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1.发明授权디에콜을 함유하는 감태 추출물 또는 감태 유래 디에콜을 포함하는 탈모방지 또는 발모촉진용 조성물 有权用于预防脱发或刺激包含Ecklonia Cava提取物的Diekol或Diekol来自Ecklonia cava的组合物
公开(公告)号：KR101247239B1
公开(公告)日：2013-03-26
申请号：KR1020100118404
申请日：2010-11-25
Applicant: 아쿠아그린텍(주)
Abstract: 본 발명은 탈모방지 또는 발모촉진용 조성물 및 이의 제조방법에 관한 것으로, 더욱 상세하게는 디에콜을 함유하는 탈모방지 또는 발모촉진용 조성물 및 이의 제조방법에 관한 것이다. 상기 디에콜을 함유하는 탈모방지 또는 발모촉진용 조성물의 제조방법은 (a) 감태에 당 분해효소를 첨가하여 효소 추출물을 제조하는 단계; (b) 상기 효소 추출물을 여과하고, 동결건조시키는 단계; 및 (c) 상기 동결건조된 효소 추출물을 유기용매로 추출하여 디에콜을 함유하는 감태 추출물을 제조하는 단계를 포함하는 것을 특징으로 한다.
본 발명에 따른 감태에서 분리된 활성물질인 디에콜은 모발 개선 효과의 지표가 되는 5알파-리덕타제 억제 활성에 대한 우수한 효과를 가지며, 특히 상업용 5알파-리덕타제인 피나스테라이드(finasteride)와 유사한 활성을 가지므로, 해양천연물 유래의 새로운 육모 및 모발 개선 소재로서의 이용가능성이 있다.-
公开(公告)号：KR1020100021260A
公开(公告)日：2010-02-24
申请号：KR1020080080083
申请日：2008-08-14
Abstract: PURPOSE: A method for drying far infrared ray of Ecklonia cava and ethanol extract of far infrared ray-dried Ecklonia cava are provided to reduce time and cost comparing to freeze-drying method. CONSTITUTION: An ethanol extract of Ecklonia cava by far infrared ray drying is obtained by extracting at 40-60°C for 4-6 hours. The ethanol extract of Ecklonia cava has increased dieckol and eckol content. A method for preparing ethanol extract of Ecklonia cava comprises: a step of washing Ecklonia cava sample; a step of drying Ecklonia cava through far infrared ray; a step of free-drying the Ecklonia cava; a step of pulverizing the dried Ecklonia cava; a step of homogenizing at room temperature for 24 hours; a step of filtering with Whatman No.1; a step of centrifuging at 3500rpm for 20 minutes; and a step of removing ethanol.
Abstract translation: 目的：提供远红外线干燥的Ecklonia cava远红外线Ecklonia cava和乙醇提取物的干燥方法，以减少与冷冻干燥法相比的时间和成本。 构成：通过远红外线干燥得到Ecklonia cava的乙醇提取物，在40-60℃下萃取4-6小时。 Ecklonia cava的乙醇提取物增加了甲羟戊酸和eckol含量。 Ecklonia cava乙醇提取物的制备方法包括：洗涤Ecklonia cava样品的步骤; 通过远红外线干燥Ecklonia cava的一个步骤; Ecklonia Cava自由干燥的一步; 粉碎干燥的Ecklonia cava的步骤; 在室温下均化24小时的步骤; 与Whatman No.1过滤的一个步骤; 在3500rpm离心20分钟的步骤; 和除去乙醇的步骤。
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公开(公告)号：KR101088442B1
公开(公告)日：2011-11-30
申请号：KR1020080087534
申请日：2008-09-05
Applicant: 아쿠아그린텍(주)
Abstract: 본 발명은 사료 첨가물, 이의 제조방법 및 이를 포함하는 사료에 관한 것으로서, 특히, 감태의 발효를 이용한 사료 첨가물, 이의 제조방법 및 이를 포함하는 사료에 관한 것으로서, 감태발효체를 주성분으로 포함하는 것을 특징으로 하는 감태발효 사료첨가물 및 이의 제조방법, 감태발효체를 주성분으로 포함하는 감태발효 사료첨가물을 포함하는 것을 특징으로 하는 사료 등을 제공한다.
