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    ORAL CARE COMPOSITION COMPRISING AN AMADORI COMPOUND
    71.
    发明申请
    ORAL CARE COMPOSITION COMPRISING AN AMADORI COMPOUND 审中-公开
    口服护理组合物包含阿马可乐化合物

    公开(公告)号：WO2014098793A1

    公开(公告)日：2014-06-26

    申请号：PCT/US2012/070101

    申请日：2012-12-17

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： HAO, Zhigang ,  YANG, Ying ,  LIU, Zhiqiang ,  HU, Katherine ,  XU, Guofeng ,  VINCENTI, Paul Joseph

    IPC: A61K8/60 ,  A61Q11/00

    CPC classification number: A61K8/60 ,  A61K2800/92 ,  A61Q11/00

    Abstract: The present invention relates to oral care compositions and methods of inhibiting microbial biofilm formation and/or degrading a microbial biofilm. Disclosed herein are oral care compositions comprising an Amadori compound having a glucose moiety and an amino acid moiety. The Amadori compound has use for inhibiting oral microbial biofilm formation and/or degrading an oral microbial biofilm in the oral cavity of a mammalian subject.

    Abstract translation: 本发明涉及口腔护理组合物和抑制微生物生物膜形成和/或降解微生物生物膜的方法。 本文公开了包含具有葡萄糖部分和氨基酸部分的阿马多里化合物的口腔护理组合物。 阿马多利化合物可用于抑制口腔微生物生物膜形成和/或降解哺乳动物受试者口腔中的口腔微生物生物膜。

    DESENSITIZING DENTIFRICE EXHIBITING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE
    73.
    发明申请
    DESENSITIZING DENTIFRICE EXHIBITING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE 审中-公开
    脱皮剂展示牙科组织抗菌药物摄取

    公开(公告)号：WO2010114538A1

    公开(公告)日：2010-10-07

    申请号：PCT/US2009/039194

    申请日：2009-04-01

    Applicant: COLGATE-PALMOLIVE COMPANY ,  XU, Guofeng ,  SUBRAMANYAM, Ravi

    Inventor： XU, Guofeng ,  SUBRAMANYAM, Ravi

    IPC: A61K8/19 ,  A61K8/44 ,  A61K8/46 ,  A61Q11/00 ,  A61K8/34

    CPC classification number: A61Q11/00 ,  A61K8/19 ,  A61K8/20 ,  A61K8/347 ,  A61K8/463 ,  A61K8/466

    Abstract: An oral composition exhibiting increased uptake by dental tissue of antibacterial compounds contained therein and eliminating or substantially reducing the discomfort and pain associated with dentinal hypersensitivity. The composition includes an orally acceptable vehicle for such composition, an effective therapeutic amount of an antibacterial compound, a mixture of anionic surfactant and amphoteric surfactant, the mixture having 0.1 wt. % to 2.0 wt. % anionic surfactant and 0.8 wt. % to 2.0 wt. % amphoteric surfactant, and a potassium ion releasable compound.

    Abstract translation: 一种口服组合物，其表现出牙齿组织对其中所含的抗菌化合物的吸收增加，并消除或显着降低与牙质过敏有关的不适和疼痛。 该组合物包括用于这种组合物的口服可接受的载体，有效治疗量的抗菌化合物，阴离子表面活性剂和两性表面活性剂的混合物，该混合物具有0.1wt。 ％〜2.0重量％ ％阴离子表面活性剂和0.8wt。 ％〜2.0重量％ ％两性表面活性剂和一种钾离子可释放的化合物。

    MULTILAYER TOOTH WHITENING STRIPS
    75.
    发明申请
    MULTILAYER TOOTH WHITENING STRIPS 审中-公开
    多层牙膏白色条纹

    公开(公告)号：WO2005110344A1

    公开(公告)日：2005-11-24

    申请号：PCT/US2005/016165

    申请日：2005-05-10

    Applicant: COLGATE-PALMOLIVE COMPANY ,  HASSAN, Mahmoud ,  XU, Guofeng ,  VISCIO, David ,  GAFFAR, Abdul

    Inventor： HASSAN, Mahmoud ,  XU, Guofeng ,  VISCIO, David ,  GAFFAR, Abdul

    IPC: A61K7/16

    CPC classification number: A61K8/0208 ,  A61C19/066 ,  A61K8/22 ,  A61K8/731 ,  A61K8/8176 ,  A61K8/86 ,  A61Q11/00

    Abstract: Tooth-whitening films comprising a hydratable polymer and a whitening agent are disclosed in which the films have a hydrophobic coating on one surface and a tooth-adherent coating on the opposing surface. Flavorings can also be included in the hydratable polymer portion of the film or in either the hydrophobic coating or the tooth-adherent coating. Tooth-whitening methods that use the films are also disclosed. The hydratable polymer preferably is a polyethylene oxide.

    Abstract translation: 公开了包含可水合聚合物和增白剂的牙齿增白膜，其中所述膜在一个表面上具有疏水性涂层，并且在相对表面上具有牙齿粘附涂层。 调味剂也可以包括在膜的可水合的聚合物部分中或在疏水性涂层或牙粘附涂层中。 还公开了使用这些膜的牙齿美白方法。 可水合的聚合物优选为聚环氧乙烷。

    STRIP FOR WHITENING TOOTH SURFACES
    77.
    发明申请
    STRIP FOR WHITENING TOOTH SURFACES 审中-公开
    用于白色表面的条纹

    公开(公告)号：WO2003072076A1

    公开(公告)日：2003-09-04

    申请号：PCT/US2003/005320

    申请日：2003-02-20

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： XU, Guofeng ,  VISCIO, David, B.

    IPC: A61K7/16

    CPC classification number: A61K8/0208 ,  A61K6/0023 ,  A61K8/19 ,  A61K8/22 ,  A61K8/86 ,  A61K2800/31 ,  A61Q11/00 ,  C08L71/02

    Abstract: A thin, flexible film which when applied to stained teeth is hydrated by saliva and is effective in such form to whiten teeth, the film comprising an anhydrous water hydratable ethylene oxide polymer matrix containing a solid peroxide whitening agent whereby upon application to stained tooth surfaces, the peroxide whitening agent is solublilized by saliva present in the oral cavity into active whitening activity when the film is positioned and placed on the teeth.

    Abstract translation: 一种薄而柔软的膜，当应用于染色的牙齿时，通过唾液进行水合，并且以这种形式有效地使牙齿变白，该膜包含含有固体过氧化物增白剂的无水可水合环氧乙烷聚合物基质，由此当应用于染色的牙齿表面时， 当将膜定位并放置在牙齿上时，过氧化物增白剂可通过口腔中的唾液溶解而成活性增白活性。

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