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公开(公告)号：WO2020130208A1
公开(公告)日：2020-06-25
申请号：PCT/KR2018/016476
申请日：2018-12-21
Applicant: 아쿠아그린텍(주)
Inventor： 장지태
IPC: A23L33/00 , A61K36/03 , A23L33/105
Abstract: 감태추출물을 포함하고, 상기 감태추출물이 주정추출물이며, 상기 감태추출물이 피로갈롤-플로로글루시놀-6,6'-비엑콜(PPB, pyrogallol-phloroglucinol-6,6'-bieckol)을 포함하는 식이조절용 조성물을 제공한다. 또한, 상기 식이조절용 조성물을 제공하기 위한 제조방법으로서, 40중량% 초과, 100중량% 이하의 알코올 조성물을 함유한 용매를 준비하는 단계; 및 상기 용매를 이용하여 감태 원료를 주정추출하여 감태추출물을 얻는 단계;를 포함하는 식이조절용 조성물의 제조방법을 제공한다.
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公开(公告)号：WO2022244913A1
公开(公告)日：2022-11-24
申请号：PCT/KR2021/009083
申请日：2021-07-15
Applicant: 아쿠아그린텍(주)
Inventor： 장지태
IPC: A61K36/03 , A61P21/00 , A23L33/105
Abstract: 본 발명은 감태(Ecklonia cava) 주정 추출물을 유효성분으로 함유하는 노인성 근감소증(age-related sarcopenia) 예방 또는 치료용 조성물에 관한 것으로, 감태 주정 추출물은 노화가 본격적으로 시작되는 연령대의 개체에서 근력 및 다리 근육의 무게를 증가시키고, 근육 단백질 합성에 관여하는 mRNA 발현을 증가시키고, 근육 단백질 분해에 관여하는 mRNA 발현을 감소시켜 노인성 근감소증(age-related sarcopenia)의 예방 또는 치료 효과를 나타낸다.
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3.发明授权디에콜을 함유하는 감태 추출물 또는 감태 유래 디에콜을 포함하는 탈모방지 또는 발모촉진용 조성물 有权用于预防脱发或刺激包含Ecklonia Cava提取物的Diekol或Diekol来自Ecklonia cava的组合物
公开(公告)号：KR101247239B1
公开(公告)日：2013-03-26
申请号：KR1020100118404
申请日：2010-11-25
Applicant: 아쿠아그린텍(주)
Abstract: 본 발명은 탈모방지 또는 발모촉진용 조성물 및 이의 제조방법에 관한 것으로, 더욱 상세하게는 디에콜을 함유하는 탈모방지 또는 발모촉진용 조성물 및 이의 제조방법에 관한 것이다. 상기 디에콜을 함유하는 탈모방지 또는 발모촉진용 조성물의 제조방법은 (a) 감태에 당 분해효소를 첨가하여 효소 추출물을 제조하는 단계; (b) 상기 효소 추출물을 여과하고, 동결건조시키는 단계; 및 (c) 상기 동결건조된 효소 추출물을 유기용매로 추출하여 디에콜을 함유하는 감태 추출물을 제조하는 단계를 포함하는 것을 특징으로 한다.
본 발명에 따른 감태에서 분리된 활성물질인 디에콜은 모발 개선 효과의 지표가 되는 5알파-리덕타제 억제 활성에 대한 우수한 효과를 가지며, 특히 상업용 5알파-리덕타제인 피나스테라이드(finasteride)와 유사한 활성을 가지므로, 해양천연물 유래의 새로운 육모 및 모발 개선 소재로서의 이용가능성이 있다.-
公开(公告)号：KR1020100021260A
公开(公告)日：2010-02-24
申请号：KR1020080080083
申请日：2008-08-14
Abstract: PURPOSE: A method for drying far infrared ray of Ecklonia cava and ethanol extract of far infrared ray-dried Ecklonia cava are provided to reduce time and cost comparing to freeze-drying method. CONSTITUTION: An ethanol extract of Ecklonia cava by far infrared ray drying is obtained by extracting at 40-60°C for 4-6 hours. The ethanol extract of Ecklonia cava has increased dieckol and eckol content. A method for preparing ethanol extract of Ecklonia cava comprises: a step of washing Ecklonia cava sample; a step of drying Ecklonia cava through far infrared ray; a step of free-drying the Ecklonia cava; a step of pulverizing the dried Ecklonia cava; a step of homogenizing at room temperature for 24 hours; a step of filtering with Whatman No.1; a step of centrifuging at 3500rpm for 20 minutes; and a step of removing ethanol.
