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公开(公告)号：WO2006071118A2
公开(公告)日：2006-07-06
申请号：PCT/NL2005050094
申请日：2005-12-23
Applicant: STICHTING TECH WETENSCHAPP , UNIV LEIDEN , RAM ARTHUR FRANCISCUS JOHANNES , DAMVELD ROBBERT ANTONIUS , ARENTSHORST MARK , VAN KUYK PATRICIA ANN , VAN DEN HONDEL CORNELIS ANTONI
Inventor： RAM ARTHUR FRANCISCUS JOHANNES , DAMVELD ROBBERT ANTONIUS , ARENTSHORST MARK , VAN KUYK PATRICIA ANN , VAN DEN HONDEL CORNELIS ANTONI
CPC classification number: C12Q1/18 , G01N2333/37
Abstract: The present invention relates to a fungus which produces substantially no functional protein with regulating activity on the transcription of genes which are involved in cell wall stress response. It also relates to a method for screening for antifungal agents, in particular to antifungal agents which target the cell wall. It also relates to a kit for screening for antifungal agents which disturb cell wall biogenesis.
Abstract translation: 本发明涉及一种真菌，其基本上不产生对参与细胞壁应激反应的基因的转录具有调节活性的功能性蛋白质。 它还涉及用于筛选抗真菌剂的方法，特别是靶向细胞壁的抗真菌剂。 它还涉及用于筛选干扰细胞壁生物发生的抗真菌剂的试剂盒。
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公开(公告)号：WO2006071118A3
公开(公告)日：2006-07-06
申请号：PCT/NL2005/050094
申请日：2005-12-23
Applicant: STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN , UNIVERSITEIT LEIDEN , RAM, Arthur, Franciscus, Johannes , DAMVELD, Robbert, Antonius , ARENTSHORST, Mark , VAN KUYK, Patricia, Ann , VAN DEN HONDEL, Cornelis, Antonius, Maria, Jacobus, Johannes
Inventor： RAM, Arthur, Franciscus, Johannes , DAMVELD, Robbert, Antonius , ARENTSHORST, Mark , VAN KUYK, Patricia, Ann , VAN DEN HONDEL, Cornelis, Antonius, Maria, Jacobus, Johannes
Abstract: The present invention relates to a fungus which produces substantially no functional protein with regulating activity on the transcription of genes which are involved in cell wall stress response. It also relates to a method for screening for antifungal agents, in particular to antifungal agents which target the cell wall. It also relates to a kit for screening for antifungal agents which disturb cell wall biogenesis.
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