公开(公告)号：WO2013190509A3

公开(公告)日：2013-12-27

申请号：PCT/IB2013/055096

申请日：2013-06-21

Applicant: DR.REDDYS LABORATORIES LIMITED

Inventor： NARIYAM, Sekhar Munaswamy ,  BHALERAO, Dinesh Shivaji ,  DAHANUKAR, Vilas Hareshwar ,  ORUGANTI, Srinivas ,  RAPOLU, Rajesh Kumar ,  KANDAGATLA, Bhaskar ,  IQBAL, Javed ,  KHOBARE, Sandip Ramdas ,  KALLAM, Srinivasa Reddy ,  BANDA, Malavika ,  GARARE, Vikas Sadashiv ,  EDA, Vishnuvardhana vema Reddy

IPC: C07C273/18 ,  C07C275/16 ,  C07D209/52 ,  C07K5/08 ,  A61K31/401 ,  A61P31/00

Abstract: Processes for preparing intermediates of Boceprevir and their use in preparation of Boceprevir or its pharmaceutically acceptable salts are provided.

公开(公告)号：WO2013118058A1

公开(公告)日：2013-08-15

申请号：PCT/IB2013/050976

申请日：2013-02-06

Applicant: DR.REDDYS LABORATORIES LIMITED

Inventor： JACKSON, Mark P

IPC: C07C405/00 ,  C07C59/68

CPC classification number: C07C67/475 ,  C07C69/732 ,  C07C69/736 ,  C07C211/03 ,  C07C211/04 ,  C07C211/05 ,  C07C211/06 ,  C07C211/07 ,  C07C211/09 ,  C07C211/11 ,  C07C211/27 ,  C07C211/35 ,  C07C405/00 ,  C07C2601/08 ,  C07C2601/14 ,  C07D295/027 ,  C07D311/94

Abstract: The present application relates to amine salts of prostaglandin analogs and their uses for the preparation of substantially pure prostaglandin analogs. Specific embodiments relate to amine salts of tafluprost and their uses for the preparation of substantially pure tafluprost.

Abstract translation: 本申请涉及前列腺素类似物的胺盐及其用于制备基本上纯的前列腺素类似物的用途。 具体实施方案涉及他氟前列素的胺盐及其用于制备基本上纯的他氟前列素的用途。

公开(公告)号：WO2013008250A2

公开(公告)日：2013-01-17

申请号：PCT/IN2012/000468

申请日：2012-07-02

Applicant: DR.REDDYS LABORATORIES LIMITED. ,  PEDDY, Vishweshwar ,  BOGE, Rajesham ,  CHIMALA, Venkata Ramana Reddy ,  MUDAPAKA, Vamsi Krishna ,  PATHIVADA, Deepika ,  NALIVELA, Venu ,  KUMAR, Ramya ,  RAMAKRISHNAN, Srividya ,  RANGINENI, Srinivasulu ,  SAMINENI, Laxmi Charan

Inventor： PEDDY, Vishweshwar ,  BOGE, Rajesham ,  CHIMALA, Venkata Ramana Reddy ,  MUDAPAKA, Vamsi Krishna ,  PATHIVADA, Deepika ,  NALIVELA, Venu ,  KUMAR, Ramya ,  RAMAKRISHNAN, Srividya ,  RANGINENI, Srinivasulu ,  SAMINENI, Laxmi Charan

CPC classification number: C07C271/28 ,  A61K31/325

Abstract: Aspects of the present invention relate to crystalline form of retigabine, process for its preparation and processes for preparation of mixture of known retigabine modifications and pharmaceutical composition comprising thereof.

Abstract translation: 本发明的方面涉及瑞替加林的结晶形式，其制备方法以及制备已知的瑞替加滨改性物的混合物的方法以及包含其的药物组合物。

公开(公告)号：WO2015107444A1

公开(公告)日：2015-07-23

申请号：PCT/IB2015/050212

申请日：2015-01-12

Applicant: DR.REDDYS LABORATORIES LIMITED

Inventor： MEDISETTY, Rajesh ,  VENUGOPAL, Palanati ,  CHOUHAN, Vishaldeep

IPC: G01N33/53 ,  G01N33/541

CPC classification number: G01N33/68 ,  G01N2333/4716 ,  G01N2333/70596

Abstract: The present invention discloses an in-vitro bioassay for distinguishing post translationally modified isoforms of a protein. In particular, the present invention discloses an in-vitro method for distinguishing post translationally modified isoforms of an antibody by C1q based ELISA involving a metal ion chelator.

Abstract translation: 本发明公开了用于区分蛋白质翻译后修饰的同工型的体外生物测定法。 特别地，本发明公开了一种通过涉及金属离子螯合剂的基于C1q的ELISA区分抗体的翻译后修饰同种型的体外方法。

公开(公告)号：WO2013168126A1

公开(公告)日：2013-11-14

申请号：PCT/IB2013/053785

申请日：2013-05-10

Applicant: DR.REDDYS LABORATORIES LIMITED

Inventor： IQBAL, Javed ,  ORUGANTI, Srinivas ,  RAPOLU, Rajesh Kumar ,  PEDDY, Vishweshwar ,  BOGE, Rajesham ,  PATHIVADA, Deepika ,  VELAGA, Dharma Jagannadha Rao ,  YARRAGUNTLA, Sesha Reddy ,  BADDAM, Sudhakar Reddy ,  NAREDLA, Anitha ,  DONIPARTHI, Kiran Kumar ,  NADGOUD, Ramesh Kumar ,  PAGADALA, Narasimha Rao ,  UNNIARAN, Syam Kumar ,  RAMAKRISHNAN, Srividya

IPC: C07D405/14 ,  A61K31/404 ,  A61P25/24

CPC classification number: C07D405/12 ,  C07B2200/13 ,  C07D405/14

Abstract: Provided are crystalline and amorphous vilazodone hydrochloride. Further provided are amorphous solid dispersions of vilazodone hydrochloride with pharmaceutically acceptable carries. Also provided is a process for the preparation of form I of vilazodone free base.

Abstract translation: 提供结晶和无定形的维拉唑酮盐酸盐。 还提供了盐酸维拉扎酮与药学上可接受的载体的无定形固体分散体。 还提供了制备维拉唑酮游离碱形式I的方法。