감태가공부산물, 감태발효 사료첨가제, 사료.-
公开(公告)号：KR1020100028690A
公开(公告)日：2010-03-15
申请号：KR1020080087534
申请日：2008-09-05
Applicant: 아쿠아그린텍(주)
Abstract: PURPOSE: Feed additives containing fermented Ecklonia cava and a manufacturing method thereof are provided to improve antibacterial effects about bacteria and immune cell proliferation effects about livestock or fish, and to improve fodder efficiency. CONSTITUTION: Feed additives contain 2~ 10 weight% of fermented Ecklonia cava. A manufacturing method of the feed additives includes the following steps: preparing Ecklonia cava processing products or Ecklonia cava; drying the prepared Ecklonia cava or Ecklonia cava processing products; pulverizing the Ecklonia cava or the dried Ecklonia cava processing products; adding water and fermentation bacteria in the powder of the Ecklonia cava; and fermenting the Ecklonia cava powder. A fermentation process of the Ecklonia cava powder is performed for 5 ~ 7 hours.
Abstract translation: 目的：提供含有发酵的Ecklonia cava的饲料添加剂及其制备方法，以改善细菌对细菌的抗菌效果和对牲畜或鱼类的免疫细胞增殖作用，提高饲料效率。 构成：饲料添加剂含有2〜10重量％的发酵的Ecklonia cava。 饲料添加剂的制造方法包括以下步骤：制备Ecklonia cava加工产品或Ecklonia cava; 干燥准备的Ecklonia卡瓦或Ecklonia卡瓦加工产品; 粉碎Ecklonia卡瓦或干燥的Ecklonia卡瓦加工产品; 在Ecklonia卡瓦粉末中加水和发酵细菌; 并发酵Ecklonia卡瓦粉。 Ecklonia Cava粉末的发酵过程进行5〜7小时。
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公开(公告)号：KR101620275B1
公开(公告)日：2016-05-11
申请号：KR1020150115794
申请日：2015-08-18
Applicant: 아쿠아그린텍(주)
IPC: A61K36/03 , A61K31/737 , A23L1/30
Abstract: 본발명은항산화, 면역증강및 항염효과가모두우수한감태유래폴리페놀및 후코이단혼합조성물을단일추출공정으로제조하는방법에관한것으로, 구체적으로, 분말화된감태를열수추출후 별도의여과단계없이가수분해효소를투여하고생성된효소가수분해물을여과및 농축하는단계를포함한다.
Abstract translation: 本发明涉及一种具有优异的抗氧化，免疫刺激和抗炎作用的单克隆提取方法，用于制备Ecklonia cava来源的多酚和岩藻依聚糖的混合组合物的方法。 更具体地说，该方法包括以下步骤：在用热水提取粉状的Ecklonia cava之后，不用额外的过滤步骤插入水解酶; 并过滤并浓缩生产的酶水解产物。
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Patent Agency Ranking
公开(公告)号：KR101088437B1
公开(公告)日：2011-12-01
申请号：KR1020080084376
申请日：2008-08-28
Applicant: 아쿠아그린텍(주)
Abstract: 본 발명은 양어용 배합사료(Extruded pellet, EP사료)의 단점을 보완하기 위하여 목초액, 키토산, 단백분해효소가 함유된 기능성 코팅제 조성물과 이를 코팅하여 얻어지는 배합사료에 관한 것으로, 이러한 코팅제 조성물로 배합사료를 코팅하게 되면 배합사료 중 포함된 단백질의 유출을 최대한 억제할 수 있고, 배합사료에 첨가하는 글루타치온 등 유용성분의 해수 유출도 최소화 할 수 있으며, 이러한 배합사료를 급이하여 넙치 등 어류를 양식하면 어류의 성장이 촉진되고, 어류 면역증강효과가 나타나 폐사율도 감소시키는 효과가 있다.