Abstract translation: 目的：提供远红外线干燥的Ecklonia cava远红外线Ecklonia cava和乙醇提取物的干燥方法，以减少与冷冻干燥法相比的时间和成本。 构成：通过远红外线干燥得到Ecklonia cava的乙醇提取物，在40-60℃下萃取4-6小时。 Ecklonia cava的乙醇提取物增加了甲羟戊酸和eckol含量。 Ecklonia cava乙醇提取物的制备方法包括：洗涤Ecklonia cava样品的步骤; 通过远红外线干燥Ecklonia cava的一个步骤; Ecklonia Cava自由干燥的一步; 粉碎干燥的Ecklonia cava的步骤; 在室温下均化24小时的步骤; 与Whatman No.1过滤的一个步骤; 在3500rpm离心20分钟的步骤; 和除去乙醇的步骤。
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公开(公告)号：KR101088442B1
公开(公告)日：2011-11-30
申请号：KR1020080087534
申请日：2008-09-05
Applicant: 아쿠아그린텍(주)
Abstract: 본 발명은 사료 첨가물, 이의 제조방법 및 이를 포함하는 사료에 관한 것으로서, 특히, 감태의 발효를 이용한 사료 첨가물, 이의 제조방법 및 이를 포함하는 사료에 관한 것으로서, 감태발효체를 주성분으로 포함하는 것을 특징으로 하는 감태발효 사료첨가물 및 이의 제조방법, 감태발효체를 주성분으로 포함하는 감태발효 사료첨가물을 포함하는 것을 특징으로 하는 사료 등을 제공한다.
감태가공부산물, 감태발효 사료첨가제, 사료.-
Patent Agency Ranking
公开(公告)号：KR1020100028690A
公开(公告)日：2010-03-15
申请号：KR1020080087534
申请日：2008-09-05
Applicant: 아쿠아그린텍(주)
Abstract: PURPOSE: Feed additives containing fermented Ecklonia cava and a manufacturing method thereof are provided to improve antibacterial effects about bacteria and immune cell proliferation effects about livestock or fish, and to improve fodder efficiency. CONSTITUTION: Feed additives contain 2~ 10 weight% of fermented Ecklonia cava. A manufacturing method of the feed additives includes the following steps: preparing Ecklonia cava processing products or Ecklonia cava; drying the prepared Ecklonia cava or Ecklonia cava processing products; pulverizing the Ecklonia cava or the dried Ecklonia cava processing products; adding water and fermentation bacteria in the powder of the Ecklonia cava; and fermenting the Ecklonia cava powder. A fermentation process of the Ecklonia cava powder is performed for 5 ~ 7 hours.
Abstract translation: 目的：提供含有发酵的Ecklonia cava的饲料添加剂及其制备方法，以改善细菌对细菌的抗菌效果和对牲畜或鱼类的免疫细胞增殖作用，提高饲料效率。 构成：饲料添加剂含有2〜10重量％的发酵的Ecklonia cava。 饲料添加剂的制造方法包括以下步骤：制备Ecklonia cava加工产品或Ecklonia cava; 干燥准备的Ecklonia卡瓦或Ecklonia卡瓦加工产品; 粉碎Ecklonia卡瓦或干燥的Ecklonia卡瓦加工产品; 在Ecklonia卡瓦粉末中加水和发酵细菌; 并发酵Ecklonia卡瓦粉。 Ecklonia Cava粉末的发酵过程进行5〜7小时。
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7.发明公开
公开(公告)号：KR1020130012417A
公开(公告)日：2013-02-04
申请号：KR1020110073612
申请日：2011-07-25
Applicant: 아쿠아그린텍(주) , 제주대학교 산학협력단
IPC: A61K31/737 , A61K36/03 , A61P37/00
CPC classification number: A61K31/737 , A61K36/03 , A61K2121/00 , Y10S514/885 , Y10S514/917
Abstract: PURPOSE: A composition containing Ecklonia cava-derived fucoidan for enhancing immunity is provided to ensure a radiation protecting ability and to be used as a material for enhancing immunity. CONSTITUTION: A composition with a radiation protecting ability contains Ecklonia cava extract-derived fucoidan. The fucoidan is prepared by extracting pulverized Ecklonia cava by enzyme extraction using saccharolytic enzyme, protease, or a mixture thereof. The saccharolytic enzyme includes celluclast, AMG, viscozyme, or a mixture thereof. The protease is alkalase, neutrase, flavourzyme, protamex, or a mixture thereof. The fucoidan is prepared by treating a fucoidan crude extract with potassium chloride and removing alginic acid. The fucoidan contains 45-55 wt% of polysaccharides and 15-20 wt% of a sulfate group. [Reference numerals] (AA) Ecklonia cava; (BB,JJ) Freeze-drying; (CC) Adding enzyme and reacting for 24 hours; (DD) Enzyme extract; (EE) Forming fractions using a membrane separator; (FF) Fractions by molecular weight; (GG) Separating fucoidan crude extract after removing low molecular products and pigment using ethanol; (HH) Removing alginic acid using calcium chloride; (II) Refining fucoidan without the alginic acid; (KK) Investigating characteristic
