成分。 功能保健食品以粉末，颗粒，片剂，胶囊或饮料的形式使用。 用于增强动物免疫力的饲料添加剂含有Torilidis Fructus提取物作为活性成分。
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公开(公告)号：KR1020100090860A
公开(公告)日：2010-08-18
申请号：KR1020090010066
申请日：2009-02-09
Applicant: 원광대학교산학협력단
IPC: A61K36/488 , A61P37/00
CPC classification number: A61K36/488
Abstract: PURPOSE: A composition containing Puerariae Radix extract for enhancing immunity is provided to prevent and suppress immune deficiency and to use a s food, medicinal product, and feed additive. CONSTITUTION: A pharmaceutical composition for enhancing immunity contains 0.1-50 weight% of Puerariae Radix extract as an active ingredient. The extract is isolated using water, low alcohol of 1-4 carbon atoms, or mixture solvent. A health food for enhancing immunity contains Puerariae Radix extract as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, or beverage. An animal feed additive for enhancing immunity contains the Puerariae Radix extract as an active ingredient.
Abstract translation: 目的：提供含有葛根提取物用于增强免疫力的组合物，以预防和抑制免疫缺陷，并使用食品，药用产品和饲料添加剂。 构成：用于增强免疫力的药物组合物含有0.1-50重量％的葛根提取物作为活性成分。 使用水，1-4碳原子的低级醇或混合溶剂分离提取物。 用于增强免疫力的保健食品含有葛根提取物作为活性成分。 保健食品以粉末，颗粒，片剂，胶囊或饮料的形式使用。 用于增强免疫力的动物饲料添加剂含有葛根提取物作为活性成分。
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73.发明公开항균 및 항바이러스 활성을 갖는 오배자 추출물 또는이로부터 분리된 화합물을 유효성분으로 함유하는 수의학적조성물 失效包含GALLA RHOIS或其分离的化合物的兽药组合物显示出抗生素和抗病毒活性
公开(公告)号：KR1020090072526A
公开(公告)日：2009-07-02
申请号：KR1020070140663
申请日：2007-12-28
Applicant: 삼광생명과학 주식회사 , 원광대학교산학협력단
IPC: A61K31/19 , A61K31/192 , A61K36/22 , A61P31/04
Abstract: A veterinary composition containing a Galla rhois extract or compound isolated from the extract is provided to prevent and treat respiratory and digestive diseases of pig. A veterinary composition for preventing and treating respiratory and digestive diseases of pig comprises a Galla rhois extract or compound isolated from the extract as an active ingredient. The extract is isolated using water, low alcohol of C1-C4 or their solvent. The compound is a compound selected from gallic acid, mixture of p-digallic acid and m-digallic acid, penta-O-galloyl glucose, ethyl gallate or mixture of ethyl p-digallate and ethyl m-digallate. The compound is denoted by the chemical formula 1, 2, 3, 4, or 5.
Abstract translation: 提供含有从提取物中分离出的加拉罗非鱼提取物或化合物的兽用组合物，以预防和治疗猪的呼吸和消化疾病。 用于预防和治疗猪的呼吸和消化疾病的兽用组合物包括从提取物中分离的加拉罗非鱼提取物或化合物作为活性成分。 使用水，C1-C4的低级醇或其溶剂分离提取物。 该化合物是选自没食子酸，对双氢
萮酸和间二硝酸的混合物，五-O-乙酰基葡萄糖，没食子酸乙酯或对二乙酸乙酯和间二乙酸乙酯的混合物的化合物。 该化合物由化学式1，2，3，4或5表示。-
公开(公告)号：KR1020080047493A
公开(公告)日：2008-05-29
申请号：KR1020060117293
申请日：2006-11-25
Applicant: 원광대학교산학협력단
IPC: A61K36/605 , A61P37/04
CPC classification number: A61K36/605 , A23V2200/324 , A61K2236/331 , Y10S514/885
Abstract: An extract of Mori Fructus is provided to increase NO secretion and cytokine expression, enhance the bacteria phagocytic effect, increase expression of many co-stimulatory molecules, express TLR-4, increase the expression of TLR-4(toll-like receptor 4) and CD14, and show the immunoglobulin increasing effect and B cells and T cells activity, thereby being used as a pharmaceutical composition and a health functional food for enhancing immunity. A pharmaceutical composition for enhancing immunity comprises an extract of Mori Fructus, which is extracted by using a polar solvent such as water, C1-4 alcohol and a mixture thereof. The composition further comprises a carrier, an excipient or a diluent. A health functional food for preventing and improving immunodepression comprises the extract of Mori Fructus.