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7.发明公开감태의 효소가수분해물 제조방법，이를 이용한 감태 유래 후코이단의 제조방법 및 감태 유래 후코이단 无效ECKLONIC CAVA的加工水解方法，使用该方法的ECKLONIA CAVA FUCOIDAN的方法和ECKLONIA CAVA FUCOIDAN
公开(公告)号：KR1020110075541A
公开(公告)日：2011-07-06
申请号：KR1020090132020
申请日：2009-12-28
Applicant: 아쿠아그린텍(주)
Abstract: PURPOSE: A method for preparing Ecklonia cava hydrolysate and fudoidan from Ecklonia cava are provided to improve anti-inflammation and physiological activity of immune modulation. CONSTITUTION: A method for preparing Ecklonia cava hydrolysate comprises: a step of washing Ecklonia cava and freeze-dyring Ecklonia cava(1,2); a step of pulverizing Ecklonia cava(3); a step of homogenizing pulverized Ecklonia cava(4); a step of adding 1-10 weight parts of saccharolytic enzyme to 100 weight parts of pulverized Ecklonia cava for enzyme reaction at pH 4.0-6.0 and 40-60°C for 12-24 hours(5); a step of boiling at 90-100°C for 10-60 minutes and stopping reaction(6); and a step of centrifuging at 3500-4000 rpm for 15-20 minutes.
Abstract translation: 目的：提供Ecklonia Cava水解物和Ecklonia cava的fudoidan的方法，以改善免疫调节的抗炎和生理活性。 构成：Ecklonia Cava水解产物的制备方法包括：洗涤Ecklonia cava和冷冻诱导Ecklonia cava（1,2）的步骤; Ecklonia cava粉碎步骤（3）; 匀化粉碎的Ecklonia cava的步骤（4）; 向100重量份的粉碎的Ecklonia卡瓦中添加1-10重量份的糖分解酶，在pH 4.0-6.0和40-60℃下反应12-24小时（5）; 在90-100℃下煮沸10-60分钟并停止反应（6）的步骤; 和以3500-4000rpm离心15-20分钟的步骤。
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8.发明公开
公开(公告)号：KR1020130012417A
公开(公告)日：2013-02-04
申请号：KR1020110073612
申请日：2011-07-25
Applicant: 아쿠아그린텍(주) , 제주대학교 산학협력단
IPC: A61K31/737 , A61K36/03 , A61P37/00
CPC classification number: A61K31/737 , A61K36/03 , A61K2121/00 , Y10S514/885 , Y10S514/917
Abstract: PURPOSE: A composition containing Ecklonia cava-derived fucoidan for enhancing immunity is provided to ensure a radiation protecting ability and to be used as a material for enhancing immunity. CONSTITUTION: A composition with a radiation protecting ability contains Ecklonia cava extract-derived fucoidan. The fucoidan is prepared by extracting pulverized Ecklonia cava by enzyme extraction using saccharolytic enzyme, protease, or a mixture thereof. The saccharolytic enzyme includes celluclast, AMG, viscozyme, or a mixture thereof. The protease is alkalase, neutrase, flavourzyme, protamex, or a mixture thereof. The fucoidan is prepared by treating a fucoidan crude extract with potassium chloride and removing alginic acid. The fucoidan contains 45-55 wt% of polysaccharides and 15-20 wt% of a sulfate group. [Reference numerals] (AA) Ecklonia cava; (BB,JJ) Freeze-drying; (CC) Adding enzyme and reacting for 24 hours; (DD) Enzyme extract; (EE) Forming fractions using a membrane separator; (FF) Fractions by molecular weight; (GG) Separating fucoidan crude extract after removing low molecular products and pigment using ethanol; (HH) Removing alginic acid using calcium chloride; (II) Refining fucoidan without the alginic acid; (KK) Investigating characteristic
