中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

15 records (took 0.027 seconds)

    COPY NUMBER VARIATION DETERMINATION, METHODS AND SYSTEMS
    3.
    发明申请
    COPY NUMBER VARIATION DETERMINATION, METHODS AND SYSTEMS 审中-公开
    复制数变化确定，方法和系统

    公开(公告)号：WO2009033178A1

    公开(公告)日：2009-03-12

    申请号：PCT/US2008/075636

    申请日：2008-09-08

    Applicant: FLUIDIGM CORPORATION ,  RAMAKRISHNAN, Ramesh

    Inventor： RAMAKRISHNAN, Ramesh

    IPC: G01N33/48

    CPC classification number: C12Q1/6869 ,  C12Q1/6851 ,  C12Q2545/101 ,  C12Q2527/143

    Abstract: The present invention methods and systems for determining copy number variation of a target polynucleotide in a genome of a subject including amplification based techniques. Methods can include pre-amplification of the sample followed by distribution of sample and a plurality of reaction volumes, quantitative detection of a target polynucleotide and a reference polynucleotide, and analysis so as to determine the relative copy number of the target polynucleotide sequence in the genome of the subject.

    Abstract translation: 用于确定受试者的基因组中的靶多核苷酸的拷贝数变异的本发明的方法和系统，包括基于扩增的技术。 方法可以包括样品的预扩增，随后分布样品和多个反应体积，定量检测靶多核苷酸和参考多核苷酸，并进行分析，以确定基因组中靶多核苷酸序列的相对拷贝数 的主题。

    METHOD AND APPARATUS FOR BIOLOGICAL SAMPLE ANALYSIS
    4.
    发明申请
    METHOD AND APPARATUS FOR BIOLOGICAL SAMPLE ANALYSIS 审中-公开
    生物样品分析方法与装置

    公开(公告)号：WO2008067552A2

    公开(公告)日：2008-06-05

    申请号：PCT/US2007/086146

    申请日：2007-11-30

    Applicant: FLUIDIGM CORPORATION ,  SUN, Gang ,  RAMAKRISHNAN, Ramesh ,  JONES, Robert C.

    Inventor： SUN, Gang ,  RAMAKRISHNAN, Ramesh ,  JONES, Robert C.

    IPC: G06T11/20

    CPC classification number: C12Q1/686 ,  C12Q2565/629 ,  C12Q2565/501 ,  C12Q2545/114

    Abstract: A method of adjusting amplification curves in a PCR experiment includes receiving a plurality of amplification curves for a sample and computing a first parameter for each of the plurality of amplification curves. The method also includes computing a second parameter for each of the plurality of amplification curves and computing a third parameter using at least a portion of the first or second parameters. The method further includes computing an offset for each of the plurality of amplification curves. The offset is a function of the first parameter and the third parameter. Moreover, the method includes adjusting at least one of the plurality of amplification curves by subtracting the offset.

    Abstract translation: 在PCR实验中调整扩增曲线的方法包括接收样品的多个放大曲线并计算多个放大曲线中的每一个的第一参数。 该方法还包括为多个放大曲线中的每一个计算第二参数，并使用第一或第二参数的至少一部分来计算第三参数。 该方法还包括计算多个放大曲线中的每一个的偏移量。 偏移量是第一个参数和第三个参数的函数。 此外，该方法包括通过减去偏移来调整多个放大曲线中的至少一个。

    ELECTRONIC NAVIGATION SYSTEM AND METHOD
    10.
    发明申请
    ELECTRONIC NAVIGATION SYSTEM AND METHOD 审中-公开
    电子导航系统和方法

    公开(公告)号：WO1996000373A1

    公开(公告)日：1996-01-04

    申请号：PCT/US1995007859

    申请日：1995-06-23

    Applicant: SHIELDS ENTERPRISES, INC. ,  BEHR, David, A. ,  RAMAKRISHNAN, Ramesh

    Inventor： SHIELDS ENTERPRISES, INC.

    IPC: G01C21/20

    CPC classification number: G08G1/096811 ,  G01C21/26 ,  G01C21/32 ,  G01C21/3626 ,  G01C21/3679 ,  G08G1/096716 ,  G08G1/096741 ,  G08G1/096775 ,  G08G1/096816 ,  G08G1/096822 ,  G08G1/096838 ,  G08G1/096844 ,  G08G1/096861 ,  G08G1/096872 ,  G08G1/096883 ,  G08G1/096894

    Abstract: The invention provides a method and system for providing route guidance and other information from a base unit (12) to a remote unit (16, 18, 20) in response to a request from the remote unit. A query (120) is formatted at the remote unit, the query including the request, and is transmitted from the remote unit to the base unit. Requested route guidance information is calculated at the base unit in response to the query, using a large up-to-date database (72) located at the base unit. A response (160) to the query is formatted at the base unit, the response including route guidance information. The response is then transmitted from the base unit to the remote unit for display. The transmission is made in a compact form through the use of maneuver arms (figs. 6 to 10) and combined maneuver arms (fig. 39) and through the use of tokenized forms (fig. 40). A maneuver arm represents a road at an intersection, for depiction on a display, by one or two endpoint coordinates. The tokenized forms are expanded at the remote unit into textual driving instructions for each of one or more languages. In addition, the amount of information available at a remote unit can be increased by providing the remote unit with information from the base unit which is not adequately covered by any databases on-board the remote unit.

    Abstract translation: 本发明提供一种方法和系统，用于响应于来自远程单元的请求，从基本单元（12）向远程单元（16,18,20）提供路线引导和其他信息。 查询（120）在远程单元格式化，查询包括请求，并从远程单元发送到基本单元。 响应于查询，使用位于基本单元的大型最新数据库（72），在基本单元处计算请求的路线引导信息。 查询的响应（160）在基本单元格式化，响应包括路线引导信息。 然后响应从基本单元发送到远程单元以进行显示。 通过使用机动臂（图6至10）和组合的机动臂（图39）和通过使用标记形式（图40），可以使紧凑形式进行变速器。 机动臂代表交叉路口的一条道路，用于在显示器上描绘一个或两个端点坐标。 令牌化形式在远程单元扩展为一种或多种语言中的每一种的文本驾驶指令。 此外，通过向远程单元提供来自基站单元的信息，远程单元可用的信息量可以通过远程单元上的任何数据库没有充分覆盖的信息来增加。

Patent Agency Ranking