公开(公告)号：AU2015280604B2

公开(公告)日：2017-04-20

申请号：AU2015280604

申请日：2015-05-26

Applicant: GERBER MARTIN T ,  HOBOT CHRISTOPHER M ,  MEDTRONIC INC ,  PUDIL BRYANT J

Inventor： PUDIL BRYANT J ,  GERBER MARTIN T ,  HOBOT CHRISTOPHER M

IPC: B01J20/34 ,  A61M1/16 ,  B01J19/18 ,  B01J19/24 ,  B01J20/02 ,  B01J39/08

Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.

公开(公告)号：AU2015203047A1

公开(公告)日：2015-07-16

申请号：AU2015203047

申请日：2015-06-09

Applicant: MEDTRONIC INC ,  WARSAW ORTHOPEDIC INC

Inventor： ZANELLA JOHN MYERS ,  KING VANJA MARGARETA ,  HOBOT CHRISTOPHER M ,  HILDEBRAND KEITH R

IPC: A61K31/415 ,  A61K9/20 ,  A61K31/56 ,  A61K31/573 ,  A61P29/00

Abstract: Effective methods for treating pain are provided. Through the injection of liquid formulation comprising an active ingredient followed by the administration of drug depot comprising an active ingredient at or near a target site, one can effectively treat pain. This methodology is particularly effective to treat acute radicular pain.

公开(公告)号：BRPI0904957A2

公开(公告)日：2015-06-30

申请号：BRPI0904957

申请日：2009-04-17

Applicant: WARSAW ORTHOPEDIC INC ,  MEDTRONIC INC

Inventor： KING VANJA MARGARETA ,  HOBOT CHRISTOPHER M ,  BIGGS DANIELLE ,  SHAW KATARA ,  WOHABREBBI AMIRA ,  MCKAY WILLIAM F ,  MCDONALD PHILLIP EDWARD

IPC: A61K31/4458 ,  A61K9/20 ,  A61K47/34 ,  A61P29/00

公开(公告)号：BRPI0904956A2

公开(公告)日：2015-06-30

申请号：BRPI0904956

申请日：2009-04-17

Applicant: WARSAW ORTHOPEDIC INC ,  MEDTRONIC INC

Inventor： KING VANJA MARGARETA ,  HOBOT CHRISTOPHER M ,  MCKAY WILLIAM F ,  WOHABREBBI AMIRA ,  MCDONALD PHILLIP EDWARD ,  CARTER TROY

IPC: A61K9/00 ,  A61K9/20 ,  A61K31/4162 ,  A61K47/34

公开(公告)号：AU2009236115B2

公开(公告)日：2015-05-21

申请号：AU2009236115

申请日：2009-04-17

Applicant: MEDTRONIC INC ,  WARSAW ORTHOPEDIC INC

Inventor： REMSEN KATHY L ,  MCDONALD PHILLIP EDWARD ,  ZANELLA JOHN MYERS ,  HOBOT CHRISTOPHER M ,  MCKAY WILLIAM F ,  SHAW KATARA ,  KING VANJA MARGARETA ,  BIGGS DANIELLE

IPC: A61K9/00 ,  A61K9/20 ,  A61K31/4162 ,  A61K47/34

Abstract: Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relieve pain caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discogenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

公开(公告)号：AU2009322637A1

公开(公告)日：2011-06-30

申请号：AU2009322637

申请日：2009-11-30

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E ,  HOBOT CHRISTOPHER M ,  EDWARD MCDONALD PHILLIP ,  LUO LIAN L ,  JOHN KRAMER

IPC: A61K9/22 ,  A61K47/34

Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.

公开(公告)号：CA2745414A1

公开(公告)日：2010-06-10

申请号：CA2745414

申请日：2009-11-30

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E ,  HOBOT CHRISTOPHER M ,  MCDONALD PHILLIP EDWARD ,  LUO LIAN L ,  KRAMER JOHN

IPC: A61K9/22 ,  A61K47/34

Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.

公开(公告)号：CA2700196A1

公开(公告)日：2009-10-22

申请号：CA2700196

申请日：2009-04-17

Applicant: WARSAW ORTHOPEDIC INC ,  MEDTRONIC INC

Inventor： ZANELLA JOHN MYERS ,  KING VANJA MARGARETA ,  HOBOT CHRISTOPHER M ,  HILDEBRAND KEITH R

IPC: A61K31/415 ,  A61K9/20 ,  A61K31/56 ,  A61K31/573 ,  A61P29/00

Abstract: Effective methods for treating pain are provided. Through the injection of liquid formulation comprising an active ingredient followed by the administration of drug depot comprising an active ingredient at or near a target site, one can effectively treat pain. This methodology is particularly effective to treat acute radicular pain.

公开(公告)号：DE60231004D1

公开(公告)日：2009-03-12

申请号：DE60231004

申请日：2002-12-12

Applicant: MEDTRONIC INC

Inventor： HOBOT CHRISTOPHER M ,  SPEAR STANTON C ,  KELLEY JAMES F ,  BAUNSCHWEIG JENNIFER L ,  DANG KIEM ,  GARDESKI KENNETH C

IPC: A61L29/00 ,  A61L29/18 ,  A61L29/02 ,  A61L29/12 ,  A61L31/12 ,  A61L31/18 ,  A61M25/00 ,  A61M25/01 ,  A61M25/088

Abstract: An elongated sheath of a guide catheter includes a fully radiopaque and echogenic distal tip having a length greater than approximately 0.08 inch.

公开(公告)号：DE69838479T2

公开(公告)日：2008-06-19

申请号：DE69838479

申请日：1998-05-08

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL ERIC ,  BONNEMA KELVIN ,  DIDOMENICO EDWARD ,  HOBOT CHRISTOPHER M ,  MILLER DAVID L

IPC: A61L27/00 ,  A61L27/18 ,  A61L27/34 ,  A61L29/06 ,  A61L29/08 ,  A61L31/06 ,  A61L31/10 ,  A61L33/06