公开(公告)号：WO2006104311A1

公开(公告)日：2006-10-05

申请号：PCT/KR2006/000559

申请日：2006-02-17

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE ,  PARK, Sang-Ryoul ,  YANG, In-Chul ,  KIM, Yeong-Ho ,  JANG, Seong-Moon

Inventor： PARK, Sang-Ryoul ,  YANG, In-Chul ,  KIM, Yeong-Ho ,  JANG, Seong-Moon

IPC: B01L3/02

CPC classification number: B01L3/50 ,  B01L2300/0838 ,  B01L2400/0418 ,  C12M35/02

Abstract: The present invention relates to a device for injecting and extracting accurately infinitesimal amount of sample according to a magnitude of volage and a direction of current applied to a device for generating an electroosmotic flow by coupling ultra-micro capillaries for injecting and extracting the sample with an electroosmotic flow generating device in which an electrical circuit is completed through an electroconductive membrane, and a method for manufacturing the same. The device according to the present invention is invented for injecting and extracting accurately infinitesimal amount of sample for the single cell as the object, however, the present invention can be applied to all the other fields in which infinitesimal amount of sample should be accurately treated. As compared with the conventional air pressure type or mechanical pumping method having various problems due to an extreme resistance to the fluid flowed through the ultra-micro capillary, in the electroosmotic flow-type device, a driving force is generated on a surface of inner wall of the capillary so that there is no a resistance in the capillary although the fluid is flowed therein. Also, since a regulation of the driving force is achived by an accurate and simple regulation of the voltage, a flow of infinitesimal amount of fluid can be accurately controlled. In the present invention, the capillary for generating the electroosmotic flow is directly coupled with the capillary for extracting the sample through the electroconductive tube, the electroosmotic flow-type ultra-micro pipet divce in which a dead volume generated at a coupling section is minimized can be conveniently manufactured and employed.

Abstract translation: 本发明涉及一种用于根据挥发的大小和施加到用于产生电渗流的装置的电流的方向精确地注入和提取无限量的样品的装置，其通过耦合超微毛细管用于将样品注入和提取样品 通过导电膜完成电路的电渗流产生装置及其制造方法。 本发明的发明是为了将单个电池作为目的，准确地进行极小量的样品的注入和提取，但是本发明可以应用于其中精确处理无限量的样品的所有其它领域。 与传统的气压式或机械抽吸方法相比，由于对流过超微毛细管的流体具有极高的抵抗力，因此在电渗流型装置中产生驱动力，在内壁的表面上产生驱动力 的毛细管，使得毛细管中没有阻力，尽管流体在其中。 此外，由于通过电压的精确和简单的调节来调节驱动力，因此可以精确地控制流体的极小量。 在本发明中，用于产生电渗流的毛细管与用于通过导电管提取样品的毛细管直接耦合，其中在耦合部分产生的死体积最小化的电渗流型超微移液管分流可以 方便生产和使用。

公开(公告)号：WO2006088311A1

公开(公告)日：2006-08-24

申请号：PCT/KR2006/000525

申请日：2006-02-15

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE ,  SUH, Hosuhng ,  MOON, Hanseb ,  LEE, Wonkyu ,  RYU, Hanyoung ,  KANG, Seonmo

Inventor： SUH, Hosuhng ,  MOON, Hanseb ,  LEE, Wonkyu ,  RYU, Hanyoung ,  KANG, Seonmo

CPC classification number: H01S3/06791 ,  H01S3/08031 ,  H01S3/1062 ,  H01S3/137 ,  H04J14/02

Abstract: Provided is a fiber ring laser capable of obtaining a back up laser light and standard light having a wavelength continuously tuned in a single mode with equal spacing of 12.5GHz, 25GHz, 50GHz or 100GHz recommended by ITU-T Recommendation G. 692 & G. 694.1 in a C-band and an L-band using a fiber tunable etalon filter, an air gap etalon filter and a saturable absorber in an optical fiber laser resonator having a serial ring shape using a C-band optical amplifier and an L-band optical amplifier. The fiber ring laser can generate laser light having a wavelength tuned by more than 70nm, excellent output power flatness and a source spontaneous emission ratio of more than 7OdB in 361 channels with equal spacing of 25GHz by applying a bias voltage to a voltage-operated piezoelectric element of a tunable etalon filter. A single longitudinal mode operation of the fiber ring laser can be obtained by using a saturable absorber serving as a narrow-bandwidth filter.