Abstract translation: 目的：提供含有Ecklonia cava来源的岩藻依聚糖用于增强免疫力的组合物，以确保辐射防护能力，并用作增强免疫力的材料。 构成：具有辐射防护能力的组合物含有Ecklonia cava提取物衍生的岩藻依聚糖。 岩藻依聚糖通过使用蔗糖分解酶，蛋白酶或其混合物的酶提取提取粉碎的埃克氏杆菌来制备。 蔗糖酶包括celluclast，AMG，粘蛋白酶或其混合物。 蛋白酶是碱性酶，中性酶，flavourzyme，protamex或它们的混合物。 通过用氯化钾处理岩藻依聚糖粗提物并除去海藻酸制备岩藻依聚糖。 岩藻依聚糖含有45-55wt％的多糖和15-20wt％的硫酸根。 （AA）Ecklonia cava; （BB，JJ）冷冻干燥; （CC）加酶并反应24小时; （DD）酶提取物; （EE）使用膜分离器形成级分; （FF）分子量分数; （GG）使用乙醇除去低分子产物和颜料后分离岩藻依聚糖粗提物; （HH）使用氯化钙去除海藻酸; （II）不含藻酸的精制岩藻多糖; （KK）调查特征
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公开(公告)号：KR1020120058695A
公开(公告)日：2012-06-08
申请号：KR1020100118404
申请日：2010-11-25
Applicant: 아쿠아그린텍(주)
Abstract: PURPOSE: A composition for preventing alopecia or promoting hair growth is provided to suppress 5 alpha-reductase and to ensure similar activity with finasteride. CONSTITUTION: A method for preparing a composition containing dieckol for preventing alopecia or promoting hair growth comprises: a step of adding saccharolytic enzyme to Ecklonia cava to prepare enzyme extrac(S100)t; a step of filtering and freeze-drying; and a step of extracting the enzyme extract with organic solvent. The saccharolytic enzyme is celluclast(S200). A composition for preventing alopecia or promoting hair growth contains dieckol.
Abstract translation: 目的：提供一种用于预防脱发或促进毛发生长的组合物以抑制5α-还原酶并确保与非那雄胺类似的活性。 构成：用于制备含有甲羟戊酸以防止脱发或促进毛发生长的组合物的方法包括：将蔗糖分解酶加入埃克氏杆菌来制备酶促提取物的步骤（S100）t; 过滤冷冻干燥步骤; 和用有机溶剂提取酶提取物的步骤。 蔗糖酶是celluclast（S200）。 用于预防脱发或促进毛发生长的组合物含有甲羟戊酸。
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公开(公告)号：KR100904759B1
公开(公告)日：2009-06-29
申请号：KR1020080111952
申请日：2008-11-12
Applicant: 아쿠아그린텍(주)
CPC classification number: A61K8/97 , A61K36/03 , A61K2236/19 , A61Q19/02 , Y10S514/844
Abstract: A cosmetic composition for skin whitening which contains an Ecklonia cava extract is provided to ensure excellent whitening effect by using fluro tannin based polyphenol-containing extract. A method for manufacturing a cosmetic composition of skin whitening which contains an Ecklonia cava extract comprises: a step of adding saccharolytic enzyme to an ecklonia cava to extract the Ecklonia cava; a step of removing and filtering residue and freeze-drying the enzyme extract; and a step of extracting the extract with organic solvent. The method further comprises: a step of eluting in diethylether through a column filled with cellite to fraction an active ingredient; and a step of eluting with chloroform and methanol in a ratio of 2:1-0:1 through a column filled with sephadex to fraction the active ingredient.
Abstract translation: 提供含有Ecklonia cava提取物的用于皮肤美白的化妆品组合物，以通过使用含有单宁鞣酸的多酚提取物来确保优异的美白效果。 含有Ecklonia Cava提取物的皮肤美白化妆品组合物的制造方法包括：将蔗糖分解酶加入到ecklonia cava中以提取Ecklonia cava的步骤; 去除和过滤残留物并冷冻干燥酶提取物的步骤; 和用有机溶剂提取提取物的步骤。 该方法还包括：在乙醚中通过填充有细胞的柱分离活性成分的步骤; 和用氯仿和甲醇以2：1-0：1的比例通过填充有sephadex的柱洗脱以分离活性成分的步骤。
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