公开(公告)号：US20220307870A1

公开(公告)日：2022-09-29

申请号：US17703014

申请日：2022-03-24

Applicant: Giuliani S.R.L ,  OPTOELETTRONICA ITALIA S.R.L.

Inventor： Alfredo MAGLIONE ,  Nicola BATTISTI

IPC: G01D5/347

Abstract: Position sensor for a mechanical device, including: an optical emitter arranged for projecting an incident radiation on a positioning track of the mechanical device provided with multiple optical sections; an optical detector arranged for detecting a reflected radiation coming from the positioning track and for generating a corresponding measurement signal; an electronic processing unit arranged for calculating, on the basis of such measurement signal, a reflectance value indicative of the reflectivity of the zone of the positioning track hit by the incident ray so as to distinguish the different optical sections of the positioning track. The position sensor also comprises a signaling module arranged for sending a warning signal as a function of the reflectance value, in order to provide to the user indications relative to the level of deterioration of the optical sections of the positioning track.

公开(公告)号：US20160108471A1

公开(公告)日：2016-04-21

申请号：US14894634

申请日：2014-04-17

Applicant: OPTOELETTRONICA ITALIA S.R.L.

Inventor： Alfredo MAGLIONE ,  Cristina RESS

IPC: C12Q1/68 ,  G01N21/63 ,  G01N21/77

CPC classification number: C12Q1/6876 ,  C12Q1/6825 ,  C12Q2600/178 ,  G01N21/63 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/77 ,  G01N2201/022 ,  G01N2201/062 ,  G01N2201/0633

Abstract: A kit for detecting a micro-RNA of interest in at least one sample (C) extracted from a body fluid, including: at least one device (2) including a housing casing (2a) in which at least one housing seat (2b) is obtained for said at least one sample (C), and at least one opening (2c) through which said housing seat (2b) is accessible from the outside; at least one container means (3) for said at least one sample (C), said at least one container means (3) being insertable/disconnectable in/from said housing seat (2b) through said at least one opening (2c); at least one optical excitation group (5), housed in said housing casing (2a), designed to emit at least one excitation light radiation (λ,λ1) towards said at least one housing seat (2b); at least one detection group (6), designed to detect at least one emission light radiation (λ2), that can be generated, in use, by said at least one sample (C), said at least one sample (C) being optically excitable by said at least one excitation light radiation (λ, λ1) emitted by said at least one optical excitation group (5), said at least one detection group (6) being designed to supply at least one electric output signal (SO-signal output) correlated with the quantity, in said at least one sample (C), of said micro-RNA of interest; at least one processing unit (7) designed to receive and process said at least one electric signal (SO) and to output an index correlated with the quantity of said micro-RNA of interest in said at least one sample (C); said at least one container means (3) being made of a material permeable to said at least one excitation light radiation (λ, λ1) and to said at least one emission light radiation (λ2); said at least one group (6) for detecting said emission light radiation (λ2) comprises at least one sensor means (6a) of silicon photomultiplier type.

公开(公告)号：US11754422B2

公开(公告)日：2023-09-12

申请号：US17703014

申请日：2022-03-24

Applicant: Giuliani S.R.L ,  OPTOELETTRONICA ITALIA S.R.L.

Inventor： Alfredo Maglione ,  Nicola Battisti

IPC: G01D5/347 ,  G01D3/08

CPC classification number: G01D5/34746 ,  G01D5/347 ,  G01D3/08

Abstract: Position sensor for a mechanical device, including: an optical emitter arranged for projecting an incident radiation on a positioning track of the mechanical device provided with multiple optical sections; an optical detector arranged for detecting a reflected radiation coming from the positioning track and for generating a corresponding measurement signal; an electronic processing unit arranged for calculating, on the basis of such measurement signal, a reflectance value indicative of the reflectivity of the zone of the positioning track hit by the incident ray so as to distinguish the different optical sections of the positioning track. The position sensor also comprises a signaling module arranged for sending a warning signal as a function of the reflectance value, in order to provide to the user indications relative to the level of deterioration of the optical sections of the positioning track.