Abstract translation: 提供了能够获得备用激光的光纤环形激光器和具有以单模模式连续调谐的波长的标准光，其间隔为ITU-T G.692＆G建议书推荐的12.5GHz，25GHz，50GHz或100GHz等间隔。 694.1在使用C波段光放大器和L波段的具有串行环形的光纤激光谐振器中使用光纤可调标准具滤波器，气隙标准具滤波器和可饱和吸收器的C波段和L波段 光放大器。 光纤环形激光器可以产生具有超过70nm的波长的激光，具有优异的输出功率平坦度和源自发发射比大于70dB的激光，其中361个通道具有等于25GHz的间隔，通过对电压操作的压电 可调谐标准具过滤器的元件。 可以通过使用用作窄带滤波器的可饱和吸收器来获得光纤环激光器的单一纵模式操作。

公开(公告)号：WO2006057494A1

公开(公告)日：2006-06-01

申请号：PCT/KR2005/003870

申请日：2005-11-16

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE ,  PARK, Sang-Ryoul ,  YANG, In-Chul ,  KIM, Young-Ho

Inventor： PARK, Sang-Ryoul ,  YANG, In-Chul ,  KIM, Young-Ho

IPC: G01N27/447

CPC classification number: G01N27/44782 ,  B01L9/527 ,  G01N27/44791

Abstract: The present invention is related to a method of separation of compounds by electrophoresis in which the compounds such as genes, proteins, etc. may be analyzed very precisely as samples are introduced directly into the separation tubes of the chip at the collection site, and therefore, it is not necessary to have separate fluid paths or individual sample storing apparatus that have been necessary for the conventional electrophoresis; it is easy to make the chip as the structure of the chip becomes extremely simple, and high-density arrangement of the separation tubes is enabled; and further, the compounds such as genes, proteins, etc. may be analyzed very precisely without interference in the storage tubs by using a non-polar solvent as the solvent of the sample storage tub.

Abstract translation: 本发明涉及通过电泳分离化合物的方法，其中可以非常精确地分析诸如基因，蛋白质等化合物，因为样品在采集部位直接引入芯片的分离管中，因此 ，不需要为常规电泳所必需的单独的流体路径或单独的样品存储装置; 由于芯片的结构变得非常简单，容易制造芯片，并且能够进行高密度的分离管的配置; 此外，通过使用非极性溶剂作为样品储存桶的溶剂，可以非常精确地分析诸如基因，蛋白质等化合物而不会干扰存储桶。

公开(公告)号：WO2006031061A1

公开(公告)日：2006-03-23

申请号：PCT/KR2005/003038

申请日：2005-09-14

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE ,  SONG, Nam Woong ,  KIM, Hyong-Ha

Inventor： SONG, Nam Woong ,  KIM, Hyong-Ha

IPC: C12Q1/68

CPC classification number: C12Q1/6813 ,  C12Q2531/113 ,  C12Q2563/107 ,  C12Q2565/628

Abstract: Disclosed herein is a method for screening a probe set for detecting a target gene using a FRET system, the method comprising the steps of: (A) determining one common primer to a complementary strand from the base sequence of a target gene and designing a plurality of different primers to a target strand; (B) mixing the primers with DNA containing the target gene and subjecting the mixtures to PCR so as to first screen primers to the target strand, which produce products; (C) mixing the first screened primers with one common primer to the com¬ plementary strand and DNA containing no target gene, subjecting the mixtures to PCR so as to second screen primers to the target strand, which produce no product; and (D) selecting any two primers from the group consisting of the second screened primers to the target strand and labeling the selected primers with an energy donor and energy acceptor for FRET test, re¬ spectively. The use of the method not only allows the reduction of enormous expense required for a gene labeling process but also can increase the accuracy and selectivity of a probe set to a target gene so as to perform a target gene detection process in a more rapid and easy manner.

Abstract translation: 本文公开了一种使用FRET系统筛选用于检测靶基因的探针组的方法，所述方法包括以下步骤：（A）从靶基因的碱基序列确定与互补链的一个共同引物并设计多个 不同的引物与目标链; （B）将引物与含有靶基因的DNA混合，并对混合物进行PCR，首先将引物筛选到产生产物的目标链上; （C）将第一筛选引物与一个共同引物与不含靶基因的DNA混合，使混合物进行PCR，以将第二筛选引物与不产生产物的靶链进行混合; 并且（D）选择任意两个引物，该引物由对目标链的第二筛选引物组成，并且用能量供体和能量受体对FRET试验进行标记所选择的引物。 该方法的使用不仅可以减少基因标记过程所需的巨大费用，而且可以提高探针对目标基因的精确度和选择性，从而以更快速和容易的方式进行靶基因检测过程 方式。