Abstract translation: 提供山楂提取物以增加NO分泌和细胞因子表达，增强细菌吞噬作用，增加许多共刺激分子的表达，表达TLR-4，增加TLR-4（toll样受体4）的表达和 CD14，并显示免疫球蛋白增加效应和B细胞和T细胞活性，从而用作药物组合物和用于增强免疫力的健康功能食品。 用于增强免疫力的药物组合物包括通过使用极性溶剂如水，C 1-4醇及其混合物提取的山楂提取物。 组合物还包含载体，赋形剂或稀释剂。 用于预防和改善免疫抑制的健康功能食品包括森林提取物。
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公开(公告)号：KR1020070096688A
公开(公告)日：2007-10-02
申请号：KR1020060027617
申请日：2006-03-27
Applicant: 원광대학교산학협력단
IPC: A01N65/08
CPC classification number: A01N65/08 , A01N43/16 , A61K31/366 , A61K31/37 , A61K36/63
Abstract: An antibacterial composition containing the extract of Fraxinus rhynchophylla or compounds isolated therefrom is provided to inhibit growth of zoonoses-causing pathogenic bacteria with reduced toxicity and tolerance. An antibacterial composition for inhibiting growth of zoonoses-causing pathogenic bacteria contains the extract of Fraxinus rhynchophylla which is prepared with water, C1-C4 lower alcohol or a mixed solvent thereof, or compounds isolated from the Fraxinus rhynchophylla extract including esculetin(6,7-dihydroxy coumarin), fraxidin(6,7-dimethoxy-8-hydroxy coumarin), fraxetin(7,8-dihydroxy-6-methoxy coumarin), oleuropein, fraxidin 8-O-beta-D-glucopyranoside and escuside, wherein the zoonoses-causing pathogenic bacteria include Salmonella typhimurium.
Abstract translation: 提供含有弗氏毒素提取物或从其分离的化合物的抗菌组合物，以抑制毒性和耐受性降低的人畜共患病致病菌的生长。 用于抑制人畜共患病致病细菌生长的抗菌组合物含有由水，C1-C4低级醇或其混合溶剂制备的of藜提取物，或从含有七叶树素（6,7- 二羟基香豆素），弗氏毒素（6,7-二甲氧基-8-羟基香豆素），弗曲西汀（7,8-二羟基-6-甲氧基香豆素），橄榄苦蛋白，弗起毒素8-O-β-D-吡喃葡萄糖苷和escuside，其中人畜共患病 - 致病菌包括鼠伤寒沙门氏菌
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Patent Agency Ranking
公开(公告)号：KR102076410B1
公开(公告)日：2020-02-11
申请号：KR1020180061977
申请日：2018-05-30
Applicant: 원광대학교산학협력단
IPC: A61K36/704 , A23L33/105 , A23K10/30 , A61P13/12
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公开(公告)号：KR101642435B1
公开(公告)日：2016-07-26
申请号：KR1020140115639
申请日：2014-09-01
Applicant: 경희대학교 산학협력단 , 원광대학교산학협력단
IPC: C07D311/72 , A61K31/355 , A61P25/00 , A61P1/16
Abstract: 본발명은진피로부터메톡시토코페롤을분리하는단계를포함하는메톡시토코페롤의제조방법, 상기방법에의해제조되는메톡시토코페롤또는이의약학적으로허용가능한염, 및이를유효성분으로포함하는신경세포또는간세포보호용조성물에관한것이다. 상기제조방법을통해제조된메톡시토코페롤은신경세포및 간세포보호효과가현저하므로, 뇌질환및 간질환의치료제로서사용될수 있다.
