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公开(公告)号：KR100757220B1
公开(公告)日：2007-09-10
申请号：KR1020060027616
申请日：2006-03-27
Applicant: 원광대학교산학협력단
IPC: A61K36/185 , A61P37/00
Abstract: A composition for enhancing immune activity comprising the extract of Salicis radicis cortex is provided to increase production of NO2 which inhibit growth of cancer cells, expression of cytokine related to T-cell and expression of CD14 without toxicity to human. A composition for enhancing immune activity comprises 0.1-50 wt.% of the extract of Salicis radicis cortex which is prepared by extracting with a polar solvent selected from water, C1-C4 lower alcohol or a mixed solvent thereof, wherein the daily dosage of Salicis radicis cortex extract is 0.0001-100 mg/kg, preferably 0.001-10 mg/kg and the composition is a pharmaceutical or health food composition having a formulation selected from tablet, capsule, pill and solution. The food or drink for enhancing immune activity comprises 0.01-50 wt.% of the health food composition.
Abstract translation: 提供了一种用于增强免疫活性的组合物，其包含提取水杨酸皮质，以增加抑制癌细胞生长的NO2的产生，与T细胞相关的细胞因子的表达和CD14的表达，而对人没有毒性。 用于增强免疫活性的组合物包含通过用选自水，C 1 -C 4低级醇或其混合溶剂的极性溶剂萃取而制备的百里香提取物的0.1-50重量％，其中Salicis的日剂量 根皮质提取物为0.0001-100mg / kg，优选为0.001-10mg / kg，组合物为具有选自片剂，胶囊，丸剂和溶液的制剂的药物或保健食品组合物。 用于增强免疫活性的食物或饮料包含保健食品组合物的0.01-50重量％。
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Patent Agency Ranking
公开(公告)号：KR1020130124724A
公开(公告)日：2013-11-15
申请号：KR1020120048062
申请日：2012-05-07
Applicant: 원광대학교산학협력단
Abstract: The present invention relates to a composition containing an Ixeris dentata extract as an active ingredient for anti-aging. The Ixeris dentata extract enhances generation of ceramide in cells. Ceramide has a double chain lamellar structure, maintains skin elasticity by inducing a bond between skin surface and keratinocytes, and suppresses skin aging with skin moisturizing effect, thereby suppressing or alleviating skin aging and preventing or treating atopic dermatitis. Accordingly, the Ixeris dentata extract which enhances generation of ceramide in a body can be used as an active ingredient of a composition for treating, alleviating, or preventing atopy and as an active ingredient of a cosmetic composition for skin moisturization. [Reference numerals] (AA) Ixeris dentata extract (쨉g/mL)
Abstract translation: 本发明涉及含有益母草提取物作为抗衰老活性成分的组合物。 Ixeris牙齿提取物增强细胞中神经酰胺的产生。 神经酰胺具有双链层状结构，通过诱导皮肤表面和角质形成细胞之间的结合来保持皮肤弹性，并通过皮肤保湿作用抑制皮肤老化，从而抑制或缓解皮肤老化和预防或治疗特应性皮炎。 因此，可以使用增强体内神经酰胺生成的益母草提取物作为用于治疗，缓解或预防用于皮肤保湿的化妆品组合物的特应性和作为活性成分的组合物的活性成分。 （参考数字）（AA）十字齿提取物（μg/ mL）
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公开(公告)号：KR1020070096688A
公开(公告)日：2007-10-02
申请号：KR1020060027617
申请日：2006-03-27
Applicant: 원광대학교산학협력단
IPC: A01N65/08
CPC classification number: A01N65/08 , A01N43/16 , A61K31/366 , A61K31/37 , A61K36/63
Abstract: An antibacterial composition containing the extract of Fraxinus rhynchophylla or compounds isolated therefrom is provided to inhibit growth of zoonoses-causing pathogenic bacteria with reduced toxicity and tolerance. An antibacterial composition for inhibiting growth of zoonoses-causing pathogenic bacteria contains the extract of Fraxinus rhynchophylla which is prepared with water, C1-C4 lower alcohol or a mixed solvent thereof, or compounds isolated from the Fraxinus rhynchophylla extract including esculetin(6,7-dihydroxy coumarin), fraxidin(6,7-dimethoxy-8-hydroxy coumarin), fraxetin(7,8-dihydroxy-6-methoxy coumarin), oleuropein, fraxidin 8-O-beta-D-glucopyranoside and escuside, wherein the zoonoses-causing pathogenic bacteria include Salmonella typhimurium.
