公开(公告)号：WO2013081700A1

公开(公告)日：2013-06-06

申请号：PCT/US2012/053515

申请日：2012-08-31

Applicant: CODEXIS, INC. ,  ALVIZO, Oscar ,  MESHULAM-SIMON, Galit ,  LUM, Amy ,  SARAN, Dayal

Inventor： ALVIZO, Oscar ,  MESHULAM-SIMON, Galit ,  LUM, Amy ,  SARAN, Dayal

IPC: C12N1/19 ,  C12N15/81 ,  C12P7/06

CPC classification number: C12P7/04 ,  C12N15/81 ,  C12N15/815 ,  C12P7/10 ,  Y02E50/16 ,  Y02E50/17

Abstract: The invention relates to recombinant yeast host cells that overexpress proteins to improve glucose utilization, pentose sugar utiltization and/or production of a fermentation product in a fermentation reaction.

Abstract translation: 本发明涉及在发酵反应中过表达蛋白质以改善葡萄糖利用率，戊糖糖利用和/或产生发酵产物的重组酵母宿主细胞。

公开(公告)号：WO2011123576A3

公开(公告)日：2011-12-22

申请号：PCT/US2011030606

申请日：2011-03-30

Applicant: CODEXIS INC ,  MCDANIEL ROBERT ,  MESHULAM-SIMON GALIT ,  ALVIZO OSCAR ,  ZHANG XIYUN

Inventor： MCDANIEL ROBERT ,  MESHULAM-SIMON GALIT ,  ALVIZO OSCAR ,  ZHANG XIYUN

IPC: C12P5/00 ,  C12P1/00 ,  C12P15/00

CPC classification number: C12P5/007 ,  C12N9/1085 ,  C12N9/88

Abstract: The present invention relates to methods for producing monoterpenes, particularly tricyclene, by culturing microbial organisms that express a terpene synthase and optionally a prenyl transferase.

Abstract translation: 本发明涉及通过培养表达萜烯合酶和任选的异戊二烯基转移酶的微生物生物来生产单萜，特别是三环烯的方法。

公开(公告)号：WO2006017576A2

公开(公告)日：2006-02-16

申请号：PCT/US2005/027565

申请日：2005-08-02

Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY ,  SPORMANN, Alfred M. ,  MULLER, Jochen A. ,  ROSNER, Bettina M. ,  VON ABENDROTH, Gregory ,  MESHULAM-SIMON, Galit ,  MCCARTY, Perry L.

Inventor： SPORMANN, Alfred M. ,  MULLER, Jochen A. ,  ROSNER, Bettina M. ,  VON ABENDROTH, Gregory ,  MESHULAM-SIMON, Galit ,  MCCARTY, Perry L.

IPC: C12N1/21

CPC classification number: C12N1/30 ,  B09C1/002 ,  C12N9/0004

Abstract: Compositions and methods are provided that relate to the bioremediation of chlorinated ethenes, particularly the bioremediation of vinyl chloride by Dehalococcoides -like organisms. An isolated strain of bacteria, Dehalococcoides sp. strain VS, that metabolizes vinyl chloride is provided; the genetic sequence of the enzyme responsible for vinyl chloride dehalogenation; methods of assessing the capability of endogenous organisms at an environmental site to metabolize vinyl chloride; and a method of using the strains of the invention for bioremediation.

Abstract translation: 提供了组合物和方法，其涉及氯代乙炔的生物修复，特别是由脱卤胆酸类生物体对氯乙烯的生物修复。 分离菌株，Dehalococcoides sp。 提供代谢氯乙烯的菌株VS; 负责氯乙烯脱卤的酶的基因序列; 评估环境部位内源生物体代谢氯乙烯能力的方法; 以及使用本发明的菌株进行生物修复的方法。

公开(公告)号：IL127943A

公开(公告)日：2010-12-30

申请号：IL12794399

申请日：1999-01-07

Applicant: MAGDASSI SHLOMO ,  EFRON DOV ,  MAOR ZEEV ,  AHAVA DEAD SEA LAB LTD ,  GAVERIELI JONAH ,  SHAUL YEHUDA ,  MESHULAM-SIMON GALIT ,  GILAD ZIVA