公开(公告)号：WO2002082017A1

公开(公告)日：2002-10-17

申请号：PCT/KR2002/000618

申请日：2002-04-09

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE ,  APPLIED CAPACITANCE CORPORATION ,  LEE, Rae-Duk

Inventor： LEE, Rae-Duk

IPC: G01C9/18

CPC classification number: G01C9/06 ,  G01C9/20 ,  G01C2009/062 ,  G01C2009/185

Abstract: This invention relates to a capacity sensor for measuring of inclination wherein such an inside electrode plate that it has guard-ring electrode in the circumference and also forms each couple of semicircular type inside electrode symmetrically in the front and rear of printing circuit plate is fixed to the center of metal ring for supporting an electrode, and an outside electrode having a guarding electrode in the circumference is placed against the inside electrode as such and also it is separated and fixed by designated distance for the inside electrode plate both sides of metal ring for supporting an electrode thereafter, the sensor structure is comprised by pouring liquid transmission display between inside electrode plate and outside electrode plate, and inside electrode and outside electrode is separated into a couple because liquid transmission display caused by inclination of the sensor is flown, whereby it can be measured an inclination on a basis of the change of electricity capacity between inside electrode and outside electrode.

Abstract translation: 本发明涉及一种用于测量倾斜度的容量传感器，其中在周边具有防护环电极并且在印刷电路板的前后对称地形成每对半圆形内部电极的内部电极板被固定到 用于支撑电极的金属环的中心，以及在周围具有防护电极的外部电极相对于内部电极被放置在内部电极上，并且以金属环的两侧的内部电极板的两侧分隔固定指定距离 此后支撑电极，传感器结构包括通过在内电极板和外电极板之间倾倒液体透过显示而将内部电极和外部电极分离为一对，因为由传感器的倾斜引起的液体传输显示被飞行，由此 可以根据电力的变化来测量倾斜度 内部电极和外部电极之间的容量。

公开(公告)号：WO2019103318A1

公开(公告)日：2019-05-31

申请号：PCT/KR2018/012474

申请日：2018-10-22

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： LEE, Dong-Hoon ,  PARK, Seongchong ,  HWANG, Jisoo ,  YOO, Jae-Keun

IPC: G02B27/10 ,  G02B27/14 ,  G02B27/28

Abstract: A color synthesizing apparatus includes a white light source configured to output a collimated beam, a line beam generator configured to receive the collimated beam and generate a line beam spatially separated depending on a wavelength, a first parabolic mirror configured to receive the line beam provided by the line beam generator and provide a parallel light, a second parabolic mirror configured to receive the parallel light of the first parabolic mirror and focus the received parallel light on a focal point, a spatial variable spectral filter disposed between the first parabolic mirror and the second parabolic mirror and configured to transmit different wavelengths depending on positions, and a spatial light modulator disposed between the spatial variable spectral filter and the second parabolic mirror and configured to provide different transmittances depending on the positions.

公开(公告)号：WO2016122046A1

公开(公告)日：2016-08-04

申请号：PCT/KR2015/002324

申请日：2015-03-11

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： LEE, Joo-In ,  SHIN, Yong-Hyeon

IPC: H01L51/56 ,  H01L21/203 ,  H01L21/02

CPC classification number: C23C14/26 ,  C23C14/243 ,  H01L51/001

Abstract: Provided is a linear evaporation deposition apparatus that includes a vacuum container including a slit extending in a first direction; an evaporation crucible inserted into the slit to be disposed inside the vacuum container, including a storage space to store a deposition material, being made of a conductive material, heating the deposition material to generate vapor, injecting the vapor through a plurality of nozzles parts each connecting with the storage space, and extending in the first direction; an induction heating coil generating an induced electric field, inductively heating the evaporation crucible, extending in the first direction, and being disposed outside the vacuum container to inductively heat the evaporation crucible; and a dielectric window coupled with a surrounding portion of the slit of the vacuum container to seal the vacuum container, being disposed between the induction heating coil and the evaporation crucible, passing through the induced electric field generated by the induction heating coil, and extending in the first direction.