Abstract translation: 目的：提供含有Ecklonia cava来源的岩藻依聚糖用于增强免疫力的组合物，以确保辐射防护能力，并用作增强免疫力的材料。 构成：具有辐射防护能力的组合物含有Ecklonia cava提取物衍生的岩藻依聚糖。 岩藻依聚糖通过使用蔗糖分解酶，蛋白酶或其混合物的酶提取提取粉碎的埃克氏杆菌来制备。 蔗糖酶包括celluclast，AMG，粘蛋白酶或其混合物。 蛋白酶是碱性酶，中性酶，flavourzyme，protamex或它们的混合物。 通过用氯化钾处理岩藻依聚糖粗提物并除去海藻酸制备岩藻依聚糖。 岩藻依聚糖含有45-55wt％的多糖和15-20wt％的硫酸根。 （AA）Ecklonia cava; （BB，JJ）冷冻干燥; （CC）加酶并反应24小时; （DD）酶提取物; （EE）使用膜分离器形成级分; （FF）分子量分数; （GG）使用乙醇除去低分子产物和颜料后分离岩藻依聚糖粗提物; （HH）使用氯化钙去除海藻酸; （II）不含藻酸的精制岩藻多糖; （KK）调查特征
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公开(公告)号：KR1020120058695A
公开(公告)日：2012-06-08
申请号：KR1020100118404
申请日：2010-11-25
Applicant: 아쿠아그린텍(주)
Abstract: PURPOSE: A composition for preventing alopecia or promoting hair growth is provided to suppress 5 alpha-reductase and to ensure similar activity with finasteride. CONSTITUTION: A method for preparing a composition containing dieckol for preventing alopecia or promoting hair growth comprises: a step of adding saccharolytic enzyme to Ecklonia cava to prepare enzyme extrac(S100)t; a step of filtering and freeze-drying; and a step of extracting the enzyme extract with organic solvent. The saccharolytic enzyme is celluclast(S200). A composition for preventing alopecia or promoting hair growth contains dieckol.
Abstract translation: 目的：提供一种用于预防脱发或促进毛发生长的组合物以抑制5α-还原酶并确保与非那雄胺类似的活性。 构成：用于制备含有甲羟戊酸以防止脱发或促进毛发生长的组合物的方法包括：将蔗糖分解酶加入埃克氏杆菌来制备酶促提取物的步骤（S100）t; 过滤冷冻干燥步骤; 和用有机溶剂提取酶提取物的步骤。 蔗糖酶是celluclast（S200）。 用于预防脱发或促进毛发生长的组合物含有甲羟戊酸。
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公开(公告)号：KR100904759B1
公开(公告)日：2009-06-29
申请号：KR1020080111952
申请日：2008-11-12
Applicant: 아쿠아그린텍(주)
CPC classification number: A61K8/97 , A61K36/03 , A61K2236/19 , A61Q19/02 , Y10S514/844
Abstract: A cosmetic composition for skin whitening which contains an Ecklonia cava extract is provided to ensure excellent whitening effect by using fluro tannin based polyphenol-containing extract. A method for manufacturing a cosmetic composition of skin whitening which contains an Ecklonia cava extract comprises: a step of adding saccharolytic enzyme to an ecklonia cava to extract the Ecklonia cava; a step of removing and filtering residue and freeze-drying the enzyme extract; and a step of extracting the extract with organic solvent. The method further comprises: a step of eluting in diethylether through a column filled with cellite to fraction an active ingredient; and a step of eluting with chloroform and methanol in a ratio of 2:1-0:1 through a column filled with sephadex to fraction the active ingredient.
Abstract translation: 提供含有Ecklonia cava提取物的用于皮肤美白的化妆品组合物，以通过使用含有单宁鞣酸的多酚提取物来确保优异的美白效果。 含有Ecklonia Cava提取物的皮肤美白化妆品组合物的制造方法包括：将蔗糖分解酶加入到ecklonia cava中以提取Ecklonia cava的步骤; 去除和过滤残留物并冷冻干燥酶提取物的步骤; 和用有机溶剂提取提取物的步骤。 该方法还包括：在乙醚中通过填充有细胞的柱分离活性成分的步骤; 和用氯仿和甲醇以2：1-0：1的比例通过填充有sephadex的柱洗脱以分离活性成分的步骤。
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公开(公告)号：KR1020090030831A
公开(公告)日：2009-03-25
申请号：KR1020070096437
申请日：2007-09-21
Applicant: 아쿠아그린텍(주)
Inventor： 전유진
Abstract: An antihypertensive composition is provided to secure an effect of hypertension suppression by blocking a process of an Angiotensin I-Converting Enzyme becoming an Angiotensin II. An antihypertensive composition comprises styela clava extract. The styela clava extract is extracted by water or an organic solvent such as a 70% ethanol. The styela clava extract is extracted at a temperature of 20°C or 70°C. A method for preparing the styela clava extract is composed of the following steps of: washing the styela clava; freeze-drying the styela clava; and pulverizing the styela clava to obtain powder type extract.
Abstract translation: 提供抗高血压组合物以通过阻断成为血管紧张素II的血管紧张素转化酶的过程来确保高血压抑制的作用。 抗高血压组合物包含苯乙醇提取物。 石斛提取物用水或有机溶剂如70％乙醇萃取。 在20℃或70℃的温度下提取石蕊提取物。 一种制备石蕊提取物的方法包括以下步骤：洗涤苯乙烯; 冷冻干燥styela clava; 并粉碎苯甲酸钠以获得粉末型提取物。
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