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公开(公告)号：KR1020160039880A
公开(公告)日：2016-04-12
申请号：KR1020140133155
申请日：2014-10-02
Applicant: 원광대학교산학협력단
IPC: A61K31/343 , A61K9/00 , A23L1/30
CPC classification number: A61K31/343 , A23L33/10 , A23V2002/00 , A23V2200/00 , A61K9/0019
Abstract: 본발명은급성췌장염의예방, 개선또는치료를위한조성물을제공하기위한것으로서, 더욱상세하게는설퍼레틴을유효성분으로함유하는급성췌장염의예방과치료를위한조성물에관한것이다. 본발명에따른조성물은, 급성췌장염으로인한췌장및 폐조직의손상, 호중구침윤, 아밀라아제및 리파아제분비를억제하고, 췌장중량/체중비율을감소시키며, 면역및 염증조절사이토카인인 IL-10을활성화함으로써급성췌장염을예방, 개선또는치료하는효능을보유하고있다.
Abstract translation: 本发明涉及用于预防，减轻或治疗急性胰腺炎的组合物，更具体地，涉及用于预防和治疗急性胰腺炎的组合物，其包含硫化锡作为活性成分。 根据本发明的组合物抑制胰腺和肺组织的损伤，嗜中性白细胞的浸润以及由急性胰腺炎引起的淀粉酶和脂肪酶的分泌，降低胰腺质量/重量的比例，并且具有预防，缓解或 通过激活IL-10来治疗急性胰腺炎，IL-10是用于控制免疫和炎症的细胞因子。
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公开(公告)号：KR1020160027602A
公开(公告)日：2016-03-10
申请号：KR1020140115639
申请日：2014-09-01
Applicant: 경희대학교 산학협력단 , 원광대학교산학협력단
IPC: C07D311/72 , A61K31/355 , A61P25/00 , A61P1/16
Abstract: 본발명은진피로부터메톡시토코페롤을분리하는단계를포함하는메톡시토코페롤의제조방법, 상기방법에의해제조되는메톡시토코페롤또는이의약학적으로허용가능한염, 및이를유효성분으로포함하는신경세포또는간세포보호용조성물에관한것이다. 상기제조방법을통해제조된메톡시토코페롤은신경세포및 간세포보호효과가현저하므로, 뇌질환및 간질환의치료제로서사용될수 있다.
Abstract translation: 本发明涉及一种甲氧基生育酚的制备方法，其包括通过该方法制备的甲氧基生育酚从Citrus unshiu的皮肤分离成甲氧基生育酚或其药学上可接受的盐，以及用于保护神经元或肝细胞的组合物， 包括甲氧基生育酚或其盐作为活性成分。 通过生产方法生产的甲氧基生育酚具有保护神经元和肝细胞的显着效果，因此被用作脑疾病和肝脏疾病的治疗剂。
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公开(公告)号：KR101470613B1
公开(公告)日：2014-12-10
申请号：KR1020120152544
申请日：2012-12-24
Applicant: 원광대학교산학협력단
IPC: A61K31/045 , A61K31/05 , A61P29/00
Abstract: 본발명은라티폴린(latifolin)을유효성분으로포함하는염증성질환의예방또는치료용조성물에관한것이다. 본발명에따른라티폴린은대식세포에서헴 옥시제나아제-1(HO-1) 효소의발현및 활성증가를통한염증반응억제효과가우수하여, 염증성질환의예방또는치료에유용하게이용될수 있다.
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