Laminated molecular thin film of fatty acid and lipid to become substrate of biomolecular element and biosensor molecule, and method for producing the same
    71.
    发明专利
    Laminated molecular thin film of fatty acid and lipid to become substrate of biomolecular element and biosensor molecule, and method for producing the same 有权
    脂肪酸和脂肪的层压分子薄膜以生成生物分子元件和生物传感器分子的底物及其生产方法

    公开(公告)号:JP2007254347A

    公开(公告)日:2007-10-04

    申请号:JP2006080442

    申请日:2006-03-23

    Inventor: TSUJIUCHI YUTAKA

    CPC classification number: G01N33/544 B05D1/204 B82Y30/00 B82Y40/00

    Abstract: PROBLEM TO BE SOLVED: To obtain an organic thin film that becomes a molecular substrate, is flexible and has high strength in which a molecule of membrane protein as a biomolecular element or a biosensor functions in the same manner as in an organism and to provide a method for producing the organic thin film by tackling the difficult problem of a conventional method.
    SOLUTION: The organic thin film to become a substrate of a biomolecular element or a biosensor molecule is produced by forming a lipid molecule layer on a fatty acid molecular layer being a first kind thin film layer formed on an inorganic substrate. A thin film structure having a characteristic pattern structure is obtained by selection and combination of fatty acid molecules.
    COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题为了获得成为分子底物的有机薄膜,是柔性的并且具有高强度,其中膜蛋白作为生物分子元件或生物传感器的分子以与生物体相同的方式起作用, 以提供通过解决常规方法的困难问题来生产有机薄膜的方法。 解决方案:通过在作为在无机基材上形成的第一种薄膜层的脂肪酸分子层上形成脂质分子层来制备成为生物分子元件或生物传感器分子的底物的有机薄膜。 通过脂肪酸分子的选择和组合获得具有特征图案结构的薄膜结构。 版权所有(C)2008,JPO&INPIT

    Facility and method for depositing a film of ordered particles onto a moving substrate
    76.
    发明授权
    Facility and method for depositing a film of ordered particles onto a moving substrate 有权
    将有序颗粒膜沉积到移动的基底上的设备和方法

    公开(公告)号:US09505021B2

    公开(公告)日:2016-11-29

    申请号:US14001088

    申请日:2012-02-20

    Abstract: A facility for depositing a film of ordered particles onto a moving substrate, the facility including: a transfer area including an entry of particles and an exit of particles spaced apart from each other by two side edges facing each other, retaining a carrier liquid on which the particles float, a capillary bridge ensuring connection between the carrier liquid contained in the transfer area and the substrate, and a plurality of suction nozzles capable of attracting the particles towards its two side edges.

    Abstract translation: 一种用于将有序颗粒的膜沉积在移动的基底上的设备,该设备包括:传送区域,包括粒子的入口和通过彼此面对的两个侧边缘彼此间隔开的颗粒的出口,保持载体液体 颗粒浮动,确保包含在传送区域中的载体液体与基板之间的连接的毛细管桥和能够将颗粒吸引到其两个侧边缘的多个吸嘴。

    Method for producing a chromatography-enrichment column
    77.
    发明申请
    Method for producing a chromatography-enrichment column 有权
    色谱富集柱的制备方法

    公开(公告)号:US20150233876A1

    公开(公告)日:2015-08-20

    申请号:US14414853

    申请日:2013-07-02

    Abstract: The invention concerns a method for producing a chromatography-enrichment column, the method comprising the following steps: (a) depositing at least one layer of desired particles, which may be identical or different, and are intended to constitute the stationary phase, in a compact assembly, on the flat surface of a substrate; (b) crosslinking the layer in at least the regions corresponding to the desired shape of the enrichment column to be obtained; (c) impregnating the layer with a light radiation-sensitive material; (d) insolating the layer obtained in step (c) so as to form insolated regions of which the shape corresponds to the desired internal shape of the enrichment column, if the light radiation-sensitive material behaves like a positive resin or to form non-insolated regions of which the shape corresponds to the desired internal shape of the enrichment column if the light radiation-sensitive material behaves like negative resin; and (e) eliminating the light radiation-sensitive material in the zones corresponding to the internal shape of the enrichment column. The invention is used in particular in the field of chemical analysis.

    Abstract translation: 本发明涉及一种生产色谱 - 富集柱的方法,该方法包括以下步骤:(a)沉积至少一层可能相同或不同的期望的颗粒,并且旨在构成固定相 紧凑的组装,在基底的平坦表面上; (b)在至少对应于要获得的富集柱的所需形状的区域中交联该层; (c)用光辐射敏感材料浸渍该层; (d)使步骤(c)中获得的层剥离,以形成其形状对应于富集柱的所需内部形状的绝缘区域,如果光辐射敏感材料表现得像正树脂或形成非 - 如果光辐射敏感材料表现为负树脂,则其形状对应于富集柱的期望内部形状的其它区域; 和(e)消除对应于浓缩塔的内部形状的区域中的光辐射敏感材料。 本发明特别用于化学分析领域。

    SENSOR SYSTEM WITH PLASMONIC NANO-ANTENNA ARRAY
    80.
    发明申请
    SENSOR SYSTEM WITH PLASMONIC NANO-ANTENNA ARRAY 有权
    具有等离子体纳米天线阵列的传感器系统

    公开(公告)号:US20120050732A1

    公开(公告)日:2012-03-01

    申请号:US13214176

    申请日:2011-08-20

    Abstract: In order to provide the high sensitivity SERS active substrates needed for rapid and sensitive chemical/biological agent detection, the present invention provides a Plasmonic Nano-antenna Array (PNA) substrate with large local electromagnetic field enhancements; a controllable and repeatable nano-fabrication process for creating the PNA surface; and a system design for a compact, portable device capable of using the PNA technology to acquire and analyze target molecular samples. Both 2D and 3D systems are provided.

    Abstract translation: 为了提供快速和敏感的化学/生物试剂检测所需的高灵敏度SERS活性底物,本发明提供了具有大的局部电磁场增强的等离子体纳米天线阵列(PNA)衬底; 用于产生PNA表面的可控和可重复的纳米制造工艺; 以及能够使用PNA技术获取和分析目标分子样品的紧凑便携式设备的系统设计。 提供2D和3D系统。

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