Abstract translation: 提供含有弗氏毒素提取物或从其分离的化合物的抗菌组合物，以抑制毒性和耐受性降低的人畜共患病致病菌的生长。 用于抑制人畜共患病致病细菌生长的抗菌组合物含有由水，C1-C4低级醇或其混合溶剂制备的of藜提取物，或从含有七叶树素（6,7- 二羟基香豆素），弗氏毒素（6,7-二甲氧基-8-羟基香豆素），弗曲西汀（7,8-二羟基-6-甲氧基香豆素），橄榄苦蛋白，弗起毒素8-O-β-D-吡喃葡萄糖苷和escuside，其中人畜共患病 - 致病菌包括鼠伤寒沙门氏菌
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公开(公告)号：KR100757219B1
公开(公告)日：2007-09-10
申请号：KR1020060027615
申请日：2006-03-27
Applicant: 원광대학교산학협력단
CPC classification number: Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/481 , Y02A50/483 , A61K36/65 , Y10S514/885
Abstract: An antibacterial composition containing the extract of Moutan Radicis Cortex or the compounds isolated therefrom is provided to inhibit growth of zoonosis-occurring bacteria with reduced toxicity and tolerance. A composition for inhibiting growth of zoonosis-occurring bacteria contains the extract of Moutan Radicis Cortex or the compounds isolated therefrom including mudanpioside-H or galloyl-oxypaeoniflorin as an effective ingredient, wherein the zoonosis-occurring bacteria include Shigella dysenteriae, Shigella flexneri, Salmonella typhi, Salmonella paratyphi, Salmonella gallinarum, Salmonella typhimurium, Salmonella enteritidis, Vibrio cholerae, Escherichia coli and methicillin-resistant S. aureus(MRSA).
Abstract translation: 提供含有Moutan Radicis Cortex的提取物或从其分离的化合物的抗菌组合物，以抑制毒性和耐受性降低的人畜共患病细菌的生长。 用于抑制人畜共患病发生细菌生长的组合物含有Moutan Radicis Cortex的提取物或其分离的化合物，包括mudanpioside-H或galloyl-oxypaeoniflorin作为有效成分，其中所述人畜共患病发生的细菌包括痢疾志贺氏菌，志贺氏菌志贺氏菌，伤寒沙门氏菌 ，副伤寒沙门氏菌（Salmonella paratyphi），沙门氏菌（Salmonella gallinarum），鼠伤寒沙门氏菌（Salmonella typhimurium），肠炎沙门氏菌（Salmonella enteritidis），霍乱弧菌（Escherichia coli）和耐甲氧西林金黄色葡萄球菌（MRSA）。
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公开(公告)号：KR100777834B1
公开(公告)日：2007-11-28
申请号：KR1020060027617
申请日：2006-03-27
Applicant: 원광대학교산학협력단
IPC: A01N65/08
Abstract: 본 발명은 항균 활성을 갖는 조성물에 관한 것으로서, 상세하게는 물푸레나무(
Fraxinus
rhynchophylla )의 줄기 껍질인 진피 (Fraxini Cortex)의 추출물 및 이로부터 분리된 화합물들은 인수 공통 전염병 균주에 대한 억제 활성을 나타내므로 항균조성물로 이용될 수 있다.
물푸레나무, 진피, 인수공통 전염병, 크로마토그래피, 항균제-
公开(公告)号：KR100734514B1
公开(公告)日：2007-07-03
申请号：KR1020060026961
申请日：2006-03-24
Applicant: 원광대학교산학협력단
Abstract: A composition for the treatment and protection of immune disease comprising the extract of Anethi fructus is provided to increase NO2 production causing inhibition of cancer cells, cytokine expression, CD14 expression causing T-cell production and spleen cell growth, and inhibit growth of bacteria. The composition for the treatment and protection of immune disease comprises 0.1-50 wt.% of the extract of Anethi fructus which is prepared by extracting Anethi fructus with a polar solvent of water or C1-C4 lower alcohol. The daily dosage of the Anethi fructus extract is 0.0001 to 100 mg/kg and the composition is a pharmaceutical or health food composition. The health food composition is formulated as powder, granule, tablet, capsule, pill, solution or drink.
Abstract translation: 提供了用于治疗和保护免疫疾病的组合物，其包含提取物的Anethi fructus以提高NO2产生，从而导致癌细胞的抑制，细胞因子表达，导致T细胞产生和脾细胞生长的CD14表达，并抑制细菌的生长。 用于治疗和保护免疫疾病的组合物含有0.1-50wt。％的Anethi fructus提取物，其通过用极性溶剂或C1-C4低级醇提取Anethi fructus而制备。 安息香提取物的日剂量为0.0001至100mg / kg，组合物为药物或保健食品组合物。 保健食品组合物配制成粉末，颗粒，片剂，胶囊，丸剂，溶液或饮料。
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