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公开(公告)号:NO170570C
公开(公告)日:1992-11-04
申请号:NO871513
申请日:1987-04-10
Applicant: BASF AG
Inventor: GOERTZ HANS-HELMUT , KLIMESCH ROGER GUENTHER , LAEMMERHIRT KLAUS , LANG SIEGFRIED , SANNER AXEL , SPENGLER REINHARD
Abstract: Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50 DEG to 180 DEG C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.
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公开(公告)号:ES2022188B3
公开(公告)日:1991-12-01
申请号:ES87104731
申请日:1987-03-31
Applicant: BASF AG
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公开(公告)号:HUT55218A
公开(公告)日:1991-05-28
申请号:HU162387
申请日:1987-04-10
Applicant: BASF AG
Inventor: BLECKMANN GERHARD , GOERTZ HANS-HELMUT , KLIMESCH ROGER GUENTHER , FARWERCK KARL-PETER , SCHLEMMER LOTHAR
IPC: A61H39/00 , A61J3/10 , A61K9/20 , A61K9/22 , A61K9/26 , B29B9/06 , B30B11/16 , B30B11/24 , A61J3/06
Abstract: Extrudable pharmaceutical mixtures are tableted by a continuous method in which the mixture is extruded and the still deformable extrudate is pressed between two rollers which are driven in opposite directions and possess depressions opposite one another in the roller shell, the form of these depressions determining the tablet shape.
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公开(公告)号:PT84660B
公开(公告)日:1989-11-30
申请号:PT8466087
申请日:1987-04-10
Applicant: BASF AG
Inventor: GOERTZ HANS-HELMUT , KLIMESCH ROGER GUENTHER , BLECKMANN GERHARD , FARWERCK KARL-PETER , SCHLEMMER LOTHAR
Abstract: Extrudable pharmaceutical mixtures are tableted by a continuous method in which the mixture is extruded and the still deformable extrudate is pressed between two rollers which are driven in opposite directions and possess depressions opposite one another in the roller shell, the form of these depressions determining the tablet shape.
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公开(公告)号:HUT43958A
公开(公告)日:1988-01-28
申请号:HU161787
申请日:1987-04-10
Applicant: BASF AG
Inventor: GOERTZ HANS-HELMUT , KLIMESCH ROGER G , LAEMMERHIRT KLAUS , LANG SIEGFRIED , SANNER AXEL , SPENGLER REINHARD
Abstract: Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50 DEG to 180 DEG C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.
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公开(公告)号:PT84661A
公开(公告)日:1987-05-01
申请号:PT8466187
申请日:1987-04-10
Applicant: BASF AG
Inventor: GOERTZ HANS-HELMUT , GUENTHER ROGER , LAEMMERHIRT KLAUS , LANG SIEGFRIED , SANNER AXEL , SPENGLER REINHARD
Abstract: Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50 DEG to 180 DEG C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.
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公开(公告)号:DE59703469D1
公开(公告)日:2001-06-07
申请号:DE59703469
申请日:1997-02-19
Applicant: BASF AG
Inventor: LYNCH JOHN , FISCHER DAVID , GOERTZ HANS-HELMUT , SCHWEIER GUENTHER
IPC: C08F2/34 , C08F4/619 , C08F4/6192 , C08F4/646 , C08F4/68 , C08F10/00 , C08F110/02
Abstract: Polymerizable alkanes are prepared by gas-phase polymerization in the presence of catalyst systems by a process in which the catalyst systems used are supported castalyst systems.