Abstract translation: 提供一种线性蒸发沉积装置，其包括：真空容器，其包括沿第一方向延伸的狭缝; 插入到狭缝中的蒸发坩埚被设置在真空容器内部，包括用于存储沉积材料的存储空间，由导电材料制成，加热沉积材料以产生蒸气，通过多个喷嘴部分喷射蒸气 与存储空间连接并沿第一方向延伸; 产生感应电场的感应加热线圈，感应加热蒸发坩埚，沿第一方向延伸，并设置在真空容器的外面，以感应加热蒸发坩埚; 以及与真空容器的狭缝的周围部分耦合的电介质窗口，以密封真空容器，设置在感应加热线圈和蒸发坩埚之间，穿过感应加热线圈产生的感应电场，并延伸到 第一个方向。

公开(公告)号：WO2015030343A1

公开(公告)日：2015-03-05

申请号：PCT/KR2014/004267

申请日：2014-05-13

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： CHO, Yong Jai ,  CHEGAL, Won ,  CHO, Hyun Mo

IPC: G01N21/17

CPC classification number: G01N21/211 ,  G01J4/04 ,  G01N2021/213 ,  G01N2201/061 ,  G01N2201/0633 ,  G01N2201/0683 ,  G01N2201/11

Abstract: Provided is an optical element rotation type Mueller-matrix ellipsometer for solving a problem of measurement accuracy and measurement precision occurring due to residual polarization of a light source, polarization dependence of a photo-detector, measurement values of Fourier coefficients of a high order term in dual optical element rotation type Mueller-matrix ellipsometers according to the related art capable of measuring some or all of components of a Mueller-matrix for any sample.

Abstract translation: 提供一种光学元件旋转型米勒矩阵椭偏仪，用于解决由于光源的残余极化产生的测量精度和测量精度的问题，光检测器的偏振度依赖性，高阶项的傅里叶系数的测量值 根据相关技术的双光学元件旋转型米勒矩阵椭偏仪能够测量任何样品的Mueller矩阵的一些或全部组分。

公开(公告)号：WO2014189228A1

公开(公告)日：2014-11-27

申请号：PCT/KR2014/004331

申请日：2014-05-14

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： LEE, Joo-In ,  KIM, Jung-Hyung ,  YOO, Yong-Shim ,  YOU, ShinJae ,  SHIN, Yong-Hyeon

IPC: H01L51/56 ,  C23C14/24

CPC classification number: C23C14/243 ,  C23C14/12 ,  C23C14/26

Abstract: Provided is an evaporation deposition apparatus which includes an evaporation part providing an evaporation material through a connection path; a distribution part having a plurality of holes and injecting the evaporation material into a vacuum container through the holes; a dielectric part mounted in the vicinity of an opening of the vacuum container and disposed to protrude from the vacuum container and to cover the evaporation part and the distribution part; an induction coil covering the distribution part and the distribution part and inductively heating the evaporation part and the distribution part; and an alternating current (AC) power source supplying AC to the induction coil.

Abstract translation: 提供了一种蒸发沉积设备，其包括通过连接路径提供蒸发材料的蒸发部件; 分配部分具有多个孔并且通过所述孔将所述蒸发材料注入真空容器中; 绝缘部，安装在所述真空容器的开口附近并且设置成从所述真空容器突出并覆盖所述蒸发部和所述分配部; 覆盖分配部和分配部的感应线圈，并且感应加热蒸发部和分配部; 以及向感应线圈提供AC的交流（AC）电源。

公开(公告)号：WO2013058471A1

公开(公告)日：2013-04-25

申请号：PCT/KR2012/005899

申请日：2012-07-24

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE ,  RHEE, Hyug-Gyo ,  LEE, Yun Woo

Inventor： RHEE, Hyug-Gyo ,  LEE, Yun Woo

IPC: G03F7/20 ,  G03F7/26 ,  H01L21/027

CPC classification number: B29C59/16 ,  G03F7/70383 ,  G03F7/70408 ,  G03F7/70566

Abstract: The present invention relates to a fine pattern manufacturing apparatus using interference and a fine pattern manufacturing method using the fine pattern manufacturing apparatus, which can improve height direction resolution in a laser irradiation method. More specifically, the invention relates to a fine pattern manufacturing apparatus using interference and a fine pattern manufacturing method using the manufacturing apparatus, in which a height direction interference generation unit is included to interfere laser beams respectively having a different plane direction width, and height direction line width can be improved by irradiating an interference laser beam having an interference fringe direction of height direction on a photosensitive film.

Abstract translation: 本发明涉及使用干涉的精细图案制造装置和使用精细图案制造装置的精细图案制造方法，其能够提高激光照射方法中的高度方向分辨率。 更具体地，本发明涉及使用干涉的精细图案制造装置和使用该制造装置的精细图案制造方法，其中包括高度方向干涉产生单元以干扰分别具有不同的平面方向宽度的激光束和高度方向 可以通过在感光膜上照射具有高度方向的干涉条纹方向的干涉激光束来提高线宽。