公开(公告)号：US10663323B2

公开(公告)日：2020-05-26

申请号：US15925788

申请日：2018-03-20

Applicant: GIULIANI S.R.L. ,  OPTOELETTRONICA ITALIA S.R.L.

Inventor： Nicola Battisti ,  Alfredo Maglione

IPC: G01D5/347 ,  G01D5/245

Abstract: System for measuring the position of a mechanical member, which comprises an optical detection system and a positioning track arranged on two mechanical members of a mechanical device. The positioning track is provided with a succession of multiple sectors, each of which comprises a first delimitation section and a second delimitation section spaced from each other, and a first identification section and a second identification section which are provided with a different optical contrast with respect to the first delimitation section and to the second delimitation section. In each sector, the first identification section is delimited between the first delimitation section and the second delimitation section. In addition, the length of the identification sections of each sector is different from the length of the identification sections of each other sector of the succession, so as to unequivocally identify the corresponding sector.

公开(公告)号：US20180266853A1

公开(公告)日：2018-09-20

申请号：US15925788

申请日：2018-03-20

Applicant: Giuliani S.R.L. ,  Optoelettronica Italia S.R.L.

Inventor： Nicola Battisti ,  Alfredo Maglione

IPC: G01D5/347

CPC classification number: G01D5/34746 ,  G01D5/2455 ,  G01D5/3473 ,  G01D5/34784

Abstract: System for measuring the position of a mechanical member, which comprises an optical detection system and a positioning track arranged on two mechanical members of a mechanical device. The positioning track is provided with a succession of multiple sectors, each of which comprises a first delimitation section and a second delimitation section spaced from each other, and a first identification section and a second identification section which are provided with a different optical contrast with respect to the first delimitation section and to the second delimitation section. In each sector, the first identification section is delimited between the first delimitation section and the second delimitation section. In addition, the length of the identification sections of each sector is different from the length of the identification sections of each other sector of the succession, so as to unequivocally identify the corresponding sector.

公开(公告)号：WO2014191850A1

公开(公告)日：2014-12-04

申请号：PCT/IB2014/060793

申请日：2014-04-17

Applicant: OPTOELETTRONICA ITALIA S.R.L

Inventor： MAGLIONE, Alfredo ,  RESS, Cristina

IPC: G01N21/64

CPC classification number: C12Q1/6876 ,  C12Q1/6825 ,  C12Q2600/178 ,  G01N21/63 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/77 ,  G01N2201/022 ,  G01N2201/062 ,  G01N2201/0633

Abstract: It's disclosed a kit for detecting a micro-RNA of interest in at least one sample (C) extracted from a body fluid, comprising: at least one device (2) including a housing casing (2a) in which at least one housing seat (2b) is obtained for said at least one sample (C), and at least one opening (2c) through which said housing seat (2b) is accessible from the outside; at least one container means (3) for said at least one sample (C), said at least one container means (3) being insertable/disconnectable in/from said housing seat (2b) through said at least one opening (2c); at least one optical excitation group (5), housed in said housing casing (2a), designed to emit at least one excitation light radiation (λ, λ1 ) towards said at least one housing seat (2b); at least one detection group (6), designed to detect at least one emission light radiation (λ2), that can be generated, in use, by said at least one sample (C), said at least one sample (C) being optically excitable by said at least one excitation light radiation (λ, λ1) emitted by said at least one optical excitation group (5), said at least one detection group (6) being designed to supply at least one electric output signal (SO- signal output) correlated with the quantity, in said at least one sample (C), of said micro-RNA of interest; at least one processing unit (7) designed to receive and process said at least one electric signal (SO) and to output an index correlated with the quantity of said micro-RNA of interest in said at least one sample (C); said at least one container means (3) being made of a material permeable to said at least one excitation light radiation (λ, λ1) and to said at least one emission light radiation (A2); said at least one group (6) for detecting said emission light radiation (A2) comprises at least one sensor means (6a) of silicon photomultiplier type.