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公开(公告)号:DE59703436D1
公开(公告)日:2001-05-31
申请号:DE59703436
申请日:1997-02-19
Applicant: BASF AG
Inventor: LYNCH JOHN , FISCHER DAVID , GOERTZ HANS-HELMUT , SCHWEIER GUENTHER
IPC: C08F4/12 , C08F4/44 , C08F4/60 , C08F4/619 , C08F4/6192 , C08F4/646 , C08F4/68 , C08F10/00 , C08F110/02
Abstract: Supported catalyst systems are obtainable byA) reaction of an inorganic carrier with a metal compound of the general formula I whereM1 is an alkali metal, an alkaline earth metal or a metal of main group III or IV of the Periodic Table,R1 is hydrogen, Ch1-C10-alkyl, C6-C15-aryl, alkylaryl or arylalkyl each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,R2 to R4 are each hydrogen, halogen, C1-C10-alkyl, C6-C15-aryl, alkylaryl, arylalkyl, alkoxy or dialkylamino each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,r is an integer from 1 to 4 ands, t and u are integers from 0 to 3 the sum r+s+t+u corresponding to the valency of M1,B) reaction of the material obtained according to A) with a metallocene complex in its metal dihalide form and a compound forming metallocenium ions andC) subsequent reaction with a metal compound of the general formula II whereM2 is an alkali metal, an alkaline earth metal or a metal of main group III of the Periodic Table,R5 is hydrogen, C1-C10-alkyl, C6-C15-aryl, alkylaryl or arylalkyl each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,R6 and R7 are hydrogen, halogen, C1-C10-alkyl, C6-C15-aryl, alkylaryl, arylalkyl or alkoxy each having 1 to 10 carbon atoms in the alkyl radical and 6 to 20 carbon atoms in the aryl radical,o is an integer from 1 to 3 andp and q are integers from 0 to 2 the sum o+p+q corresponding to the valency of M2.
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公开(公告)号:NO309193B1
公开(公告)日:2000-12-27
申请号:NO962696
申请日:1996-06-26
Applicant: BASF AG
Inventor: LUX MARTIN , SAIVE ROLAND , LANGHAUSER FRANZ , MICKLITZ WOLFGANG , GOERTZ HANS-HELMUT , LILGE DIETER
IPC: C08F2/06 , C08F2/14 , C08F4/606 , C08F4/639 , C08F4/6392 , C08F4/64 , C08F4/642 , C08F4/646 , C08F4/6592 , C08F10/00 , C08F10/02 , C08F110/02 , C08F210/16
Abstract: PCT No. PCT/EP94/04125 Sec. 371 Date Jun. 26, 1996 Sec. 102(e) Date Jun. 26, 1996 PCT Filed Dec. 13, 1994 PCT Pub. No. WO95/18160 PCT Pub. Date Jul. 6, 1995Homopolymers of ethylene or copolymers of ethylene with other olefins or mixtures thereof are prepared by suspension polymerization in the presence of catalyst systems by a process in which the catalyst systems used are those which contain, as active components, A) a finely divided carrier treated with trialkylaluminum, B) a metallocene complex, C) an open-chain or cyclic alumoxane compound and D) an alkali metal alkyl or alkaline earth metal alkyl or a mixture thereof.
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公开(公告)号:DE59404553D1
公开(公告)日:1997-12-11
申请号:DE59404553
申请日:1994-12-13
Applicant: BASF AG
Inventor: LUX MARTIN , SAIVE ROLAND , LANGHAUSER FRANZ , MICKLITZ WOLFGANG , GOERTZ HANS-HELMUT , LILGE DIETER
IPC: C08F2/06 , C08F2/14 , C08F4/606 , C08F4/639 , C08F4/6392 , C08F4/64 , C08F4/642 , C08F4/646 , C08F4/6592 , C08F10/00 , C08F10/02 , C08F110/02 , C08F210/16
Abstract: PCT No. PCT/EP94/04125 Sec. 371 Date Jun. 26, 1996 Sec. 102(e) Date Jun. 26, 1996 PCT Filed Dec. 13, 1994 PCT Pub. No. WO95/18160 PCT Pub. Date Jul. 6, 1995Homopolymers of ethylene or copolymers of ethylene with other olefins or mixtures thereof are prepared by suspension polymerization in the presence of catalyst systems by a process in which the catalyst systems used are those which contain, as active components, A) a finely divided carrier treated with trialkylaluminum, B) a metallocene complex, C) an open-chain or cyclic alumoxane compound and D) an alkali metal alkyl or alkaline earth metal alkyl or a mixture thereof.
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