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公开(公告)号:WO2008157697A3
公开(公告)日:2009-03-26
申请号:PCT/US2008067508
申请日:2008-06-19
Applicant: MOMENTA PHARMACEUTICALS INC , D ALESSANDRO JOSEPHINE S , KISHIMOTO TAKASHI KEI , HEALY AILEEN
Inventor: D ALESSANDRO JOSEPHINE S , KISHIMOTO TAKASHI KEI , HEALY AILEEN
CPC classification number: C07K14/001 , G01N33/5008 , G01N2333/52
Abstract: The present invention provides methods and compositions for evaluating one or more properties of an amino acid copolymer.
Abstract translation: 本发明提供用于评估氨基酸共聚物的一种或多种性质的方法和组合物。
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2.MULTI-STEP METHOD FOR THE DIFFERENTIATION OF INSULIN POSITIVE, GLUCOSE 审中-公开
Title translation: 用于胰岛素阳性,葡萄糖分化的多步法公开(公告)号:WO2004011621A3
公开(公告)日:2004-07-08
申请号:PCT/US0323852
申请日:2003-07-29
Applicant: ES CELL INT PTE LTD , CLARKE DIANA , D ALESSANDRO JOSEPHINE S , LU KUANGHUI , WANG ANLAI
Inventor: CLARKE DIANA , D ALESSANDRO JOSEPHINE S , LU KUANGHUI , WANG ANLAI
IPC: A61K35/12 , A61K35/14 , A61K35/22 , A61K35/23 , A61K35/28 , A61K35/30 , A61K35/32 , A61K35/34 , A61K35/36 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/42 , A61K35/54 , A61P1/18 , A61P3/10 , C12N5/074 , C12N5/00 , C12N5/08 , C12N5/16
CPC classification number: C12N5/0678 , A61K35/12 , C12N2500/34 , C12N2500/38 , C12N2500/60 , C12N2501/01 , C12N2501/119 , C12N2501/12 , C12N2501/16 , C12N2501/175 , C12N2501/33 , C12N2501/335 , C12N2501/355 , C12N2501/39 , C12N2501/41 , C12N2501/835 , C12N2501/91
Abstract: The present invention provides improved methods of differentiating insulin+, glucose responsive islet-like structures from insulin- cells. The invention further provides methods for using insulin+, glucose responsive islet-like structures, as well as the insulin+, glucose responsive cells which comprise said islet-like clusters.
Abstract translation: 本发明提供了从胰岛素 - 细胞分化胰岛素+,葡萄糖反应性胰岛样结构的改进方法。 本发明还提供了使用胰岛素+,葡萄糖反应性胰岛样结构以及包含所述胰岛样簇的胰岛素+葡萄糖应答细胞的方法。
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