Abstract translation: 公开了用于检测从体液中提取的至少一个样品（C）中感兴趣的微RNA的试剂盒，其包括：至少一个装置（2），其包括壳体壳体（2a），其中至少一个壳体座 获得所述至少一个样品（C）的至少一个开口（2c），以及至少一个开口（2c），所述壳体座（2b）可以从外部进入; 用于所述至少一个样品（C）的至少一个容器装置（3），所述至少一个容器装置（3）可通过所述至少一个开口（2c）从所述壳体座（2b）插入/断开; 容纳在所述壳体壳体（2a）中的至少一个光学激发组（5）被设计成朝向所述至少一个壳体座（2b）发射至少一个激发光辐射（λ，λ1）; 至少一个检测组（6），被设计成检测在所述至少一个样品（C）中可以在使用中产生的至少一个发射光辐射（λ2），所述至少一个样品（C）是光学的 由所述至少一个光学激发组（5）发射的所述至少一个激发光辐射（λ，λ1）激发，所述至少一个检测组（6）被设计成提供至少一个电输出信号（SO-信号 输出）与所述至少一个样品（C）中所述感兴趣的微RNA的量相关; 至少一个处理单元（7）被设计为接收和处理所述至少一个电信号（SO）并输出与所述至少一个样品（C）中的所述感兴趣的微RNA的量相关的指数; 所述至少一个容器装置（3）由可透过所述至少一个激发光辐射（λ，λ1）和所述至少一个发射光辐射（A2）的材料制成; 所述至少一个用于检测所述发射光辐射的组（6）包括至少一个硅光电倍增器类型的传感器装置（6a）。

公开(公告)号：WO2007121971A1

公开(公告)日：2007-11-01

申请号：PCT/EP2007/003547

申请日：2007-04-23

Applicant: OPTOELETTRONICA ITALIA S.R.L. ,  MOLON, Sergio ,  MAGLIONE, Alfredo

Inventor： MOLON, Sergio ,  MAGLIONE, Alfredo

IPC: F24J2/06 ,  G02B7/182 ,  H01L31/0232 ,  G02B17/06

CPC classification number: G02B19/0023 ,  F24S23/71 ,  F24S25/40 ,  F24S25/632 ,  F24S2023/872 ,  F24S2025/6007 ,  G02B7/183 ,  G02B19/0042 ,  Y02E10/42 ,  Y02E10/47

Abstract: A radiation concentrating device, comprising a substantially parabolic mirror (11), which is adapted to reflect the energy radiation or electromagnetic radiation (12) that reaches it so as to converge toward an active area (13) of a receiving element (14) arranged in front, the active area being interposed between the focal point of the mirror (11) and the mirror (11) itself, the mirror (11) and the receiving element (14) being fixed by way of coupling means to a same base (15). The transverse dimension (A) of the active area (13) is smaller than the transverse dimension (B) of the mirror (11) arranged in front. The base (115) is preset to support a plurality of parabolic mirrors (111) and corresponding receiving elements (114), which are mutually connected by means of conductors (116).

Abstract translation: 一种辐射聚集装置，包括基本上抛物面的反射镜（11），其适于反射到达其的能量辐射或电磁辐射（12），以朝向被布置的接收元件（14）的有源区域（13）会聚。 在前面，有源区被插入在反射镜（11）的焦点和反射镜（11）本身之间，反射镜（11）和接收元件（14）通过耦合装置固定到相同的基座（ 15）。 有源区域（13）的横向尺寸（A）小于布置在前面的反射镜（11）的横向尺寸（B）。 基座（115）被预设为支撑多个抛物面镜（111）和相应的接收元件（114），它们通过导体（116）相互连接。

公开(公告)号：EP3379207A1

公开(公告)日：2018-09-26

申请号：EP18162678.9

申请日：2018-03-19

Applicant: Giuliani S.r.l. ,  Optoelettronica Italia S.R.L.

