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    METHOD AND APPARATUS FOR RAPID SEQUENTIAL FLOW INJECTION
    3.
    发明专利
    METHOD AND APPARATUS FOR RAPID SEQUENTIAL FLOW INJECTION 未知

    公开(公告)号：SG11201700972VA

    公开(公告)日：2017-03-30

    申请号：SG11201700972V

    申请日：2015-08-13

    Applicant: SENSIQ TECHNOLOGIES INC

    Inventor： STRANDE CHRISTOPHER IVER

    IPC: G01N35/10

    Abstract: A fluid delivery system and process for fluid delivery is provided that is useful in in flow-injection based sensing measurements, wherein samples from a sample rack are introduced into a flow cell where sensing measurements are taken. The system and process utilize at least two holding lines where each holding line can retain one of the samples prior to injection of the thus retained sample into a flow cell. The introduction of the samples from the sample racks to the holding lines is alternated and the injection of the samples from the holding lines to the flow cell are alternated so that one holding line is loaded with one of the samples simultaneously with another sample being injected from the another holding line to the flow cell.

    METHOD AND APPARATUS FOR RAPID SEQUENTIAL FLOW INJECTION
    4.
    发明申请
    METHOD AND APPARATUS FOR RAPID SEQUENTIAL FLOW INJECTION 审中-公开

    公开(公告)号：US20170234902A1

    公开(公告)日：2017-08-17

    申请号：US15502846

    申请日：2015-08-13

    Applicant: SENSIQ TECHNOLOGIES, INC.

    Inventor： Christopher Iver Strande

    IPC: G01N35/10 ,  G01N21/11 ,  G01N21/552

    Abstract: A fluid delivery system and process for fluid delivery is provided that is useful in in flow-injection based sensing measurements, wherein samples from a sample rack are introduced into a flow cell where sensing measurements are taken. The system and process utilize at least two holding lines where each holding line can retain one of the samples prior to injection of the thus retained sample into a flow cell. The introduction of the samples from the sample racks to the holding lines is alternated and the injection of the samples from the holding lines to the flow cell are alternated so that one holding line is loaded with one of the samples simultaneously with another sample being injected from the another holding line to the flow cell.

    Label-free biomolecular interaction analysis using a rapid analyte dispersion injection method
    6.
    发明授权
    Label-free biomolecular interaction analysis using a rapid analyte dispersion injection method 有权

    公开(公告)号：US09990464B1

    公开(公告)日：2018-06-05

    申请号：US14049863

    申请日：2013-10-09

    Applicant: SENSIQ TECHNOLOGIES, INC.

    Inventor： John Gerard Quinn

    IPC: C12M1/34 ,  G06F19/12 ,  G01N33/557 ,  G01N35/08 ,  G01N33/53 ,  G01N21/55 ,  G01N21/552 ,  G01N35/10 ,  G01N21/05

    CPC classification number: G06F19/12 ,  B01L2300/0636 ,  G01N21/272 ,  G01N21/55 ,  G01N21/553 ,  G01N33/53 ,  G01N35/08 ,  G01N35/085 ,  G01N35/1097 ,  G01N2021/058 ,  G01N2035/00702

    Abstract: Dispersion injection methods for determining biomolecular interaction parameters in label-free biosensing systems are provided. The methods generally relate to the use of a single analyte injection that generates a smoothly-varying concentration gradient via dispersion en route to a sensing region possessing an immobilized binding partner. The present method incorporates the use of an internal standard which provides a reference as to the dispersion conditions present which can then be used to calculate an effective diffusion coefficient for the analyte of interest based on a universal calibration function. The effective diffusion coefficient can then be incorporated into the appropriate dispersion model to provide a calibrated dispersion model. The calibrated dispersion model can then be incorporated into the desired interaction model to provide a reliable representation of the analyte concentration at the sensing region at any time during the injection. The use of the internal standard and universal calibration function permit use of a wide range of injection conditions which may not otherwise be consistent with a particular dispersion model. Thus, the present methods allow for higher flow rates and lower sample volumes thereby increasing assay speed and decreasing sample consumption.

    METHOD AND APPARATUS FOR RAPID SEQUENTIAL FLOW INJECTION
    7.
    发明申请
    METHOD AND APPARATUS FOR RAPID SEQUENTIAL FLOW INJECTION 审中-公开
    用于快速顺序流注射的方法和装置

    公开(公告)号：WO2016025738A1

    公开(公告)日：2016-02-18

    申请号：PCT/US2015/045098

    申请日：2015-08-13

    Applicant: SENSIQ TECHNOLOGIES, INC.

    Inventor： STRANDE, Christopher, Iver

    IPC: G01N35/10

    CPC classification number: G01N35/1097 ,  G01N21/11 ,  G01N21/553 ,  G01N35/1095

    Abstract: A fluid delivery system and process for fluid delivery is provided that is useful in in flow- injection based sensing measurements, wherein samples from a sample rack are introduced into a flow cell where sensing measurements are taken. The system and process utilize at least two holding lines where each holding line can retain one of the samples prior to injection of the thus retained sample into a flow cell. The introduction of the samples from the sample racks to the holding lines is alternated and the injection of the samples from the holding lines to the flow cell are alternated so that one holding line is loaded with one of the samples simultaneously with another sample being injected from the another holding line to the flow cell.

    Abstract translation: 提供流体输送系统和用于流体输送的方法，其可用于基于流动注射的感测测量，其中来自样品架的样品被引入到进行感测测量的流动池中。 该系统和方法利用至少两条保持线，其中每条保持线可以在将如此保留的样品注入流动池之前保留其中一个样品。 将样品从样品架引入保持管线交替，将样品从保持管线注入到流动池中，使得一个保持管线与另一个样品同时加载另一个样品，从另一个样品注入 流动池的另一个保持线。

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