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81.发明公开公开(公告)号：US20230210371A1
公开(公告)日：2023-07-06
申请号：US18072838
申请日：2022-12-01
Applicant: University of Houston System
Inventor： Kirill V. Larin , Manmohan Singh , Jiasong Li , Zhaolong Han , Michael D. Twa
CPC classification number: A61B3/18 , A61B3/165 , A61B3/102 , A61B5/7289 , A61B5/7246
Abstract: Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.
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公开(公告)号：US11692155B1
公开(公告)日：2023-07-04
申请号：US17745714
申请日：2022-05-16
Applicant: University of Houston System
Inventor： Zhifeng Ren
CPC classification number: C11D3/14 , C11D7/20 , C11D7/26 , C11D11/0047 , C11D17/0004 , C11D17/0013 , B82Y40/00
Abstract: A cleaning composition is provided herein. The cleaning composition includes a plurality of metal particles and a base fluid. The plurality of metal particles have an average size in a range of from about 1 nanometer (nm) to about 10,000 micrometers (μm), and are dispersed in the base fluid. The cleaning composition is configured to generate an exothermic reaction when contacted with one or more components on a surface and water to facilitate removal of the one or more components from the surface. Methods of making and utilizing the cleaning composition are also provided.
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公开(公告)号：US20230181728A1
公开(公告)日：2023-06-15
申请号：US17925082
申请日：2021-05-25
Applicant: University of Houston System , Tulane University
Inventor： Colin N. Haile , Gregory Cuny , Elizabeth B. Norton , Therese Kosten
CPC classification number: A61K39/385 , A61K39/0013 , A61K39/39 , A61K47/42 , A61K47/6415 , A61K47/646 , A61P25/36 , A61P37/04 , A61K2039/6037 , A61K2039/55544 , A61K2039/575 , A61K2039/541 , A61K2039/543
Abstract: The adjuvanted conjugate opioid vaccine described herein is a conjugate of a protein carrier and at least one opioid backbone component or hapten conjugated thereto, admixed with at least one adjuvant. Anti-opioid effects are demonstrated after administration of a vaccine made up of the CRM197 protein carrier linked to a FEN backbone, combined with adjuvants such as dmLT or LTA1.
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公开(公告)号：US11660325B2
公开(公告)日：2023-05-30
申请号：US16334528
申请日：2017-09-19
Inventor： Damith Gomika Udugamasooriya , Aaron Raymond , John Minna
Abstract: Described herein are pharmaceutical compositions containing peptoids of general formula (I), (II), or (III) capable of reducing proliferation of cancer stem cells in a subject and methods of treatment or prophylactic administration of these pharmaceutical compositions to treat cancer. Also provided herein are method of detecting and treating cancerous cell masses by use of peptoids of general formula (I), (II), or (III).
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公开(公告)号：US20230121081A1
公开(公告)日：2023-04-20
申请号：US17962597
申请日：2022-10-10
Applicant: University of Houston System
Inventor： Pranav J. Parikh
Abstract: A hand function testing device includes a base having a number of rigid wires protruding from a surface thereof, each rigid wire having a stationary bead affixed at a predetermined position along the rigid wire, a moving bead movably mounted on the rigid wire and movable along a working region of the rigid wire defined between a base-end of the rigid wire and the stationary bead, the moving bead being mounted on the rigid wire via reception of the rigid wire through a lumen in the moving bead, and at least one force sensing element for measuring a force input to the moving bead. A method of testing hand function includes using the hand function testing device to measure a force input to a moving bead as the moving bead is moved within a working region on the rigid wire.
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Patent Agency Ranking
公开(公告)号：US11627691B2
公开(公告)日：2023-04-11
申请号：US15999846
申请日：2017-02-17
Applicant: University of Houston System
Inventor： Zhifeng Ren , Jing Shuai
IPC: H10N10/852 , C22C12/00 , H10N10/853 , C22C28/00 , B22F3/15 , B22F1/054 , B22F9/04
Abstract: Systems and methods discussed herein relate to Zintl-type thermoelectric materials, including a p-type thermoelectric material according to the formula AMyXy, and includes at least one of calcium (Ca), europium (Eu), ytterbium (Yb), and strontium (Sr), and has a ZT of the above about 0.60 above 675K. The n-type thermoelectric component includes magnesium (Mg), tellurium (Te), antimony (Sb), and bismuth (Bi) according to the formula Mg3.2Sb1.3Bi0.5-xTex that has an average ZT above 0.8 from 400K to 800K. The p-type and n-type materials discussed herein may be used alone, in combination with other materials, or in combination with each other in various configurations.
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公开(公告)号：US20230088763A1
公开(公告)日：2023-03-23
申请号：US17932889
申请日：2022-09-16
Applicant: University of Houston System
Inventor： Mohammad Reza ABIDIAN , Omid DADRAS-TOUSSI , Milad KHORRAMI , Sheereen MAJD
IPC: C09D11/52 , G01N33/543
Abstract: The present disclosure describes a new resin which can be fabricated into conductive and bioactive microstructures via two-photon polymerization. The direct incorporation of conductive poly (3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) and/or multi-walled carbon nanotubes (MWCNTs) in a poly(ethylene glycol) diacrylate (PEGDA)-based blend remarkably enhances the electrical conductivity of microstructures over 10 orders of magnitude. Including biomaterials in the resin can promote cellular adhesion and create functional biosensors made of hybrid non-conductive and conductive structures for sensitive detection. Applications include development cost effective microelectronics in a broad range of biomedical research, electronics and sensors.
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公开(公告)号：US20230054218A1
公开(公告)日：2023-02-23
申请号：US17980185
申请日：2022-11-03
Applicant: UNIVERSITY OF HOUSTON SYSTEM
Inventor： Gangbing Song , Siu Chun Michael Ho , Devendra Patil
Abstract: Systems and methods for the ultrasonic disruption of biofilm and algae growth on underwater structures utilize an ultrasonic actuator that produces a natural frequency in the ultrasonic range. In some embodiments, the ultrasonic actuator includes one or more piezoelectric transducers.
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公开(公告)号：US20230030968A1
公开(公告)日：2023-02-02
申请号：US17878258
申请日：2022-08-01
Applicant: University of Houston System
Inventor： Jeffrey D. Rimer , Xi Geng , Ricardo Sosa
IPC: C02F5/10
Abstract: Analogues of citrate, namely hydroxycitrate (HCA) and isocitrate (ICA), have dual roles as nucleation inhibitors and growth suppressors in the formation of mineral scale. Their potency is comparable to commercial phosphorous-based inhibitors, but they are more environmentally friendly, which has practical advantages for use in a broad range of commercial applications.
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90.发明申请公开(公告)号：US20230028081A1
公开(公告)日：2023-01-26
申请号：US17812932
申请日：2022-07-15
Applicant: University of Houston System
Inventor： Mohammad Reza ABIDIAN , Mohammadjavad ESLAMIAN , Sheereen MAJD
Abstract: In one aspect, the present disclosure provides organic semiconductors (OSNTs) as well as high-performance electrochemical devices based on the present OSNTs for the production of micro and nano-scale actuators. The present OSNTs may be used in several applications, including movable and implantable interface devices, such as flexible neural microelectrodes. Also provided herein are flexible neural microelectrodes based on conjugated polymer actuators
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