Inventor： MAGDASSI SHLOMO ,  EFRON DOV ,  MAOR ZEEV ,  GAVERIELI JONAH ,  SHAUL YEHUDA ,  MESHULAM-SIMON GALIT ,  GILAD ZIVA

IPC: A61K8/27 ,  A61K8/49 ,  A61K8/67 ,  A61K8/96 ,  A61K9/06 ,  A61K35/02 ,  A61P17/00 ,  A61Q17/00 ,  A61Q19/00

Abstract: The preset invention relates to a pharmaceutical cream composition for topical application for the treatment of skin disorders and skin diseases, comprising 1-6 wt. % Dead Sea Mud as an active ingredient. Said composition is for use in treating skin disorders and skin diseases such as psoriasis, saborrehic dermatitis, xerosis, attopic dermatitis, eczema, diaper rush, skin burns of stage I and sensitive skin. Said cream composition is also for use as a leave-on cosmetic cream for beautifying and enhancing the skin appearance. In addition to Dead Sea Mud said composition comprises ingredients suitable for the preparation of cosmetic cream. Said cream can further comprises up to 4 wt % Dead Sea water.

公开(公告)号：WO2011123576A2

公开(公告)日：2011-10-06

申请号：PCT/US2011/030606

申请日：2011-03-30

Applicant: CODEXIS, INC. ,  MCDANIEL, Robert ,  MESHULAM-SIMON, Galit ,  ALVIZO, Oscar ,  ZHANG, Xiyun

Inventor： MCDANIEL, Robert ,  MESHULAM-SIMON, Galit ,  ALVIZO, Oscar ,  ZHANG, Xiyun

IPC: C12P5/00

CPC classification number: C12P5/007 ,  C12N9/1085 ,  C12N9/88

Abstract: The present invention relates to methods for producing monoterpenes, particularly tricyclene, by culturing microbial organisms that express a terpene synthase and optionally a prenyl transferase.

Abstract translation: 本发明涉及通过培养表达萜烯合酶和任选的异戊二烯基转移酶的微生物生产单萜，特别是三环烯的方法。

公开(公告)号：WO2006017576A3

公开(公告)日：2006-06-01

申请号：PCT/US2005027565

申请日：2005-08-02

Applicant: UNIV LELAND STANFORD JUNIOR ,  SPORMANN ALFRED M ,  MULLER JOCHEN A ,  ROSNER BETTINA M ,  VON ABENDROTH GREGORY ,  MESHULAM-SIMON GALIT ,  MCCARTY PERRY L

Inventor： SPORMANN ALFRED M ,  MULLER JOCHEN A ,  ROSNER BETTINA M ,  VON ABENDROTH GREGORY ,  MESHULAM-SIMON GALIT ,  MCCARTY PERRY L

IPC: C12N1/12 ,  A01N63/00

CPC classification number: C12N1/30 ,  B09C1/002 ,  C12N9/0004

Abstract: Compositions and methods are provided that relate to the bioremediation of chlorinated ethenes, particularly the bioremediation of vinyl chloride by Dehalococcoides-like organisms. An isolated strain of bacteria, Dehalococcoides sp. strain VS, that metabolizes vinyl chloride is provided; the genetic sequence of the enzyme responsible for vinyl chloride dehalogenation; methods of assessing the capability of endogenous organisms at an environmental site to metabolize vinyl chloride; and a method of using the strains of the invention for bioremediation.

Abstract translation: 提供了涉及氯化乙烯的生物修复，特别是类Dehalococcoides生物体对氯乙烯的生物修复的组合物和方法。 一种分离的细菌菌株Dehalococcoides sp。 提供代谢氯乙烯的菌株VS; 负责氯乙烯脱卤作用的酶的基因序列; 评估环境部位内源性有机体代谢氯乙烯能力的方法; 以及使用本发明的菌株进行生物修复的方法。