Inventor： BATTISTI, Nicola ,  MAGLIONE, Alfredo

IPC: G01D5/347 ,  G01D5/245

Abstract: System for measuring the position of a mechanical member, which comprises optical detection means (2) intended to be arranged on a first mechanical member (101), and a positioning track (3) intended to be arranged on a second mechanical member (102) susceptible of relative motion with respect to the first mechanical member (101).
The positioning track (3) is provided with at least one succession (4) of multiple sectors (5), and each of which comprises a first delimitation section (11) and a second delimitation section (12) spaced from each other, and a first identification section (13) and a second identification section (14) which are provided with a different optical contrast with respect to the first delimitation section (11) and to the second delimitation section (12).
In each said sector (5), the first identification section (13) is delimited between the first delimitation section (11) and the second delimitation section (12).
In addition, the length of the identification sections (13, 14) of each said sector (5) is different from the length of the identification sections (13, 14) of each other sector (5) of the succession (4), so as to unequivocally identify the corresponding sector (5).

公开(公告)号：EP2951537A2

公开(公告)日：2015-12-09

申请号：EP14707228.4

申请日：2014-01-29

Applicant: Optoelettronica Italia S.R.L. ,  Giuliani S.r.l.

Inventor： Battisti, Nicola ,  Maglione, Alfredo

IPC: G01D5/244 ,  G01D18/00

CPC classification number: G01D5/12 ,  G01D5/2448 ,  G01D18/006

Abstract: A method for detecting the reciprocal position between a cylinder and a piston in a cylinder-piston unit, including the following phases: setup of a cylinder-piston unit featuring at least one tubular body (2) presenting at least one passing accommodation host (6); at least one moving body (5) which can be longitudinally shifted in such tubular body (2), featuring at least one reference area (5c) extending for a portion (5d) on the surface of such moving body (5); at least means of detection (7) which can be accommodated in such passing accommodation host (6), oriented towards such moving body (5) and meant to detect the presence or absence of such reference area (5c) at one of their detection area (7c), and to generate at least one corresponding output electrical signal (s7), as a response to the possible detection of such reference area (5c); at least one elaboration and program control unit (8), meant to receive as an input at least one of such output electrical signals (s7) and to generate as an output at least one electrical signal (s8) of detection; activation of such detection means (7) (phase 100); elaboration by at least one of such elaboration and program control units (8) of at least one of such signals (s7) which are the output of such detection means (7) (phase 200), with such elaboration phase including a comparison (phase 220) between at least one of such output electrical signals (s7) and the respective maximum and minimum reference thresholds (Smax, Smin); generation, based on such elaboration (phase 200), of a electrical signal of detection (s8) by at least one of such elaboration and program control units (8) (phase 300); such maximum and minimum reference thresholds (Smax, Smin) being periodically updated.

公开(公告)号：EP4279904A1

公开(公告)日：2023-11-22

申请号：EP23173727.1

申请日：2023-05-16

Applicant: Optoelettronica Italia S.R.L.

Inventor： MAGLIONE, Alfredo ,  DETASSIS, Simone ,  RESS, Cristina ,  LUTTERI, Marco

IPC: G01N21/64 ,  C12Q1/6818 ,  C12Q1/6825

Abstract: Device for detecting biomolecules, comprising a container (2) intended to be filled with a mixture comprising a biomolecule (30) to be detected, a reagent (4) bondable to the biomolecule (30) and susceptible of emitting a first light radiation (λ 1 ) in fluorescence or chemiluminescence, and a plurality of magnetic beads (41) chemically bondable to the biomolecule (30). The device comprises a first detector (71) for detecting the first light radiation (λ 1 ) for detecting the biomolecule (30) concentration (C), a first emitter (61) for emitting a second light radiation (λ 2 ) for irradiating the magnetic beads (41), and a second detector (72) for detecting a third light radiation (λ 3 ) consequently transmitted, reflected or emitted by the magnetic beads (41) for detecting the quantity of magnetic beads (41). The device also comprises a logic control unit (8) configured for calculating a correct concentration (C) value of biomolecule (30) on the basis of the above measurements of the light radiations (λ 1 , λ 3 ).